메뉴 건너뛰기




Volumn 11, Issue 8, 2010, Pages 608-617

Heat shock protein 90 protects rat mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis via the PI3K/Akt and ERK1/2 pathways

Author keywords

Apoptosis; Extracellular signal regulate kinase (ERK); Heat shock protein; Hypoxia; Phosphoinositide 3 kinase protein kinase B (PI3K Akt); Stem cell

Indexed keywords

CASPASE 3; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEAT SHOCK PROTEIN 90; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; RECOMBINANT HSP90; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

EID: 77955486750     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.B1001007     Document Type: Article
Times cited : (40)

References (38)
  • 1
    • 34249820803 scopus 로고    scopus 로고
    • Hsp90: A novel target for the disruption of multiple signaling cascades
    • DOI 10.2174/156800907780809778
    • S.C. Bishop J.A. Burlison B.S. Blagg 2007 Hsp90: a novel target for the disruption of multiple signaling cascades Current Cancer Drug Targets 7 4 369 388 10.2174/156800907780809778 1:CAS:528:DC%2BD2sXmsV2msrk%3D 17979631 (Pubitemid 46849241)
    • (2007) Current Cancer Drug Targets , vol.7 , Issue.4 , pp. 369-388
    • Bishop, S.C.1    Burlison, J.A.2    Blagg, B.S.J.3
  • 2
    • 38649094249 scopus 로고    scopus 로고
    • Heat shock proteins: Stress proteins with Janus-like properties in cancer
    • DOI 10.1080/02656730701858305, PII 789891263, cellular and vascular effects of hyperthermia, guest editors: Valeria Milani and Michael Horsman
    • S.K. Calderwood D.R. Ciocca 2008 Heat shock proteins: stress proteins with Janus-like properties in cancer International Journal of Hyperthermia 24 1 31 39 10.1080/02656730701858305 1:CAS:528:DC%2BD1cXovFKnsw%3D%3D 18214767 (Pubitemid 351167617)
    • (2008) International Journal of Hyperthermia , vol.24 , Issue.1 , pp. 31-39
    • Calderwood, S.K.1    Ciocca, D.R.2
  • 4
    • 49249127331 scopus 로고    scopus 로고
    • Paracrine effects of cell transplantation: Strategies to augment the efficacy of cell therapies
    • 10.1053/j.semtcvs.2008.04.003 18707640
    • A.S. Cheng T.M. Yau 2008 Paracrine effects of cell transplantation: strategies to augment the efficacy of cell therapies Seminars in Thoracic and Cardiovascular Surgery 20 2 94 101 10.1053/j.semtcvs.2008.04.003 18707640
    • (2008) Seminars in Thoracic and Cardiovascular Surgery , vol.20 , Issue.2 , pp. 94-101
    • Cheng, A.S.1    Yau, T.M.2
  • 5
    • 22144475112 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: Short- and long-term effects
    • DOI 10.1161/CIRCULATIONAHA.104.527937
    • W. Dai S.L. Hale B.J. Martin J.Q. Kuang J.S. Dow L.E. Wold R.A. Kloner 2005 Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects Circulation 112 2 214 223 10.1161/CIRCULATIONAHA.104.527937 15998673 (Pubitemid 40982304)
    • (2005) Circulation , vol.112 , Issue.2 , pp. 214-223
    • Dai, W.1    Hale, S.L.2    Martin, B.J.3    Kuang, J.-Q.4    Dow, J.S.5    Wold, L.E.6    Kloner, R.A.7
  • 6
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival - Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
    • DOI 10.1016/0022-1759(86)90368-6
