Use of chewing gum containing 15% of xylitol and reduction in mutans streptococci salivary levels

Brazilian Oral Research

Volumn 24, Issue 2, 2010, Pages 142-146

  Fraga, Cláudia Perez Trindade ^a   Mayer, Márcia Pinto Alves ^a   Delgado, Célia Regina Martins ^a   Rodrigues, ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Chewing gum; Saliva; Streptococcus mutans; Xylitol

Indexed keywords

SWEETENING AGENT; XYLITOL;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; BACTERIAL COUNT; CHEWING GUM; DRUG EFFECT; FEMALE; GROWTH, DEVELOPMENT AND AGING; HUMAN; MALE; MICROBIOLOGY; SALIVA; STREPTOCOCCUS MUTANS; TIME;

ADULT; ANALYSIS OF VARIANCE; CHEWING GUM; COLONY COUNT, MICROBIAL; FEMALE; HUMANS; MALE; SALIVA; STREPTOCOCCUS MUTANS; SWEETENING AGENTS; TIME FACTORS; XYLITOL; YOUNG ADULT;

EID: 77955529411     PISSN: 18068324     EISSN: 18073107     Source Type: Journal    
DOI: 10.1590/S1806-83242010000200003     Document Type: Article

References (30)

1. Caglar E, Kavaloglu SC, Kuscu OO, Sandalli N, Holgerson PL, Twetman S. Effect of chewing gums containing xylitol or probiotic bacteria on salivary mutans streptococci and lactobacilli. Clin Oral Investig. 2007 Dec;11(4):425-9.
2. Vagstrand K, Karin LA, Birkhed D, Linne Y. Associations between salivary bacteria and reported sugar intake and their relationship with body mass index in women and their adolescent children. Public Health Nutr. 2008 Apr;11(4):341-8.
3. Marsh PD. Plaque as a biofilm: pharmacological principles of drug delivery and action in the sub-and supragingival environment. Oral Dis. 2003;9 Suppl 1:16-22.
4. Kleinberg I. A mixed-bacteria ecological approach to understanding the role of the oral bacteria in dental caries causation: an alternative to Streptococcus mutans and the specific-plaque hypothesis. Crit Rev Oral Biol Med. 2002;13(2):108-25.
5. Hata S, Mayanagy H. Acid diffusion through extracellular polysaccharides produced by various mutants of Streptococcus mutans. Arch Oral Biol. 2003 Jun;48(6):431-8.
6. Söderling E, Isokangas P, Pienihakkinen K, Tenovuo J, Alanen P. Influence of maternal xylitol consumption on mother-child transmission of mutans streptococci: 6-Year follow-up. Caries Res. 2001 May-Jun;35(3):173-7.
7. Assev S, Stig S, Scheie AA. Cariogenic traits in xylitol-resistant and xylitol sensitive mutans streptococci. Oral Microbiol Immunol. 2002 Apr;17(2):95-9.
8. Wennerholm K, Arends J, Birkhed D, Ruben J, Emilson CG, Dijkman AG. Effect of xylitol and sorbitol in chewing-gums on mutans streptococci, plaque pH and mineral loss of enamel. Caries Res. 1994 Jan-Feb;28(1):48-54.
9. Ly KA, Milgrom P, Rothen M. Xylitol, sweetners and dental caries. Pediatr Dent. 2006 Mar-Apr; 28(2):154-63.
10. Burt BA. The use of sorbitol-and xylitol-sweetened chewing gum in caries control. J Am Dent Assoc. 2006 Feb;137(2):190-6.
11. Ly KA, Milgrom P., Rothen M. The potencial of dental-protective chewing gum in oral health interventions. J Am Dent Assoc. 2008 May;139(5):553-63.
12. Makinen KK, Alanen P, Isokangas P, Isotupa K, Soderling E, Makinen PL, et al. Thirty-nine-month xylitol chewing-gum programme in initially 8-year-old school children: a feasibility study focusing on mutans streptococci and lactobacilli. Int Dent J. 2008 Feb;58 (1):41-50.
13. Van Loveren C. Sugar Alcohols: what is the evidence for caries-preventive and caries-therapeutic effects? Caries Res. 2004 May-Jun;38(3):286-93.
