Total joint replacement in the elderly patient

Clinics in Geriatric Medicine

Volumn 26, Issue 3, 2010, Pages 517-529

  Talmo, Carl T ^a   Robbins, Claire E ^b   Bono, James V ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

Author keywords

Older adults; Osteoarthritis; Total hip arthroplasty; Total knee arthroplasty

Indexed keywords

ACETYLSALICYLIC ACID; ANTIBIOTIC AGENT; BLOOD CLOTTING FACTOR 10A INHIBITOR; CEPHALOSPORIN; CORTICOSTEROID; CORTISONE; DONEPEZIL; HALOPERIDOL; LOW MOLECULAR WEIGHT HEPARIN; NONSTEROID ANTIINFLAMMATORY AGENT; OLANZAPINE; PARACETAMOL; PENTASACCHARIDE; PLACEBO; RISPERIDONE; WARFARIN;

AGING; BLEEDING; BONE RADIOGRAPHY; COMPRESSION GARMENT; CONFUSION; DELIRIUM; DRUG CHOICE; DRUG EFFICACY; HIP OSTEOARTHRITIS; HOSPITAL COST; HUMAN; INFECTIOUS ARTHRITIS; JOINT PROSTHESIS; KNEE OSTEOARTHRITIS; KNEE PAIN; LOW DRUG DOSE; MEDICARE; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOARTHRITIS; PATIENT SATISFACTION; PEPTIC ULCER; PERIOPERATIVE PERIOD; POSTOPERATIVE INFECTION; PREVALENCE; PROSTHESIS INFECTION; REIMBURSEMENT; REVIEW; SAFETY; THROMBOEMBOLISM; TOTAL HIP PROSTHESIS; TOTAL KNEE REPLACEMENT; TREATMENT RESPONSE; WALKING AID; WEIGHT REDUCTION;

AGE FACTORS; AGED; ARTHROPLASTY, REPLACEMENT; HUMANS; OSTEOARTHRITIS; RISK FACTORS; TREATMENT OUTCOME;

EID: 77955498017     PISSN: 07490690     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cger.2010.04.002     Document Type: Review

References (63)

