Electrospinning of ultrafine core/shell fibers for biomedical applications

Science China Chemistry

Volumn 53, Issue 6, 2010, Pages 1246-1254

  Zhang, Hong ^a   Zhao, Chenguang ^a   Zhao, Yunhui ^a   Tang, Gongwen ^a   Yuan, Xiaoyan ^a  

^a TIANJIN UNIVERSITY   (China)

Author keywords

coaxial electrospinning; controlled delivery; core shell fibers; emulsion electrospinning; tissue engineering

Indexed keywords

COAXIAL ELECTROSPINNING; CONTROLLED DELIVERY; CORE/SHELL; CORE/SHELL FIBERS;

EMULSIFICATION; FIBERS; FIBROUS MEMBRANES; TISSUE; TISSUE ENGINEERING;

ELECTROSPINNING;

EID: 77955497251     PISSN: 16747291     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11426-010-3180-3     Document Type: Article

References (97)

1. Z.M. Huang Y.Z. Zhang M. Kotaki S. Ramakrishna 2003 A review on polymer nanofibers by electrospinning and their applications in nanocomposites Compos Sci Technol 63 15 2223 2253 10.1016/S0266-3538(03)00178-7 1:CAS:528: DC%2BD3sXmvVKlu7w%3D (Pubitemid 37124181)
2. S. Koombhongse W.X. Liu D.H. Reneker 2001 Flat polymer ribbons and other shapes by electrospinning J Polym Sci B-Polym Phys 39 21 2598 2606 10.1002/polb.10015 1:CAS:528:DC%2BD3MXnvVWks7o%3D (Pubitemid 33074469)
3. Q.P. Pham U. Sharma A.G. Mikos 2006 Electrospinning of polymeric nanofibers for tissue engineering applications: A review Tissue Eng 12 5 1197 1211 10.1089/ten.2006.12.1197 1:CAS:528:DC%2BD28XlsFeqtrc%3D (Pubitemid 44024491)
4. K. Kim M. Yu X.H. Zong J. Chiu D.F. Fang Y.-S. Seo B. S. Hsiao B. Chu M. Hadjiargyrou 2003 Control of degradation rate and hydrophilicity in electrospun non-woven poly(d,l-lactide) nanofiber scaffolds for biomedical applications Biomaterials 24 27 4977 4985 10.1016/S0142-9612(03)00407-1 1:CAS:528: DC%2BD3sXotVSjs7w%3D (Pubitemid 37237628)
5. F. Yang R. Murugan S. Wang S. Ramakrishna 2005 Electrospinning of nano/micro scale poly(l-lactic acid) aligned fibers and their potential in neural tissue engineering Biomaterials 26 15 2603 2610 10.1016/j.biomaterials. 2004.06.051 1:CAS:528:DC%2BD2cXhtVChsrzF (Pubitemid 39600712)
6. H. Yoshimoto Y.M. Shin H. Terai J.P. Vacanti 2003 A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering Biomaterials 24 12 2077 2082 10.1016/S0142-9612(02)00635-X 1:CAS:528:DC%2BD3sXhslGqtLo%3D (Pubitemid 36298779)
7. E.P.S. Tan S.Y. Ng C.T. Lim 2005 Tensile testing of a single ultrafine polymeric fiber Biomaterials 26 13 1453 1456 10.1016/j.biomaterials.2004.05.021 1:CAS:528:DC%2BD2cXptV2lsbg%3D (Pubitemid 39441377)
8. W.J. Li R. Tuli C. Okafor A. Derfoul K.G. Danielson D.J. Hall R.S. Tuan 2005 A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells Biomaterials 26 6 599 609 10.1016/j.biomaterials.2004.03.005 1:CAS:528:DC%2BD2cXmtFCntLk%3D (Pubitemid 38988302)
9. W.J. Li C.T. Laurencin E.J. Caterson R.S. Tuan F.K. Ko 2002 Electrospun nanofibrous structure: A novel scaffold for tissue engineering J Biomed Mater Res 60 4 613 621 10.1002/jbm.10167 1:CAS:528:DC%2BD38XjsFGksb4%3D (Pubitemid 34492600)
