Polygenic heterogeneity: A complex model of genetic inheritance in psychiatric disorders

Biological Psychiatry

Volumn 68, Issue 4, 2010, Pages 312-313

  Rucker, James J H ^a   McGuffin, Peter ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTISM; COPY NUMBER VARIATION; DNA MICROARRAY; DYSLEXIA; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; INDEL MUTATION; INHERITANCE; MENTAL DISEASE; NOTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

DNA COPY NUMBER VARIATIONS; HUMANS; MENTAL DISORDERS; MODELS, GENETIC; MULTIFACTORIAL INHERITANCE;

EID: 77955674340     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.06.020     Document Type: Note

References (13)

1. I.I. Gottesman, and J. Shields A polygenic theory of schizophrenia Proc Natl Acad Sci U S A 58 1967 199 205
2. D.S. Falconer The inheritance of liability to certain diseases, estimated from the incidence among relatives Ann Hum Genet 29 1965 51 76
3. A.G. Cardno, F.V. Rijsdijk, P.C. Sham, R.M. Murray, and P. McGuffin A twin study of genetic relationships between psychotic symptoms Am J Psychiatry 159 2002 539 545
4. A.T. Pagnamenta, E. Bacchelli, M.V. de Jonge, G. Mirza, T.S. Scerri, and F. Minopoli Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia Biol Psychiatry 68 2010 320 328
5. E.H.J. Cook, and S.W. Scherer Copy-number variations associated with neuropsychiatric conditions Nature 455 2008 919 923
6. L. Feuk, A.R. Carson, and S.W. Scherer Structural variation in the human genome Nat Rev Genet 7 2006 85 97
7. D.T. Miller, M.P. Adam, S. Aradhya, L.G. Biesecker, A.R. Brothman, and N.P. Carter Consensus statement: Chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies Am J Hum Genet 86 2010 749 764
8. S.W. Scherer, C. Lee, E. Birney, D.M. Altshuler, E.E. Eichler, and N.P. Carter Challenges and standards in integrating surveys of structural variation Nat Genet 39 2007 S7 S15
9. S. Levy, G. Sutton, P.C. Ng, L. Feuk, A.L. Halpern, and B.P. Walenz The diploid genome sequence of an individual human PLoS Biol 5 2007 e254
10. A. Bailey, A. Le Couteur, I. Gottesman, P. Bolton, E. Simonoff, E. Yuzda, and M. Rutter Autism as a strongly genetic disorder: Evidence from a British twin study Psychol Med 25 1995 63 77
11. S. Steffenburg, C. Gillberg, L. Hellgren, L. Andersson, I.C. Gillberg, G. Jakobsson, and M. Bohman A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden J Child Psychol Psychiatry 30 1989 405 416
12. J. Yang, B. Benyamin, B.P. McEvoy, S. Gordon, A.K. Henders, and D.R. Nyholt Common SNPs explain a large proportion of the heritability for human height Nat Genet 42 2010 565 569
13. T.A. Trikalinos, A. Karvouni, E. Zintzaras, T. Ylisaukko-oja, L. Peltonen, I. Jrvel, and J.P. Ioannidis A heterogeneity-based genome search meta-analysis for autism-spectrum disorders Mol Psychiatry 11 2006 29 36 (Pubitemid 43251085)