"Chronic cerebrospinal venous insufficiency" and multiple sclerosis. Critical analysis and first observation in an unselected cohort of MS patients;"Chronische zerebrospinale venöse insuffizienz" und multiple sklerose: Kritische analyse und erste untersuchungen an einem unselektierten MS-kollektiv

Nervenarzt

Volumn 81, Issue 6, 2010, Pages 740-746

  Krogias, C ^a   Schroder A ^a   Wiendl, H ^b   Hohlfeld, R ^c   Gold, R ^a  

^a ST JOSEF HOSPITAL   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Cervical veins; Chronic cerebrospinal venous insufficiency; Multiple sclerosis; Ultrasound; Venous insufficiency

Indexed keywords

BLOOD BRAIN BARRIER; CEREBROVASCULAR DISEASE; CHRONIC CEREBROSPINAL VENOUS INSUFFICIENCY; ECHOENCEPHALOGRAPHY; ENDOVASCULAR SURGERY; HUMAN; INTERNAL JUGULAR VEIN; INTRACRANIAL HYPERTENSION; MULTIPLE SCLEROSIS; REVIEW; VEIN OCCLUSION; ADULT; AGED; BRAIN; BRAIN VEIN; CHRONIC DISEASE; COHORT ANALYSIS; COMPLICATION; DOPPLER ECHOGRAPHY; ECHOGRAPHY; FEMALE; HEMODYNAMICS; JUGULAR VEIN; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; RISK FACTOR; SPINAL CORD; STENOSIS, OCCLUSION AND OBSTRUCTION; VASCULARIZATION; VEIN INSUFFICIENCY;

ADULT; AGED; BLOOD-BRAIN BARRIER; BRAIN; CEREBRAL VEINS; CHRONIC DISEASE; COHORT STUDIES; CONSTRICTION, PATHOLOGIC; FEMALE; HEMODYNAMICS; HUMANS; JUGULAR VEINS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; RISK FACTORS; SPINAL CORD; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; VENOUS INSUFFICIENCY;

EID: 77955622231     PISSN: 00282804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00115-010-2972-1     Document Type: Review

References (30)

1. Ackermann Z, Seidenbaum M, Loewenthal E, Rubinow A (1988) Overload of iron in the skin of patients with varicose ulcers. Possible contributing role of iron accumulation in progression of the disease. Arch Dermatol 124:1376-1378
2. Adams CW, Poston RN, Buk SJ (1989) Pathology, histochemistry and immunocytochemistry of lesions in acute multiple sclerosis. J Neurol Sci 92:291-306
3. Colleridge-Smith PD, Thomas P, Scurr JH, Domandy JA (1988) Causes of venous ulceration: a new hypothesis. BMJ 296:1726-1727
4. Doepp F, Schreiber SJ, Münster T Von et al (2004) How does the blood leave the brain? A systematic ultrasound analysis of cerebral venous drainage patterns. Neuroradiology 46:565-570
5. Doepp F, Schreiber JS, Valdueza JM (2007) Incompetence of internal jugular vein valve in patients with primary exertional headache: a risk factor? Cephalalgia 28:182-185
6. Engelhardt B (2006) Molecular mechanisms involved in T cell migration across the blood-brain barrier. J Neural Transm 113:477-485
7. Fog T (1965) The topography of plaques in multiple sclerosis with special reference to cerebral plaques. Acta Neurol Scand 15 [Suppl]:1-161
8. Gay D, Esiri M (1991) Blood-brain barrier damage in acute multiple sclerosis plaques. An immunocytological study. Brain 114:557-572
9. Ge Y, Zohrabian VM, Grossman RI (2008) Seven-tesla magnetic resonance imaging: new vision of microvascular abnormalities in multiple sclerosis. Arch Neurol 65:812-816
10. Gold R, Rieckmann P (2005) Pathogenese und Therapie der Multiplen Sklerose. 3. Aufl. UNI-MED, Bremen
11. Hoffmann O, Weih M, Münster T Von et al (1999) Blood flow velocities in the vertebral veins of healthy subjects: a duplex sonographic study. J Neuroimaging 9:198-200
12. Kidd D, Barkhof F, McConnell R et al (1999) Cortical lesions in multiple sclerosis. Brain 122:17-26
13. Kuenz B, Lutterotti A, Khalil M et al (2005) Plasma levels of soluble adhesion molecules sPECAM-1, sP-selectin and sE-selectin are associated with relapsing-remitting disease course of multiple sclerosis. J Neuroimmunol 167:143-149
14. Lassmann H, Brück W, Lucchinetti CF (2007) The immunopathology of multiple sclerosis: an overview. Brain Pathol 17:210-218
15. Martino G, Adorini L, Rieckmann P et al (2002) Inflammation in multiple sclerosis: the good, the bad, and the complex. Lancet Neurol 1:499-509
16. Miller DH, Barkhof F, Nauta JJP (1993) Gadolinium enhancement increases the sensitivity of MRI in detecting disease activity in multiple sclerosis. Brain 116:1077-1094
17. Mueller HR, Hinn G, Buser MW (1990) Internal jugular venous flow measurement by means of a duplex scanner. J Ultrasound Med 9:261-265
18. Nadelmann M, Eicke BM, Dieterich M (2005) Functional and morphological criteria of internal jugular valve insufficiency as assessed by ultrasound. J Neuroimaging 15:70-75
19. Schreiber SJ, Doepp F, Klingebiel R, Valdueza JM (2005) Internal jugular vein valve incompetence and intracranial venous anatomy in transient global amnesia. J Neurol Neurosurg Psychiatry 76:509-513
20. Singh AV, Zamboni P (2009) Anomalous venous blood flow and iron depositino in multiple sclerosis. J Cereb Blood Flow Metab 29:1867-1878
21. Stolz E, Kaps M, Kern A et al (1999) Transcranial color-coded duplex sonography of intracranial veins and sinuses in adults. Reference data from 130 volunteers. Storke 30:1070-1075
22. Stolz E, Babacan SS, Bodecker RH et al (2001) Interobserver and intraobserverreliability of venous trancranial color-coded flow velocity. J Neuroimaging 11:385-392
23. Takase S, Pascarella L, lerond L et al (2004) Venous hypertension, inflammation and valve remodelling. Eur J Vasc Endovasc Surg 28:484-493
24. Valdueza JM, Munster T Von, Hoffman O et al (2000) Postural dependency of the cerebral venous outflow. Lancet 355:200-201
25. Walter U, Wagner S, Horowski S et al (2009) Transcranial brain sonography findings predict disease progression in multiple sclerosis. Neurology 73:1010-1017
26. Weilbach FX, Chan A, Toyka KV, Gold R (2004) The cardioprotector dexrazoxane augments therapeutic efficacy of mitoxantrone in experimental autoimmune encephalomyelitis. Clin Exp Immunol 135:49-55
27. Wilkinson LS, Bunker C, Edwards JC et al (1993) Leukocytes: their role in the etiopathogenesis of skin damage in venous disease. J Vasc Surg 17:669-675
28. Zamboni P (2006) The big idea: Iron-dependent inflammation in venous disease and proposed parallels in multiple sclerosis. J R Soc Med 99:589-593
29. Zamboni P, Galeotti R, Menegatti E et al (2009) Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry 80:392-399
30. Zamboni P, Galeotti R, Menegatti E et al (2009) A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency. J Vasc Surg 50:1348-1358