Studies of behavioural and neural mechanism of aridanin isolated from Tetrapleura tetraptera in Mice

International Journal of Pharmacology

Volumn 6, Issue 4, 2010, Pages 470-476

  Aderibigbe, A O ^a   Iwalewa, E O ^b   Adesma, S K ^b   Agboola, O I ^a  

^a NIGER DELTA UNIVERSITY   (Nigeria)

^b OBAFEMI AWOLOWO UNIVERSITY   (Nigeria)

Author keywords

Aridanin; Hole board; Open field; Rearing; Tetrapleura tetraptera; Y maze

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ARIDANIN; DIAZEPAM; FLUMAZENIL; POLYSORBATE 80;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEPRESSION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; LOCOMOTION; MAZE TEST; MOUSE; NEUROTRANSMISSION; NONHUMAN; OPEN FIELD BEHAVIOR; OPEN FIELD TEST; REARING; SEDATION; SHORT TERM MEMORY; TETRAPLEURA; TETRAPLEURA TETRAPTERA; TOXICITY TESTING;

EID: 77955609176     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2010.480.486     Document Type: Article

References (42)

1. Adebayo, A.S., I.A. Gbadomosi and C.O. Adewunmi, 2000. Formulation of antimicrobial dried powered herbs in soap basis. Proceedings of the Phyto Medicines in Malaria and Sexually Transmitted Disease, Challenges for the New Millenium, (PMMSTDC'00), Obafemi Awolowo University, Ile-Ife, pp: 97-97.
2. Aderibigbe, A.O., E.O. Iwalewa, S.K. Adesina, A.O. Adebanjo and O.E. Ukponmwan, 2007a. Neuropharmacological evaluation of Aridanin a Glycoside isolated from Tetrapleura tetraptera fruit. Disc. Innol., 19: 177-181.
3. Aderibigbe, A.O., E.O. Iwalewa, S.K. Adesina, A.O. Adebanjo and O.E. Ukponmwan, 2007b. Anticonvulsant, analgesic and hypothermic effects of Aridanin isolated from Tetrapleura tetrapetra fruit in mice. J. Boil. Sci., 7: 1520-1524.
4. Adesina, S.K. and J.A. Reisch, 1985. Triterpenoid glycoside from Tetrapleura tetraptera fruit. Phytochemistiy, 24: 3003-3006.
5. Adewunmi, C.O., 1991. Plant molluscicides: Potentual of Aridanin, Tetrapleura tetraptera for schistosomiasis control in Nigeria. Sci. Total Environ., 103: 21-33.
6. Adewunmi, C.O., H.C. Anderson and L. Busk, 1991. Potential molluscicides, aridan (Tetrapleura tetraptera), neither induces chromosomal alterations in Chinese hamster ovaiy cells, nor mutation in Salmonella typhimurium. Toxicol. Environ. Chem., 30: 69-74.
7. Ajayi, A.A. and O.E. Ukponmwan, 1994. Evidence of angiotensin 11 and endogenous opioid modulation of novelty induced rearing in the rat. Afr. J. Med. Med. Sci., 23: 287-290.
8. Akanmu, M.A., S.O. Adeosun and O.R. Ilesanmi, 2007. Neuropharmacological effects of Oleamide in male and female mice. Behav. Brain Res., 182: 88-89.
9. Al-Naggar, T.B., M.P. Gomez-Serranillos, M.E. Carretero and A.M. Villar, 2003. Neuropharmacological activity of Nigella sativa L. extracts. J. Ethnopharmacol., 88: 63-68.
10. Aladesanmi, J. A., 2007. Tetrapleura tetraptera. Molluscicidal activity and chemical constituents: A review. Afr. J. Trad. Complementary Alternative Med., 4: 23-36.
11. Amoo, S.O., A.U. Ojo and J. van Staden, 2008. Allelpathic potential of Tetrapleura tetraptera leaf extracts on early seedling of five agricultural crops. South Afr. J. Bot., 74: 149-152.
12. Ansah, C., E. Woode, E.A.A. Mfoafo and M. Duwiejua, 2008. Anxiogenic effect of an aqueous extract of Cryptolepis sanquinolenta. Int. J. Pharmacol., 4: 20-26.
13. Ayoka, A.O., R.O. Akomolafe, E.O. Iwalewa, M.A. Akanmu and O.E. Ukponwan, 2006. Sedative antiepileptic and antipsychotic effects of Spondia mombin L. (Anacardiaceae) in mice and rats. J. Ethnopharmacol., 103: 166-175.
14. Castro, C. A., J.B. Hogan, K. A. Benson, C. W. Shehata and M.R. Landauer, 1995. Behavioural effects of vehicles: DMSO, ethanol, Tween-20, Tween-80 and emulphor-620. Pharmacol. Biochem. Behav., 50: 521-526.
15. Chattopadhyay, D., G. Arunachalam, S.C. Mandal, R. Bhadra and A.B Mandal, 2003. CNS activity of the methanol extract of malloatus (Geist) muell arg. leaf: An ethnomedicine of onge. J. Ethnopharmacol., 85: 99-105.
16. Dorr, M., D. Jayce, R.D. Porsolt, H. Steinberg, A. Summerfield andN. Tomkiewicz, 1971. Persistence of dose related behavior in mice. Nature, 231: 121-123.
17. El-Izzi, A., T. Bennie, M. Thieulant and L. Dural, 1990. Inhibitory effect of Saponins from Tetrapleura tetraptera on the luteinizing hormone release by pituitary cells. PlantaMed., 56: 357-359.
