메뉴 건너뛰기




Volumn 655, Issue , 2009, Pages 171-188

Immune modulators with defined molecular targets: Cornerstone to optimize rational vaccine design

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; B7 ANTIGEN; BACTERIAL TOXIN; CD134 ANTIGEN; CD1D ANTIGEN; CD28 ANTIGEN; CD40 ANTIGEN; CHOLERA TOXIN; CYCLIC GMP; CYTOKINE; ESCHERICHIA COLI ENTEROTOXIN; FREUND ADJUVANT; IMIQUIMOD; IMMUNOLOGICAL ADJUVANT; IMMUNOMODULATING AGENT; INFLUENZA VIRUS HEMAGGLUTININ; INTERLEUKIN 12; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST; ANTIGEN; IMMUNOLOGIC FACTOR; LIGAND; SUBUNIT VACCINE; TOLL LIKE RECEPTOR; VACCINE;

EID: 77955495956     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-1132-2_13     Document Type: Article
Times cited : (8)

References (158)
  • 1
    • 0242580118 scopus 로고    scopus 로고
    • Cutting Edge: Different Toll-Like Receptor Agonists Instruct Dendritic Cells to Induce Distinct Th Responses via Differential Modulation of Extracellular Signal-Regulated Kinase-Mitogen-Activated Protein Kinase and c-Fos
    • Agrawal S. Agrawal A. Doughty B et al. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen, activated protein kinase and c-Fos,J Immunol 2003; 171(10):4984-9. (Pubitemid 37432777)
    • (2003) Journal of Immunology , vol.171 , Issue.10 , pp. 4984-4989
    • Agrawal, S.1    Agrawal, A.2    Doughty, B.3    Gerwitz, A.4    Blenis, J.5    Van Dyke, T.6    Pulendran, B.7
  • 2
    • 1242284156 scopus 로고    scopus 로고
    • Innate immunity via Toll-like receptors and Nod proteins
    • DOI 10.1016/j.mib.2003.12.013
    • Athman R. Philpott D. Innate immunity via Toll-like receptors and Nod proteins . Cure Opin Microbiol 2004 ; 7(1) :25-32. (Pubitemid 38223951)
    • (2004) Current Opinion in Microbiology , vol.7 , Issue.1 , pp. 25-32
    • Athman, R.1    Philpott, D.2
  • 3
    • 27644434075 scopus 로고    scopus 로고
    • Peptidoglycan recognition in innate immunity
    • DOI 10.1179/096805105X67256
    • Dziarski R. Gupta D. Peptidoglycan recognition in innate immunity. J Endotoxin Res 2005: 11(5) :304-10. (Pubitemid 41556039)
    • (2005) Journal of Endotoxin Research , vol.11 , Issue.5 , pp. 304-310
    • Dziarski, R.1    Gupta, D.2
  • 4
    • 33746028777 scopus 로고    scopus 로고
    • Intracellular pattern recognition receptors in the host response
    • DOI 10.1038/nature04946, PII NATURE04946
    • Meylan E. Tschopp J, Karin M. Intracellular pattern recognition receptors in the host response. Nature 2006: 442(7098):39-44. (Pubitemid 44064203)
    • (2006) Nature , vol.442 , Issue.7098 , pp. 39-44
    • Meylan, E.1    Tschopp, J.2    Karin, M.3
  • 5
    • 33845478357 scopus 로고    scopus 로고
    • The inflammatory caspases: Guardians against infections and sepsis
    • DOI 10.1038/sj.cdd.4402026, PII 4402026
    • Scott AM, Saleh M. The inllammatory caspases: guardians against infections and sepsis. Cell Death Differ 2007: 14(1):23-31. (Pubitemid 44911891)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.1 , pp. 23-31
    • Scott, A.M.1    Saleh, M.2
  • 6
    • 0014043852 scopus 로고
    • Vitro studies of immunological responses of lymphoid cells
    • Dutton RW. In vitro studies of immunological responses of lymphoid cells. Adv Immunol 1967: 6:253-336.
    • (1967) Adv Immunol , vol.6 , pp. 253-336
    • Dutton, R.W.1
  • 7
    • 0014322982 scopus 로고
    • The immune response of mice to antigen in macrophages
    • Unanue ER. Askonas BA. The immune response of mice to antigen in macrophages. Immunology 1968; 15(2):287-96.
    • (1968) Immunology , vol.15 , Issue.2 , pp. 287-296
    • Unanue, E.R.1    Askonas, B.A.2
  • 13
    • 33645218007 scopus 로고    scopus 로고
    • Novel human polysaccharide adjuvants with dual Th1 and Th2 potentiating activity
    • Petrovsky N. Novel human polysaccharide adjuvants with dual Th1 and Th2 potentiating activity. Vaccine 2006: 24 Suppl. 2:S226-9.
    • (2006) Vaccine , vol.24 , Issue.SUPPL. 2
    • Petrovsky, N.1
  • 14
    • 0029177443 scopus 로고
    • MF59. Design and evaluation of a safe and potent adjuvant for human vaccines
    • Ott G. Barchfeld GL. Chernoff D et al. MF59. Design and evaluation of a safe and potent adjuvant for human vaccines. Pharm Biotechnol 1995; 6:277-96.
    • (1995) Pharm Biotechnol , vol.6 , pp. 277-296
    • Ott, G.1    Barchfeld, G.L.2    Chernoff, D.3
  • 15
    • 0038330442 scopus 로고    scopus 로고
    • MF59-adjuvanted vaccines: Increased immunogenicity with an optimal safety profile
    • Podda A. Del Giudice G. MF59-adjuvanted vaccines: increased immunogenicity with an optimal safety profile. Expert Rev Vaccines 2003: 2(2):197-203.
    • (2003) Expert Rev Vaccines , vol.2 , Issue.2 , pp. 197-203
    • Podda, A.1    Del Giudice, G.2
  • 16
    • 33845874634 scopus 로고    scopus 로고
    • Pollinex Quattro: A novel and well-tolerated, ultra short-course allergy vaccine
    • DOI 10.1586/14760584.5.5.617
    • Patel P, Salapatek AM. Pollinex Qattro: a novel and well-tolerated, ultra short-course allergy vaccine. Expert Rev Vaccines 2006: 5(5) :617-29. (Pubitemid 46021044)
    • (2006) Expert Review of Vaccines , vol.5 , Issue.5 , pp. 617-629
    • Patel, P.1    Salapatek, A.M.F.2
  • 17
    • 34247234090 scopus 로고    scopus 로고
    • New hepatitis B vaccine formulated with an improved adjuvant system
    • DOI 10.1586/14760584.6.2.133
    • Kundi M. New hepatitis B vaccine formulated with an improved adjuvant system. Expert Rev Vaccines 2007: 6(2) :133-40. (Pubitemid 46607449)
    • (2007) Expert Review of Vaccines , vol.6 , Issue.2 , pp. 133-140
    • Kundi, M.1
  • 18
    • 0036789814 scopus 로고    scopus 로고
    • Taking toll: Lipid A mimetics as adjuvants and immunomodulators
    • Persing DH. Coler RN. Lacy MJ et al. Taking toll: lipid A mimetics as adjuvants and immunomodulators. Trends Microbiol 2002: 10(10 Suppl):S32-7.
    • (2002) Trends Microbiol , vol.10 , Issue.10 SUPPL.
    • Persing, D.H.1    Coler, R.N.2    Lacy, M.J.3
  • 19
    • 0019604334 scopus 로고
    • A fluorimetric method for the estimation of the critical micelle concentration of surfactants
    • De Vendittis E. Palumbo G. Parlato G et al. A fluorimetric method for the estimation of the critical micelle concentration of surfactants. Anal Biochem 1981: 115(2) :278-86.
