Tissue oxygen tension profiles close to brain arterioles and venules in the rat cerebral cortex during the development of acute anemia

Neuroscience and Behavioral Physiology

Volumn 40, Issue 7, 2010, Pages 723-731

  Vovenko, E P ^a   Chuikin, A E ^a  

^a PAVLOV INSTITUTE OF PHYSIOLOGY   (Russian Federation)

Author keywords

acute normovolemic hemodilution; anemia; arterioles; hypoxia; oxygen microelectrodes; oxygen tension; pO2 gradients; pO2 profiles; venules

Indexed keywords

HEMOGLOBIN; OXYGEN;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BLOOD VESSEL DIAMETER; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN CAPILLARY; BRAIN CORTEX; CONTROLLED STUDY; HEMODILUTION; HEMOGLOBIN BLOOD LEVEL; HYPOXEMIA; MALE; NONHUMAN; OXYGEN TISSUE LEVEL; PATHOPHYSIOLOGY; RAT; VENULE;

ACUTE DISEASE; ANEMIA; ANIMALS; ANOXIA; ARTERIOLES; CEREBRAL CORTEX; CEREBROVASCULAR CIRCULATION; HEMOGLOBINS; MALE; MICROCIRCULATION; OXYGEN; OXYGEN CONSUMPTION; RATS; RATS, WISTAR; VENULES;

EID: 77955560162     PISSN: 00970549     EISSN: 1573899X     Source Type: Journal    
DOI: 10.1007/s11055-010-9318-0     Document Type: Article

References (47)

