Do hospital and community ssri usage patterns in children and adolescents match the evidence?

Journal of the Canadian Academy of Child and Adolescent Psychiatry

Volumn 19, Issue 3, 2010, Pages 218-226

  Ronsley, Rebecca ^a   Elbe, Dean ^b   Smith, Derryck H ^a   Garland, E Jane ^c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b CHILDREN S AND WOMEN S HEALTH CENTRE OF BRITISH COLUMBIA   (Canada)

^c BC CHILDREN S HOSPITAL   (Canada)

Author keywords

Adolescents; Anxiety; Children; Depression; Efficacy; Indications; Selective serotonin reuptake inhibitors

Indexed keywords

ATOMOXETINE; CITALOPRAM; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; PAROXETINE; PLACEBO; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; VENLAFAXINE;

ALCOHOLISM; ANXIETY DISORDER; ARTICLE; ATTENTION DEFICIT DISORDER; AUTISM; CANNABIS ADDICTION; CHILD PSYCHIATRY; CLINICAL TRIAL; COGNITIVE THERAPY; COMMUNITY CARE; CONTROLLED CLINICAL TRIAL; DEPRESSION; DRUG EFFICACY; DRUG UTILIZATION; EVIDENCE BASED MEDICINE; GENERALIZED ANXIETY DISORDER; HOSPITAL CARE; HOSPITAL PHARMACY; HUMAN; MEDICAL LITERATURE; MEDLINE; OBSESSIVE COMPULSIVE DISORDER; PEDIATRIC HOSPITAL; PRACTICE GUIDELINE; PRESCRIPTION; RANDOMIZED CONTROLLED TRIAL; SOCIAL PHOBIA;