    • (1981) Anal Biochem , vol.115 , Issue.2 , pp. 278-286
    • De Vendittis, E.1    Palumbo, G.2    Parlato, G.3
  • 20
    • 7044263390 scopus 로고    scopus 로고
    • Vaccine adjuvants: Current state and future trends
    • DOI 10.1111/j.0818-9641.2004.01272.x
    • Petrovsky N. Aguilar JC. Vaccine adjuvants: current state and future trends. Immunol Cell Biol 2004; 82(5) :488-96. (Pubitemid 39421058)
    • (2004) Immunology and Cell Biology , vol.82 , Issue.5 , pp. 488-496
    • Petrovsky, N.1    Aguilar, J.C.2
  • 22
    • 9444228872 scopus 로고    scopus 로고
    • Challenges facing adjuvants for cancer immunotherapy
    • DOI 10.1111/j.0818-9641.2004.01279.x
    • Mesa C. Fernandez LE. Challenges facing adjuvants for cancer immunotherapy. Immunol Cell Biol 2004: 82(6) :644-50. (Pubitemid 39563965)
    • (2004) Immunology and Cell Biology , vol.82 , Issue.6 , pp. 644-650
    • Mesa, C.1    Fernandez, L.E.2
  • 23
    • 0031062313 scopus 로고    scopus 로고
    • Recent advances in vaccine adjuvants: The development of MF59 emulsion and polymeric microparticles
    • DOI 10.1016/S1357-4310(96)10058-7, PII S1357431096100587
    • O'Hagan DT, Ott GS, Van Nest G. Recent advances in vaccine adjuvants: the development of MF59 emulsion and polymeric microparticles. Mol Med Today 1997: 3(2):69-75. (Pubitemid 28095801)
    • (1997) Molecular Medicine Today , vol.3 , Issue.2 , pp. 69-75
    • O'Hagan, D.T.1    Ott, G.S.2    Van Nest, G.3
  • 25
    • 85044700671 scopus 로고    scopus 로고
    • Recent advances in vaccine adjuvants for systemic and mucosal administration
    • O'Hagan DT. Recent advances in vaccine adjuvants for systemic and mucosal administration. J Pharm Pharmacol 1998: 50(1) :1-10.
    • (1998) J Pharm Pharmacol , vol.50 , Issue.1 , pp. 1-10
    • O'Hagan, D.T.1
  • 26
    • 2942606120 scopus 로고    scopus 로고
    • Autoimmunity induced by adjuvant hydrocarbon oil components of vaccine
    • DOI 10.1016/j.biopha.2004.04.009, PII S0753332204000642
    • Kuroda Y, Nacionales DC. Akaogi J et al. Autoimmunity induced by adjuvant hydrocarbon oil components of vaccine. Biomed Pharrnacother 2004; 58(5) :325-37. (Pubitemid 38759732)
    • (2004) Biomedicine and Pharmacotherapy , vol.58 , Issue.5 , pp. 325-337
    • Kuroda, Y.1    Nacionales, D.C.2    Akaogi, J.3    Reeves, W.H.4    Satoh, M.5
  • 27
    • 0033774038 scopus 로고    scopus 로고
    • Safety of allergen-specific immunotherapy, Relation between dosage regimen, allergen extract, disease and systemic side-effects during induction treatment
    • Mellerup MT. Hahn GW, Poulsen LK et al. Safety of allergen-specific immunotherapy, Relation between dosage regimen, allergen extract, disease and systemic side-effects during induction treatment. Clin Exp Allergy 2000; 30(10) :1423-9.
    • (2000) Clin Exp Allergy , vol.30 , Issue.10 , pp. 1423-1429
    • Mellerup, M.T.1    Hahn, G.W.2    Poulsen, L.K.3
  • 28
    • 0027479512 scopus 로고
    • How safe is 1% alum irrigation in controlling intractable vesical hemorrhage?
    • Goswami AK. Mahajan RK. Nath R et al. How safe is 1% alum irrigation in controlling intractable vesical hemorrhage ? J Urol 1993; 149(2):264-7. (Pubitemid 23097569)
    • (1993) Journal of Urology , vol.149 , Issue.2 , pp. 264-267
    • Goswami, A.K.1    Mahajan, R.K.2    Nath, R.3    Sharma, S.K.4
  • 30
    • 4043130309 scopus 로고    scopus 로고
    • 59-adjuvanted subunit vaccine and a virosome-based subunit vaccine in elderly
    • Ruf BR. Colberg K, Frick M et al. Open, randomized study to compare the immunogenicity and reactogenicity of an influenza split vaccine with an MF59-adjuvanted subunit vaccine and a virosome-based subunit vaccine in elderly. Infection 2004: 32(4) :191-8. (Pubitemid 39070597)
    • (2004) Infection , vol.32 , Issue.4 , pp. 191-198
    • Ruf, B.R.1    Colberg, K.2    Frick, M.3    Preusche, A.4
  • 31
    • 0033997899 scopus 로고    scopus 로고
    • CpG DNA induces stronger immune responses with less toxicity than other adjuvants
    • DOI 10.1016/S0264-410X(99)00526-5, PII S0264410X99005265
    • Weeratna RD, McCluskie MJ, XU Y et al. CpG DNA induces stronger immune responses with less toxicitythan other adjuvants. Vaccine 2000: 18(17):1755-62. (Pubitemid 30122837)
    • (2000) Vaccine , vol.18 , Issue.17 , pp. 1755-1762
    • Weeratna, R.D.1    McCluskie, M.J.2    Xu, Y.3    Davis, H.L.4
  • 32
    • 0037035853 scopus 로고    scopus 로고
    • A dilemma for mucosal vaccination: Efficacy versus toxicity using enterotoxin-based adjuvants
    • DOI 10.1016/S0264-410X(02)00155-X, PII S0264410X0200155X
    • Fujihashi K, Koga T, van Ginkd FW et al.A dilemma for mucosal vaccination: efficacy versus toxicity usingenterotoxin-based adjuvants. Vaccine 2002: 20(19-20):2431-8. (Pubitemid 34615580)
    • (2002) Vaccine , vol.20 , Issue.19-20 , pp. 2431-2438
    • Fujihashi, K.1    Koga, T.2    Van Ginkel, F.W.3    Hagiwara, Y.4    McGhee, J.R.5
  • 33
    • 0034327167 scopus 로고    scopus 로고
    • Cutting edge: The mucosal adjuvant choleratoxin redirects vaccine proteins into olfactory tissues
    • van Ginkd FW;Jackson RJ, Yuki Y et al. Cutting edge: the mucosal adjuvant choleratoxin redirects vaccine proteins into olfactory tissues. J Immunol 2000: 165(9):4778-82.
    • (2000) J Immunol , vol.165 , Issue.9 , pp. 4778-1782
    • Van Ginkd, F.W.1    Jackson, R.J.2    Yuki, Y.3
  • 35
    • 2442665183 scopus 로고    scopus 로고
    • Using imiquimod for genital warts in female patients
    • DOI 10.1089/154099904323016428
    • COX JT, Petry KU, Rylander E et al. Using imiquimod for genital warts in female patients. J Womens Health (Larchmt) 2004; 13(3):265-71. (Pubitemid 38660523)
    • (2004) Journal of Women's Health , vol.13 , Issue.3 , pp. 265-271
    • Cox, J.T.1    Petry, K.-U.2    Rylander, E.3    Roy, M.4
  • 37
    • 3042683348 scopus 로고    scopus 로고
    • Application of Quillaja saponaria extracts as oral adjuvants for plant-made vaccines
    • DOI 10.1517/14712598.4.6.947
    • Kirk DD, Rempel R, Pinkhasov J et al. Application of Quillaja saponaria extracts as oral adjuvants for plant-made vaccines. Expert Opin Biol Ther 2004: 4(6):947-58. (Pubitemid 38843231)
    • (2004) Expert Opinion on Biological Therapy , vol.4 , Issue.6 , pp. 947-958
    • Kirk, D.D.1    Rempel, R.2    Pinkhasov, J.3    Walmsley, A.M.4
  • 38
    • 0029176755 scopus 로고
    • Strucrural and immunological characterization of the vaccine adjuvant QS-21
    • Kensil CR, Wu JY, Soltysik S. Strucrural and immunological characterization of the vaccine adjuvant QS-21. Pharm Biotechnol 1995: 6:525-41.