1. EP Vovenko AE Chuikin 2007 Oxygen tension in rat cerebral cortex microvessels in acute ischemia Ros. Fiziol. Zh. im. I. M. Sechenova 93 6 643 654
2. EP Vovenko 1997 Quantitative characteristics of the distribution of oxygen tension in rat cerebral cortex arterioles and venules in normoxemia Ros. Fiziol. Zh. im. I. M. Sechenova 83 4 77 85
3. EP Vovenko 2008 Oxygen microelectrodes for physiological studies Region. Krovoobrashch. Mikrotsirk. 7 1 64 71
4. KP Ivanov EP Vovenko 1986 The specific characteristics of tissue oxygen supply from arterioles and capillaries Dokl. Akad. Nauk SSSR 286 1 227 229 3948671
5. KP Ivanov AE Chuikin OV Berkos AL Stolbov 1983 The physiological mechanisms of meeting the body's energy needs in conditions of decreased blood hemoglobin concentrations Fiziol. Zh. SSSR 69 7 942 948 6680356
6. KP Ivanov AN Derii MO Samoilov DG Semenov 1979 Diffusion of oxygen from the smallest arterioles in the brain Dokl. Akad. Nauk SSSR 244 6 1509 1511 428311
7. AL Stolbov 1983 Changes in oxygen tension in the cerebral cortex in hemodilution Byull. Eksperim. Biol. Med. 96 9 18 20
8. L Borgstrom H Johannsson BK Siesjo 1975 The influence of acute normovolemic anemia on cerebral blood flow and oxygen consumption of anesthetized rats Acta Physiol. Scand. 93 4 505 514 10.1111/j.1748-1716.1975. tb05842.x 1155144
9. R Chan E Leniger-Follert 1983 Effect of isovolemic hemodilution on oxygen supply and electrocorticogram in cat brain during focal ischemia and in normal tissue Int. J. Microcirc. Clin. Exp. 2 4 297 313 6206009
10. BL Chang T Yamakawa J Nuccio R Pace RJ Bing 1982 Microcirculation of left atrial muscle, cerebral cortex and mesentery of the cat. A comparative analysis Circ. Res. 50 2 240 249 7055858
11. FC Fan RY Chen GB Schuessler S Chien 1980 Effects of hematocrit variations on regional hemodynamics and oxygen transport in the dog Am. J. Physiol. 238 4 H545 622 7377327
12. GM Hare 2004 Anaemia and the brain Curr. Opin. Anesthesiol. 17 5 363 369 10.1097/00001503-200410000-00003 (Pubitemid 39331941)
13. GM Hare AK Tsui AT McLaren TE Ragoonanan J Yu SB Mazer 2008 Anemia and cerebral outcomes: many questions, fewer answers Anesthesiol. Analg. 107 4 1356 1370 10.1213/ane.0b013e318184cfe9
14. R Hlatky AB Valadka JC Goodman CF Contant CS Robertson 2004 Patterns of energy substrates during ischemia measured in the brain by microdialysis J. Neurotrauma 21 7 894 906 10.1089/0897715041526195 15307902 (Pubitemid 38998917)
15. AG Hudetz JD Wood BB Biswal I Krolo JP Kampine 1999 Effect of hemodilution on RBC velocity, supply rate, and hematocrit in the cerebral capillary network J. Appl. Physiol. 87 2 505 509 10444605
16. DB Hughes BW Ullery PS Barie 2008 The contemporary approach to the care of Jehovah's witnesses J. Trauma 65 1 237 247 10.1097/TA.0b013e318176cc66 18580506
17. KP Ivanov AN Derry EP Vovenko MO Samoilov DG Semionov 1982 Direct measurements of oxygen tension at the surface of arterioles, capillaries and venules of the cerebral cortex Pflügers Arch. 393 1 118 120 10.1007/BF00582403 7088679
18. J Johannsson BK Siesjo 1974 Blood flow and oxygen consumption in the rat brain in dilutional anemia Acta Physiol. Scand. 91 1 136 138 10.1111/j.1748-1716.1974.tb05667.x 4835719
19. K Karadibak N Gokmen S Erbayraktar Y Goktay A Taplu A Arkan N Erkan 2002 Effects of normovolaemic haemodilution on middle cerebral artery blood flow velocity and oxygen delivery Eur. J. Anaesthesiol. 19 5 330 336 12095012
20. 2 Brit. J. Neurosurg. 17 4 311 318 10.1080/02688690310001601199 (Pubitemid 37243961)
21. KL Kiening AW Unterberg TF Bardt GH Schneider WR Lanksch 1996 Monitoring of cerebral oxygenation in patients with severe head injuries: brain tissue pO2 versus jugular vein oxygen saturation J. Neurosurg. 85 5 751 757 10.3171/jns.1996.85.5.0751 8893710
22. T Krantz J Warberg NH Secher 2005 Venous oxygen saturation during normovolaemic haemodilution in the pig Acta Anaesthesiol. Scand. 49 8 1149 1156 10.1111/j.1399-6576.2005.00778.x 16095457 (Pubitemid 41192464)
23. PS Levy SJ Kim PK Eckel R Chavez EF Ismail SA Gould SM Ramez GJ Crystal 1993 Limit to cardiac compensation during acute isovolemic hemodilution: influence of coronary stenosis Am. J. Physiol. 256 1 H340 H349
24. M Li S Ratcliffe F Knoll J Wu B Ances W Mardini TF Floyd 2006 Aging: impact upon local cerebral oxygenation and blood flow with acute isovolemic hemodilution J. Neurosurg. Anaesthesiol. 18 2 125 131 10.1097/00008506- 200604000-00006 (Pubitemid 44510111)