EID: 77955545304     PISSN: 17198429     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Alaghband-Rad, J., & Hakimshooshtary, M. (2009). A randomized controlled clinical trial of citalopram versus fluoxetine in children and adolescents with obsessive-compulsive disorder (OCD). European Child and Adolescent Psychiatry, 18(3), 131-135
2. Bezchlibnyk-Butler Z., & Virani A. (2007). Clinical handbook of psychotropic drugs for children & adolescents. Second edition. Hogrefe & Huber; Cambridge, MA.
3. Berard, R., Fong, R., Carpenter, D. J., Thomason, C., & Wilkinson, C. (2006). An international, multicenter, placebo-controlled trial of paroxetine in adolescents with major depressive disorder. Journal of Child and Adolescent Psychopharmacology, 16(1), 59-75
4. Bhatia, S. K., Rezac, A. J., Vitiello, B., Sitorius, M. A., Buehler, B. A., & Kratochvil, C. J. (2008). Antidepressant prescribing practices for the treatment of children and adolescents. Journal of Child and Adolescent Psychopharmacology, 18(1), 70-80
5. Birmaher, B., Brent, D., Bernet, W., Bukstein, O., Walter, H., Benson, R. S., et al. (2007). Practice parameter for the assessment and treatment of children and adolescents with depressive disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 46(11), 1503-1526
6. Birmaher, B., Axelson, D. A., Monk, K., Kalas, C., Clark, D. B., Ehmann M., et al. (2003). Fluoxetine for the treatment of childhood anxiety disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 42(4), 415-423
7. Braconnier, A., Coent, R. L., & Cohen, D. (2003). Paroxetine versus clomipramine in adolescents with severe major depression: a double-blind, randomized, multicenter trial. Journal of the American Academy of Child and Adolescent Psychiatry, 42(1), 22-29
8. Brent, D., Emslie, G., Clarke, G., Wagner, K. D., Asarnow, J. R., Keller, M., et al. (2008). Switching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression. Journal of the American Medical Association, 299(8), 901-913
9. Cache Limited (2010). Oxford centre for evidence-based medicine-levels of evidence. Retrieved 04/23, 2010, from http://www.cebm.net/index.aspx?o=1025
10. Cheung, A. H., Emslie, G. J., & Mayes, T. L. (2005). Review of the efficacy and safety of antidepressants in youth depression. Journal of Child Psychology and Psychiatry, 46(7), 735-754
11. Cohen, J. A., Mannarina, A. P., Perel, J. M., & Staron, V. (2007). A pilot randomized controlled trial of combined trauma-focused CBT and sertraline for childhood PTSD symptoms. Journal of the American Academy of Child and Adolescent Psychiatry, 46(7), 811-819
12. Cornelius, J. R., Bukstein, O. G., Wood, S. D., Kirisci, L. Douaihy, A., & Clark, D. B. (2009). Double-blind placebo-controlled trial of fluoxetine in adolescents with comorbid major depression and an alcohol use disorder. Addictive Behaviors, 34(1), 905-909
13. Courtney, D. B. (2004). Selective serotonin reuptake inhibitor and venlafaxine use in children and adolescents with major depressive disorder: a systematic review of published randomized controlled trials. Canadian Journal of Psychiatry, 49(8), 557-563
14. Donnelly, C. L., Wagner, K. D., Rynn, M., Ambrosini, P. Landau, P., Yang, R., et al. (2006). Sertraline in children and adolescents with major depressive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 45(19), 1162-1170
15. Emslie, G. J., Kennard, B. D., Mayes, T. L., Nightingale-Teresi, J., Carmody, T., Hughes, C. W., et al. (2008). Fluoxetine versus placebo in preventing relapse of major depression in children and adolescents. American Journal of Psychiatry, 165(4), 459-467
16. Emslie, G. J., Wagner, K. D., Kutcher, S., Krulewicz, S., Fong, R., Carpenter, D. J., et al. (2006). Paroxetine treatment in children and adolescents with major depressive disorder: a randomized, multicenter, double-blind, placebo-controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 45(6), 709-719
17. Emslie, G. J., Heiligenstein, J. H., Hoog, S. L., Wagner, K. D., Findling, R. L., McCracken, J. T., et al. (2004). Fluoxetine treatment for prevention of relapse of depression in children and adolescents: a double-blind, placebo-controlled study. Journal of the American Academy of Child and Adolescent Psychiatry, 43(11), 1397-1405
18. Emslie, G. J., Heiligenstine, J. H., Wagner, K. D., Hoog, S. L., Ernest, D. E., Brown, E., et al. (2002). Fluoxetine for acute treatment of depression in children and adolescents: a placebo-controlled, randomized clinical trial. Journal of the American Academy of Child and Adolescent Psychiatry, 41(10), 1205-1215
19. Emslie, G. J., Rush, J. A., Weinberg, W. A., Kowatch, R. A., Hughes, C. W., Carmody, T., et al. (1997). A double-blind, randomized, placebo-controlled trial of fluoxetine in children and adolescents with depression. Archives of General Psychiatry, 54, 1031-1037