1. Population profile. The elderly population Available at:, Accessed February 26, 2010. http://www.census.gov/population/www/pop-profile/elderpop.html.
2. We, the American elderly Available at:, Accessed February 26, 2010. http://www.census.gov/apsd/wepeople/we-9.pdf.
3. Administration on Aging. Aging statistics Available at:, Accessed February 26, 2010. http://www.aoa.gov/aoaroot/aging_statistics/index.aspx.
4. Goldberg V.M., Buckwalter J.A., Hayes W.C., et al. Orthopaedic challenges in an aging population. Instr Course Lect 1997, 46:417-422.
5. Brummel-Smith K. Geriatrics for orthopaedics. Instr Course Lect 1997, 46:409-416.
6. Day S. Geriatric orthopaedics. New frontiers in the geriatrics research 2004, 303. American Geriatric Society, New York. D. Solomon (Ed.).
7. Laupacis A., Bourne R., Rorabeck C., et al. The effect of elective total hip replacement on health-related quality of life. J Bone Joint Surg Am 1993, 75(11):1619.
8. Ethgen O., Bruyere O., Richy F., et al. Health-related quality of life in total hip and total knee arthroplasty, a qualitative and systematic review of the literature. J Bone Joint Surg Am 2004, 86(5):963-974.
9. Birdsall P.D., Hayes J.H., Cleary R., et al. Health outcome after total knee replacement in the very elderly. J Bone Joint Surg Br 1999, 81:660-662.
10. Levy R.N., Levy C.M., Snyder J., et al. Outcome and long-term results following total hip replacement in elderly patients. Clin Orthop 1995, 316:25-30.
11. Hamel M.B., Toth M., Legedza A., et al. Joint replacement surgery in elderly patients with severe osteoarthritis of the hip or knee. Arch Intern Med 2008, 168:1430-1440.
12. March L.M., Cross M.J., Lapsley H., et al. Outcomes after hip or knee replacement surgery for osteoarthritis: a prospective cohort study comparing patients quality of life before and after surgery with age-related population norms. Med J Aust 1999, 171:235-238.
13. Hozack J., Rothman R.H., Albert T.J., et al. Relationship of total hip arthroplasty outcomes to other orthopedic procedures. Clin Orthop 1997, 344:81-87.
14. Lieberman J.R., Dorey F., Shekelle P., et al. Outcome after total hip arthroplasty. Comparison of traditional disease-specific and a quality of life measurement of outcome. J Arthroplasty 1997, 12:639-645.
15. Kiebzak G.M., Vain P.A., Gregory A.M., et al. SF-36 general health status survey to determine patient satisfaction at short-term follow-up after total hip and knee arthroplasty. J South Orthop Assoc 1997, 6:169-172.
16. Ritter M.A., Albohm M.J., Keating E.M., et al. Comparative outcomes of total joint arthroplasty. J Arthroplasty 1995, 10:737-741.
17. Learmonth I.D., Young C., Rorabeck C. The operation of the century: total hip replacement. Lancet 2007, 370:1508-1519.
18. Saleh K.J., Wood K.C., Gafni A., et al. Immediate surgery versus waiting list policy in revision total hip arthroplasty. An economic evaluation. J Arthroplasty 1997, 12:1-10.
19. Lohmander S. Osteoarthritis: a major cause of disability in the elderly. Musculoskeletal soft-tissue aging: impact on mobility 1993, 99-115. American Academy of Orthopaedic Surgeons, Rosemont (IL). J.A. Buckwalter, V.M. Goldwater, S.L.Y. Woo (Eds.).
20. Hochberg M.C., Altman R.D., Brandt K.D., et al. Guidelines for the medical management of osteoarthritis. Part I. Osteoarthritis of the hip. American College of Rheumatology. Arthritis Rheum 1995, 38:1535-1540.
21. Iorio R., Robb W.J., Healy W.L., et al. Orthopaedic surgeon workforce and volume assessment for total hip and knee replacement in the United States: preparing for an epidemic. J Bone Joint Surg Am 2008, 90:1598-1605.
22. Kurtz S.M., Ong K.L., Schmier J., et al. Future clinical and economic impact of revision total hip and knee arthroplasty. J Bone Joint Surg Am 2007, 89:144-151.
23. Kurtz S.M., Ong K., Lau E., et al. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am 2007, 89:780-785.
24. Bozik K.J., Saleh K.J., Rosenberg A.G., et al. Economic evaluation of total hip arthroplasty: analysis and review of the literature. J Arthroplasty 2004, 19:180-189.
25. Barber T., Healy W. The hospital cost of total hip arthroplasty. J Bone Joint Surg Am 1993, 75:321-325.
26. Adams M.E., Atkinson M.H., Lussier A.J., et al. The role of viscosupplementation with hylan G-F 20 in treatment of osteoarthritis of the knee: a Canadian multicenter trial comparing hylan G-F 20 alone, hylan G-F 20 with non-steroidal anti-inflammatory drugs and NSAIDs alone. Osteoarthritis Cartilage 1995, 3:213-225.
27. Nallamshetty L., Buchowski J.M., Nazarian L.A., et al. Septic arthritis of the hip following cortisone injection: case report and review of the literature. Clin Imaging 2003, 27(4):225-228.
28. Butler R.N., Davis R., Lewis C.B., et al. Physical fitness: benefits of exercise for the older patient. Geriatrics 1998, 53:46-52.
29. Shah A.K., Celestin J., Parks M.L., et al. Long-term results of total joint arthroplasty in elderly patients who are frail. Clin Orthop 2004, 425:106-109.
30. Chang R.W., Pellissier J.M., Hazen G.B. A cost-effectiveness analysis of total hip arthroplasty for osteoarthritis of the hip. JAMA 1996, 275:858-865.
31. Mahomed N.N., Barrett J.A., Katz J.N., et al. Rates and outcomes of primary and revision total hip replacement in the United States Medicare population. J Bone Joint Surg Am 2003, 85(1):27-32.