10. D.S. Katti K.W. Robinson F.K. Ko C.T. Laurencin 2004 Bioresorbable nanofiber-based systems for wound healing and drug delivery: Optimization of fabrication parameters J Biomed Mater Res 70B 2 286 296 10.1002/jbm.b.30041 1:CAS:528:DC%2BD2cXmtlygtbk%3D
11. B. Duan L.L. Wu X.Y. Yuan Z. Hu X.L. Li Y. Zhang K.D. Yao M. Wang 2007 Hybrid nanofibrous membranes of PLGA/chitosan fabricated via an electrospinning array J Biomed Mater Res 83A 3 868 878 10.1002/jbm.a.31408 1:CAS:528: DC%2BD2sXhtlWitLbJ (Pubitemid 350086315)
12. M.P. Prabhakaran J.R. Venugopal S. Ramakrishna 2009 Mesenchymal stem cell differentiation to neuronal cells on electrospun nanofibrous substrates for nerve tissue engineering Biomaterials 30 28 4996 5003 10.1016/j.biomaterials. 2009.05.057 1:CAS:528:DC%2BD1MXpt1Cisbk%3D
13. Y. Su X.Q. Li L.J. Tan C. Huang X.M. Mo 2009 Poly(l-lactide-co-ε- caprolactone) electrospun nanofibers for encapsulating and sustained releasing proteins Polymer 50 17 4212 4219 10.1016/j.polymer.2009.06.058 1:CAS:528:DC%2BD1MXptleqtbs%3D
14. K. Ohkawa D. Cha H. Kim A. Nishida H. Yamamoto 2004 Electrospinning of chitosan Macromol Rapid Comm 25 18 1600 1605 10.1002/marc.200400253 1:CAS:528:DC%2BD2cXotlGqsLc%3D
15. X.Y. Geng O.-H. Kwon J. Jang 2005 Electrospinning of chitosan dissolved in concentrated acetic acid solution Biomaterials 26 27 5427 5432 10.1016/j.biomaterials.2005.01.066 1:CAS:528:DC%2BD2MXjs1Wgu7Y%3D (Pubitemid 40592132)
16. J.A. Matthews G.E. Wnek D.G. Simpson G.L. Bowlin 2002 Electrospinning of collagen nanofibers Biomacromoleculars 3 2 232 238 10.1021/bm015533u 1:CAS:528:DC%2BD38Xnt1Gksw%3D%3D (Pubitemid 34257140)
17. S.P. Zhong W.E. Teo X. Zhu R.W. Beuerman S. Ramakrishna L.Y.L. Yung 2006 An aligned nanofibrous collagen scaffold by electrospinning and its effects on in vitro fibroblast culture J Biomed Mater Res 79A 3 456 463 10.1002/jbm.a.30870 1:CAS:528:DC%2BD28Xht1yjsLvI (Pubitemid 44845158)
18. Y.Z. Zhang H.W. Ouyang C.T. Lim S. Ramakrishna Z.M. Huang 2005 Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds J Biomed Mater Res 72B 1 156 165 10.1002/jbm.b.30128 1:CAS:528: DC%2BD2MXlsVSmtA%3D%3D (Pubitemid 40039622)
19. B.M. Min G. Lee S.H. Kim Y.S. Nam T.S. Lee W.H. Park 2004 Electrospinning of silk fibroin nanofibers and its effect on the adhesion and spreading of normal human keratinocytes and fibroblasts in vitro Biomaterials 25 7-8 1289 1297 10.1016/j.biomaterials.2003.08.045 1:CAS:528:DC%2BD3sXptFGrs7Y%3D (Pubitemid 37476206)
20. K. Ohgo C.H. Zhao M. Kobayashi T. Asakura 2003 Preparation of non-woven nanofibers of bombyx mori silk, samia cynthia ricini silk and recombinant hybrid silk with electrospinning method Polymer 44 3 841 846 10.1016/S0032-3861(02) 00819-4 1:CAS:528:DC%2BD38XpsFaqs7g%3D (Pubitemid 36083217)
21. T.C. Lu J. Sun X.Q. Dong X.S. Chen Y. Wang X.B. Jing 2009 PLLA-PCys co-electrospun fibers for capture and elution of glutathione S-transferase Sci China Ser B-Chem 52 12 2033 2037 10.1007/s11426-009-0291-9 1:CAS:528: DC%2BD1MXhsFyhs7zN
22. L. Jeong I.-S. Yeo H.N. Kim Y.I. Yoon D.H. Jang S. Y. Jung B.-M. Min W.H. Park 2009 Plasma-treated silk fibroin nanofibers for skin regeneration Int J Biol Macromol 44 3 222 228 10.1016/j.ijbiomac.2008.12.008 1:CAS:528: DC%2BD1MXit1Ohtrc%3D