20. Findling, R. J., Pagano, M. E., McNamara, N. K., Stansbrey, R. J., Faber, J. E., Lingler, J., et al. (2009). The short-term safety and efficacy of fluoxetine in depressed adolescents with alcohol and cannabis use disorders: a pilot randomized placebo-controlled trial. Child and Adolescent Psychiatry and Mental Health, 3(11), 1-13
21. Food and Drug Administration (2010). Atypical antipsychotic drugs information. Retrieved 11/23, 2009, from http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm094303.htm
22. Garland, E. J., Virani, A., & Kutcher, S. (2009). 2008 Position paper on using SSRIs in children and adolescents. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 18(2), 160-165
23. Geller, D. A., Wagner, K. D., Emslie, G., Murphy, T., Carpenter, D. J., Wetherhold, E., et al. (2004). Paroxetine treatment in children and adolescents with obsessive-compulsive disorder: a randomized, multicenter, double-blind, placebo-controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 43(11), 1387-1396
24. Geller, D. A., Hoog, S. L., Heiligenstein, J. H., Ricardi, R. K., Tamura, R., Kluszynski, S., et al. (2001). Fluoxetine treatment for obsessive-compulsive disorder in children and adolescents: a placebo-controlled clinical trial. Journal of the American Academy of Child and Adolescent Psychiatry, 40(7), 773-779
25. Goodyer, I. M., Dubicka, B., Wilkinson, P., Kelvin, R., Roberts, C., Byford, S., et al. (2008). A randomised controlled trial of cognitive behaviour therapy in adolescents with major depression treated by selective serotonin reuptake inhibitors. The ADAPT trial. Health Technology Assessment, 12(14), 1-4
26. Goodyer, I., Dubicka, B., Wilkinson, P., Kelvin, R., Roberts, C., Byford, S., et al. (2007). Selective serotonin reuptake inhibitors (SSRIs) and routine specialist care with and without cognitive behavior therapy in adolescents with major depression: randomized controlled trial. British Medical Journal, 335(7611), 142-150
27. Health Canada (2010). Drug product search. Retrieved 02/02, 2010, from http://webprod.hc-sc.gc.ca/dpd-bdpp/index-eng.jsp
28. Hollander, E., Phillips, A., Chaplin, W., Zagursky, K., Novotny, S., Wasserman, S., et al. (2005). A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism. Neuropsychopharmacology, 30(1), 582-589
29. Impact BC (2010). Practice Support Program-Mental Health Youth-Tools & Resources. Impact BC Health Improvement Action. Retrieved 02/05, 2010, from http://www.impactbc.ca/practicesupport/mentalhealthyouth/toolsandresources
30. Keeton, C. P., Kolos, A. C., & Walkup, J. T. (2009). Pediatric Generalized Anxiety Disorder. Pediatric Drugs, 11(3), 171-183
31. Keller, M. B., Ryan, N. D., Strober, M., Klein, R. G., Kutcher, S. P., Birmaher, B., et al. (2001). Efficacy of paroxetine in the treatment of adolescent major depression: a randomized, controlled trial. Journal of American Academy of Child and Adolescent Psychiatry, 40(7), 762-772
32. King, B. H., Hollander, E., Sikich, L., McCracken, J. T., Scahill, L., Bregman, J. D., et al. (2009). Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior. Archives of General Psychiatry, 66(6), 583-590
33. Kratochvil, C. J., Newcorn, J. H., Arnold, L. E., Duesenberg, D., Emslie, G. J., Quintana, H., et al. (2005). Atomoxetine alone or combined with fluoxetine for treating ADHD with comorbid depressive or anxiety symptoms. Journal of the American Academy of Child and Adolescent Psychiatry, 44(9), 915-924
34. Liebowitz, M. R., Turner, S. M., Piacentini, J., Beidel, D. C., Clarvit, S. R., Davies, S. O., et al. (2002). Fluoxetine in children and adolescents with OCD: a placebo-controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 41(12), 1431-1438
35. Mandoki, M. W., Tapia, M. R., Tapia, M. A., Sumner, G. S., & Parker, J. L. (1997). Venlafaxine in the treatment of children and adolescents with major depression. Psychopharmacology Bulletin, 33(1), 149-154
36. March, J. S., Silva, S., Petrycki, S., Curry, J., Wells, K., Fairbank, J., et al. (2009). The Treatment for adolescents with depression study (TADS): outcomes over 1 year of naturalistic follow-up. American Journal of Psychiatry, 166(10), 1141-1149
37. March, J. S., Entusah, A. R., Rynn, M., Albano, A. M., & Tourian, K. A. (2007). A randomized controlled trial of venlafaxine ER versus placebo in pediatric social anxiety disorder. Biological Psychiatry, 62(1), 1149-1154
38. March, J. S., Foa, E., Gammon, P., Chrisman, A., Curry, J., Fitzgerald, D., et al. (2004a). Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: The Pediatric OCD treatment study (POTS) randomized controlled trial. Journal of the American Medical Association, 292(16), 1969-1976