    • F. Denizot R. Lang 1986 Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability Journal of Immunological Methods 89 2 271 277 10.1016/0022-1759(86)90368-6 1:STN:280:DyaL287psl2jsA%3D%3D 3486233 (Pubitemid 16080782)
    • (1986) Journal of Immunological Methods , vol.89 , Issue.2 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 7
    • 36549074157 scopus 로고    scopus 로고
    • Hsp90-mediated inhibition of FKBP38 regulates apoptosis in neuroblastoma cells
    • DOI 10.1016/j.febslet.2007.11.037, PII S0014579307011817
    • F. Erdmann F. Jarczowski M. Weiwad G. Fischer F. Edlich 2007 Hsp90-mediated inhibition of FKBP38 regulates apoptosis in neuroblastoma cells FEBS Letters 581 29 5709 5714 10.1016/j.febslet.2007.11.037 1:CAS:528: DC%2BD2sXhtlykt7jK 18036348 (Pubitemid 350182414)
    • (2007) FEBS Letters , vol.581 , Issue.29 , pp. 5709-5714
    • Erdmann, F.1    Jarczowski, F.2    Weiwad, M.3    Fischer, G.4    Edlich, F.5
  • 8
    • 0036136667 scopus 로고    scopus 로고
    • The inflammatory response in myocardial infarction
    • DOI 10.1016/S0008-6363(01)00434-5, PII S0008636301004345
    • N.G. Frangogiannis C.W. Smith M.L. Entman 2002 The inflammatory response in myocardial infarction Cardiovascular Research 53 1 31 47 10.1016/S0008- 6363(01)00434-5 1:CAS:528:DC%2BD3MXptVahsb0%3D 11744011 (Pubitemid 34020764)
    • (2002) Cardiovascular Research , vol.53 , Issue.1 , pp. 31-47
    • Frangogiannis, N.G.1    Smith, C.W.2    Entman, M.L.3
  • 9
    • 34948844553 scopus 로고    scopus 로고
    • Heregulin protects mesenchymal stem cells from serum deprivation and hypoxia-induced apoptosis
    • DOI 10.1007/s11010-007-9541-3
    • C. Gui J.A. Wang A.N. He T.L. Chen R.H. Luo J. Jiang X.Y. Hu X.J. Xie 2007 Heregulin protects mesenchymal stem cells from serum deprivation and hypoxia-induced apoptosis Molecular and Cellular Biochemistry 305 1-2 171 178 10.1007/s11010-007-9541-3 1:CAS:528:DC%2BD2sXhtFSksLnM 17619951 (Pubitemid 47517179)
    • (2007) Molecular and Cellular Biochemistry , vol.305 , Issue.1-2 , pp. 171-178
    • Gui, C.1    Wang, J.A.2    He, A.N.3    Chen, T.L.4    Luo, R.H.5    Jiang, J.6    Hu, X.Y.7    Xie, X.J.8
  • 10
    • 39549105786 scopus 로고    scopus 로고
    • Pre-Treatment of Mesenchymal Stem Cells With a Combination of Growth Factors Enhances Gap Junction Formation, Cytoprotective Effect on Cardiomyocytes, and Therapeutic Efficacy for Myocardial Infarction
    • DOI 10.1016/j.jacc.2007.11.040, PII S0735109707038089
    • J.Y. Hahn H.J. Cho H.J. Kang T.S. Kim M.H. Kim J.H. Chung J.W. Bae B.H. Oh Y.B. Park H.S. Kim 2008 Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction Journal of the American College of Cardiology 51 9 933 943 10.1016/j.jacc.2007. 11.040 1:CAS:528:DC%2BD1cXislWlu7w%3D 18308163 (Pubitemid 351282455)
    • (2008) Journal of the American College of Cardiology , vol.51 , Issue.9 , pp. 933-943
    • Hahn, J.-Y.1    Cho, H.-J.2    Kang, H.-J.3    Kim, T.-S.4    Kim, M.-H.5    Chung, J.-H.6    Bae, J.-W.7    Oh, B.-H.8    Park, Y.-B.9    Kim, H.-S.10
  • 11
    • 52049119289 scopus 로고    scopus 로고
    • Mesenchymal stem cell administration at coronary artery reperfusion in the rat by two delivery routes: A quantitative assessment
    • 10.1016/j.lfs.2008.07.020 1:CAS:528:DC%2BD1cXhtFekt7nO 18755200
