Quantification of leukocyte genomic 5-methylcytosine levels reveals epigenetic plasticity in healthy adult cloned cattle

Cellular Reprogramming

Volumn 12, Issue 2, 2010, Pages 175-181

  De Montera, Béatrice ^a   El Zeihery, Dalia ^b   Müller, Sigrid ^c   Jammes, Hélène ^a   Brem, Gottfried ^d   Reichenbach, Horst Dieter ^e   Scheipl, Fabian ^c   Chavatte Palmer, Pascale ^a   Zakhartchenko, Valeri ^c   Schmitz, Oliver J ^b   Wolf, Eckhard ^c   Renard, Jean Paul ^a   Hiendleder, Stefan ^c,f,g  

^a INRA Institut National de la Recherche Agronomique   (France)

^b UNIVERSITY OF WUPPERTAL   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^e Bayerische Landesanstalt für Landwirtschaft ^*  (Germany)

^f UNIVERSITY OF ADELAIDE   (Australia)

^g UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLCYTOSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREEDING; CAPILLARY ELECTROPHORESIS; CATTLE; CELL CLONING; CELL NUCLEUS TRANSPLANTATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; FEMALE; GENOTYPE; LEUKOCYTE; MONOZYGOTIC TWINS; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; SOMATIC CELL;

5-METHYLCYTOSINE; ANIMALS; CELL DIVISION; CELL LINEAGE; CLONING, ORGANISM; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; LEUKOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SKIN; STEM CELLS; SWINE; TRANSFORMING GROWTH FACTOR BETA;

BOS; BOVINAE;

EID: 77955597996     PISSN: 21524971     EISSN: 21524998     Source Type: Journal    
DOI: 10.1089/cell.2009.0062     Document Type: Article

References (46)