25. D. W. Lubbers, "The oxygen pressure field in the brain and its significance for the normal and critical oxygen supply of the brain," 67-92 (1968).
26. G. I. Mchedlishvili, "Cerebral arterial behaviour providing constant cerebral blood flow, pressure and volume," in: Arterial Behaviour and Blood Circulation in the Brain (1986), pp. 42-95.
27. LA McIntyre DA Ferguson JS Hitchinson G Pagliarello J Marshall E Yetisir GM Hare PC Hebert 2006 Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury Neurocrit. Care 5 1 4 9 10.1385/NCC:5:1:4 16960287 (Pubitemid 44379144)
28. K Messmer L Sunder-Plassmann F Jesch L Gornandt E Sinagowitz M Kessler 1973 Oxygen supply to the tissues during limited normovolemic hemodilution Res. Exp. Med. (Berl.) 159 152 166 10.1007/BF01851543
29. Y Morimoto M Mathru J Martinez-Tica MH Zornow 2001 Effects of profound anemia on brain tissue oxygen tension, carbon dioxide tension, and pH in rabbits J. Neurosurg. Anaesthesiol. 13 1 33 39 10.1097/00008506-200101000-00006 (Pubitemid 32104099)
30. M. Oddo, A. Milby, I. Chen, S. Frangos, E. Macmurtrie, E. Maloney-Wilensky, M. Stiefel, W. A. Kofke, J. M. Levine, and P. D. Le Roux, "Hemoglobin concentration and cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage," Stroke, DOI: 10.1161/STROKEAHA.108. 527911 (2009).
31. G Pawlik A Rackl RJ Bing 1981 Quantitative capillary topography and blood flow in the cerebral cortex of cats: an in vivo microscopic study Brain Res. 208 1 35 58 10.1016/0006-8993(81)90619-3 7470927 (Pubitemid 11130288)
32. A Rebel C Lenz H Krieter KF Waschke K van Ackern W Kuschinsky 2001 Oxygen delivery at high blood viscosity and decreased arterial oxygen content to brains of conscious rats Am. J. Physiol. Heart Circ. Physiol. 280 6 H2591 H2597 11356614
33. B Rosberg K Wulff 1979 Regional blood flow in normovolaemic and hypovolaemic haemodilution. An experimental study Brit. J. Anaesthesiol. 51 5 423 430 10.1093/bja/51.5.423
34. AS Sarrafzadeh OW Sakowitz TA Callsen WR Lanksch AW Unterberg 2000 Bedside microdialysis for early detection of cerebral hypoxia in traumatic brain injury Neurosurg. Focus 9 5 E2 10.3171/foc.2000.9.5.2 16821754
35. S Schmidt F Sierra H Fahnenstich K Beckmann D Krebs K Hultquist J Sussmane P Rolfe 1996 Cerebral tissue oxygenation during hypoxia and hyperoxia using artificial placentation in lamb J. Perinat. Med. 24 1 61 68 10.1515/jpme.1996.24.1.61 8708932
36. M Sharan EP Vovenko A Vadapalli AS Popel RN Pittman 2008 Experimental and theoretical studies of oxygen gradients in rat pial microvessels J. Cereb. Blood Flow Metab. 28 9 1597 1604 10.1038/jcbfm.2008.51 18506196
37. T Sinozuka EM Nemoto PM Winter 1987 Cerebral cortical oxygenation and perfusion during progressive normovolaemic haemodilution with hetastarch (Volex) and fluosol-DA Adv. Exp. Med. Biol. 215 109 115
38. B. K. Siesjo, Brain Energy Metabolism, John Wiley & Sons Ltd., Chichester (1978).
39. MM Todd B Wu M Maktabi BJ Hindman DS Warner 1994 Cerebral blood flow and oxygen delivery during hypoxemia and hemodilution: role of arterial oxygen content Am. J. Physiol. 267 5 H2025 H2031 7977834
40. Y Tomiyama JE Brian Jr MM Todd 2000 Plasma viscosity and cerebral blood flow Am. J. Physiol. Heart Circ. Physiol. 279 4 H1949 H1954 11009484
41. Y Tomiyama K Jansen JE Brian Jr MM Todd 1999 Hemodilution, cerebral O2 delivery, and cerebral blood flow: a study using hyperbaric oxygenation Am. J. Physiol. 276 4 H1190 H1196 10199842
42. JA Ulatowski E Bucci A Razynska RJ Traystman RC Koehler 1998 Cerebral blood flow during hypoxic hypoxia with plasma-based hemoglobin at reduced hematocrit Am. J. Physiol. 274 6 H1933 H1942 9841479
43. EP Vovenko 1999 Distribution of oxygen tension on the surface of arterioles, capillaries and venules of brain cortex and in tissue in normoxia: an experimental study on rats Pflügers Arch. 437 4 617 623 10.1007/s004240050825 10089576 (Pubitemid 29110915)
44. 2 and blood velocity measurements in rat brain cortex during hemodilution with a plasma expander (Hespan) and a hemoglobin-based oxygen carrier (DCLHb) Adv. Exp. Med. Biol. 540 215 220 15174623
45. M Watanabe N Harada H Kosaka T Shiga 1994 Intravital microreflectometry of individual pial vessels and capillary region of rat J. Cereb. blood Flow Metab. 14 1 75 84 8263061
46. RB Weiskopf JH Kramer M Viele M Neumann JR Feiner JJ Watson HW Hopf P Toy 2000 Acute severe isovolemic anemia impairs cognitive function and memory in humans Anaesthesiology 92 6 1646 1652 10.1097/00000542-200006000-00023
47. R Zander 1993 Critical limits of hemodilution: theoretical principles Beitr. Infusionther. 29 51 69 7690662