    • S.L. Hale W. Dai J.S. Dow R.A. Kloner 2008 Mesenchymal stem cell administration at coronary artery reperfusion in the rat by two delivery routes: a quantitative assessment Life Sciences 83 13-14 511 515 10.1016/j.lfs.2008.07. 020 1:CAS:528:DC%2BD1cXhtFekt7nO 18755200
    • (2008) Life Sciences , vol.83 , Issue.1314 , pp. 511-515
    • Hale, S.L.1    Dai, W.2    Dow, J.S.3    Kloner, R.A.4
  • 12
    • 24644459322 scopus 로고    scopus 로고
    • Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: Implications for current clinical trials
    • D. Hou E.A. Youssef T.J. Brinton P. Zhang P. Rogers E.T. Price A.C. Yeung B.H. Johnstone P.G. Yock K.L. March 2005 Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials Circulation 112 9Suppl.I 150 156
    • (2005) Circulation , vol.112 , Issue.9 SUPPL. I , pp. 150-156
    • Hou, D.1    Youssef, E.A.2    Brinton, T.J.3    Zhang, P.4    Rogers, P.5    Price, E.T.6    Yeung, A.C.7    Johnstone, B.H.8    Yock, P.G.9    March, K.L.10
  • 13
    • 57749098707 scopus 로고    scopus 로고
    • In vitro effects of low-level laser irradiation for bone marrow mesenchymal stem cells: Proliferation, growth factors secretion and myogenic differentiation
    • 10.1002/lsm.20709 19065562
    • J.F. Hou H. Zhang X. Yuan J. Li Y.J. Wei S.S. Hu 2008 In vitro effects of low-level laser irradiation for bone marrow mesenchymal stem cells: proliferation, growth factors secretion and myogenic differentiation Lasers in Surgery and Medicine 40 10 726 733 10.1002/lsm.20709 19065562
    • (2008) Lasers in Surgery and Medicine , vol.40 , Issue.10 , pp. 726-733
    • Hou, J.F.1    Zhang, H.2    Yuan, X.3    Li, J.4    Wei, Y.J.5    Hu, S.S.6
  • 14
    • 27744472328 scopus 로고    scopus 로고
    • In vivo identification of the interaction site of ErbB2 extracellular domain with its autoinhibitor
    • DOI 10.1002/jcp.20409
    • P. Hu J. Feng T. Zhou J. Wang B. Jing M. Yu M. Hu X. Zhang B. Shen N. Guo 2005 In vivo identification of the interaction site of ErbB2 extracellular domain with its autoinhibitor Journal of Cellular Physiology 205 3 335 343 10.1002/jcp.20409 1:CAS:528:DC%2BD2MXht1Shtr7I 15920761 (Pubitemid 41598847)
    • (2005) Journal of Cellular Physiology , vol.205 , Issue.3 , pp. 335-343
    • Hu, P.1    Feng, J.2    Zhou, T.3    Wang, J.4    Jing, B.5    Yu, M.6    Hu, M.7    Zhang, X.8    Shen, B.9    Guo, N.10
  • 15
    • 40949085086 scopus 로고    scopus 로고
    • Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis
    • DOI 10.1016/j.jtcvs.2007.07.071, PII S0022522307016522
    • X. Hu S.P. Yu J.L. Fraser Z. Lu M.E. Ogle J.A. Wang L. Wei 2008 Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis The Journal of Thoracic and Cardiovascular Surgery 135 4 799 808 10.1016/j.jtcvs.2007.07.071 1:CAS:528:DC%2BD1cXlsVehtb4%3D 18374759 (Pubitemid 351417929)
    • (2008) Journal of Thoracic and Cardiovascular Surgery , vol.135 , Issue.4 , pp. 799-808
    • Hu, X.1    Yu, S.P.2    Fraser, J.L.3    Lu, Z.4    Ogle, M.E.5    Wang, J.-A.6    Wei, L.7
  • 16
    • 18644376728 scopus 로고    scopus 로고
    • TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: A critical role of IFN-β as a decision maker
    • 1:CAS:528:DC%2BD2MXjvV2mu7g%3D 15879150