18. Essien, E.U., B.C. Izunwane, C.Y. Aremu and O.U. Eka, 1994. Significance for human of the nutrients of the dry fruits of Tetrapleura tetraptera. Plant Foods Hum. Nutr., 45: 47-51.
19. Garrett, K.M., G. Basnadjian, I.A. Khan, B.T. Shaneberg and T.W. Scale, 2003. Extract of Kava (Piper methysticum) induce acute anxiolytic like behaviour in mice. Psychopharmacology, 170: 33-41.
20. Glantz, A.S., 1992. Primer of Biostatistics. Version 3.01, McGraw-Hill Inc., USA.
21. Gottesmann, C., 2002. GABA mechanism and sleep. Neuroscience, 111: 231-239.
22. Kumar, R.S., R.S. Sundram, P. Sivakumar, R. Nethaji, V. Senthil, N.V. Murthy and R. Kanagasabi, 2008. CNS activity of the methanol extracts of Careya arborea in experimental animal model. Bangladesh J. Pharmacol., 3: 36-43.
23. Labella, F.S., C. Punsky and V. Havlicek, 1979. Morphine derivatives with diminished opiate receptor potency show enhanced control excitatory activity. Brain Res., 174: 263-271.
24. Lawal, R.A., S.A. Ojokuku and S.O. Odesanmi, 2009. Effects of ethanolic extract of Tetrapleura tetraptera on liver function profile and histopathology in male dutch white rabbits. Int. J. Trop. Med., 4: 136-139.
25. Lichtfield, J.T. and F.A. Wilcoxon, 1949. A simplified method of evaluation doses-effects experiments J. Pharmacol. Exp. Ther., 96: 99-113.
26. Mandal, S.C., A.K. Dhara and B.C. Manti, 2001. Neuropharmacological activity of Xanthium strumarium Linn, extract. J. Herbs Spices Med. Plants, 8: 69-77.
27. Miller, L.C. andM.L. Tamter, 1944. Estimation of ED50 and its error by means of Logarithmic probit graph paper. Proc. Soc. Exp. Bio. Med., 57: 261-269.
28. Musa, A.M., A.H. Yaro and N.M. Danjuma, 2006. Preliminary phytochemical screening and central nervous system depressant activity of the stem bark of Ficus thoningn blums. Biol. Environ. Sci. Trop. J., 3: 1-6.
29. Musa, A.M., A.H. Yaro, H. Usman, M.G. Magaji and M. Habu, 2008. Phytochemical and some neuropharmacological studies on the methanolic leaf extracts of Cissus cornifolia [Vitaceae] in mice. Int. J. Pharmacol., 4: 145-148.
30. Noamesi, B.K., J.F. Mensah, M. Bogale, E. Dagney and J. Adotey, 1994. Antiulcerative properties and acute toxicity profile of some African medicinal plants extracts. J. Ethnopharmacol., 42: 13-18.
31. Nwawu, J.I. and P. A. Akali, 1986. Anticonvulsant activity of the volatile oil from the fruit of Tetrapleura tetraptera. J. Ethnopharmacol., 18: 103-107.
32. Ojewole, J.A.O. and S.K. Adesina, 1983. Mchanism of the hypotensive effect of Scopoletin isolated from the fruit of rapleura tetraptera. Planta Med., 49: 46-50.
33. Ojewole, J.A.O. and C.O. Adewunmi, 2004. And inflammatoiy and hypoglycaemic effects of Tetrapleura tetraptera (Taub.) (Fabaceae) fruit aqueous extract in rats. J. Ethnopharmacol., 95: 177-182.
34. Ojewole, J.A.O., 2005. Analgesic and anticonvulsant properties of Tetrapleura tetrapetra (Taub) [Fabaceae] fruit aqueous extract in mice. Phytother. Res., 19: 1023-1029.
35. Okonkon, J.E., A.E. Udokpoh and B.S. Antia, 2007. Antimalaria activity of ethanolic extract of Tetrapleura tetraptera fruit. J. Ethnopharmacol., 111: 537-540.
36. Okwu, D.E., 2003. The potentials of Ocimum gratissimum, Pergularia externa and Tetrapleura tetraptera as spice and flavouring agents. Nig. Agric. J., 35: 143-148.
37. Onaivi, E.S., P.A. Maguiri, N.F. Tsai, M.F. Davies and G.H. Locu, 1992. Comparison of behavioural and central BDZ binding profile in three rat lines. Pharmacol. Biochem. Behav., 43: 825-831.
38. Rabbani, M., S.E. Sajjadi andH.R. Zarett, 2003. Anxiolytic effect of Stachys lavandulifolia Vahl on the elevated plus maze model of anxiety in mice. J. Ethnopharmacol., 89: 271-276.
39. Rang, H.P., M.M. Dale and J.M. Ritter, 1999. Pharmacology. 3rd Edn., Churchill Livingstone, USA., pp: 491-665.
40. Steckler, T., W.H. Drunkenburg, H. Sahgal and J.P. Aggleton, 1998. Recognition memory inrats-1. Concepts and classification. Prog. Neurobiol., 54: 289-311.
41. Viswanatha Swamy, A.H.M., A.H.M. Thippeswamy, D. V. Manjula and C.B. Mehendra Kumar, 2006. Some neuropharmacological effects of the methanolic root extract of Cissus quadrangularis in mice. Afr. J. Biomed. Res., 9: 69-75.
42. Waiting, K.J., 1998. Overview of Central Nervous System Receptors. In: The RBI Handbook of Receptor Classification and Signal Transduction. Waiting, K.J. (Ed.). 3rd Edn., RBI,Natick, MA, pp: 2-45.