23. J.S. Choi S.J. Lee G.J. Christ A. Atala J.J. Yoo 2008 The influence of electrospun aligned poly(ε-caprolactone)/collagen nanofiber meshes on the formation of self-aligned skeletal muscle myotubes Biomaterials 29 19 2899 2906 10.1016/j.biomaterials.2008.03.031 1:CAS:528:DC%2BD1cXlsV2mtbg%3D
24. S. Sahoo H. Ouyang J.-H. Goh T.E. Tay S.L. Toh 2006 Characterization of a novel polymeric scaffold for potential application in tendon/ligament tissue engineering Tissue Eng 12 1 91 99 10.1089/ten.2006.12.91 1:CAS:528: DC%2BD28XhslCjtLc%3D
25. H.S. Koh T. Yong C.K. Chan S. Ramakrishna 2008 Enhancement of neurite outgrowth using nano-structured scaffolds coupled with laminin Biomaterials 29 26 3574 3582 10.1016/j.biomaterials.2008.05.014 1:CAS:528:DC%2BD1cXotFCitLc%3D
26. J.M. Corey C.C. Gertz B.S. Wang L.K. Birrell S.L. Johnson D.C. Martin E.L. Feldman 2008 The design of electrospun PLLA nanofiber scaffolds compatible with serum-free growth of primary motor and sensory neurons Acta Biomater 4 4 863 875 10.1016/j.actbio.2008.02.020 1:CAS:528:DC%2BD1cXhtVarsr7I
27. A. Subramanian D. Vu G.F. Larsen H.Y. Lin 2005 Preparation and evaluation of the electrospunchitosan/PEO fibers for potential applications in cartilage tissue engineering J Biomat Sci-Polym Ed 16 7 861 873 10.1163/1568562054255682 1:CAS:528:DC%2BD2MXosVaksrc%3D (Pubitemid 40973998)
28. Y.Z. Zhang J.R. Venugopal A.E. Turki S. Ramakrishna B. Su C.T. Lim 2008 Electrospun biomimetic nanocomposite nanofibers of hydroxyapatite/chitosan for bone tissue engineering Biomaterials 29 32 4314 4322 10.1016/j.biomaterials. 2008.07.038 1:CAS:528:DC%2BD1cXhtVOqtrzO
29. Z.M. Huang C. L. He A.Z. Yang Y.Z. Zhang X.J. Han J. L. Yin Q.S. Wu 2006 Encapsulating drugs in biodegradable ultrafine fibers through co-axial electrospinning J Biomed Mater Res 77A 1 169 179 10.1002/jbm.a.30564 1:CAS:528:DC%2BD28XislyiurY%3D
30. H.L. Jiang Y.Q. Hu Y. Li P.C. Zhao K.J. Zhu W. Chen 2005 A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agents J Control Release 108 2-3 237 243 10.1016/j.jconrel.2005.08.006 1:CAS:528:DC%2BD2MXht1aiu7jP (Pubitemid 41608657)
31. Y. Lu H.L. Jiang K.H. Tu L.Q. Wang 2009 Mild immobilization of diverse macromolecular bioactive agents onto multifunctional fibrous membranes prepared by coaxial electrospinning Acta Biomater 5 5 1562 1574 10.1016/j.actbio.2009.01. 044 1:CAS:528:DC%2BD1MXms1Gksr0%3D
32. Y.Z. Zhang J. Venugopal Z.M. Huang C.T. Lim S. Ramakrishna 2005 Characterization of the surface biocompatibility of the electrospun PCL-collagen nanofibers using fibroblasts Biomacromolecules 6 5 2583 2589 10.1021/bm050314k 1:CAS:528:DC%2BD2MXmsFWnsrc%3D (Pubitemid 41388269)
33. P.C. Zhao H.L. Jiang H. Pan K.J. Zhu W.L. Chen 2007 Biodegradable fibrous scaffolds composed of gelatin coated poly(ε-caprolactone) prepared by coaxial electrospinning J Biomed Mater Res 83A 2 372 382 10.1002/jbm.a.31242 1:CAS:528:DC%2BD2sXhtFOnu77N (Pubitemid 47557386)
