High efficiency CD91- and LOX-1-mediated re-presentation of gp96-chaperoned peptides by MHC II molecules

Cancer Immunity

Volumn 10, Issue , 2010, Pages 1-7

  Matsutake, Toyoshi ^a   Sawamura, Tatsuya ^b   Srivastava, Pramod K ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Cellular immunity; Heat shock proteins; Immunization; Mice; Peptides

Indexed keywords

CHAPERONE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PEPTIDE; VITESPEN; CD91 ANTIGEN, HUMAN; HEAT SHOCK PROTEIN; HLA ANTIGEN CLASS 2; LEUKOCYTE ANTIGEN; OLR1 PROTEIN, MOUSE; SARCOMA GLYCOPROTEIN GP96 REJECTION ANTIGENS; TUMOR ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE ACTIVATION; CD4 LYMPHOCYTE COUNT; CELL EXPANSION; CELL INTERACTION; CELLULAR IMMUNITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENDRITIC CELL; HELPER CELL; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; WILD TYPE; ANIMAL; BAGG ALBINO MOUSE; IMMUNOLOGY;

ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD; ANTIGENS, NEOPLASM; HEAT-SHOCK PROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS II; LDL-RECEPTOR RELATED PROTEIN 1; MICE; MICE, INBRED BALB C; MOLECULAR CHAPERONES; PEPTIDES; SCAVENGER RECEPTORS, CLASS E;

