Time to blood culture positivity in Staphylococcus aureus bacteremia: Association with 30-day mortality

Journal of Infection

Volumn 61, Issue 3, 2010, Pages 197-204

  Kim, Joseph ^a   Gregson, Daniel B ^a,b   Ross, Terry ^b,c   Laupland, Kevin B ^a,b,c  

^a UNIVERSITY OF CALGARY   (Canada)

^b CALGARY LABORATORY SERVICES   (Canada)

^c Centre for Antimicrobial Resistance   (Canada)

Author keywords

Bacteremia; Staphylococcus aureus; Time to positivity

Indexed keywords

ADULT; AGE; AGED; ANTIMICROBIAL THERAPY; ARTICLE; BACTERIUM CULTURE; BLOOD CULTURE; CANADA; FATALITY; FEMALE; HOSPITAL INFECTION; HUMAN; INFECTION RISK; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; OUTCOME ASSESSMENT; PROGNOSIS; RETROSPECTIVE STUDY; STAPHYLOCOCCAL BACTEREMIA; STAPHYLOCOCCUS AUREUS;

EID: 77955660386     PISSN: 01634453     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinf.2010.06.001     Document Type: Article

References (31)

1. Laupland K.B., Gregson D.B., Zygun D.A., Doig C.J., Mortis G., Church D.L. Severe bloodstream infections: a population-based assessment. Crit Care Med 2004, 32:992-997.
2. Wisplinghoff H., Bischoff T., Tallent S.M., Seifert H., Wenzel R.P., Edmond M.B. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis 2004, 39:309-317.
3. Uslan D.Z., Crane S.J., Steckelberg J.M., Cockerill F.R., St.Sauver J.L., Wilson W.R., et al. Age and sex-associated trends in bloodstream infection: a population-based study in Olmsted County, Minnesota. Arch Intern Med 2007, 167:834-839.
4. Naber C.K. Staphylococcus aureus bacteremia: epidemiology, pathophysiology, and management strategies. Clin Infect Dis 2009, 48:S231-S237.
5. Hill P.C., Birch M., Chambers S., Drinkovic D., Ellis-Pegler R.B., Everts R., et al. Prospective study of 424 cases of Staphylococcus aureus bacteraemia: determination of factors affecting incidence and mortality. Intern Med J 2001, 31:97-103.
6. Lyytikäinen O., Ruotsalainen E., Järvinen A., Valtonen V., Ruutu P. Trends and outcome of nosocomial and community-acquired bloodstream infections due to Staphylococcus aureus in Finland, 1995-2001. Eur J Clin Microbiol Infect Dis 2005, 24:399-404.
7. Laupland K.B., Ross T., Gregson D.B. Staphylococcus aureus bloodstream infections: risk factors, outcomes, and the influence of methicillin resistance in Calgary, Canada, 2000-2006. J Infect Dis 2008, 198:336-343.
8. Mylotte J.M., Aeschlimann J.R., Rotella D.L. Staphylococcus aureus bacteremia: factors predicting hospital mortality. Infect Control Hosp Epidemiol 1996, 17:165-168.
9. McClelland R.S., Fowler V.G., Sanders L.L., Gottlieb G., Kong L.K., Sexton D., et al. Staphylococcus aureus bacteremia among elderly vs. younger adult patients: comparison of clinical features and mortality. Arch Intern Med 1999, 159:1244-1247.
10. Mylotte J.M., Tayara A. Staphylococcus aureus bacteremia: predictors of 30-day mortality in a large cohort. Clin Infect Dis 2000, 31:1170-1174.
11. Jensen A.G., Wachmann C.H., Espersen F., Scheibel J., Skinhøj P., Frimodt-Møller N. Treatment and outcome of Staphylococcus aureus bacteremia: a prospective study of 278 cases. Arch Intern Med 2002, 162:25-32.
12. Blot F., Schmidt E., Nitenberg G., Tancrede C., Leclercq B., Laplanche A., et al. Earlier positivity of central-venous- versus peripheral-blood cultures is highly predictive of catheter-related sepsis. J Clin Microbiol 1998, 36:105-109.
13. Rogers M.S., Oppenheim B.A. The use of continuous monitoring blood culture systems in the diagnosis of catheter related sepsis. J Clin Pathol 1998, 51:635-637.
