Association of resistin promoter polymorphisms with plasma resistin levels and type 2 diabetes in women and men

International Journal of Molecular Epidemiology and Genetics

Volumn 1, Issue 3, 2010, Pages 167-174

  Chen, Brian H ^a   Song, Yiqing ^b   Ding, Eric L ^c   Manson, Joann E ^b,c   Roberts, Christian K ^a,d   Rifai, Nader ^e   Buring, Julie E ^b,c,f   Gaziano, J Michael ^b,g   Liu, Simin ^a,h  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e BOSTON CHILDREN S HOSPITAL   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

^g VA BOSTON HEALTHCARE SYSTEM   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

BMI; CRP; Resistin; RETN; TNF RII; Type 2 diabetes

Indexed keywords

RESISTIN;

ADULT; AGED; ALCOHOL CONSUMPTION; ALLELE; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DNA POLYMORPHISM; EXERCISE; FAMILY HISTORY; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POSTMENOPAUSE; PROMOTER REGION; PROTEIN BLOOD LEVEL; RACE; RISK FACTOR; SEX DIFFERENCE; SMOKING;

EID: 77955675041     PISSN: None     EISSN: 19481756     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Banerjee RR, Rangwala SM, Shapiro JS, Rich AS, Rhoades B, Qi Y, Wang J, Rajala MW, Pocai A, Scherer PE, Steppan CM, Ahima RS, Obici S, Rossetti L and Lazar MA. Regulation of fasted blood glucose by resistin. Science 2004; 303: 1195-1198.
2. Kim KH, Zhao L, Moon Y, Kang C and Sul HS. Dominant inhibitory adipocyte-specific secretory factor (ADSF)/resistin enhances adipogenesis and improves insulin sensitivity. Proc Natl Acad Sci U S A 2004; 101: 6780-6785.
3. Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS and Lazar MA. The hormone resistin links obesity to diabetes. Nature 2001; 409: 307-312.
4. Chen BH, Song Y, Ding EL, Roberts CK, Manson JE, Rifai N, Buring JE, Gaziano JM and Liu S. Circulating levels of resistin and risk of type 2 diabetes in men and women: results from two prospective cohorts. Diabetes Care 2009; 32: 329-334.
5. Heidemann C, Sun Q, van Dam RM, Meigs JB, Zhang C, Tworoger SS, Mantzoros CS and Hu FB. Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in women. Ann Intern Med 2008; 149: 307-316.
6. Osawa H, Onuma H, Ochi M, Murakami A, Yamauchi J, Takasuka T, Tanabe F, Shimizu I, Kato K, Nishida W, Yamada K, Tabara Y, Yasukawa M, Fujii Y, Ohashi J, Miki T and Makino H. Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes. Biochem Biophys Res Commun 2005; 335: 596-602.
7. Savage DB, Sewter CP, Klenk ES, Segal DG, Vidal -Puig A, Considine RV and O'Rahilly S. Resistin/Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans. Diabetes 2001; 50: 2199-2202.
8. Lu HL, Wang HW, Wen Y, Zhang MX and Lin HH. Roles of adipocyte derived hormone adiponectin and resistin in insulin resistance of type 2 diabetes. World J Gastroenterol 2006; 12: 1747-1751.
9. Osawa H, Tabara Y, Kawamoto R, Ohashi J, Ochi M, Onuma H, Nishida W, Yamada K, Nakura J, Kohara K, Miki T and Makino H. Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population. Diabetes Care 2007; 30: 1501-1506.
10. Osawa H, Yamada K, Onuma H, Murakami A, Ochi M, Kawata H, Nishimiya T, Niiya T, Shimizu I, Nishida W, Hashiramoto M, Kanatsuka A, Fujii Y, Ohashi J and Makino H. The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3. Am J Hum Genet 2004; 75: 678-686.
11. Conneely KN, Silander K, Scott LJ, Mohlke KL, Lazaridis KN, Valle TT, Tuomilehto J, Bergman RN, Watanabe RM, Buchanan TA, Collins FS and Boehnke M. Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects. Diabetologia 2004; 47: 1782-1788.