39. March, J. S., Silva, S., Petrycki, S., Curry, J., Wells, K., Fairbank, J., et al. (2004b). Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression: treatment for adolescents with depression study (TADS) randomized controlled trial. Journal of the American Medical Association, 292(7), 807-820
40. March, J. S., Biederman, J., Wolkow, R., Safferman, A., Mardekian, J., Cook, E. H., et al. (1998). Sertraline in children and adolescents with obsessive-compulsive disorder. Journal of the American Medical Association, 280(20), 1752-1756
41. Melvin, G. A., Tonge, B. J., King, N. J., Heyne, D., Gordon, M. S., & Klimkeit, E. (2006). A comparison of cognitive-behavioral therapy, sertraline, and their combination for adolescent depression. Journal of the American Academy of Child and Adolescent Psychiatry, 45(10), 1151-1161
42. Pharmacare (2010). Policy, outcomes evaluation and research, pharmaceutical services division, ministry of health services. Unpublished manuscript.
43. Riddle, M. A., Reeve, E. A., Yaryura-Tobias, J. A., Yang, H. M., Claghorn, J. L., Gaffney, G., et al. (2001). Fluvoxamine for children and adolescents with obsessive-compulsive disorder: a randomized, controlled, multicenter trial. Journal of the American Academy of Child and Adolescent Psychiatry, 40(2), 222-229
44. Riddle, M. A., Scahill, L., King, R. A., Hardin, M. T., Anderson, G. M., Ort, S. I., et al. (1992). Double-blind, crossover trial of fluoxetine and placebo in children and adolescents with obsessive-compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 31(6), 1062-1069
45. Rushton, J. L, Clark, S. J., & Freed, G. L. (2000). Pediatrician and family physician prescription of selective serotonin reuptake inhibitors. Journal of the American Academy of Pediatrics, 105(6), 82-90
46. Rynn, M. A., Riddle, M. A., Yeung, P. P., & Kunz, N. R. (2007). Efficacy and safety of extended-release venlafaxine in the treatment of generalized anxiety disorder in children and adolescents: two placebo-controlled trials. American Journal of Psychiatry, 164(2), 290-300
47. Rynn, M. A., Siqueland, L., & Rickels, K. (2001). Placebo-controlled trial of sertraline in the treatment of children with generalized anxiety disorder. American Journal of Psychiatry, 158(12), 2008-2014
48. Simeon, J. G., Dinicola, V. F., Ferguson, H. B., & Copping, W. (1990). Adolescent depression: a placebo-controlled fluoxetine treatment study and follow up. Programming Neuro-Psychopharmacology & Biological Psychiatry, 1990(14), 791-795
49. Von Knorring, A., Olsson, G. I., Thomsen, P. H., Lemming, O. M., & Hulten, A. (2006). A randomized, double-blind, placebo-controlled study of citalopram in adolescents with major depressive disorder. Journal of Clinical Psychopharmacology, 26(3), 311-315
50. Wagner, K. D., Jonas, J., Findling, R. L., Ventura, D., & Saikali, K. (2006). A double-blind, randomized, placebo-controlled trial of escitalopram in the treatment of pediatric depression. Journal of the American Academy of Child and Adolescent Psychiatry, 45(3), 280-288
51. Wagner, K. D., Berard, R., Stein, M. B., Wetherhold, E., Carpenter, D. J., Perera, P., et al. (2004a). A multicenter, randomized, double-blind, placebo-controlled trial of paroxetine in children and adolescents with social anxiety disorder. Archives of General Psychiatry, 61(11), 1153-1162
52. Wagner, K. D., Robb, A. S., Findling, R. L., Jin, J., Gutierrez, M. M., & Heydorn, W. E. (2004b). A randomized, placebo-controlled trial of citalopram for the treatment of major depression in children and adolescents. American Journal of Psychiatry, 161(6), 1079-1083
53. Wagner, K. D., Ambrosini, P., Rynn, M., Wohlberg, C., Yang, R., Greenbaum, M. S., et al. (2003). Efficacy of sertraline in the treatment of children and adolescents with major depressive disorder: two randomized controlled trials. Journal of the American Medical Association, 290(8), 1033-1041
54. Walkup, J. T., Albano, A. M., Piacentini, J., Birmaher, B., Compton, S. N., Sherrill, J. T., et al. (2008). Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety. New England Journal of Medicine, 359(26), 2753-2766
55. Walkup, J. T., Labellarte, M. J., Riddle M. A., Pine, D. S., Greenhill, L., Klein, R., et al. (2001). Fluvoxamine for the treatment of anxiety disorders in children and adolescents. New England Journal of Medicine, 344(17), 1279-1285
56. Zinck, S., Bagnell A., Bond K., & Newton A. S. (2009). The Cochrane Library and the treatment of major depression in children and youth: an overview of reviews. Evidence-based child health: a Cochrane review journal, 4(1), 1336-1350
57. Zito, J. M., Safer, D. J., dosReis, S., Garnder, J. F., Soeken, K., Boles, M., et al. (2002). Rising prevalence of antidepressants among US youths. Pediatrics, 109(5), 721-727.