14. Norris C.F., Smith-Whitley K., McGowan K.L. Positive blood cultures in sickle cell disease: time to positivity and clinical outcome. J Pediatr Hematol Oncol 2003, 25:390-395.
15. Ruimy R., Armand-Lefevre L., Andremont A. Short time to positivity in blood culture with clustered gram-positive cocci on direct smear examination is highly predictive of Staphylococcus aureus. Am J Infect Control 2005, 33:304-306.
16. Khatib R., Riederer K., Saeed S., Johnson L.B., Fakih M.G., Sharma M., et al. Time to positivity in Staphylococcus aureus bacteremia: possible correlation with the source and outcome of infection. Clin Infect Dis 2005, 41:594-598.
17. Marra A.R., Edmond M.B., Forbes B.A., Wenzel R.P., Bearman G.M. Time to blood culture positivity as a predictor of clinical outcome of Staphylococcus aureus bloodstream infection. J Clin Microbiol 2006, 44:1342-1346.
18. Sowden D., Anstey C., Faddy M. Blood culture time to positivity as a predictor of mortality in community acquired methicillin-susceptible Staphylococcus aureus bacteremia. J Infect 2008, 56:295-296. doi:10.1016/j.jinf.2008.01.011.
19. Friedman N.D., Kaye K.S., Stout J.E., McGarry S.A., Trivette S.L., Briggs J.P., et al. Health care-associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections. Ann Intern Med 2002, 137:791-797.
20. Laupland K.B., Church D.L., Mucenski M., Sutherland L.R., Davies H.D. Population-based study of the epidemiology of and the risk factors for invasive Staphylococcus aureus infections. J Infect Dis 2003, 187:1452-1459.
21. Charlson M.E., Pompei P., Ales K.L., MacKenzie C.R. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987, 40:373-383.
22. Quan H., Sundararajan V., Halfon P., Fong A., Burnand B., Luthi J.C., et al. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care 2005, 43:1130-1139.
23. Clinical and Laboratory Standards Institute Performance standards for antimicrobial susceptibility testing 2007, 17th informational supplement. CLSI document MS 100-S17, CLSI, Wayne, PA.
24. Vannuffel P., Gigi J., Ezzedine H., Vandercam B., Delmee M., Wauters G., et al. Specific detection of methicillin-resistant Staphylococcus aureus species by multiplex PCR. J Clin Microbiol 1995, 33:2864-2867.
25. Lesens O., Methlin C., Hansmann Y., Remy V., Martinot M., Bergin C., et al. Role of comorbidity in mortality related to Staphylococcus aureus bacteremia: a prospective study using the Charlson weighted index of comorbidity. Infect Control Hosp Epidemiol 2003, 24:890-896.
26. Conterno L.O., Wey S.B., Castelo A. Risk factors for mortality in Staphylococcus aureus bacteremia. Infect Control Hosp Epidemiol 1998, 19:32-37.
27. Cosgrove S.E., Sakoulas G., Perencevich E.N., Schwaber M.J., Karchmer A.W., Carmeli Y. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clin Infect Dis 2003, 36:53-59.
28. Turnidge J.D., Kotsanas D., Munckhof W., Roberts S., Bennett C.M., Nimmo G.R., et al. Staphylococcus aureus bacteraemia: a major cause of mortality in Australia and New Zealand. Med J Aust 2009, 191:368-373.
29. Lodise T.P., McKinnon P.S., Swiderski L., Rybak M.J. Outcomes analysis of delayed antibiotic treatment for hospital-acquired Staphylococcus aureus bacteremia. Clin Infect Dis 2003, 36:1418-1423.
30. Khatib R., Saeed S., Sharma M., Riederer K., Fakih M.G., Johnson L.B. Impact of initial antibiotic choice and delayed appropriate treatment on the outcome of Staphylococcus aureus bacteremia. Eur J Clin Microbiol Infect Dis 2006, 25:181-185.
31. Mermel L., Allon M., Bouza E., Craven D.E., Flynn P., O'Grady N.P., et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the infectious diseases Society of America. Clin Infect Dis 2009, 49:1-45.