The demographic and biomedical case for late-life interventions in aging

Science Translational Medicine

Volumn 2, Issue 40, 2010, Pages

  Rae, Michael J ^a   Butler, Robert N ^b   Campisi, Judith ^c   De Grey, Aubrey D N J ^a   Finch, Caleb E ^d   Gough, Michael ^h   Martin, George M ^e   Vijg, Jan ^f   Perrott, Kevin M ^g   Logan, Barbara J ^g  

^a Strategies for Engineered Negligible Senescence (SENS) Foundation   (United States)

^b International Longevity Center   (United States)

^c BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

^f ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^g LifeStar Institute   (United States)

^h NONE

Author keywords

[No Author keywords available]

Indexed keywords

AGING; DEMOGRAPHY; FUNDING; HEALTH CARE COST; HOMEOSTASIS; HUMAN; INCIDENCE; LIFESPAN; LIFESTYLE; MEDICAL RESEARCH; MORBIDITY; MORTALITY; NONHUMAN; NOTE; PREVALENCE; PRIORITY JOURNAL; PUBLIC HEALTH; REGENERATIVE MEDICINE; SOCIAL ASPECT; AGED; ARTICLE; DRUG EFFECT; ECONOMICS; HEALTH CARE POLICY; LEGAL ASPECT; LONGEVITY; PATHOLOGY; PHYSIOLOGY; STATISTICS;

AGED; AGING; DEMOGRAPHY; HEALTH POLICY; HUMANS; LONGEVITY; PUBLIC HEALTH; REGENERATIVE MEDICINE;

EID: 77955650664     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3000822     Document Type: Note

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35. Dedicated to the memory of our coauthor and friend, Robert N. Butler, a giant in his lifelong contributions who epitomized the value of healthy human longevity through tireless advocacy for aging research to the very end. Among his many accomplishments, Dr. Butler was the first director of the National Institute on Aging. We are privileged to have shared the creation of this publication with him and take comfort that it represents so much of what he worked for. He will be sorely missed. Acknowledgments: The authors thank A. Foster for yeoman's work in preparing and repeatedly revising the figures for this paper. Origin of paper: This meeting report is the result of a workshop held on 7 and 8 August 2009, sponsored and organized by the LifeStar Institute, a 501(c)3 nonprofit organization whose World Health Initiative is dedicated to mitigating the enormous economic, social, and human costs of global aging by ensuring that therapies are developed and made available globally which restore physiological (including cognitive) function in already-mature people, on the unprecedented schedule and scale dictated by the imminent surge in the world's elder demographic. Funding: C.E.F. is funded by the Ellison Medical Foundation and the National Institute on Aging. G.M.M. is funded by NIH grant R24CA078088. Competing interests: M.J.R. is a research assistant to A.D.N.J. de G., an employee of SENS Foundation, and a member of the Calorie Restriction Society. R.N.B. has a financial interest in BioTime, Inc. A.D.N.J. de G. is the chief science officer for SENS Foundation, a charity dedicated to furthering the development of regenerative medicine solutions to the problems of age-related ill health. C.E.F. has a financial relationship with Acumen Pharmaceuticals and a paid consulting relationship with the Ellison Medical Foundation and the CureAlzheimer Foundation. G.M.M. is the scientific director of the American Federation for Aging Research, the chair of the Scientific Advisory Board of and a paid consultant for the Ellison Medical Foundation, and a consultant for Icogenix Corporation and LifeSpan BioSciences. K.M.P. is a member of the board of directors of SENS Foundation. B.J.L. is the acting chair of SENS Foundation Board and chief executive officer of the LifeStar Institute.