34. L.L. Wu H. Li S. Li X.R. Li X.Y. Yuan X.L. Li Y. Zhang 2010 Composite fibrous membranes of PLGA and chitosan prepared by coelectrospinning and coaxial electrospinning J Biomed Mater Res 92A 2 563 574 1:CAS:528:DC%2BD1MXhsF2itLfK
35. J.T. McCann D. Li Y.N. Xia 2005 Electrospinning of nanofibers with core-sheath, hollow, or porous structures J Mater Chem 15 7 735 738 10.1039/b415094e 1:CAS:528:DC%2BD2MXhtVyitLg%3D (Pubitemid 40314789)
36. D. Li Y.N. Xia 2004 Direct fabrication of composite and ceramic hollow nanofibers by electrospinning Nano Lett 4 5 933 938 10.1021/nl049590f 1:CAS:528:DC%2BD2cXisFyisbY%3D (Pubitemid 38716353)
37. D. Li J.T. McCann Y.N. Xia 2005 Use of electrospinning to directly fabricate hollow nanofibers with functionalized inner and outer surfaces Small 1 1 83 86 10.1002/smll.200400056 1:CAS:528:DC%2BD2cXhtVKhtrvN (Pubitemid 43951809)
38. D. Li A. Babel S.A. Jenekhe Y.N. Xia 2004 Nanofibers of conjugated polymers prepared by electrospinning with a two-capillary spinneret Adv Mater 16 22 2062 2066 10.1002/adma.200400606 1:CAS:528:DC%2BD2MXmslKr (Pubitemid 40079414)
39. J.T. McCann M. Marquez Y.N. Xia 2006 Melt coaxial electrospinning: A versatile method for the encapsulation of solid materials and fabrication of phase change nanofibers Nano Lett 6 12 2868 2872 10.1021/nl0620839 1:CAS:528:DC%2BD28XhtFyntbnO (Pubitemid 46129585)
40. A. Babel D. Li Y.N. Xia S.A. Jenekhe 2005 Electrospun nanofibers of blends of conjugated polymers: morphology, optical properties, and field-effect transistors Macromolecules 38 11 4705 4711 10.1021/ma047529r 1:CAS:528:DC%2BD2MXjsFymtbo%3D (Pubitemid 40795243)
41. Z.C. Sun E. Zussman A.L. Yarin J.H. Wendorff A. Greiner 2003 Compound core-shell polymer nanofibers by co-electrospinning Adv Mater 15 22 1929 1932 10.1002/adma.200305136 1:CAS:528:DC%2BD3sXps1emsb4%3D
42. J.H. Yu S.V. Fridrikh G.C. Rutledge 2004 Production of submicrometer diameter fibers by two-fluid electrospinning Adv Mater 16 17 1562 1566 10.1002/adma.200306644 1:CAS:528:DC%2BD2cXovVymt7k%3D
43. I.G. Loscertales A. Barrero I. Guerrero R. Cortijo M. Marquez A.M. Gaňán-Calvo 2002 Micro/nano encapsulation via electrified coaxial liquid jets Science 295 5560 1695 1698 10.1126/science.1067595 1:CAS:528:DC%2BD38Xhsleiu7w%3D (Pubitemid 34202901)
44. G. Larsen R. Velarde-Ortiz K. Minchow A. Barrero I.G. Loscertales 2003 A method for making inorganic and hybrid (organic/inorganic) fibers and vesicles with diameters in the submicrometer and micrometer range via sol-gel chemistry and electrically forced liquid jets J Am Chem Soc 125 5 1154 1155 10.1021/ja028983i 1:CAS:528:DC%2BD3sXhtlCktQ%3D%3D (Pubitemid 36159811)
45. I.G. Loscertales A. Barrero M. Márquez R. Spretz R. Velarde-Ortiz G. Larsen 2004 Electrically forced coaxial nanojets for one-step hollow nanofiber design J Am Chem Soc 126 17 5376 5377 10.1021/ja049443j 1:CAS:528:DC%2BD2cXivVansr0%3D (Pubitemid 38596347)
46. G.H. Kim T.J. Min S.A. Park W.D. Kim 2008 Coaxially electrospun micro/nanofibrous poly(ε-caprolactone)/eggshell-protein scaffold Bioinsp Biomim 3 1 016006 10.1088/1748-3182/3/1/016006 (Pubitemid 351433068)