    • (1995) Pharm Biotechnol , vol.6 , pp. 525-541
    • Kensil, C.R.1    Wu, J.Y.2    Soltysik, S.3
  • 41
    • 4043056554 scopus 로고    scopus 로고
    • Antigen delivery systems
    • DOI 10.1586/14760584.3.4.453
    • Kersten G, Hirschberg H. Antigen delivery systems. Expert Rev Vaccines 2004: 3(4):453-62. (Pubitemid 39061710)
    • (2004) Expert Review of Vaccines , vol.3 , Issue.4 , pp. 453-462
    • Kersten, G.1    Hirschberg, H.2
  • 43
    • 0037847495 scopus 로고    scopus 로고
    • Virosomal adjuvanted antigen delivery systems
    • DOI 10.1586/14760584.2.2.189
    • Moser C,, Metcalfe IC, Viret JF. Virosomal adjuvanted antigen delivery systems. Expert Rev Vaccines 2003; 2(2):189-96. (Pubitemid 36559924)
    • (2003) Expert Review of Vaccines , vol.2 , Issue.2 , pp. 189-196
    • Moser, C.1    Metcalfe, I.C.2    Viret, J.-F.3
  • 44
    • 9244234954 scopus 로고    scopus 로고
    • Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs
    • DOI 10.1016/j.copbio.2004.10.005, PII S0958166904001430
    • Felnerova D, Virec JF, Gluck R, et al.Liposomes and virosomes as delivery systems for antigens, nucleic acidsand drugs. Curr Opin Biotechnol 2004: 15(6):518-29. (Pubitemid 39551004)
    • (2004) Current Opinion in Biotechnology , vol.15 , Issue.6 , pp. 518-529
    • Felnerova, D.1    Viret, J.-F.2    Gluck, R.3    Moser, C.4
  • 45
    • 0036555140 scopus 로고    scopus 로고
    • Delivery of protein antigens to the immune system by fusion-active virosomes: A comparison with liposomes and ISCOMs
    • DOI 10.1023/A:1020198908574
    • Bungener L, Huckriede A, Wilschut J et al. Delivery of protein antigens to the immune system by fusion-active virosomes: a comparison with liposomes and ISCOMs. Biosci Rep 2002: 22(2):323-38. (Pubitemid 35222739)
    • (2002) Bioscience Reports , vol.22 , Issue.2 , pp. 323-338
    • Bungener, L.1    Huckriede, A.2    Wilschut, J.3    Daemen, T.4
  • 46
    • 24644505322 scopus 로고    scopus 로고
    • Adjuvant and antigen delivery properties of virosomes
    • DOI 10.2174/156720105774370302
    • Gluck R, Burri KG, Metcalfe I. Adjuvant and antigen delivery properties of virosomes, Curr Drug Deliv 2005: 2(4):395-400. (Pubitemid 41277771)
    • (2005) Current Drug Delivery , vol.2 , Issue.4 , pp. 395-400
    • Gluck, R.1    Burri, K.G.2    Metcalfe, I.3
  • 47
    • 0029868650 scopus 로고    scopus 로고
    • Adjuvant properties of montanide CSA 720 with a recombinant HIV P17 gag protein and synthetic peptide antigens
    • Kirkley JE, Goldstein AL, Naylor PH. Adjuvant propertiesof montanide CSA720 with a recombinant HIV P17 gagprotein and syntheticpeptide antigens. Scand J Immunol 1996: 43(4):431-8. (Pubitemid 26106154)
    • (1996) Scandinavian Journal of Immunology , vol.43 , Issue.4 , pp. 431-438
    • Kirkley, J.E.1    Goldstein, A.L.2    Naylor, P.H.3
  • 48
    • 33845702087 scopus 로고    scopus 로고
    • SEPPIC vaccine adjuvants for poultry
    • DOI 10.1196/annals.1373.024, Impact of Emerging Zoonotic Diseases on Animal Health: 8th Biennial Conference of the Society for Tropical Veterinary Medicine
    • Dupuis L, Ascarateil S, Aucoururier J et al. SEPPIC vaccine adjuvants for poultry.Ann NY Acad Sci 2006; 1081:202-5. (Pubitemid 44968774)
    • (2006) Annals of the New York Academy of Sciences , vol.1081 , pp. 202-205
    • Dupuis, L.1    Ascarateil, S.2    Aucouturier, J.3    Ganne, V.4
  • 49
    • 0038176089 scopus 로고    scopus 로고
    • Montanide ISA 720 and 51: A new generation of water in oil emulsions as adjuvants for human vaccines
    • DOI 10.1586/14760584.1.1.111
    • Aucoururier J, Dupuis L, Deville S et al. Monranide ISA 720 and 51: a new generation of water in oil emulsions as adjuvants for human vaccines. Expert Rev Vaccines 2002: 1(1):111-8. (Pubitemid 36686885)
    • (2002) Expert Review of Vaccines , vol.1 , Issue.1 , pp. 111-118
    • Aucouturier, J.1    Dupuis, L.2    Deville, S.3    Ascarateil, S.4    Ganne, V.5
  • 50
    • 2942534189 scopus 로고    scopus 로고
    • CEL-1000 - A peptide with adjuvant activity for Th1 immune responses
    • DOI 10.1016/j.vaccine.2003.11.062, PII S0264410X04002427, Modern Vaccine Adjuvants and Delivery Systems
    • Charoenvit Y, Goel N, Whelan M et al. CEL-l000-a peptide with adjuvant activity for Th1 immune responses. Vaccine 2004; 22(19):2368-73. (Pubitemid 38757331)
    • (2004) Vaccine , vol.22 , Issue.19 , pp. 2368-2373
    • Charoenvit, Y.1    Goel, N.2    Whelan, M.3    Rosenthal, K.S.4    Zimmerman, D.H.5
  • 52
    • 0141625693 scopus 로고    scopus 로고
    • Genes to genetic immunization: Identification of bacterial vaccine candidates
    • DOI 10.1016/S1046-2023(03)00133-6
    • Allan E, Wren BW Genes to genetic immunization: identification of bacterial vaccine candidates. Methods 2003; 31(3):193-8. (Pubitemid 37162791)
    • (2003) Methods , vol.31 , Issue.3 , pp. 193-198
    • Allan, E.1    Wren, B.W.2
  • 53
    • 0035342306 scopus 로고    scopus 로고
    • New drug targets for genomic cancer therapy: Successes, limitations, opportunities and future challenges
    • Workman P. New drug targets for genomic cancer therapy: successes, limitations, opportunities and future challenges. Cure Cancer Drug Targets 2001: 1(1):33-47. (Pubitemid 33772173)
    • (2001) Current Cancer Drug Targets , vol.1 , Issue.1 , pp. 33-47
    • Workman, P.1
  • 56
    • 30544448127 scopus 로고    scopus 로고
    • Triggering TLR signaling in vaccination
    • DOI 10.1016/j.it.2005.11.005, PII S1471490605002863
    • van Duin D, Medzhitov R, Shaw AC. Triggering TLR signaling in vaccination. Trends Immunol 2006: 27(1):49-55. (Pubitemid 43083564)
    • (2006) Trends in Immunology , vol.27 , Issue.1 , pp. 49-55
    • Van Duin, D.1    Medzhitov, R.2    Shaw, A.C.3
  • 57
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006: 124(4):783-801. (Pubitemid 43261452)
    • (2006) Cell , vol.124 , Issue.4 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 59
    • 29444441343 scopus 로고    scopus 로고
    • Manifold mechanisms of toll-like receptor-ligand recognition
    • DOI 10.1007/s10875-005-7829-1
    • Ishii KJ, Coban C, Akira S. Manifold mechanisms of toll-like receptor-ligand recognition. J Clin Immunol 2005; 25(6):511-21. (Pubitemid 43011743)
    • (2005) Journal of Clinical Immunology , vol.25 , Issue.6 , pp. 511-521
    • Ishii, K.J.1    Coban, C.2    Akira, S.3
  • 60
    • 1542407034 scopus 로고    scopus 로고
    • Airway peptidoglycan and immunostimulatory DNA exposures have divergent effects on the development of airway allergen hypersensitivities
    • DOI 10.1016/j.jaci.2003.12.011
    • Chisholm D, Libet L, Hayashi T et al. Airway peptidoglycan and immunostimulatory DNA exposures have divergent effects on the development of airway allergen hypersensitivities. J Allergy Clin Immunol 2004; 113(3):448-54. (Pubitemid 38338949)
    • (2004) Journal of Allergy and Clinical Immunology , vol.113 , Issue.3 , pp. 448-454
    • Chisholm, D.1    Libet, L.2    Hayashi, T.3    Horner, A.A.4
  • 61
    • 33646190155 scopus 로고    scopus 로고
    • Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy
    • Johansen P, Senti G, Martinez Gomez JM et al. Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy. Clin Exp Allergy 2005: 35(12):1591-8.
