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Volumn 21, Issue 10, 2010, Pages 1961-1966

p16 expression in oropharyngeal cancer: Its impact on staging and prognosis compared with the conventional clinical staging parameters

Author keywords

HPV; Oropharyngeal carcinoma; p16; Prognosis; Staging

Indexed keywords

PROTEIN P16;

EID: 77955621988     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdq210     Document Type: Article
Times cited : (106)

References (27)
  • 1
    • 2342592623 scopus 로고    scopus 로고
    • Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer
    • Bernier J, Domenge C, Ozsahin M et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004; 350: 1945-1952.
    • (2004) N Engl J Med , vol.350 , pp. 1945-1952
    • Bernier, J.1    Domenge, C.2    Ozsahin, M.3
  • 2
    • 2342517421 scopus 로고    scopus 로고
    • Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck
    • Cooper JS, Pajak TF, Forastiere AA et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004; 350: 1937-1944.
    • (2004) N Engl J Med , vol.350 , pp. 1937-1944
    • Cooper, J.S.1    Pajak, T.F.2    Forastiere, A.A.3
  • 3
    • 42549161808 scopus 로고    scopus 로고
    • Human papillomavirus accounts both for increased incidence and better prognosis in tonsillar cancer
    • Dahlstrand H, Nasman A, Romanitan M et al. Human papillomavirus accounts both for increased incidence and better prognosis in tonsillar cancer. Anticancer Res 2008; 28: 1133-1138.
    • (2008) Anticancer Res , vol.28 , pp. 1133-1138
    • Dahlstrand, H.1    Nasman, A.2    Romanitan, M.3
  • 4
    • 0036722656 scopus 로고    scopus 로고
    • Incidence and survival of squamous cell carcinoma of the tongue in Scandinavia, with special reference to young adults
    • Annertz K, Anderson H, Biorklund A et al. Incidence and survival of squamous cell carcinoma of the tongue in Scandinavia, with special reference to young adults. Int J Cancer 2002; 101: 95-99.
    • (2002) Int J Cancer , vol.101 , pp. 95-99
    • Annertz, K.1    Anderson, H.2    Biorklund, A.3
  • 6
    • 33644849030 scopus 로고    scopus 로고
    • Molecular classification identifies a subset of human papillomavirus-associated oropharyngeal cancers with favorable prognosis
    • Weinberger PM, Yu Z, Haffty BG et al. Molecular classification identifies a subset of human papillomavirus-associated oropharyngeal cancers with favorable prognosis. J Clin Oncol 2006; 24: 736-747.
    • (2006) J Clin Oncol , vol.24 , pp. 736-747
    • Weinberger, P.M.1    Yu, Z.2    Haffty, B.G.3
  • 7
    • 0142122353 scopus 로고    scopus 로고
    • A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5-8
    • Hafkamp HC, Speel EJ, Haesevoets A et al. A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5-8. Int J Cancer 2003; 107: 394-400.
    • (2003) Int J Cancer , vol.107 , pp. 394-400
    • Hafkamp, H.C.1    Speel, E.J.2    Haesevoets, A.3
  • 8
    • 0041592494 scopus 로고    scopus 로고
    • Human papillomavirus positivity predicts favourable outcome for squamous carcinoma of the tonsil
    • Li W, Thompson CH, O'Brien CJ et al. Human papillomavirus positivity predicts favourable outcome for squamous carcinoma of the tonsil. Int J Cancer 2003; 106: 553-558.
    • (2003) Int J Cancer , vol.106 , pp. 553-558
    • Li, W.1    Thompson, C.H.2    O'Brien, C.J.3
  • 9
    • 70350663328 scopus 로고    scopus 로고
    • Prognostic significance of HPV and p16 status in patients with oropharyngeal cancer treated on a large international phase III trial
    • Rischin D, Young R, Fisher R et al. Prognostic significance of HPV and p16 status in patients with oropharyngeal cancer treated on a large international phase III trial. J Clin Oncol 2009; 27: 6004.