47. X.Q. Li Y. Su R. Chen C.L. He H.S. Wang X.M. Mo 2009 Fabrication and properties of core-shell structure P(LLA-CL) nanofibers by coaxial electrospinning J Appl Polym Sci 111 3 1564 1570 10.1002/app.29056 1:CAS:528:DC%2BD1cXhsFemtrvO
48. J.C. Di H.Y. Chen X.F. Wang Y. Zhao L. Jiang J.H. Yu R.R. Xu 2008 Fabrication of zeolite hollow fibers by coaxial electrospinning Chem Mater 20 11 3543 3545 10.1021/cm8006809 1:CAS:528:DC%2BD1cXlslOisbs%3D
49. G. Kwak G.H. Lee S.H. Shim K.B. Yoon 2008 Fabrication of light-guiding core/sheath fibers by coaxial electrospinning Macromol Rapid Comm 29 10 815 820 10.1002/marc.200800065 1:CAS:528:DC%2BD1cXntFWlsr4%3D
50. Y.Z. Zhang Z.M. Huang X.J. Xu C.T. Lim S. Ramakrishna 2004 Preparation of core-shell structured PCL-r-gelatin bi-component nanofibers by coaxial electrospinning Chem Mater 16 18 3406 3409 10.1021/cm049580f 1:CAS:528:DC%2BD2cXmsVGqtLw%3D
51. C.C. Kuo C.T. Wang W.C. Chen 2009 Poly(3-hexylthiophene)/poly(methyl methacrylate) core-shell electrospun fibers for sensory applications Macromol Symp 279 1 41 47 10.1002/masy.200950506 1:CAS:528:DC%2BD1MXot1aksbg%3D
52. C.L. He Z.M. Huang X.J. Han 2009 Fabrication of drug-loaded electrospun aligned fibrous threads for suture applications J Biomed Mater Res 89A 1 80 95 10.1002/jbm.a.32004 1:CAS:528:DC%2BD1MXjsVahurg%3D
53. X.J. Han Z.M. Huang C.L. He L. Liu Q.S. Wu 2006 Coaxial electrospinning of PC(shell)/PU(core) composite nanofibers for textile application Polym Compos 27 4 381 387 10.1002/pc.20194 1:CAS:528:DC%2BD28XnsVOks7g%3D (Pubitemid 44186733)
54. S. Arumuganathar S.N. Jayasinghe 2007 Pressure assisted spinning: A versatile and economical direct fibre to scaffold spinning methodology Macromol Rapid Comm 28 14 1491 1496 10.1002/marc.200700153 1:CAS:528:DC%2BD2sXosVOisbw%3D (Pubitemid 47167404)
55. S. Arumuganathar S.N. Jayasinghe 2007 A novel direct fibre generation technique for preparing functionalized and compound scaffolds and membranes for applications within the life sciences Biomed Mater 2 3 189 195 10.1088/1748-6041/2/3/004 1:CAS:528:DC%2BD2sXht1Glsr%2FN (Pubitemid 47354093)
56. Q. Zhao Y. Xin Z.H. Huang S.D. Liu C.H. Yang Y.F. Li 2007 Using poly[2-methoxy-5-(2′-ethyl-hexyloxy)-1,4-phenylene vinylene] as shell to fabricate the highly fluorescent nanofibers by coaxial electrospinning Polymer 48 15 4311 4315 10.1016/j.polymer.2007.04.068 1:CAS:528:DC%2BD2sXnsVKmtbg%3D (Pubitemid 47017347)
57. J.E. DÍaz A. Barrero M. Márquez I.G. Loscertales 2006 Controlled encapsulation of hydrophobic liquids in hydrophilic polymer nanofibers by co-electrospinning Adv Funct Mater 16 16 2110 2116 10.1002/adfm.200600204 (Pubitemid 44672579)
58. G. Larsen R. Spretz R. Velarde-Ortiz 2004 Use of coaxial gas jackets to stablilize Taylor cone of volatile solutions and to induce particle-to-fiber transitions Adv Mater 16 2 166 169 10.1002/adma.200306021 1:CAS:528: DC%2BD2cXhtlWgu7g%3D
59. S.L. Chen H.Q. Hou P. Hu J.H. Wendorff A. Greiner S. Agarwal 2009 Polymeric nanosprings by bicomponent electrospinning Macromol Mater Eng 294 4 265 271 10.1002/mame.200800342 1:CAS:528:DC%2BD1MXlsFSrs78%3D