    • (2005) Clin Exp Allergy , vol.35 , Issue.12 , pp. 1591-1518
    • Johansen, P.1    Senti, G.2    Martinez Gomez, J.M.3
  • 63
    • 0038282518 scopus 로고    scopus 로고
    • Toll-like receptors and T-helper-1/T-helper-2 responses
    • Dabbagh K, Lewis DB. Toll-like receptors and T-helper-1/T-helper-2 responses. Curr Opin Infect Dis 2003; 16(3):199-204. (Pubitemid 36677312)
    • (2003) Current Opinion in Infectious Diseases , vol.16 , Issue.3 , pp. 199-204
    • Dabbagh, K.1    Lewis, D.B.2
  • 64
    • 3042550183 scopus 로고    scopus 로고
    • Toll-like receptors and immune response in allergic disease
    • DOI 10.1385/CRIAI:26:2:115
    • Gangloff SC, Guenounou M. Toll-like receptors and immune response in allergic disease. Clin Rev Allergy Immunol 2004; 26(2) :115-25. (Pubitemid 38813592)
    • (2004) Clinical Reviews in Allergy and Immunology , vol.26 , Issue.2 , pp. 115-125
    • Gangloff, S.C.1    Guenounou, M.2
  • 65
    • 20444393509 scopus 로고    scopus 로고
    • TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells
    • Patel M, Xu D, Kewin P et al. TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T-cells. J Immunol 2005; 174(12):7558-63. (Pubitemid 40806259)
    • (2005) Journal of Immunology , vol.174 , Issue.12 , pp. 7558-7563
    • Patel, M.1    Xu, D.2    Kewin, P.3    Choo-Kang, B.4    McSharry, C.5    Thomson, N.C.6    Liew, F.Y.7
  • 66
    • 33646487278 scopus 로고    scopus 로고
    • Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulator y T-cells
    • Liu H, Komai-Koma M, Xu D et al. Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulator y T-cells, Proc Natl Acad Sci USA 2006; 103(18) :7048-53.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.18 , pp. 7048-7053
    • Liu, H.1    Komai-Koma, M.2    Xu, D.3
  • 67
    • 2942590448 scopus 로고    scopus 로고
    • Synthetic lipopeptide adjuvants and Toll-like receptor 2 - Structure-activity relationships
    • DOI 10.1016/j.vaccine.2003.11.074, PII S0264410X04002610, Modern Vaccine Adjuvants and Delivery Systems
    • Spohn R, Buwitt-Beckmann U, Brock R et al. Synthetic lipopeptide adjuvants and Toll-like receptor 2-structure-activity relationships. Vaccine 2004; 22(19) :2494-9. (Pubitemid 38757349)
    • (2004) Vaccine , vol.22 , Issue.19 , pp. 2494-2499
    • Spohn, R.1    Buwitt-Beckmann, U.2    Brock, R.3    Jung, G.4    Ulmer, A.J.5    Wiesmuller, K.-H.6
  • 68
    • 9244224134 scopus 로고    scopus 로고
    • The Mycoplasma-derived macrophage-activating 2-kilodalton lipopeptide triggers global immune activation on nasal mucosa-associated lymphoid tissues
    • DOI 10.1128/IAI.72.12.6978-6986.2004
    • Rharbaoui F, WestendorfA, Link C et al. The Mycoplasma-derived macrophage-activaring 2-kilodalton lipopeptide triggers global immune activation on nasal mucosa-associated lymphoid tissues. Infect Immun 2004; 72(12) :6978-86. (Pubitemid 39552366)
    • (2004) Infection and Immunity , vol.72 , Issue.12 , pp. 6978-6986
    • Rharbaoui, F.1    Westendorf, A.2    Link, C.3    Felk, S.4    Buer, J.5    Gunzer, M.6    Guzman, C.A.7
  • 69
    • 33646357470 scopus 로고    scopus 로고
    • Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
    • DOI 10.1128/IAI.74.5.2809-2816.2006
    • Katz J, Zhang P, Martin M et al, Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS. Infect Immun 2006; 74(5):2809-16. (Pubitemid 43672990)
    • (2006) Infection and Immunity , vol.74 , Issue.5 , pp. 2809-2816
    • Katz, J.1    Zhang, P.2    Martin, M.3    Vogel, S.N.4    Michalek, S.M.5
  • 71
    • 15244342229 scopus 로고    scopus 로고
    • Effect of synthetic lipopeptides formulated in liposomes on the maturation of human dendritic cells
    • DOI 10.1016/j.molimm.2004.09.022
    • Espuelas S, Roth A, Thumann C et al. Effect of synthetic lipopeptides formulated in liposomes on the maturation of human dendritic cells. Mol Immunol 2005; 42(6) :721-9. (Pubitemid 40386714)
    • (2005) Molecular Immunology , vol.42 , Issue.6 , pp. 721-729
    • Espuelas, S.1    Roth, A.2    Thumann, C.3    Frisch, B.4    Schuber, F.5
  • 73
    • 0034995057 scopus 로고    scopus 로고
    • Development of immunoadjuvants for immunotherapy of cancer
    • DOI 10.1016/S1567-5769(01)00055-8, PII S1567576901000558
    • Azuma I, SeyaT. Development of immunoadjuvants for immunotherapy of cancer. Int Immunopharmacol 2001; 1(7):1249-59. (Pubitemid 32522979)
    • (2001) International Immunopharmacology , vol.1 , Issue.7 , pp. 1249-1259
    • Azuma, I.1    Seya, T.2
  • 74
    • 0016639224 scopus 로고
    • Immunologic properties of bacterial lipopolysaccharide (LPS): Correlation between the mitogenic , adjuvant and immunogenic activities
    • Skidmore BJ, Chiller JM, Morrison DC et al. Immunologic properties of bacterial lipopolysaccharide (LPS): correlation between the mitogenic , adjuvant and immunogenic activities. J Immunol 1975; 114(2 pt 2):770-5.
    • (1975) J Immunol , vol.114 , Issue.2 PART. 2 , pp. 770-775
    • Skidmore, B.J.1    Chiller, J.M.2    Morrison, D.C.3
  • 75
    • 0017359357 scopus 로고
    • Immunologic properties of bacterial lipopolysaccharide (LPS). IV. Cellular basis of the unresponsiveness of C3H/HeJ mouse spleen cells to LPS induced mitogenesis
    • Skidmore BJ, Chiller JM, Weigle WO et al. Immunologic properties of bacterial lipopo lysaccharide (LPS). IV. Cellular basis of the unresponsiveness of C3H/HeJ mouse spleen cells to LPS-induced mitogenesis. J Immunol 1977; 118(1) :274-81. (Pubitemid 8028539)
    • (1977) Journal of Immunology , vol.118 , Issue.1 , pp. 274-281
    • Skidmore, B.J.1    Chiller, J.M.2    Weigle, W.O.3
  • 76
    • 0016881599 scopus 로고
    • Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS
    • Skidmore BJ, Chiller JM, Weigle WO et al. Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS. J Exp Med 1976; 143(1) :143-50.
    • (1976) J Exp Med , vol.143 , Issue.1 , pp. 143-150
    • Skidmore, B.J.1    Chiller, J.M.2    Weigle, W.O.3
  • 77
    • 0016801894 scopus 로고
    • Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness ofC3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS
    • Skidmore BJ, Morrison DC, Chiller JM et al. Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness ofC3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS. J Exp Med 1975; 142(6):1488-508.
    • (1975) J Exp Med , vol.142 , Issue.6 , pp. 1488-1508
    • Skidmore, B.J.1    Morrison, D.C.2    Chiller, J.M.3
  • 79
    • 34250854079 scopus 로고    scopus 로고
    • The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
    • DOI 10.1126/science.1138963
    • Mara-Hare V. Cekic C, Martin M et al, The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist ofTLR4. Science 2007; 316(5831) :1628-32. (Pubitemid 46982038)
    • (2007) Science , vol.316 , Issue.5831 , pp. 1628-1632
    • Mata-Haro, V.1    Cekic, C.2    Martin, M.3    Chilton, P.M.4    Casella, C.R.5    Mitchell, T.C.6
  • 81
    • 0027375326 scopus 로고
    • Are immuno modulators capable to improve the activity of nucleoside antiretroviral agents?
    • (Paris)
    • Siner M, Pocidalo JJ. Are immuno modulators capable to improve the activity of nucleoside antiretroviral agents? J. Pathol Biol (Paris) 1993; 41(8 Pt 2):794-8.
