Polysaccharide pharmacokinetics: Amphotericin B arabinogalactan conjugate-A drug delivery system or a new pharmaceutical entity?

Biomacromolecules

Volumn 11, Issue 8, 2010, Pages 1972-1977

  Elgart, Anna ^a   Farber, Shimon ^a   Domb, Abraham J ^a   Polacheck, Itzhack ^b   Hoffman, Amnon ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANTI-FUNGAL ACTIVITY; ARABINOGALACTAN; DRUG DELIVERY SYSTEM; HALF LIVES; IMPROVED SOLUBILITY; LOW MOLECULAR WEIGHT; POORLY SOLUBLE DRUGS; PRODRUGS; REDUCED TOXICITY; SMALL MOLECULES;

DRUG DELIVERY; MOLECULAR WEIGHT; PHARMACOKINETICS; POLYSACCHARIDES; SOLUBILITY;

DRUG PRODUCTS;

AMPHOTERICIN B ARABINOGALACTAN CONJUGATE; AMPHOTERICIN B DEOXYCHOLATE; ARABINOGALACTAN; POLYSACCHARIDE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIFUNGAL ACTIVITY; ARTICLE; BLOOD SAMPLING; CONJUGATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MACROMOLECULE; MALE; MOLECULAR WEIGHT; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT;

AMPHOTERICIN B; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DELIVERY SYSTEMS; GALACTANS; HALF-LIFE; MALE; POLYSACCHARIDES; RATS; RATS, WISTAR; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

RATTUS;

EID: 77955563140     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm100298r     Document Type: Article

References (31)

1. Allen, T. M.; Cullis, P. R. Science 2004, 303, 1818-1822
2. Veronese, F. M.; Morpurgo, M. Farmaco 1999, 54, 497-516
3. Mehvar, R. Curr. Pharm. Biotechnol. 2003, 4, 283-302
4. Fuertges, F.; Abuchowski, A. J. Controlled Release 1990, 11, 139-148
5. Vasey, P. A.; Kaye, S. B.; Morrison, R.; Twelves, C.; Wilson, P.; Duncan, R.; Thomson, A. H.; Murray, L. S.; Hilditch, T. E.; Murray, T.; Burtles, S.; Fraier, D.; Frigerio, E.; Cassidy, J. Clin. Cancer Res. 1999, 5, 83-94
6. Vercauteren, R.; Bruneel, D.; Schacht, E.; Duncan, R. J. Bioact. Compat. Polym. 1990, 5, 4-15
7. Hreczuk-Hirst, D.; Chicco, D.; German, L.; Duncan, R. Int. J. Pharm. 2001, 230, 57-66
8. Falk, R.; Domb, A. J.; Polacheck, I. Antimicrob. Agents Chemother. 1999, 43, 1975-81
9. Dupont, B. J. Antimicrob. Chemother. 2002, 49, 31-6
10. Milhaud, J.; Ponsinet, V.; Takashi, M.; Michels, B. Biochim. Biophys. Acta 2002, 1558, 95-108
11. Deray, G. J. Antimicrob. Chemother. 2002, 49, 37-41
12. Storm, G.; van Etten, E. Eur. J. Clin. Microbiol. Infect. Dis. 1997, 16, 64-73
13. Boswell, G. W.; Bekersky, I.; Buell, D.; Hiles, R.; Walsh, T. J. Antimicrob. Agents Chemother. 1998, 42, 263-8
14. Nath, C. E.; Shaw, P. J.; Gunning, R.; Mclachlan, A. J.; Earl, J. W. Antimicrob. Agents Chemother. 1999, 43, 1417-23
15. Kuti, J. L.; Kotapati, S.; Williams, P.; Capitano, B.; Nightingale, C. H.; Nicolau, D. P. Pharmacoeconomics 2004, 22, 301-10
16. Ehrenfreund-Kleinman, T.; Azzam, T.; Falk, R.; Polacheck, I.; Golenser, J.; Domb, A. J. Biomaterials 2002, 23, 1327-35
17. Golenser, J.; Frankenburg, S.; Ehrenfreund, T.; Domb, A. J. Antimicrob. Agents Chemother. 1999, 43, 2209-14
18. Falk, R.; Grunwald, J.; Hoffman, A.; Domb, A. J.; Polacheck, I. Antimicrob. Agents Chemother. 2004, 48, 3606-9
19. Chow, H. H.; Cai, Y.; Mayersohn, M. Drug Metab. Dispos. 1992, 20, 432-5
20. Chabot, G. G.; Pazdur, R.; Valeriote, F. A.; Baker, L. H. J. Pharm. Sci. 1989, 78, 307-10
21. Wasan, K. M.; Vadiei, K.; Lopez-Berestein, G.; Luke, D. R. J. Infect. Dis. 1990, 161, 562-6
22. Wang, L. H.; Fielding, R. M.; Smith, P. C.; Guo, L. S. Pharm. Res. 1995, 12, 275-83
23. Chow, H. H.; Wu, Y.; Mayersohn, M. Biopharm. Drug Dispos. 1995, 16, 461-73
24. Fielding, R. M.; Smith, P. C.; Wang, L. H.; Porter, J.; Guo, L. S. Antimicrob. Agents Chemother. 1991, 35, 1208-13
25. Vadiei, K.; Lopez-Berestein, G.; Luke, D. R. Int. J. Obes. 1990, 14, 465-72
26. Kim, H.; Loebenberg, D.; Marco, A.; Symchowicz, S.; Lin, C. Antimicrob. Agents Chemother. 1984, 26, 446-9
27. Mehvar, R.; Shepard, T. L. J. Pharm. Sci. 1992, 81, 908-12
28. Kaneo, Y.; Ueno, T.; Tanaka, T.; Iwase, H.; Yamaguchi, Y.; Uemura, T. Int. J. Pharm. 2000, 201, 59-69
29. Zhang, X.; Mehvar, R. J. Pharm. Sci. 2001, 90, 2078-87
30. Lemke, A.; Kiderlen, A. F.; Kayser, O. Appl. Microbiol. Biotechnol. 2005, 68, 151-62
31. Surarit, R.; Shepherd, M. G. J. Med. Vet. Mycol. 1987, 25, 403-13