    • (2009) J Clin Oncol , vol.27 , pp. 6004
    • Rischin, D.1    Young, R.2    Fisher, R.3
  • 10
    • 0035408307 scopus 로고    scopus 로고
    • Human papillomavirus infection and survival in oral squamous cell cancer: a population-based study
    • Schwartz SR, Yueh B, McDougall JK et al. Human papillomavirus infection and survival in oral squamous cell cancer: a population-based study. Otolaryngol Head Neck Surg 2001; 125: 1-9.
    • (2001) Otolaryngol Head Neck Surg , vol.125 , pp. 1-9
    • Schwartz, S.R.1    Yueh, B.2    McDougall, J.K.3
  • 11
    • 0034690490 scopus 로고    scopus 로고
    • Human papillomavirus (HPV) DNA in tonsillar cancer: clinical correlates, risk of relapse, and survival
    • Mellin H, Friesland S, Lewensohn R et al. Human papillomavirus (HPV) DNA in tonsillar cancer: clinical correlates, risk of relapse, and survival. Int J Cancer 2000; 89: 300-304.
    • (2000) Int J Cancer , vol.89 , pp. 300-304
    • Mellin, H.1    Friesland, S.2    Lewensohn, R.3
  • 12
    • 33947140297 scopus 로고    scopus 로고
    • Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer
    • Reimers N, Kasper HU, Weissenborn SJ et al. Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer. Int J Cancer 2007; 120: 1731-1738.
    • (2007) Int J Cancer , vol.120 , pp. 1731-1738
    • Reimers, N.1    Kasper, H.U.2    Weissenborn, S.J.3
  • 13
    • 74049141163 scopus 로고    scopus 로고
    • Is the improved prognosis of p16 positive oropharyngeal squamous cell carcinoma dependent of the treatment modality?
    • Fischer CA, Zlobec I, Green E et al. Is the improved prognosis of p16 positive oropharyngeal squamous cell carcinoma dependent of the treatment modality? Int J Cancer 2010; 126: 1256-1262.
    • (2010) Int J Cancer , vol.126 , pp. 1256-1262
    • Fischer, C.A.1    Zlobec, I.2    Green, E.3
  • 14
    • 28444464387 scopus 로고    scopus 로고
    • P16(INK4a) correlates to human papillomavirus presence, response to radiotherapy and clinical outcome in tonsillar carcinoma
    • Mellin DH, Lindquist D, Bjornestal L et al. P16(INK4a) correlates to human papillomavirus presence, response to radiotherapy and clinical outcome in tonsillar carcinoma. Anticancer Res 2005; 25: 4375-4383.
    • (2005) Anticancer Res , vol.25 , pp. 4375-4383
    • Mellin, D.H.1    Lindquist, D.2    Bjornestal, L.3
  • 15
    • 39649109915 scopus 로고    scopus 로고
    • Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial
    • Fakhry C, Westra WH, Li S et al. Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 2008; 100: 261-269.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 261-269
    • Fakhry, C.1    Westra, W.H.2    Li, S.3
  • 16
    • 34247331367 scopus 로고    scopus 로고
    • High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma
    • Licitra L, Perrone F, Bossi P et al. High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma. J Clin Oncol 2006; 24: 5630-5636.
    • (2006) J Clin Oncol , vol.24 , pp. 5630-5636
    • Licitra, L.1    Perrone, F.2    Bossi, P.3
  • 18
    • 85047700479 scopus 로고    scopus 로고
    • Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control
    • Wiest T, Schwarz E, Enders C et al. Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control. Oncogene 2002; 21: 1510-1517.
    • (2002) Oncogene , vol.21 , pp. 1510-1517
    • Wiest, T.1    Schwarz, E.2    Enders, C.3
  • 19
    • 0028034775 scopus 로고
    • Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb
    • Li Y, Nichols MA, Shay JW, Xiong Y. Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb. Cancer Res 1994; 54: 6078-6082.