    • (1993) J. Pathol Biol , vol.41 , Issue.8 PT. 2 , pp. 794-798
    • Siner, M.1    Pocidalo, J.J.2
  • 82
    • 0017108014 scopus 로고
    • A phase I-II trial of multiple-dose polyribolnosic-polyribocytidylic acid in parieonrs with leukemia or solid rumors
    • Robinson RA. DeVita VT. Levy HB et al. A phase I-II trial of multiple-dose polyribolnosic-polyribocytidylic acid in parieonrs with leukemia or solid rumors. J Natl Cancer Inst 1976; 57(3):599-602.
    • (1976) J Natl Cancer Inst , vol.57 , Issue.3 , pp. 599-602
    • Robinson, R.A.1    DeVita, V.T.2    Levy, H.B.3
  • 83
    • 0037472447 scopus 로고    scopus 로고
    • 21
    • Adams M. Navabi H, Jasani B et aL Dendritic cell (DC) based therapy for cervical cancer: use of DC pulsed with tumour lysate and matured with a novel synthetic clinically nontoxic double stranded RNA analogue poly [I]:poly [C(12)U] (Ampligen R). Vaccine 2003 30; 21(7-8):787-90.
    • (2003) Vaccine , vol.30 , Issue.7-8 , pp. 787-790
    • Adams, M.1    Navabi, H.2    Jasani, B.3
  • 84
    • 33845224163 scopus 로고    scopus 로고
    • Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity
    • DOI 10.1016/j.vaccine.2006.08.013, PII S0264410X0600956X
    • Huleatt JW, Jacobs AR, Tang J et al. Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity. Vaccine 2007; 25(4) :763-75. (Pubitemid 44856106)
    • (2007) Vaccine , vol.25 , Issue.4 , pp. 763-775
    • Huleatt, J.W.1    Jacobs, A.R.2    Tang, J.3    Desai, P.4    Kopp, E.B.5    Huang, Y.6    Song, L.7    Nakaar, V.8    Powell, T.J.9
  • 85
    • 31844436647 scopus 로고    scopus 로고
    • Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis
    • DOI 10.1128/IAI.74.2.1113-1120.2006
    • Honko AN, Sriranganathan N, Lees CJ et al Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis. Infect Immun 2006; 74(2) :1113-20. (Pubitemid 43185549)
    • (2006) Infection and Immunity , vol.74 , Issue.2 , pp. 1113-1120
    • Honko, A.N.1    Sriranganathan, N.2    Lees, C.J.3    Mizel, S.B.4
  • 86
    • 0037248211 scopus 로고    scopus 로고
    • Role of flagellin in the pathogenesis of shock and acute respiratory distress syndrome: Therapeutic opportunities
    • Szabo C. Role of flagellin in the pathogenesis of shock and acute respiratory distress syndrome: therapeutic opportunities. Crit Care Med 2003; 31(1 Suppl):S39-45 . (Pubitemid 36143476)
    • (2003) Critical Care Medicine , vol.31 , Issue.1 SUPPL.
    • Szabo, C.1
  • 87
    • 33745058640 scopus 로고    scopus 로고
    • Intracameral toxicity of bacterial components muramyl dipeptide and staurosporine: Ciliary cyst formation, epithelial cell apoptosis and necrosis
    • DOI 10.1080/15569520600695538, PII R82218727062
    • Langford MP. Chen D. Gosslee J et al. Intracameral toxicity of bacterial components muramyl dipeptide and staurosporine: ciliary cyst formation, epithelial cell apoptosis and necrosis. Cutan Ocul Toxicol 2006; 25(2) :85-101. (Pubitemid 43879618)
    • (2006) Cutaneous and Ocular Toxicology , vol.25 , Issue.2 , pp. 85-101
    • Langford, M.P.1    Chen, D.2    Gosslee, J.3    Misra, R.P.4    Redens, T.B.5    Texada, D.E.6
  • 88
    • 34548716509 scopus 로고    scopus 로고
    • Blocking of the TLR5 activation domain hampers protective potential of Flagellin DNA vaccine
    • Saha S. Takeshita F. Matsuda T et al. Blocking of the TLR5 Activation Domain Hampers Protective Potential of Flagellin DNA Vaccine.J Immunol 2007; 179(2) :1147-54.
    • (2007) J Immunol , vol.179 , Issue.2 , pp. 1147-1154
    • Saha, S.1    Takeshita, F.2    Matsuda, T.3
  • 89
    • 7444231521 scopus 로고    scopus 로고
    • Resiquimod: A new immune response modifier with potential as a vaccine adjuvant for Th1 immune responses
    • DOI 10.1016/j.antiviral.2004.07.002, PII S0166354204001615
    • Wu JJ. Huang DB. Tyring SK. Resiquimod: a new immune response modifier with potential as a vaccine adjuvant for Th1 immune responses. Antiviral Res 2004; 64(2):79-83. (Pubitemid 39446130)
    • (2004) Antiviral Research , vol.64 , Issue.2 , pp. 79-83
    • Wu, J.J.1    Huang, D.B.2    Tyring, S.K.3
  • 91
    • 0025930765 scopus 로고
    • Targeting and assembly of an oligomeric bacterial enterotoxoid in the endoplasmic reticulum of Saccharomyces cerevisiae
    • Schonberger O. Hirst TR. Pines O. Targeting and assembly of an oligomeric bacterial enrerotoxoid in the endoplasmic reticulum of Saccharomyces cerevisiae. Mol Microbiol 1991; 5(11) :2663-71. (Pubitemid 21895999)
    • (1991) Molecular Microbiology , vol.5 , Issue.11 , pp. 2663-2671
    • Schonberger, O.1    Hirst, T.R.2    Pines, O.3
  • 92
    • 0034741974 scopus 로고    scopus 로고
    • A review of the applications of imiquimoid: A novel immune response modifier
    • Syed TA. A review of the applications of imiquimod: a novel immune response modifier. Expert Opin Pharmacother 2001; 2(5):877-82. (Pubitemid 32750343)
    • (2001) Expert Opinion on Pharmacotherapy , vol.2 , Issue.5 , pp. 877-882
    • Syed, T.A.1
  • 93
    • 1842479742 scopus 로고    scopus 로고
    • Imiquimod and resiquimod in a mouse model: Adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery
    • DOI 10.1016/j.vaccine.2003.09.052, PII S0264410X04001045
    • Thomsen LL. Topley P. Daly MG et al. Imiquimod and resiquimod in a mouse model: adjuvants for DNA vaccination by panicle-mediated immunotherapeutic delivery. Vaccine 2004; 22(13-14):1799-809. (Pubitemid 38447228)
    • (2004) Vaccine , vol.22 , Issue.13-14 , pp. 1799-1809
    • Thomsen, L.L.1    Topley, P.2    Daly, M.G.3    Brett, S.J.4    Tite, J.P.5
  • 94
    • 33745651083 scopus 로고    scopus 로고
    • A review of CpGs and their relevance to aquaculture
    • DOI 10.1016/j.vetimm.2006.03.015, PII S0165242706001024
    • Carrington AC. Secombes CJ, A review of CpGs and their relevance to aquaculture. Vet Immunol Immunopathol 2006; 112(3-4) :87-101. (Pubitemid 43975152)
    • (2006) Veterinary Immunology and Immunopathology , vol.112 , Issue.3-4 , pp. 87-101
    • Carrington, A.C.1    Secombes, C.J.2
  • 96
    • 24144492673 scopus 로고    scopus 로고
    • Safety of CpG oligodeoxynucleotides in veterinary species
    • Ioannou XP. Griebel P, Mena A et al. Safety of CpG oligodeoxynucleotides in veterinary species. Antisense Nucleic Acid Drug Dev 2003; 13(3):157-67.
    • (2003) Antisense Nucleic Acid Drug Dev , vol.13 , Issue.3 , pp. 157-167
    • Ioannou, X.P.1    Griebel, P.2    Mena, A.3
  • 97
    • 0034670157 scopus 로고    scopus 로고
    • The role of CpG motifs in immunostimulation and gene therapy
    • Scheule RK. The role of CpG motifs in immunostimulation and gene therapy. Adv Drug Deliv Rev 2000 ; 44(2-3) :119-34.
