Improved production of A40926 by Nonomuraea sp. through deletion of a pathway-specific acetyltransferase

Applied Microbiology and Biotechnology

Volumn 87, Issue 5, 2010, Pages 1633-1638

  Sosio, Margherita ^a,b   Canavesi, Augusto ^a,c   Stinchi, Sofia ^a   Donadio, Stefano ^a,b  

^a Vicuron Pharmaceuticals   (Italy)

^b Ktedogen Srl   (Italy)

^c Sicor Srl   (Italy)

Author keywords

Actinomycetes; Antibiotics; Glycopeptides

Indexed keywords

ACETYL RESIDUES; ACETYL TRANSFERASE; CLINICAL TRIAL; GENE CLUSTERS; GLYCOPEPTIDES; INHIBITORY EFFECT; MANNOSE MOIETY; MUTANT STRAIN; O-LINKED; PRODUCTION CULTURE; WILD TYPES; WILD-TYPE STRAIN;

ANTIBIOTICS; BIOCHEMISTRY; BIOSYNTHESIS;

PEPTIDES;

ACYLTRANSFERASE; DALBAVANCIN; GLYCOPEPTIDE; A 40926; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; TEICOPLANIN;

ANTIBIOTICS; BACTERIUM; ENZYME ACTIVITY; FERMENTATION; GENETIC ENGINEERING; INHIBITOR; MUTATION; PEPTIDE; SUGAR;

ACTINOBACTERIA; ARTICLE; BACTERIAL STRAIN; GENE CLUSTER; NONHUMAN; NONOMURAEA; SIGNAL TRANSDUCTION; ACTINOMYCETALES; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CHEMICAL STRUCTURE; ENZYMOLOGY; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MULTIGENE FAMILY;

ACETYLTRANSFERASES; ACTINOMYCETALES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MOLECULAR STRUCTURE; MULTIGENE FAMILY; SEQUENCE DELETION; TEICOPLANIN;

ACTINOBACTERIA (CLASS); NONOMURAEA;

EID: 77955559379     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-010-2579-2     Document Type: Article

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