EID: 77955669767     PISSN: None     EISSN: 14249634     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Binder RJ, Han DK, Srivastava PK. CD91: a receptor for heat shock protein gp96. Nat Immunol 2000; 1: 151-155. (PMID: 11248808)
2. Basu S, Binder RJ, Ramalingam T, Srivastava PK. CD91 is a com-mon receptor for heat shock proteins gp96, hsp90, hsp70, and cal-reticulin. Immunity 2001; 14: 303-313. (PMID: 11290339)
3. Binder RJ, Srivastava PK. Essential role of CD91 in re-presentation of gp96-chaperoned peptides. Proc Natl Acad Sci USA 2004; 101: 6128-6133. (PMID: 15073331)
4. Delneste Y, Magistrelli G, Gauchat J, Haeuw J, Aubry J, Nakamura K, Kawakami-Honda N, Goetsch L, Sawamura T, Bonnefoy J, Jean-nin P. Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. Immunity 2002; 17: 353-362. (PMID: 12354387)
5. Srivastava PK, Udono H, Blachere NE, Li Z. Heat shock proteins transfer peptides during antigen processing and CTL prim ing. Immunogenetics 1994; 39: 93-98. (PMID: 8276462)
6. Suto R, Srivastava PK. A mechanism for the specific immunogenic-ity of heat shock protein-chaperoned peptides. Science 1995; 269: 1585-1588. (PMID: 7545313)
7. Castellino F, Boucher PE, Eichelberg K, Mayhew M, Rothman JE, Houghton AN, Germain RN. Receptor-mediated uptake of antigen/ heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways. J Exp Med 2000; 191: 1957-1964. (PMID: 10839810)
8. Castelli C, Ciupitu AM, Rini F, Rivoltini L, Mazzocchi A, Kiessling R, Parmiani G. Human heat shock protein 70 peptide complexes specifically activate antimelanoma T cells. Cancer Res 2001; 61: 222-227. (PMID: 11196165)
9. Noessner E, Gastpar R, Milani V, Brandl A, Hutzler PJ, Kuppner MC, Roos M, Kremmer E, Asea A, Calderwood SK, Issels RD. Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells. J Immunol 2002; 169: 5424-5432. (PMID: 12421917)
10. SenGupta D, Norris PJ, Suscovich TJ, Hassan-Zahraee M, Moffett HF, Trocha A, Draenert R, Goulder PJ, Binder RJ, Levey DL, Walker BD, Srivastava PK, Brander C. Heat shock protein-mediated cross-presentation of exogenous HIV antigen on HLA class I and class II. J Immunol 2004; 173: 1987-1993. (PMID: 15265933)
11. Lanzavecchia A. Antigen-specific interaction between T and B cells. Nature 1985; 314: 537-539. (PMID: 3157869)
12. Guermonprez P, Valladeau J, Zitvogel L, Théry C, Amigorena S. Antigen presentation and T cell stimulation by dendritic cells. Annu Rev Immunol 2002; 20: 621-667. (PMID: 11861614)
13. Mansour MK, Schlesinger LS, Levitz SM. Optimal T cell responses to Cryptococcus neoformans mannoprotein are dependent on rec-ognition of conjugated carbohydrates by mannose receptors. J Immunol 2002; 168: 2872-2879. (PMID: 11884457)
14. Jiang W, Swiggard WJ, Heufler C, Peng M, Mirza A, Steinman RM, Nussenzweig MC. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 1995; 375: 151-155. (PMID: 7753172)
15. Matsutake T, Srivastava PK. The immunoprotective MHC II epitope of a chemically induced tumor harbors a unique mutation in a ribosomal protein. Proc Natl Acad Sci USA 2001; 98: 3992-3997. (PMID: 11274422)
16. Nieland TJ, Tan MC, Monne-van Muijen M, Koning F, Kruisbeek AM, van Bleek GM. Isolation of an immunodominant viral peptide that is endogenously bound to the stress protein GP96/GRP94. Proc Natl Acad Sci USA 1996; 93: 6135-6139. (PMID: 8650232)
17. Udono H, Srivastava PK. Heat shock protein 70-associated peptides elicit specific cancer immunity. J Exp Med 1993; 178: 1391-1396. (PMID: 8376942)
18. Breloer M, Marti T, Fleischer B, von Bonin A. Isolation of pro-cessed, H-2Kb-binding ovalbumin-derived peptides associated with the stress proteins HSP70 and gp96. Eur J Immunol 1998; 28: 1016-1021. (PMID: 9541597)
19. Blachere NE, Li Z, Chandawarkar RY, Suto R, Jaikaria NS, Basu S, Udono H, Srivastava PK. Heat shock protein-peptide complexes, reconstituted in vitro, elicit peptide-specific cytotoxic T lymphocyte response and tumor immunity. J Exp Med 1997; 186: 1315-1322. (PMID: 9334371)
20. Moriwaki H, Kume N, Sawamura T, Aoyama T, Hoshikawa H, Ochi H, Nishi E, Masaki T, Kita T. Ligand specificity of LOX-1, a novel endothelial receptor for oxidized low density lipoprotein. Arterio-scler Thromb Vasc Biol 1998; 18: 1541-1547. (PMID: 9763524)
21. Lippincott-Schwartz J, Yuan L, Tipper C, Amherdt M, Orci L, Klausner RD. Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell 1991; 67: 601-616. (PMID: 1682055)
22. Harding CV, Collins DS, Slot JW, Geuze HJ, Unanue ER. Lipo-some-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells. Cell 1991; 64: 393-401. (PMID: 1899049)
23. Huang AY, Gulden PH, Woods AS, Thomas MC, Tong CD, Wang W, Engelhard VH, Pasternack G, Cotter R, Hunt D, Pardoll DM, Jaffee EM. The immunodominant major histocompatibility com-plex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product. Proc Natl Acad Sci USA 1996; 93: 9730-9735. (PMID: 8790399)
24. Basu S, Binder RJ, Suto R, Anderson KM, Srivastava PK. Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway. Int Immunol 2000; 12: 1539-1546. (PMID: 11058573)
25. Singh-Jasuja H, Scherer HU, Hilf N, Arnold-Schild D, Rammensee HG, Toes RE, Schild H. The heat shock protein gp96 induces matu-ration of dendritic cells and down-regulation of its receptor. Eur J Immunol 2000; 30: 2211-2215. (PMID: 10940912)
26. Binder RJ, Anderson KM, Basu S, Srivastava PK. Cutting edge: heat shock protein gp96 induces maturation and migration of CD11c+ cells in vivo. J Immunol 2000; 165: 6029-6035. (PMID: 11086034)
27. Singh-Jasuja H, Toes RE, Spee P, Münz C, Hilf N, Schoenberger SP, Ricciardi-Castagnoli P, Neefjes J, Rammensee HG, Arnold-Schild D, Schild H. Cross-presentation of glycoprotein 96-associated anti-gens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis. J Exp Med 2000; 191: 1965-1974. (PMID: 10839811)
28. Udono H, Levey DL, Srivastava PK. Cellular requirements for tumor-specific immunity elicited by heat shock proteins: tumor rejection antigen gp96 primes CD8+ T cells in vivo. Proc Natl Acad Sci U S A 1994; 91: 3077-3081. (PMID: 7909157)
29. Kumaraguru U, Gierynska M, Norman S, Bruce BD, Rouse BT. Immunization with chaperone-peptide complex induces low-avidity cytotoxic T lymphocytes providing transient protection against her-pes simplex virus infection. J Virol 2002; 76: 136-141. (PMID: 11739679)
30. Navaratnam M, Deshpande MS, Hariharan MJ, Zatechka DS Jr, Sri-kumaran S. Heat shock protein-peptide complexes elicit cytotoxic T-lymphocyte and antibody responses specific for bovine herpesvi-rus 1. Vaccine 2001; 19: 1425-1434. (PMID: 11163665)
31. Manjili MH, Henderson R, Wang XY, Chen X, Li Y, Repasky E, Kazim L, Subjeck JR. Development of a recombinant HSP110-HER- 2/neu vaccine using the chaperoning properties of HSP110. Cancer Res 2002; 62: 1737-1742. (PMID: 11912148)
32. Chandawarkar RY, Wagh MS, Srivastava PK. The dual nature of specific immunological activity of tumor-derived gp96 prepara-tions. J Exp Med 1999; 189: 1437-1442. (PMID: 10224283)
33. Chandawarkar RY, Wagh MS, Kovalchin JT, Srivastava P. Immune modulation with high-dose heat-shock protein gp96: therapy of murine autoimmune diabetes and encephalomyelitis. Int Immunol 2004; 16: 615-624. (PMID: 15039392)
34. Lehner T, Bergmeier LA, Wang Y, Tao L, Sing M, Spallek R, van der Zee R. Heat shock proteins generate beta-chemokines which function as innate adjuvants enhancing adaptive immunity. Eur J Immu-nol 2000; 30: 594-603. (PMID: 10671216)