60. A. Arinstein R. Avrahami E. Zussman 2009 Buckling behaviour of electrospun microtubes: A simple theoretical model and experimental observations J Phys D-Appl Phys 42 1 015507 10.1088/0022-3727/42/1/015507
61. J.M. López-Herrera A. Barrero A. López I.G. Loscertales M. Márquez 2003 Coaxial jets generated from electrified Taylor cones. Scaling laws J Aerosol Sci 34 5 535 552 10.1016/S0021-8502(03)00021-1 (Pubitemid 38352542)
62. Y.Y. Hu Z.M. Huang 2007 Numerical study on two-phase flow patterns in coaxial electrospinning J Appl Phys 101 8 084307 10.1063/1.2717605 (Pubitemid 46691165)
63. K.H.K. Chan M. Kotaki 2009 Fabrication and morphology control of poly(methyl methacrylate) hollow structures via coaxial electrospinning J Appl Polym Sci 111 1 408 416 10.1002/app.28994 1:CAS:528:DC%2BD1cXhsVGmurzK
64. X.L. Xu L.X. Yang X.Y. Xu X. Wang X.S. Chen Q.Z. Liang J. Zeng X.B. Jing 2005 Ultrafine medicated fibers electrospun from W/O emulsions J Control Release 108 1 33 42 10.1016/j.jconrel.2005.07.021 1:CAS:528:DC%2BD2MXhtFaktrzK (Pubitemid 41476672)
65. X.L. Xu X.L. Zhuang X.S. Chen X.R. Wang L.X. Yang X.B. Jing 2006 Preparation of core-sheath composite nanofibers by emulsion electrospinning Macromol Rapid Comm 27 19 1637 1642 10.1002/marc.200600384 1:CAS:528: DC%2BD28XhtFars7%2FK (Pubitemid 44580547)
66. X.L. Xu X.S. Chen P.A. Ma X.R. Wang X.B. Jing 2008 The release behavior of doxorubicin hydrochloride from medicated fibers prepared by emulsion-electrospinning Eur J Pharm Biopharm 70 1 165 170 10.1016/j.ejpb.2008. 03.010 1:CAS:528:DC%2BD1cXhtVOitrjO
67. X.L. Xu X.S. Chen Z.F. Wang X.B. Jing 2009 Ultrafine PEG-PLA fibers loaded with both paclitaxel and doxorubicin hydrochloride and their in vitro cytotoxicity Eur J Pharm Biopharm 72 1 18 25 10.1016/j.ejpb.2008.10.015 1:CAS:528:DC%2BD1MXjvVOqsbc%3D
68. Y. Su X.Q. Li S.P. Liu X.M. Mo S. Ramakrishna 2009 Controlled release of dual drugs from emulsion electrospun nanofibrous mats Colloid Surface B 73 2 376 381 10.1016/j.colsurfb.2009.06.009 1:CAS:528:DC%2BD1MXhtVSnur3N
69. Y. Yang X.H. Li W.G. Cui S.B. Zhou R. Tan C.Y. Wang 2008 Structural stability and release profiles of proteins from core-shell poly(dl-lactide) ultrafine fibers prepared by emulsion electrospinning J Biomed Mater Res 86A 2 374 385 10.1002/jbm.a.31595 1:CAS:528:DC%2BD1cXosFWmt78%3D (Pubitemid 351969635)
70. Y. Yang X.H. Li M.B. Qi S.B. Zhou J. Weng 2008 Release pattern and structural integrity of lysozyme encapsulated in core-sheath structured poly(dl-lactide) ultrafine fibers prepared by emulsion electrospinning Eur J Pharm Biopharm 69 1 106 116 10.1016/j.ejpb.2007.10.016 1:CAS:528: DC%2BD1cXktlGlt7o%3D
71. S.Y. Chew J. Wen E.K.F. Yim K.W. Leong 2005 Sustained release of proteins from electrospun biodegradable fibers Biomacromolecules 6 4 2017 2024 10.1021/bm0501149 1:CAS:528:DC%2BD2MXjvVeiu7Y%3D (Pubitemid 41052194)
72. X.Q. Li Y. Su X. Zhou X.M. Mo 2009 Distribution of sorbitan monooleate in poly(l-lactide-co-ε-caprolactone) nanofibers from emulsion electrospinning Colloid Surface B 69 2 221 224 10.1016/j.colsurfb.2008.11.031 1:CAS:528:DC%2BD1MXisFGktrg%3D