    • (1994) Cancer Res , vol.54 , pp. 6078-6082
    • Li, Y.1    Nichols, M.A.2    Shay, J.W.3    Xiong, Y.4
  • 20
    • 0036141797 scopus 로고    scopus 로고
    • Clinicopathological significance of p16 gene expression in the surgical treatment of head and neck squamous cell carcinomas
    • Yuen PW, Man M, Lam KY, Kwong YL. Clinicopathological significance of p16 gene expression in the surgical treatment of head and neck squamous cell carcinomas. J Clin Pathol 2002; 55: 58-60.
    • (2002) J Clin Pathol , vol.55 , pp. 58-60
    • Yuen, P.W.1    Man, M.2    Lam, K.Y.3    Kwong, Y.L.4
  • 21
    • 4444288693 scopus 로고    scopus 로고
    • Prognostic significance of p16 protein levels in oropharyngeal squamous cell cancer
    • Weinberger PM, Yu Z, Haffty BG et al. Prognostic significance of p16 protein levels in oropharyngeal squamous cell cancer. Clin Cancer Res 2004; 10: 5684-5691.
    • (2004) Clin Cancer Res , vol.10 , pp. 5684-5691
    • Weinberger, P.M.1    Yu, Z.2    Haffty, B.G.3
  • 22
    • 43049097865 scopus 로고    scopus 로고
    • Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas
    • Hafkamp HC, Manni JJ, Haesevoets A et al. Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas. Int J Cancer 2008; 122: 2656-2664.
    • (2008) Int J Cancer , vol.122 , pp. 2656-2664
    • Hafkamp, H.C.1    Manni, J.J.2    Haesevoets, A.3
  • 23
    • 70350656518 scopus 로고    scopus 로고
    • Survival outcomes by tumor human papillomavirus (HPV) status in stage III-IV oropharyngeal cancer (OPC) in RTOG 0129
    • Gillison ML, Harris L, Westra W et al. Survival outcomes by tumor human papillomavirus (HPV) status in stage III-IV oropharyngeal cancer (OPC) in RTOG 0129. J Clin Oncol 2009; 27: 6003.
    • (2009) J Clin Oncol , vol.27 , pp. 6003
    • Gillison, M.L.1    Harris, L.2    Westra, W.3
  • 24
    • 23844455665 scopus 로고    scopus 로고
    • 18F-FDG PET and CT/MRI in oral cavity squamous cell carcinoma: a prospective study of 124 patients with histologic correlation
    • Ng SH, Yen TC, Liao CT et al. 18F-FDG PET and CT/MRI in oral cavity squamous cell carcinoma: a prospective study of 124 patients with histologic correlation. J Nucl Med 2005; 46: 1136-43.
    • (2005) J Nucl Med , vol.46 , pp. 1136-1143
    • Ng, S.H.1    Yen, T.C.2    Liao, C.T.3
  • 25
    • 35348887678 scopus 로고    scopus 로고
    • Detection of lymph node metastases in head and neck cancer: a meta-analysis comparing US, USgFNAC
    • de Bondt RB, Nelemans PJ, Hofman PA et al. Detection of lymph node metastases in head and neck cancer: a meta-analysis comparing US, USgFNAC, CT and MR imaging. Eur J Radiol 2007; 64: 266-272.
    • (2007) CT and MR imaging. Eur J Radiol , vol.64 , pp. 266-272
    • de Bondt, R.B.1    Nelemans, P.J.2    Hofman, P.A.3
  • 26
    • 0029818332 scopus 로고    scopus 로고
    • The incidence of micrometastases in neck dissection specimens obtained from elective neck dissections
    • van den Brekel MW, van der Waal I, Meijer CJ et al. The incidence of micrometastases in neck dissection specimens obtained from elective neck dissections. Laryngoscope 1996; 106: 987-991.
    • (1996) Laryngoscope , vol.106 , pp. 987-991
    • van den Brekel, M.W.1    van der Waal, I.2    Meijer, C.J.3
  • 27
    • 23644432019 scopus 로고    scopus 로고
    • REporting recommendations for tumour MARKer prognostic studies (REMARK)
    • McShane LM, Altman DG, Sauerbrei W et al. REporting recommendations for tumour MARKer prognostic studies (REMARK). Eur J Cancer 2005; 41: 1690-1696.
    • (2005) Eur J Cancer , vol.41 , pp. 1690-1696
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.