Effect of glycyrrhizin on the activity of CYP3A enzyme in humans

European Journal of Clinical Pharmacology

Volumn 66, Issue 8, 2010, Pages 805-810

  Tu, Jiang Hua ^a   He, Yi Jing ^a   Chen, Yao ^a   Fan, Lan ^a   Zhang, Wei ^a   Tan, Zhi Rong ^a   Huang, Yuan Fei ^a   Guo, Dong ^a   Hu, Dong Li ^a   Wang, Dan ^a   Zhou, Hong Hao ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

CYP3A; Glycyrrhizin; Herb drug interaction; Induce; Licorice; Midazolam

Indexed keywords

CYTOCHROME P450 3A; GLYCYRRHIZIC ACID; MIDAZOLAM; MIDAZOLAM MALEATE; PLACEBO;

ABSENCE OF SIDE EFFECTS; ADULT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; BLOOD PRESSURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BLOOD LEVEL; DRUG METABOLISM; DRUG STRUCTURE; ENZYME ACTIVITY; EVENING DOSAGE; HUMAN; HUMAN EXPERIMENT; MALE; MORNING DOSAGE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; VOLUNTEER;

ADOLESCENT; ADULT; ANTI-INFLAMMATORY AGENTS; AREA UNDER CURVE; CROSS-OVER STUDIES; CYTOCHROME P-450 CYP3A; DOUBLE-BLIND METHOD; GLYCYRRHIZIC ACID; HALF-LIFE; HUMANS; MALE; METABOLIC CLEARANCE RATE; MIDAZOLAM; MOLECULAR STRUCTURE; THERAPEUTIC EQUIVALENCY;

EID: 77955549620     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-010-0814-5     Document Type: Article

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