73. Y.L. Liao L.F. Zhang Y. Gao Z.T. Zhu H. Fong 2008 Preparation, characterization, and encapsulation/release studies of a composite nanofiber mat electrospun from an emulsion containing poly(lactic-co-glycolic acid) Polymer 49 24 294 5299 10.1016/j.polymer.2008.09.045
74. X.R. Li H. Zhang H. Li G.W. Tang Y.H. Zhao X.Y. Yuan 2008 Self-accelerated biodegradation of electrospun poly(ethylene glycol)-poly(l-lactide) membranes by loading proteinase K Polym Degrad Stab 93 3 618 626 10.1016/j.polymdegradstab.2008.01.003 1:CAS:528:DC%2BD1cXjt1Gnt7c%3D
75. M. Angeles H.L. Cheng S.S. Velankar 2008 Emulsion electrospinning: composite fibers from drop breakup during electrospinning Polym Adv Technol 19 7 728 733 10.1002/pat.1031 1:CAS:528:DC%2BD1cXpsVWrsbk%3D
76. A.V. Bazilevsky A.L. Yarin C.M. Megaridis 2007 Co-electrospinning of core-shell fibers using a single-nozzle technique Langmuir 23 5 2311 2314 10.1021/la063194q 1:CAS:528:DC%2BD2sXhtVyntbc%3D (Pubitemid 46383641)
77. M. Wei J. Lee B. Kang J. Mead 2005 Preparation of core-sheath nanofibers from conducting polymer blends Macromol Rapid Comm 26 14 1127 1132 10.1002/marc.200500212 1:CAS:528:DC%2BD2MXntVeju7o%3D (Pubitemid 41092870)
78. M. Wei B. Kang C. Sung J. Mead 2006 Core-sheath structure in electrospun nanofibers from polymer blends Macromol Mater Eng 291 11 1307 1314 10.1002/mame.200600284 1:CAS:528:DC%2BD28XhtlSisrzJ (Pubitemid 44892785)
79. X.H. Li C.L. Shao Y.C. Liu 2007 A simple method for controllable preparation of polymer nanotubes via a single capillary electrospinning Langmuir 23 22 10920 10923 10.1021/la701806f 1:CAS:528:DC%2BD2sXhtVGmtbfJ (Pubitemid 350069306)
80. C.C. Kuo C.T. Wang W.C. Chen 2008 Highly-aligned electrospun luminescent nanofibers prepared from polyfluorene/PMMA blends: fabrication, morphology, photophysical properties and sensory applications Macromol Mater Eng 293 12 999 1008 10.1002/mame.200800224 1:CAS:528:DC%2BD1MXhsVCgtA%3D%3D
81. H.N. Na X.W. Liu H. Sun Y.H. Zhao C. Zhao X.Y. Yuan 2010 Electrospinning of ultrafine PVDF/PC fibers from their dispersed solutions J Polym Sci B-Polym Phys 48 3 372 380 10.1002/polb.21899 1:CAS:528:DC%2BD1MXhs1WjtL7E
82. H.N. Na X.W. Liu J.Q. Li Y.H. Zhao C. Zhao X.Y. Yuan 2009 Formation of core/shell ultrafine fibers of PVDF/PC by electrospinning via introduction of PMMA or BTEAC Polymer 50 26 6340 6349 10.1016/j.polymer.2009.10.061 1:CAS:528:DC%2BD1MXhsFWlt7bL
83. C.L. He Z.M. Huang X.J. Han L. Liu H.S. Zhang L.S. Chen 2006 Coaxial electrospun poly(l-lactic acid) ultrafine fiber for sustained drug delivery J Macromol Sci-Phys 45 4 515 524 10.1080/00222340600769832 1:CAS:528: DC%2BD28Xnslamur8%3D (Pubitemid 43982561)
84. H.L. Jiang Y.Q. Hu P.C. Zhao Y. Li K.J. Zhu 2006 Modulation of protein release from biodegradable core-shell structured fibers prepared by coaxial electrospinning J Biomed Mater Res 79B 1 50 57 10.1002/jbm.b.30510 1:CAS:528:DC%2BD28XhtVCksbnM (Pubitemid 44477473)