    • (2000) Adv Drug Deliv Rev , vol.44 , Issue.2-3 , pp. 119-134
    • Scheule, R.K.1
  • 98
    • 0034046182 scopus 로고    scopus 로고
    • DNA vaccines: Immunology, application, and optimization
    • DOI 10.1146/annurev.immunol.18.1.927
    • Gurunathan S. Klinman DM. Seder RA. DNA Vaccines: Immunology. Application and Optimization. Annu Rev Immunol 2000; 18(1):927-74. (Pubitemid 30365401)
    • (2000) Annual Review of Immunology , vol.18 , pp. 927-974
    • Gurunathan, S.1    Klinman, D.M.2    Seder, R.A.3
  • 99
    • 0036917474 scopus 로고    scopus 로고
    • CpG DNA in the prevention and treatment of infections
    • DOI 10.2165/00063030-200216060-00003
    • Dalpke A. Zimmermann S. Heeg K. CpG DNA in the prevention and treatment of infections. BioDrugs 2002; 16(6):419-31. (Pubitemid 36020852)
    • (2002) BioDrugs , vol.16 , Issue.6 , pp. 419-431
    • Dalpke, A.1    Zimmermann, S.2    Heeg, K.3
  • 100
    • 17644386241 scopus 로고    scopus 로고
    • Differential binding of Escherichia coli enterotoxins LT-IIa and LT-IIb and of cholera toxin elicits differences in apoptosis, proliferation, and activation of lymphoid cells
    • DOI 10.1128/IAI.73.5.2718-2727.2005
    • Arce S. Nawar HF. Russell MW et al. Differential binding of Escherichia coli enterotoxins LT-IIa and LT-IIb and of cholera toxin elicits differences in apoptosis, proliferation and activation of lymphoid cells. Infect Immun 2005; 73(5):2718-27. (Pubitemid 40570337)
    • (2005) Infection and Immunity , vol.73 , Issue.5 , pp. 2718-2727
    • Arce, S.1    Nawar, H.F.2    Russell, M.W.3    Connell, T.D.4
  • 101
    • 0023916532 scopus 로고
    • Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa and LT-IIb
    • Fukuta S. Magnani JL. Twiddy EM et al. Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa and LT-IIb. Infect Immun 1988; 56(7) :1748-53.
    • (1988) Infect Immun , vol.56 , Issue.7 , pp. 1748-1753
    • Fukuta, S.1    Magnani, J.L.2    Twiddy, E.M.3
  • 102
    • 35348850079 scopus 로고    scopus 로고
    • Antigenicity, safety and efficacy of a recombinant coccidioidomycosis vaccine in cynomolgus maques (Macaca fascicularis)
    • Johnson SM. Lerche NW; Pappagianis D et al. Antigenicity, safety and efficacy of a recombinant coccidioidomycosis vaccine in cynomolgus maques (Macaca fascicularis). Ann NY Acad Sci 2007.
    • (2007) Ann NY Acad Sci
    • Johnson, S.M.1    Lerche, N.W.2    Pappagianis, D.3
  • 103
    • 34249866843 scopus 로고    scopus 로고
    • Induction of cell signaling events by the cholera toxin B subunit in antigen-presenting cells
    • DOI 10.1128/IAI.00581-06
    • Schnitzler AC. Burke JM. Wetzler LM. Induction of cell signaling events by the cholera toxin B subunit in antigen-presenting cells. Infect Immun 2007; 75(6) :3150-9. (Pubitemid 46870201)
    • (2007) Infection and Immunity , vol.75 , Issue.6 , pp. 3150-3159
    • Schnitzler, A.C.1    Burke, J.M.2    Wetzler, L.M.3
  • 105
    • 0033753162 scopus 로고    scopus 로고
    • Immune modulation by the cholera-like enterotoxin B-subunits: From adjuvant to immunotherapeutic
    • Williams NA. Immune modulation by the cholera-like enterotoxin B-subunits: from adjuvant to immunotherapeutic. Int J Med Microbiol 2000; 290(4-5):447-53.
    • (2000) Int J Med Microbiol , vol.290 , Issue.4-5 , pp. 447-453
    • Williams, N.A.1
  • 107
    • 3042633740 scopus 로고    scopus 로고
    • Modulation of the immune response by the cholera-like enterotoxins
    • DOI 10.2174/1568026043451230
    • Plant A. Williams NA. Modulation of the immune response by the cholera-like enterotoxins. Curr Top Med Chem 2004; 4(5):509-19. (Pubitemid 38832734)
    • (2004) Current Topics in Medicinal Chemistry , vol.4 , Issue.5 , pp. 509-519
    • Plant, A.1    Williams, N.A.2
  • 109
    • 19944431804 scopus 로고    scopus 로고
    • Activated NKT cells inhibit auto immune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes
    • Chen YG. Choisy-Rossi CM. Holl TM et al. Activated NKT cells inhibit auto immune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes. J Immunol 2005; 174(3) :1196-204.
    • (2005) J Immunol , vol.174 , Issue.3 , pp. 1196-1204
    • Chen, Y.G.1    Choisy-Rossi, C.M.2    Holl, T.M.3
  • 110
    • 3042767903 scopus 로고    scopus 로고
    • Natural killer T cells as targets for immunotherapy of autoimmune diseases
    • DOI 10.1111/j.0818-9641.2004.01252.x
    • Van Kaer L. Natural killer T-cells as targets for immunotherapy of autoimmune diseases. Immunol Cell Biol 2004; 82(3):315 -22. (Pubitemid 38870026)
    • (2004) Immunology and Cell Biology , vol.82 , Issue.3 , pp. 315-322
    • Van Kaer, L.1
  • 115
    • 0033549676 scopus 로고    scopus 로고
    • Synthesis of NBD-alpha-galactosylceramide and its immunologic properties
    • Sakai T. Ehara H, Koezuka Y. Synthesis of NBD-alpha-galactosylceramide and its immunologic properties. Org Lett 1999; 1(3):359-61.
    • (1999) Org Lett , vol.1 , Issue.3 , pp. 359-61
    • Sakai, T.1    Ehara, H.2    Koezuka, Y.3
  • 116
    • 33644848056 scopus 로고    scopus 로고
    • Galectin-9 induces maturation of human monocyte-derived dendritic cells
    • Yamauchi A, Dai SY, Nakagawa R et al. [Galectin-9 induces maturation of human monocyte-derived dendritic cellsJ. Nihon Rinsho Meneki Gakkai Kaishi 2005; 28(6):381-8.
    • (2005) Nihon Rinsho Meneki Gakkai Kaishi , vol.28 , Issue.6 , pp. 381-388
    • Yamauchi, A.1    Dai, S.Y.2    Nakagawa, R.3
  • 117
    • 34250219958 scopus 로고    scopus 로고
    • A single intranasal immunization with inactivated influenza virus and alpha-galactosylceramide induces long-term protective immunity without redirecting antigen to the central nervous system
    • Youn HJ, Ko SY,Lee KA et al,A single intranasal immunization with inactivated influenza virus and alpha-galactosylceramide induces long-term protective immunity without redirecting antigen to the central nervous system. Vaccine 2007; 25(28) :5189-98.
    • (2007) Vaccine , vol.25 , Issue.28 , pp. 5189-5198
    • Youn, H.J.1    Ko, S.Y.2    Lee, K.A.3
  • 119
    • 34848874475 scopus 로고    scopus 로고
    • A Pegylated Derivative of {alpha}-Galactosylceramide Exhibits Improved Biological Properties
    • Ebensen T, Link C, Riese P et al. A Pegylated Derivative of {alpha}-Galactosylceramide Exhibits Improved Biological Properties. J Immunol 2007; 179(4) :2065-73.
    • (2007) J Immunol , vol.179 , Issue.4 , pp. 2065-2073
    • Ebensen, T.1    Link, C.2    Riese, P.3
  • 120
    • 0035987399 scopus 로고    scopus 로고
    • IL-12/IL-2 combination cytokine therapy for solid tumours: Translation from bench to bedside
    • DOI 10.1517/14712598.2.5.513
    • Wigginton JM, Wiltrout RH. IL-12/IL-2 combination cytokine therapy for solid tumours: translation from bench to bedside. Expert Opin Biol Ther 2002; 2(5) :513-24. (Pubitemid 34716734)
    • (2002) Expert Opinion on Biological Therapy , vol.2 , Issue.5 , pp. 513-524
    • Wigginton, J.M.1    Wiltrout, R.H.2
  • 121
    • 33745499027 scopus 로고    scopus 로고
    • Regulation of innate and adaptive immune responses by the related cytokines IL-12, IL-23, and IL-27
    • DOI 10.1007/s00005-006-0002-6
    • Beadling C, Slifka MK. Regulation of innate and adaptive immune responses by the related cytokines IL-12, IL-23 and IL-27. Arch Immunol Ther Exp (Warsz) 2006; 54(1) :15-24. (Pubitemid 44124218)
    • (2006) Archivum Immunologiae et Therapiae Experimentalis , vol.54 , Issue.1 , pp. 15-24
    • Beadling, C.1    Slifka, M.K.2
  • 122
    • 0034074164 scopus 로고    scopus 로고
    • Interleukin -2 in the treatment of renal cancer
    • Margolin KA. Interleukin -2 in the treatment of renal cancer. Semin Oncol 2000; 27(2):194-203.
