Clobazam in refractory childhood epilepsy

Indian Journal of Pediatrics

Volumn 77, Issue 3, 2010, Pages 263-266

  Kalra, Veena ^a   Seth, Rachna ^a   Mishra, Devendra ^a   Saha, Narayan C ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Add on therapy; Clobazam; Newer antiepileptics; Refractory epilepsy

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CLOBAZAM; PHENOBARBITAL; PHENYTOIN; VALPROIC ACID;

ADD ON THERAPY; ARTICLE; ATAXIA; BEHAVIOR DISORDER; BENIGN CHILDHOOD EPILEPSY; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE CONTROL; DISEASE SEVERITY; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; EPILEPSY; FATIGUE; FEMALE; HUMAN; HYPERACTIVITY; INDIAN; INFANT; IRRITABILITY; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; REFRACTORY PERIOD; SALIVATION; SCHOOL CHILD; SEDATION; SIDE EFFECT; SLEEP DISORDER; TONIC CLONIC SEIZURE; TREATMENT DURATION; TREATMENT RESPONSE; WEIGHT GAIN;

ANTICONVULSANTS; BENZODIAZEPINES; CHILD; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; HUMANS; MALE; PROSPECTIVE STUDIES;

EID: 77955579011     PISSN: 00195456     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12098-010-0035-z     Document Type: Article

References (18)

1. Sugai K. Clobazam as a new anti epileptic drug and clorazepate dipotassium as an alternative antiepileptic drug in Japan. Epilepsia 2004; 45 Suppl 8: 20-25.
2. Keene DL, Whiting S, Humphreys P. Clobazam as an addon drug in the treatmet of refractory epilepsy of childhood. Can J Neurol Sci 1990; 17: 317-319.
3. Shimizu H, Kawasaki J, Yuasa S, Tarao Y, Kumagai S, Kanemoto K. Use of clobazam for the treatment of refractory complex partial seizures. Seizure 2003; 12: 282-286.
4. Bawden HN, Camfield CS, Camfield PR, et al. The cognitive and behavioural effects of clobazam and standard monotherapy are comparable. Canadian Study Group for Childhood Epilepsy. Epilepsy Res 1999; 33: 133-143.
5. Canadian Clobazam Cooperative Group. Clobazam in treatment of refractory epilepsy: The Canadian Experience. A retrospective study. Epilepsia 1991; 32: 407-416.
6. Theis JG, Koren G, Daneman R et al. Interactions of clobazam with conventional antiepileptics in children. J Child Neurol 1997; 12: 208-213.
7. Satishchandra P, Varadarajalu R, Rajaram P. Long term use of Clobazam in the management of intractable epilepsy. Neurol India 1998; 46: 284-287.
8. Mehndiratta MM, Krishnamurthy M, Rajesh KN, Singh G. Clobazam monotherapy in drug naive adult patients with epilepsy. Seizure 2003; 12: 226-228.
9. Kalra V, Seth R, Mishra D, Saha NC. Add on Clobazam in resistant childhood epilepsy-Adverse drug reaction study. Indian J Pediatr 2004; SS-1: 102.
10. Eypasch E, Lefering R, Kum CK, Troidl H. Probability of adverse events that have not yet occurred: a statistical reminder. BMJ 1995; 311: 619-620.
11. Shimizu H, Abe J, Futagi Y, et al. Antieileptic effects of clobazam in children. Brain Dev 1982; 4: 57-62.
12. Munn, Campfield P, Campfield C, Dooley J. Clobazam for refractory childhood seizure disorders-a valuable supplementary drug. Can J Neurol Sci 1988; 15: 406-408.
13. Canadian Study Group for Childhood Epilepsy. Clobazam has equivalent efficacy to carbamazepine and phenytoin as monotherapy for childhood epilepsy. Epilepsia 1998; 39: 952-959.
14. Munn R, Farrell K. Open study of clobazam in refractory epilepsy. Pediatr Neurol 1993; 9: 465-469.
15. Montenegro MA, Cendes F, Noronha AL et al. Efficacy of clobazam as add on therapy in patients with refractory partial epilepsy. Epilepsia 2001; 42: 539-542.
16. Sheth RD, Ronen GM, Goulden KJ, Penney S, Bodensteiner JB. Clobazam for intractable pediatric epilepsy. J Child Neurol 1995; 10: 205-208.
17. Jan MM, Shaabat AO. Clobazam for the treatment of intractable childhood epilepsy. Saudi Med J 2000; 21: 622-624.
18. Barcs G, Halasz P. Effectiveness and tolerance of clobazam in temporal lobe epilepsy. Acta Neurol Scand 1996; 93: 88-93.