32. Petersen V.S., Solgaard S., Simonsen B. Total hip replacement in patients aged 80 years and older. J Am Geriatr Soc 1989, 37:219-222.
33. Brander A.B., Malhotra S., Jet J., et al. Outcome of hip and knee arthroplasty in persons aged 80 years and older. Clin Orthop 1997, 345:67-78.
34. Jones C.A., Voaklander D.C., Johnston W.C., et al. The effect of age on pain, function, and quality of life after total hip and knee arthroplasty. Arch Intern Med 2001, 161:454-460.
35. Zicat B., Rorabeck C.H., Bourne R.B., et al. Total knee arthroplasty in the octogenarian. J Arthroplasty 1993, 8:395-400.
36. Pettine K.A., Aamlid B.C., Cabanela M.E. Elective total hip arthroplasty in patients older than 80 years of age. Clin Orthop 1991, 266:127-132.
37. Keisu K.S., Orozco F., Sharkey P.F., et al. Primary cementless total hip arthroplasty in octogenarians. Two to eleven-year follow-up. J Bone Joint Surg Am 2001, 83(3):359-363.
38. Katz B.P., Freund D.A., Heck D.A., et al. Demographic variation in the rate of knee replacement: a multi-year analysis. Health Serv Res 1996, 31:125-140.
39. Hernandez-Vaquero D., Fernandez-Carreira J.M., Perez-Hernandez D., et al. Total knee arthroplasty in the elderly. Is there an age limit?. J Arthroplasty 2006, 21:358-361.
40. Biau D., Mullins M.M., Judet T., et al. Is anyone too old for a total knee replacement?. Clin Orthop 2006, 448:180-184.
41. Karuppiah S.V., Banaszkiewicz P.A., Ledingham W.M. The mortality, morbidity and cost benefits of elective total knee arthroplasty in the nonagenarian population. Int Orthop 2008, 32:339-343.
42. Adam R.F., Noble J. Primary total knee arthroplasty in the elderly. J Arthroplasty 1994, 9:495-497.
43. Hosick W.B., Lotke P.A., Baldwin A. Total knee arthroplasty in patients 80 years of age and older. Clin Orthop 1994, 299:77-80.
44. Newington D.P., Bannister G.C., Fordyce M. Primary total hip replacement in patients over 80 years of age. J Bone Joint Surg Br 1990, 72:450-452.
45. Phillips T.W., Grainger R.W., Cameron H.S., et al. Risks and benefits of elective hip replacement in the octogenarian. CMAJ 1987, 137:497-500.
46. Berry D.J., von Knoch M., Schleck C.D., et al. The cumulative long-term risk of dislocation after primary Charnley total hip arthroplasty. J Bone Joint Surg Am 2004, 86(1):9-14.
47. Mantilla C.B., Horlocker T.T., Schroeder D.R., et al. Frequency of myocardial infarction, pulmonary embolism, deep venous thrombosis and death following primary hip or knee arthroplasty. Anesthesiology 2002, 96(5):1140-1146.
48. Lee J., Singletary R., Schmader K., et al. Surgical site infection in the elderly following orthopaedic surgery, risk factors and outcomes. J Bone Joint Surg Am 2006, 88:1705-1712.
49. Kurtz S.M., Ong K.L., Lau E., et al. Prosthetic joint infection risk after TKA in the Medicare population. Clin Orthop 2010, 468:52-56.
50. Leone J.M., Hanssen A.D. Management of infection at the site of a total knee arthroplasty. J Bone Joint Surg Am 2005, 87:2335-2348.
51. Peersman G., Laskin R., Davis G., et al. Infection in knee replacement: a retrospective review of 6489 total knee replacements. Clin Orthop 2001, 392:15-23.
52. Pulido L., Ghanem E., Joshi A., et al. Periprosthetic joint infection: the incidence, timing and predisposing factors. Clin Orthop 2008, 466(7):1710-1715.
53. Patel V.P., Walsh M., Sehgal B., et al. Factors associated with prolonged wound drainage after primary total hip and knee arthroplasty. J Bone Joint Surg Am 2007, 89(1):33-38.
54. Jamsen E., Huhtala H., Puolakka T., et al. Risk factors for infection after knee arthroplasty, a register-based analysis of 43,149 cases. J Bone Joint Surg Am 2009, 91(1):38-47.
55. Masterson E.L., Masri B.A., Duncan C.P. Treatment of infection at the site of total hip replacement. J Bone Joint Surg Am 1997, 79:1740-1749.
56. Lieberman J.R., Hsu W.K. Prevention of venous thromboembolic disease after total hip and knee arthroplasty. J Bone Joint Surg Am 2005, 87:2097-2112.
57. Johanson N.A., Lachiewicz P.F., Lieberman J.R., et al. Prevention of symptomatic pulmonary embolism in patients undergoing total hip or knee arthroplasty. J Am Acad Orthop Surg 2009, 17(3):183-196.
58. Bern M., Deshmukh R.V., Nelso R., et al. Low-dose warfarin coupled with lower leg compression is effective prophylaxis against thromboembolic disease after hip arthroplasty. J Arthroplasty 2007, 22:644-650.
59. Inouye S.K. Delirium in older persons. N Engl J Med 2006, 354:1157-1165.
60. Robinson T.N., Raeburn C.D., Tran Z.V., et al. Postoperative delirium in the elderly: risk factors and outcomes. Ann Surg 2009, 249:173-178.
61. Sampson E.L., Raven P.R., Ndhlovu P.N., et al. A randomized, double-blind, placebo-controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement. Int J Geriatr Psychiatry 2007, 22:343-349.
62. Larsen KA, Kelly SE, Stern TA, et al. Administration of olanzapine to prevent postoperative delirium in the elderly joint replacement patient: a randomized controlled trial. Psychosomatics 2010, in press.
63. Leslie D.L., Marcantonio E.R., Zhang Y., et al. One-year health care costs associated with delirium in the elderly population. Arch Intern Med 2008, 168:27-32.