    • (2000) Semin Oncol , vol.27 , Issue.2 , pp. 194-203
    • Margolin, K.A.1
  • 124
    • 33646078924 scopus 로고    scopus 로고
    • Therapeutic potential of cytokine and chemokine antagonists in cancer therapy
    • Yan L, Anderson GM, DeWitte M et al. Therapeutic potential of cytokine and chemokine antagonists in cancer therapy. Eur J Cancer 2006; 42(6):793-802.
    • (2006) Eur J Cancer , vol.42 , Issue.6 , pp. 793-802
    • Yan, L.1    Anderson, G.M.2    DeWitte, M.3
  • 125
    • 32844468663 scopus 로고    scopus 로고
    • Chernokines in tumor immuno therapy
    • Flanagan K, Kaufman HL. Chernokines in tumor immuno therapy. Front Biosci 2006; 11:1024-30.
    • (2006) Front Biosci , vol.11 , pp. 1024-1030
    • Flanagan, K.1    Kaufman, H.L.2
  • 126
    • 33751249635 scopus 로고    scopus 로고
    • The chemokine network: A target in cancer biology?
    • DOI 10.1016/j.addr.2006.03.012, PII S0169409X06001414
    • Slettenaar VI. Wilson JL. The chemokine network: a target in cancer biology? Adv Drug Deliv Rev 2006; 58(8) :962-74. (Pubitemid 44780906)
    • (2006) Advanced Drug Delivery Reviews , vol.58 , Issue.8 , pp. 962-974
    • Slettenaar, V.I.F.1    Wilson, J.L.2
  • 127
    • 34247196171 scopus 로고    scopus 로고
    • Clinical utilization of chemokines to combat cancer: The double-edged sword
    • DOI 10.1586/14760584.6.2.267
    • Dell'Agnola C, Biragyn A. Clinical utilization of chemokines to combat cancer: the double-edged sword. Expert Rev Vaccines 2007; 6(2) :267-83. (Pubitemid 46607460)
    • (2007) Expert Review of Vaccines , vol.6 , Issue.2 , pp. 267-283
    • Dell'Agnola, C.1    Biragyn, A.2
  • 130
    • 0037992889 scopus 로고    scopus 로고
    • Cytokines as clinical adjuvants: How far are we?
    • DOI 10.1586/14760584.2.2.317
    • Villinger F. Cyrokines as clinical adjuvants: how far are we? Expert Rev Vaccines 2003; 2(2) :317-26. (Pubitemid 36564801)
    • (2003) Expert Review of Vaccines , vol.2 , Issue.2 , pp. 317-326
    • Villinger, F.1
  • 131
    • 0016200846 scopus 로고
    • Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives
    • Ellouz F, Adam A, Ciorbaru R et al. Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives. Biochem Biophys Res Commun 1974; 59(4):1317-25.
    • (1974) Biochem Biophys Res Commun , vol.59 , Issue.4 , pp. 1317-1325
    • Ellouz, F.1    Adam, A.2    Ciorbaru, R.3
  • 134
    • 77951073629 scopus 로고    scopus 로고
    • NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis
    • Ferwerda G, Girardin SE, Kullberg BJ et al, NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. PLoS Pathog 2005 ; 1(3):279-85.
    • (2005) PLoS Pathog , vol.1 , Issue.3 , pp. 279-285
    • Ferwerda, G.1    Girardin, S.E.2    Kullberg, B.J.3
  • 135
    • 0032586965 scopus 로고    scopus 로고
    • The interaction of immunomodulator muramyl dipeptide with peripheral 5-HT receptors: Overview of the current state
    • DOI 10.1016/S0192-0561(98)00079-4, PII S0192056198000794
    • Sevcik J, Masek K. The interaction of immunomodulatory muramyl dipeptide with peripheral 5-HT receptors: overview of the current state. Int J Immunopharmacol 1999; 21(3):227-32. (Pubitemid 29142444)
    • (1999) International Journal of Immunopharmacology , vol.21 , Issue.3 , pp. 227-232
    • Sevcik, J.1    Masek, K.2
  • 136
    • 0042873015 scopus 로고    scopus 로고
    • Synthetic vaccines: The role of adjuvants in immune targeting
    • Jiang ZH, Koganry RR. Synthetic vaccines: the role of adjuvants in immune targeting. Curr Med Chem 2003; 10(15) :1423-39.
    • (2003) Curr Med Chem , vol.10 , Issue.15 , pp. 1423-1439
    • Jiang, Z.H.1    Koganry, R.R.2
  • 137
    • 0026578350 scopus 로고
    • Enhancement of the effectiveness of antimicrobia l therapy by muramyl pept ide imrnunomodularors
    • O'Reilly T, Zak O. Enhancement of the effectiveness of antimicrobia l therapy by muramyl pept ide imrnunomodularors. Clin Infect Dis 1992; 14(5):1100-9.
    • (1992) Clin Infect Dis , vol.14 , Issue.5 , pp. 1100-1109
    • O'Reilly, T.1    Zak, O.2
  • 138
    • 0031608311 scopus 로고    scopus 로고
    • Muramyl dipeptide derivativesin experimental and clinical use
    • Kaliuzhin OV. [Muramyl dipeptide derivativesin experimental and clinical use J. Zh Mikrobiol Epidemiol Immunobiol 1998:104-8.
    • (1998) J. Zh Mikrobiol Epidemiol Immunobiol , pp. 104-108
    • Kaliuzhin, O.V.1
  • 139
    • 0028292214 scopus 로고
    • Liposomes, muramyl dipeptide derivatives, and nontoxic lipid a derivatives as adjuvants for human malaria vaccines
    • Hui GS. Liposomes, muramyl dipeptide derivatives and nontoxic lipid A derivatives as adjuvants for human malaria vaccines. Am J Trop Med Hyg 1994; 50(4 Suppl):41-51. (Pubitemid 24158403)
    • (1994) American Journal of Tropical Medicine and Hygiene , vol.50 , Issue.4 SUPPL. , pp. 41-51
    • Hui, G.S.N.1
  • 140
    • 34250372922 scopus 로고    scopus 로고
    • Immune modulator adamanrylamide dipeptide stimulates efficient major histocompatibility complex class l-restricted responses in mice
    • Becker PD, Norder M. Guzman CA et al. Immune modulator adamanrylamide dipeptide stimulates efficient major histocompatibility complex class l-restricted responses in mice. Clin Vaccine Immunol 2007; 14(5):538-43.
