C5a-inhibitory peptide combined with gabexate mesilate prevents the instant blood-mediated inflammatory reaction in a rat model of islet transplantation

Transplantation Proceedings

Volumn 42, Issue 6, 2010, Pages 2102-2103

  Tokodai, K ^a   Goto, M ^a   Inagaki, A ^a   Nakanishi, W ^a   Okada, N ^b   Okada, H ^c   Satomi, S ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b NAGOYA CITY UNIVERSITY   (Japan)

^c Choju Medical Institute Fukushimura Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN; C5A INHIBITORY PEPTIDE; COMPLEMENT COMPONENT C3A RECEPTOR; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT RECEPTOR; GABEXATE; GABEXATE MESILATE; INSULIN; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BLOOD ANALYSIS; BODY WEIGHT; CONFERENCE PAPER; CONTROLLED STUDY; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INSTANT BLOOD MEDIATED INFLAMMATORY REACTION; INTRAVENOUS GLUCOSE TOLERANCE TEST; ISOLATION PROCEDURE; MOLECULAR WEIGHT; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES;

ANIMALS; ANTICOAGULANTS; BLOOD GLUCOSE; COMPLEMENT C5A; GABEXATE; IMMUNOLOGIC FACTORS; INFLAMMATION; ISLETS OF LANGERHANS TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS; RATS; RECEPTOR, ANAPHYLATOXIN C5A; TRANSPLANTATION, ISOGENEIC;

EID: 77955533583     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2010.05.100     Document Type: Conference Paper

References (4)

1. W. Bennet, B. Sundberg, and T. Lundgren Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin Transplantation 69 2000 711
2. M. Goto, B. Nilsson, and O. Korsgren Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood-mediated inflammatory reaction Xenotransplantation 11 2004 195
3. M. Goto, H. Johansson, and A. Maeda Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets Transplantation 77 2004 741
4. E. Fujita, H. Okada, and N. Okada Inactivation of C5a anaphylatoxin by a peptide that is complementary to a region of C5a J Immunol 172 2004 6382