Toward a B-cell signature of tolerance

Kidney International

Volumn 78, Issue 5, 2010, Pages 435-437

  Cugini, Daniela ^a   Noris, Marina ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 2; PROTEIN KINASE B; T LYMPHOCYTE RECEPTOR;

APOPTOSIS; B LYMPHOCYTE; CD4+ CD25+ T LYMPHOCYTE; CELL PROLIFERATION; GENE EXPRESSION; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; IMMUNE DEFICIENCY; IMMUNOCOMPETENT CELL; IMMUNOLOGICAL TOLERANCE; KIDNEY GRAFT; NOTE; ORGAN TRANSPLANTATION; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE;

EID: 77955626460     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2010.159     Document Type: Note

References (14)

1. Salama AD, Remuzzi G, Harmon WE et al. Challenges to achieving clinical transplantation tolerance. J Clin Invest 2001; 108: 943-948.
2. Ansari MJ, Sayegh MH. Clinical transplantation tolerance: the promise and challenges. Kidney Int 2004; 65: 1560-1563.
3. Martinez-Llordella M, Puig-Pey I, Orlando G et al. Multiparameter immune profiling of operational tolerance in liver transplantation. Am J Transplant 2007; 7: 309-319.
4. Li Y, Koshiba T, Yoshizawa A et al. Analyses of peripheral blood mononuclear cells in operational tolerance after pediatric living donor liver transplantation. Am J Transplant 2004; 4: 2118-2125.
5. + T cells/FOXP3 patterns in chronic rejection and operational drug-free tolerance. Transplantation 2006; 81: 398-407.
6. Brouard S, Dupont A, Giral M et al. Operationally tolerant and minimally immunosuppressed kidney recipients display strongly altered blood T-cell clonal regulation. Am J Transplant 2005; 5: 330-340.
7. Baeten D, Louis S, Braud C et al. Phenotypically and functionally distinct CD8+ lymphocyte populations in long-term drug-free tolerance and chronic rejection in human kidney graft recipients. J Am Soc Nephrol 2006; 17: 294-304.
8. Brouard S, Mansfield E, Braud C et al. Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance. Proc Natl Acad Sci USA 2007; 104: 15448-15453.
9. Pallier A, Hillion S, Danger R et al. Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype. Kidney Int 2010; 78: 503-513.
10. Bouaziz JD,Yanaba K, TedderTF. Regulatory B cells as inhibitors of immune responses and inflammation. Immunol Rev 2008; 224: 201-214.
11. Zhao G, Moore DJ, Lee KM et al. An unexpected counter-regulatory role of IL-10 in B-lymphocyte-mediated transplantation tolerance. Am J Transplant 2010; 10: 796-801.
12. Ravetch JV, Lanier LL. Immune inhibitory receptors. Science 2000; 290: 84-89.
13. Aiba Y, Yamazaki T, Okada T et al. BANK negatively regulates Akt activation and subsequent B cell responses. Immunity 2006; 24: 259-268.
14. Porcheray F, Wong W, Saidman SL et al. B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am J Transplant 2009; 9: 2126-2135.