    • (2007) Clin Vaccine Immunol , vol.14 , Issue.5 , pp. 538-543
    • Becker, P.D.1    Norder, M.2    Guzman, C.A.3
  • 141
    • 34147127485 scopus 로고    scopus 로고
    • Intranasal vaccination with recombinant outer membrane protein CD and adamantylamide dipeptide as the mucosal adjuvant enhances pulmonary clearance of Moraxella catarrhalis in an experimental murine model
    • DOI 10.1128/IAI.01081-06
    • Becker PD, Bertot GM, SoussD et al. Intranasal vaccination with recombinant outer membrane protein CD and adarnanrylamide dipeptide as the mucosal adjuvant enhances pulmonary clearance of Moraxella catarrhal is in an experimental murine model. Infect Immun 2007 ; 75(4) :1778-84. (Pubitemid 46559445)
    • (2007) Infection and Immunity , vol.75 , Issue.4 , pp. 1778-1784
    • Becker, P.D.1    Bertot, G.M.2    Souss, D.3    Ebensen, T.4    Guzman, C.A.5    Grinstein, S.6
  • 142
    • 1842607669 scopus 로고    scopus 로고
    • Intranasal vaccination with recombinant P6 protein and adamantylamide dipeptide as mucosal adjuvant confers efficient protection against otitis media and lung infection by nontypeable Haemophilus influenzae
    • DOI 10.1086/382508
    • Bertot GM, Becker PD, Guzman CA et al. Intranasal vaccination with recombinant P6 protein and adamantylamide dipeptide as mucosal adjuvant confers efficient protection against otitis media and lung infection by nontypeable Haemophilus influenzae. J Infect Dis 2004; 189(7):1304-12. (Pubitemid 38457257)
    • (2004) Journal of Infectious Diseases , vol.189 , Issue.7 , pp. 1304-1312
    • Bertot, G.M.1    Becker, P.D.2    Guzman, C.A.3    Grinstein, S.4
  • 143
    • 0035860625 scopus 로고    scopus 로고
    • Adamantylamide dipeptide as effective immunoadjuvant in rabbits and mice
    • DOI 10.1016/S0264-410X(01)00259-6, PII S0264410X01002596
    • Becker PD, Corral RS. Guzman CA et al. Adamanrylamide dipeptide as effective immunoadjuvantin rabbits and mice. Vaccine 2001; 19(32) :4603-9. (Pubitemid 32800741)
    • (2001) Vaccine , vol.19 , Issue.32 , pp. 4603-4609
    • Becker, P.D.1    Corral, R.S.2    Guzman, C.A.3    Grinstein, S.4
  • 144
    • 0037083150 scopus 로고    scopus 로고
    • CD154 and type-1 cytokine response: From hyper IgM syndrome to human immunodeficiency virus infection
    • DOI 10.1086/338003
    • Subauste CS. CD154 and type-I eytokine response: from hyper IgM syndrome to human immunodeficiency virus Infecdon.J Infect Dis 2002; 185 Suppl. I:S83-9. (Pubitemid 34142833)
    • (2002) Journal of Infectious Diseases , vol.185 , Issue.SUPPL. 1
    • Subauste, C.S.1
  • 145
    • 33645215961 scopus 로고    scopus 로고
    • Costimulatory agonisrs as immunological adjuvants
    • Barr TA. Carlring J , Heath AW. Costimulatory agonisrs as immunological adjuvants. Vaccine 2006; 24( 17):3399-407.
    • (2006) Vaccine , vol.24 , Issue.17 , pp. 3399-3407
    • Barr, T.A.1    Carlring, J.2    Heath, A.W.3
  • 146
    • 14244259823 scopus 로고    scopus 로고
    • Adjuvanticity of anti-cD4Oin vaccine developrnenr
    • Cairing J. Barr T, Heath AW.Adjuvanticity of anti-cD4Oin vaccine developrnenr, Curr Opin Mol Ther 2005; 7(1):73-7.
    • (2005) Curr Opin Mol Ther , vol.7 , Issue.1 , pp. 73-77
    • Cairing, J.1    Barr, T.2    Heath, A.W.3
  • 147
    • 0037404151 scopus 로고    scopus 로고
    • Cytokine, chemokine, and costimulatory molecule modulation to enhance efficacy of HIV vaccines
    • DOI 10.2174/1566524033479843
    • Ahlers JD, Bdyakov IM, Berzofsky JA. Cytokine, chemokine and costimulatory molecule modulation to enhance efficacyof HIV vaccines. Curr Mol Med 2003; 3(3):285-301. (Pubitemid 36443226)
    • (2003) Current Molecular Medicine , vol.3 , Issue.3 , pp. 285-301
    • Ahlers, J.D.1    Belyakov, I.M.2    Berzofsky, J.A.3
  • 148
    • 2942592429 scopus 로고    scopus 로고
    • Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40
    • Sugamura K, Ishii N. Weinberg AD. Therapeutic targeting of the effector T-cdl costimulatory molecule OX4O. Nat Rev Immunol 2004; 4(6) :420-31. (Pubitemid 38745554)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.6 , pp. 420-431
    • Sugamura, K.1    Ishii, N.2    Weinberg, A.D.3
  • 149
    • 0028223557 scopus 로고
    • T-helper- and accessory-cell-independent cytotoxic responses to human tumor cells transfected with a B7 retroviral vector
    • DOI 10.1002/ijc.2910570524
    • Dohring C. Angman L, Spagnoli G et al. T-hdper- and accessory-cell- independent cytotoxic responses to human tumor cells eransfecred with a B7 rerroviral vector, Int J Cancer 1994; 57(5):754-9. (Pubitemid 24201371)
    • (1994) International Journal of Cancer , vol.57 , Issue.5 , pp. 754-759
    • Dohring, C.1    Angman, L.2    Spagnoli, G.3    Lanzavecchia, A.4
  • 150
    • 0027946018 scopus 로고
    • B7-1/CD80-transduced tumor cells elicit better systemic immunity than wild-type tumor cells admixed with Corynebacterium parvum
    • Chen L. McGowan P, Ashe S et al. B7-1/CD80-rransduced tumor cells dicit better systemic immunity than wild-type tumor cells admixed with Corynebacterium parvum. Cancer Res 1994; 54(20):5420-3. (Pubitemid 24336035)
    • (1994) Cancer Research , vol.54 , Issue.20 , pp. 5420-5423
    • Chen, L.1    McGowan, P.2    Ashe, S.3    Johnston, J.V.4    Hellstrom, I.5    Hellstrom, K.E.6
  • 151
    • 0027982995 scopus 로고
    • Tumor immunogenicity determines the effeer ofB7 costimulation on Tvcell-medlaced tumor immunity
    • Chen L. McGowan P, Ashe S et al. Tumor immunogenicity determines the effeer ofB7 costimulation on Tvcell-medlaced tumor immunity. J Exp Med 1994; 179(2):523-32.
    • (1994) J Exp Med , vol.179 , Issue.2 , pp. 523-532
    • Chen, L.1    McGowan, P.2    Ashe, S.3
  • 152
    • 0033605240 scopus 로고    scopus 로고
    • The use of combination vaccinia vaccines and dual-gene vaccinia vaccines to enhance antigen-specific T-cell immunity via T-cell costimulation
    • DOI 10.1016/S0264-410X(98)00275-8, PII S0264410X98002758
    • Kalus RM. Kantor JA. Gritz L et al. The use of combination vaccinia vaccines and dual-gene vaccinia vaccines to enhance antigen-specific T-cell immunity via T-cell costimulation. Vaccine 1999; 17(7-8):893-903. (Pubitemid 29074744)
    • (1999) Vaccine , vol.17 , Issue.7-8 , pp. 893-903
    • Kalus, R.M.1    Kantor, J.A.2    Gritz, L.3    Yafal, A.G.4    Mazzara, G.P.5    Schlom, J.6    Hodge, J.W.7
  • 153
    • 33645894689 scopus 로고    scopus 로고
    • Cyclic di-GMP as a second messenger
    • Romling U, Amikam D. Cyclic di-GMP as a second messenger. Curr Opin Microbiol 2006; 9(2):218-28.
    • (2006) Curr Opin Microbiol , vol.9 , Issue.2 , pp. 218-228
    • Romling, U.1    Amikam, D.2
  • 154
    • 22644438480 scopus 로고    scopus 로고
    • C-di-GMP: The dawning of a novel bacterial signalling system
    • DOI 10.1111/j.1365-2958.2005.04697.x
    • Romling U. Gomdsky M. Galperin MY. C-di-GMP: the dawning of a novd bacterial signalling system. Mol Microbiol 2005; 57(3):629-39. (Pubitemid 41025947)
    • (2005) Molecular Microbiology , vol.57 , Issue.3 , pp. 629-639
    • Romling, U.1    Gomelsky, M.2    Galperin, M.Y.3
  • 156
    • 33846055330 scopus 로고    scopus 로고
    • The bacterial second messenger cyclic diGMP exhibits potent adjuvant properties
    • DOI 10.1016/j.vaccine.2006.10.033, PII S0264410X0601156X
    • Ebensen T, Schulze K. Riese P et al. The bacterial second messenger cyclic diGMP exhibits potent adjuvant properties. Vaccine 2007; 25(8):1464-9. (Pubitemid 46074291)
    • (2007) Vaccine , vol.25 , Issue.8 , pp. 1464-1469
    • Ebensen, T.1    Schulze, K.2    Riese, P.3    Link, C.4    Morr, M.5    Guzman, C.A.6
  • 157
    • 34948813217 scopus 로고    scopus 로고
    • The bacterial second messenger cdiGMP exhibits promising activity as mucosal adjuvant
    • Ebensen T, Schulze K. Riese P et al. The bacterial second messenger cdiGMP exhibits promising activity as mucosal adjuvant. Clin Vaccine Immunol 2007; 14(8):952-8.
    • (2007) Clin Vaccine Immunol , vol.14 , Issue.8 , pp. 952-958
    • Ebensen, T.1    Schulze, K.2    Riese, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.