12. Kunnari A, Ukkola O and Kesaniemi YA. Resistin polymorphisms are associated with cerebrovascular disease in Finnish Type 2 diabetic patients. Diabet Med 2005; 22: 583-589.
13. Cho YM, Youn BS, Chung SS, Kim KW, Lee HK, Yu KY, Park HJ, Shin HD and Park KS. Common genetic polymorphisms in the promoter of resistin gene are major determinants of plasma resistin concentrations in humans. Diabetologia 2004; 47: 559-565.
14. Ochi M, Osawa H, Hirota Y, Hara K, Tabara Y, Tokuyama Y, Shimizu I, Kanatsuka A, Fujii Y, Ohashi J, Miki T, Nakamura N, Kadowaki T, Ita-kura M, Kasuga M and Makino H. Frequency of the G/G genotype of resistin single nucleotide polymorphism at -420 appears to be increased in younger-onset type 2 diabetes. Diabetes 2007; 56: 2834-2838.
15. Azuma K, Oguchi S, Matsubara Y, Mamizuka T, Murata M, Kikuchi H, Watanabe K, Katsukawa F, Yamazaki H, Shimada A and Saruta T. Novel resistin promoter polymorphisms: association with serum resistin level in Japanese obese individuals. Horm Metab Res 2004; 36: 564-570.
16. Buring J and Hennekens C. The Women's Health Study: summary of the study design. J Myocardial Ischemia 1992; 4: 27-29.
17. Rexrode KM, Lee IM, Cook NR, Hennekens CH and Buring JE. Baseline characteristics of participants in the Women's Health Study. J Womens Health Gend Based Med 2000; 9: 19-27.
18. Christen WG, Gaziano JM and Hennekens CH. Design of Physicians' Health Study II--a randomized trial of beta-carotene, vitamins E and C, and multivitamins, in prevention of cancer, cardiovascular disease, and eye disease, and review of results of completed trials. Annals of epidemiology 2000; 10: 125-134.
19. Song Y, Manson JE, Buring JE and Liu S. A prospective study of red meat consumption and type 2 diabetes in middle-aged and elderly women: the women's health study. Diabetes Care 2004; 27: 2108-2115.
20. Liu S, Lee IM, Song Y, Van Denburgh M, Cook NR, Manson JE and Buring JE. Vitamin E and risk of type 2 diabetes in the women's health study randomized controlled trial. Diabetes 2006; 55: 2856-2862.
21. Ridker PM, Rifai N, Rose L, Buring JE and Cook NR. Comparison of C-reactive protein and lowdensity lipoprotein cholesterol levels in the prediction of first cardiovascular events. The New England journal of medicine 2002; 347: 1557-1565.
22. DerSimonian R and Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-188.
23. Asano H, Izawa H, Nagata K, Nakatochi M, Kobayashi M, Hirashiki A, Shintani S, Nishizawa T, Tanimura D, Naruse K, Matsubara T, Murohara T and Yokota M. Plasma resistin concentration determined by common variants in the resistin gene and associated with metabolic traits in an aged Japanese population. Diabetologia 2010; 53: 234-246.
24. Osawa H, Tabara Y, Kawamoto R, Ohashi J, Ochi M, Onuma H, Nishida W, Yamada K, Nakura J, Miki T, Makino H and Kohara K. PPARgamma Pro12Ala Pro/Pro and resistin SNP-420 G/G genotypes are synergistically associated with plasma resistin in the Japanese general population. Clin Endocrinol (Oxf) 2009; 71: 341-345.
25. Hivert MF, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB and Florez JC. Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study. Diabetes 2009; 58: 750-756.
26. Pizzuti A, Argiolas A, Di Paola R, Baratta R, Rauseo A, Bozzali M, Vigneri R, Dallapiccola B, Trischitta V and Frittitta L. An ATG repeat in the 3'-untranslated region of the human resistin gene is associated with a decreased risk of insulin resistance. J Clin Endocrinol Metab 2002; 87: 4403-4406.
27. Lehrke M, Reilly MP, Millington SC, Iqbal N, Rader DJ and Lazar MA. An inflammatory cascade leading to hyperresistinemia in humans. PLoS Med 2004; 1: e45.