Evaluation of in-line spatial filter velocimetry as PAT monitoring tool for particle growth during fluid bed granulation

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 76, Issue 1, 2010, Pages 138-146

  Burggraeve, A ^a   Van Den Kerkhof, T ^b   Hellings, M ^b   Remon, J P ^a   Vervaet, C ^a   De Beer, T ^a  

^a GHENT UNIVERSITY   (Belgium)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Fluid bed granulation; In line measurements; Particle size (distribution); Process analytical technology (PAT); Process understanding; Spatial filter velocimetry (SFV)

Indexed keywords

POLYSORBATE 20;

AIR TEMPERATURE; ANALYTIC METHOD; ARTICLE; DENSITY; FEASIBILITY STUDY; FLUID BED GRANULATION; LASER DIFFRACTION; PARTICLE SIZE; PHARMACEUTICAL ENGINEERING; PROCESS ANALYTICAL TECHNOLOGY; SPATIAL FILTER VELOCIMETRY; SPRAY DRYING;

EID: 77955661712     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.06.001     Document Type: Article

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