14. Thorild I, Lindau B, Twetman S. Caries in 4-year-old children after maternal chewing of gums containing combinations of xylitol, sorbitol, chlorhexidine and fluoride. Eur Arch Paediatr Dent. 2006 Dec;7(4):241-5.
15. Ly KA, Milgrom P, Roberts MC, Yamaguchi DK, Rothen M, Mueller G. Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial. BMC Oral Health. 2006 Mar 24;6:6.
16. Zero DT. Are sugar substitutes also anticariogenic? J Am Dent Assoc. 2008 May;139 Suppl:9S-10S.
17. Tanzer JM, Thompson AS, Wen ZT, Burne R. So called xilitol resistence is associated with partial loss of cariogenicity of Streptococcus mutans. J Dent Res. 2006 Apr;85(4):369-73.
18. Lif Holgerson P, Stecksen-Blicks C, Sjostrom I, Twetman S. Effect of xylitol-containing chewing gums on interdental plaque-pH in habitual xylitol consumers. Acta Odontol Scand. 2005 Aug;63(4):233-8.
19. Holgerson PL, Sjostrom I, Twetman S. Decreased salivary uptake of [14C]-xylitol after a four-week xylitol chewing gum regimen. Oral Health Prev Dent. 2007;5(4):313-9.
20. Thaweboon S, Thaweboon B, Soo-Ampon S. The effect of xylitol chewing gum on mutans streptococci in saliva and 146 Braz Oral Res. 2010 Apr-Jun;24(2):142-6 dental plaque. Southeast Asian J Trop Med Public Health. 2004 Dec;35(4):1024-7.
21. Massoth D, Massoth G, Massoth IR, Laflamme L, Shi W, Hu C, et al. The effect of xylitol on Streptococcus mutans in children. J Calif Dent Assoc. 2006 Mar;34(3):231-4.
22. Haresaku S, Hanioka T, Tsutsui A, Yamamoto M, Chou T, Gunjishima Y Long-term effect of xylitol gum use on mutans streptococci in adults. Caries Res. 2007 May-Jun;41(3):198-203.
23. Söderling E, Isokangas P, Pienihakkinen K, Tenovuo J. Influence of maternal xylitol consumption on acquisition of mutans streptococci by infants. J Dent Res. 2000 Mar;79(3):882-7.
24. Isokangas P, Söderling E, Pienihakkinen K, Alanen P. Occurrence of dental decay in children after maternal maternal consumption of xylitol chewinig gum, a follow-up from 0 to 5 years of age. J Dent Res. 2000 Nov;79(11):1885-9.
25. Thorild I, Lindau B, Twetman S. Salivary mutans streptococci and dental caries in three-year-old children after maternal exposure to chewing gums containing combinations of xylitol, sorbitol, chlorhexidine, and fluoride. Acta Odontol Scand. 2004 Oct;62(5):245-50.
26. Decker EM, Maier G, Axmann D, Brecx M, von Ohle C. Effect of xylitol/chlorhexidine versus xylitol or chlorhexidine as single rinses on initial biofilm formation of cariogenic streptococci. Quintessence Int. 2008 Jan;39(1):17-22.
27. Köhler B, Andrèen I, Jonsson B. The earlier the colonization by mutans streptococci, the higher the caries prevalence at 4 years of age. Oral Microbiol Immunol. 1988 Mar;3(1):14-7.
28. Zickert I, Emilson CG, Krasse B. Effect of caries preventive measures in children highly infected with the bacterium Streptococcus mutans. Arch Oral Biol. 1982;27(10):861-8.
29. Deshpande A, Jadad AR. The impact of polyol-containing chewing gums on dental caries. A systematic review of original randomized controlled trials and observational studies. J Am Dent Assoc. 2008 Dec;139(12):1602-14.
30. Emilson CG, Lindquist B, Wennerholm K. Recolonization of human tooth surfaces by Streptococcus mutans after suppression by chlorhexidine treatment. J Dent Res. 1987 Sep;66(9):1503-8.