1. Axume, J., Smith, S.S., Pogribny, I.P., et al. (2007). Global leukocyte DNA methylation is similar in African American and Caucasian women under conditions of controlled folate intake. Epigenetics 2, 66-68. (Pubitemid 46824851)
2. Bates, D. (2009). lme4: linear mixed-effects models using S4 classes. R package version 0.999375-31.
3. Bernstein, B.E., Meissner, A., and Lander, E.S. (2007). The mammalian epigenome. Cell 128, 669-681
4. Bourc'his, D., Le Bourhis, D., Patin, D., et al. (2001). Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos. Curr. Biol. 11, 1542-1546.
5. Campbell, K. (1999). Nuclear transfer in farm animal species. Semin. Cell Dev. Biol. 10, 245-252.
6. Chavatte-Palmer, P., Heyman, Y., Richard, C., et al. (2002). Clinical, hormonal and hematologic characteristics of bovine calves derived from nuclei from somatic cells. Biol. Reprod. 66, 1593-1603.
7. Dean, W., Santos, F., Stojkovic, M., et al. (2001). Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos. Proc. Natl. Acad. Sci. USA 98, 13734-13738.
8. Fauque, P., Jouannet, P., Lesaffre, C., et al. (2009). Assisted reproductive technology affects developmental kinetics, H19 imprinting control region methylation and H19 gene expression in individual mouse embryos. BMC Dev. Biol. 7, 116-134.
9. Fox, J.L. (2008). Cloned animals deemed safe to eat, but labelling issues loom. Nat. Biotechnol. 26, 249-250.
10. Fraga, M.F., Ballestar, E., Paz, M.F., et al. (2005). Epigenetic differences arise during the lifetime of monozygotic twins. Proc. Natl. Acad. Sci. USA 102, 10604-10609.
11. Hiendleder, S., Mund, C., Reichenbach, H.D., et al. (2004). Tissue-specific elevated genomic cytosine methylation levels are associated with an overgrowth phenotype of bovine fetuses derived by in vitro techniques. Biol. Reprod. 71, 217-223.
12. Humpherys, D., Eggan, K., Akutsu, H., et al. (2001). Epigenetic instability in ES cells and cloned mice. Science 293, 95-97.
13. Jaenisch, R., and Wilmut, I. (2001). Developmental biology: don't clone humans! Science 291, 2552.
14. Johannes, F., Colot, V., and Jansen, R.C. (2008). Epigenome dynamics: a quantitative genetics perspective. Nat. Rev. Genet. 9, 883-890.
15. Kaminsky, Z.A., Tang, T., Wang, S.C., et al. (2009). DNA methylation profiles in monozygotic and dizygotic twins. Nat. Genet. 41, 240-245.
16. Keefer, C.L. (2008). Lessons learned from nuclear transfer (cloning). Theriogenology 69, 48-54.
17. Klein, C., Bauersachs, S., Ulbrich, S.E., et al. (2006). Monozygotic twin model reveals novel embryo-induced transcriptome changes of bovine endometrium in the preattachment period. Biol. Reprod. 74, 253-264.
18. Lanza, R.P., Cibelli, J.B., Faber, D., et al. (2001). Cloned cattle can be healthy and normal. Science 294, 1893-1894.
19. Lin, L., Li, Q., Zhang, L., et al. (2008). Aberrant epigenetic changes and gene expression in cloned cattle dying around birth. BMC Dev. Biol. 8, 14-23.
20. Liu, J.H., Yin, S., Xiong, B., et al. (2008). Aberrant DNA meth-ylation imprints in aborted bovine clones. Mol. Reprod. Dev. 75, 598-607.
21. Long, J.E., and Cai, X. (2007). Igf-2r expression regulated by epigenetic modification and the locus of gene imprinting disrupted in cloned cattle. Gene 388, 125-134.
22. Luedi, P.P., Hartemink, A.J., and Jirtle, R.L. (2005). Genome-wide prediction of imprinted murine genes. Genome Res. 15, 875-884.
23. Morgan, H.D., Santos, F., Green, K., et al. (2005). Epigenetic re-programming in mammals. Hum. Mol. Genet. 14(Spec. No. 1), R47-R58.
24. Niemann, H., Tian, X.C., King, W.A., et al. (2008). Epigenetic re-programming in embryonic and foetal development upon somatic cell nuclear transfer cloning. Reproduction 135, 151-163.
25. Ohgane, J., Wakayama, T., Kogo, Y., et al. (2001). DNA meth-ylation variation in cloned mice. Genesis 30, 45-50.
26. Ohgane, J., Wakayama. T., Senda, S., et al. (2004). The Sall3 locus is an epigenetic hotspot of aberrant DNA methylation associated with placentomegaly of cloned mice. Genes Cells 9, 253-260.
27. Pinheiro, J., and Bates, D. (2000). Mixed-Effects Models in S and S-Plus. (Springer, Berlin).
28. R Development Core Team. (2008). R: A Language and Environment for Statistical Computing (R Foundation for Statistical Computing, Vienna, Austria). Available at: http:== www.R-project.org
29. Reik, W. (2007). Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447, 425-432.
30. Rhind, S.M., King, T.J., Harkness, L.M., et al. (2003a). Cloned lambs-lessons from pathology. Nat. Biotechnol. 21, 744-745.
31. Rhind, S.M., Taylor, J.E., De Sousa, P.A., et al. (2003b). Human cloning: can it be made safe? Nat. Rev. Genet. 4, 855-864.
32. Richards, E.J. (2006). Inherited epigenetic variation\revisiting soft inheritance. Nat. Rev. Genet. 7, 395-401.
33. Robertson, K.D. (2005). DNA methylation and human disease. Nat. Rev. Genet. 6, 597-610.
34. Santos, F., Zakhartchenko, V., Stojkovic, M., et al. (2003). Epige-netic marking correlates with developmental potential in cloned bovine preimplantation embryos. Curr. Biol. 13, 1116-1121.
35. Scheipl, F. (2007). RLRsim: restricted likelihood ratio tests in linear mixed models. R package version 2007, 1.0.
36. Scheipl, F., Greven, S., and Kü chenhoff, H. (2008). Size and power of tests for a zero random effect variance or polynomial regression in additive and linear mixed models. Comput. Stat. Data Anal. 52, 3283-3299.
37. Schmitz, O.J., Wörth, C.C.T., Stach, D., et al. (2002). Capillary electrophoresis analysis of DNA adducts as biomarkers for carcinogenesis. Angew. Chem. Int. Ed. 41, 445-448.
38. Senda, S., Wakayama, T., Arai, Y., et al. (2007). DNA methyla-tion errors in cloned mice disappear with advancement of aging. Cloning Stem Cells 9, 293-302.
39. Stach, D., Schmitz, O.J., Stilgenbauer, S., et al. (2003). Capillary electrophoretic analysis of genomic DNA methylation levels. Nucleic Acids Res. 31, e2.
40. Vignon, X., Chesné, P., Le Bourhis, D., et al. (1998). Developmental potential of bovine embryos reconstructed from enucleated matured oocytes fused with cultured somatic cells. C.R. Acad. Sci. Paris 321, 735-745.
41. Wells, D.N., Forsyth, J.T., McMillan, V., et al. (2004). The health of somatic cell cloned cattle and their offspring. Cloning Stem Cells 6, 101-110.
42. Wilmut, I. (2006). Are there any normal clones? Methods Mol. Biol. 348, 307-318.
43. Yang, X., Smith, S.L., Tian, X.C., et al. (2007a). Nuclear repro-gramming of cloned embryos and its implications for therapeutic cloning. Nat. Genet. 39, 295-302. (Pubitemid 46328492)
44. Yang, X., Tian, X.C., Kubota, C., et al. (2007b). Assessment of meat and milk from cloned animals. Nat. Biotechnol. 25, 77-83.
45. Yang, J., Yang, S., Beaujean, N., et al. (2007c). Epigenetic marks in cloned rhesus monkey embryos: comparison with counterparts produced in vitro. Biol. Reprod. 76, 36-42.
46. Zakhartchenko, V., Durcova-Hills, G., Stojkovic, M., et al. (1999). Effects of serum starvation and re-cloning on the efficiency of nuclear transfer using bovine fetal fibroblasts. J. Reprod. Fertil. 115, 325-331.