85. E. Jo S. Lee K.T. Kim Y.S. Won H.-S. Kim E.C. Cho U. Jeong 2009 Coresheath nanofibers containing colloidal arrays in the core for programmable multi-agent delivery Adv Mater 21 9 968 972 10.1002/adma.200802948 1:CAS:528:DC%2BD1MXjsVajs7o%3D
86. H.X. Qi P. Hu J. Xu A.J. Wang 2006 Encapsulation of drug reservoirs in fibers by emulsion electrospinning: morphology characterization and preliminary release assessment Biomacromolecules 7 8 2327 2330 10.1021/bm060264z 1:CAS:528:DC%2BD28XmvF2mtrg%3D (Pubitemid 44336343)
87. H.M. Nie B.W. Soh Y.-C. Fu C.-H. Wang 2008 Three-dimensional fibrous PLGA/HAp composite scaffold for BMP-2 delivery Biotechnology and Bioengineering. Biotechnol Bioeng 99 1 223 234 10.1002/bit.21517 1:CAS:528:DC%2BD2sXhsVOrsLnI
88. S. Arumuganathar S. Irvine J.R. McEwan S.N. Jayasinghe 2008 A novel direct aerodynamically assisted threading methodology for generating biologically viable microthreads encapsulating living primary cells J Appl Polym Sci 107 2 1215 1225 10.1002/app.27190 1:CAS:528:DC%2BD2sXhtlWmtrnM (Pubitemid 350241687)
89. F. Yi D.A. LaVan 2008 Poly(glycerol sebacate) nanofiber scaffolds by core/shell electrospinning Macromol Biosci 8 9 803 806 10.1002/mabi.200800041 1:CAS:528:DC%2BD1cXhtFKnurzM
90. S. Li B. Sun X.R. Li X.Y. Yuan 2008 Characterization of electrospun core/shell poly(vinyl pyrrolidone)/poly(l-lactide-co-epsilon-caprolactone) fibrous membranes and their cytocompatibility in vitro J Biomat Sci-Polym Ed 19 2 245 258 10.1163/156856208783432499
91. Li H, Zhao CG, Wang ZX, Zhang H, Yuan XY, Kong D L. Controlled release of PDGF-bb by coaxial electrospun dextran/Poly (l-lactide-co-ε-caprolactone) fibers with an ultrafine core/shell structure. J Biomat Sci-Polym Ed, DOI: 10.1163/156856209X445302
92. I.C. Liao S.Y. Chew K.W. Leong 2006 Aligned core-shell nanofibers delivering bioactive proteins Nanomedicine 1 4 465 471 10.2217/17435889.1.4.465 1:CAS:528:DC%2BD2sXhsV2htbo%3D
93. Y.C. Fu H.M. Nie M.L. Ho C.K. Wang C.H. Wang 2008 Optimized bone regeneration based on sustained release from three-dimensional fibrous PLGA/Hap composite scaffolds loaded with BMP-2 Biotechnol Bioeng 99 4 996 1006 10.1002/bit.21648 1:CAS:528:DC%2BD1cXit1Kqs7s%3D (Pubitemid 351316641)
94. Y.K. Luu K. Kim B.S. Hsiao B. Chu M. Hadjiargyrou 2003 Development of a nanostructured DNA delivery scaffold via electrospinning of PLGA and PLA-PEG block copolymers J Control Release 89 2 341 353 10.1016/S0168-3659(03)00097-X 1:CAS:528:DC%2BD3sXjtVegu7w%3D (Pubitemid 36507026)
95. D.H. Liang Y.K. Luu K. Kim B.S. Hsiao M. Hadjiargyrou B. Chu 2005 In vitro non-viral gene delivery with nanofibrous scaffolds Nucleic Acids Res 33 19 e170 10.1093/nar/gni171 (Pubitemid 41748059)
96. H.L. Jiang P.C. Zhao K.J. Zhu 2007 Fabrication and characterization of zein-based nanofibrous scaffolds by an electrospinning method Macromol Biosci 7 4 517 525 10.1002/mabi.200600277 1:CAS:528:DC%2BD2sXkvV2itLc%3D (Pubitemid 47237529)
97. M. Wang J.H. Yu D.L. Kaplan G.C. Rutledge 2006 Production of submicron diameter silk fibers under benign processing conditions by two-fluid electrospinning Macromolecules 39 3 1102 1107 10.1021/ma0517749 1:CAS:528:DC%2BD28XisVyjuw%3D%3D (Pubitemid 43235666)