    • D.Y. Jung H. Lee B.Y. Jung J. Ock M.S. Lee W.H. Lee K. Suk 2005 TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-β as a decision maker The Journal of Immunology 174 10 6467 6476 1:CAS:528:DC%2BD2MXjvV2mu7g%3D 15879150
    • (2005) The Journal of Immunology , vol.174 , Issue.10 , pp. 6467-6476
    • Jung, D.Y.1    Lee, H.2    Jung, B.Y.3    Ock, J.4    Lee, M.S.5    Lee, W.H.6    Suk, K.7
  • 17
    • 33745310690 scopus 로고    scopus 로고
    • Intracellular TLR signaling: A structural perspective on human disease
    • 1:CAS:528:DC%2BD28XlvV2ns7k%3D 16785490
    • M.V. Lasker S.K. Nair 2006 Intracellular TLR signaling: a structural perspective on human disease The Journal of Immunology 177 1 11 16 1:CAS:528:DC%2BD28XlvV2ns7k%3D 16785490
    • (2006) The Journal of Immunology , vol.177 , Issue.1 , pp. 11-16
    • Lasker, M.V.1    Nair, S.K.2
  • 19
    • 61349145539 scopus 로고    scopus 로고
    • Oxidative preconditioning promotes bone marrow mesenchymal stem cells migration and prevents apoptosis
    • 10.1016/j.cellbi.2009.01.012 19356708
    • S. Li Y. Deng J. Feng W. Ye 2009 Oxidative preconditioning promotes bone marrow mesenchymal stem cells migration and prevents apoptosis Cell Biology International 33 3 411 418 10.1016/j.cellbi.2009.01.012 19356708
    • (2009) Cell Biology International , vol.33 , Issue.3 , pp. 411-418
    • Li, S.1    Deng, Y.2    Feng, J.3    Ye, W.4
  • 21
    • 65849373134 scopus 로고    scopus 로고
    • Angiopoietin-1 protects mesenchymal stem cells against serum deprivation and hypoxia-induced apoptosis through the PI3K/Akt pathway
    • 10.1111/j.1745-7254.2008.00811.x 18565279
    • X.B. Liu J. Jiang C. Gui X.Y. Hu M.X. Xiang J.A. Wang 2008 Angiopoietin-1 protects mesenchymal stem cells against serum deprivation and hypoxia-induced apoptosis through the PI3K/Akt pathway Acta Pharmacologica Sinica 29 7 815 822 10.1111/j.1745-7254.2008.00811.x 18565279
    • (2008) Acta Pharmacologica Sinica , vol.29 , Issue.7 , pp. 815-822
    • Liu, X.B.1    Jiang, J.2    Gui, C.3    Hu, X.Y.4    Xiang, M.X.5    Wang, J.A.6
  • 22
    • 70349200977 scopus 로고    scopus 로고
    • Lysophosphatidic acid protects mesenchymal stem cells against ischemia-induced apoptosis in vivo
    • 10.1089/scd.2008.0352 1:CAS:528:DC%2BD1MXhtFWhtLfE 19193014
    • X.B. Liu J.F. Hou L.H. Shi J.H. Chen J.L. Sang S.S. Hu X.F. Cong X. Chen 2009 Lysophosphatidic acid protects mesenchymal stem cells against ischemia-induced apoptosis in vivo Stem Cells and Development 18 7 947 954 10.1089/scd.2008.0352 1:CAS:528:DC%2BD1MXhtFWhtLfE 19193014
    • (2009) Stem Cells and Development , vol.18 , Issue.7 , pp. 947-954
    • Liu, X.B.1    Hou, J.F.2    Shi, L.H.3    Chen, J.H.4    Sang, J.L.5    Hu, S.S.6    Cong, X.F.7    Chen, X.8
  • 23
    • 65349135405 scopus 로고    scopus 로고
    • Prolyl hydroxylase inhibitor dimethyloxalylglycine enhances mesenchymal stem cell survival
    • 10.1002/jcb.22064 1:CAS:528:DC%2BD1MXktFKktLw%3D 19229863
    • X.B. Liu J.A. Wang M.E. Ogle L. Wei 2009 Prolyl hydroxylase inhibitor dimethyloxalylglycine enhances mesenchymal stem cell survival Journal of Cellular Biochemistry 106 5 903 911 10.1002/jcb.22064 1:CAS:528: DC%2BD1MXktFKktLw%3D 19229863
    • (2009) Journal of Cellular Biochemistry , vol.106 , Issue.5 , pp. 903-911
    • Liu, X.B.1    Wang, J.A.2    Ogle, M.E.3    Wei, L.4
  • 25
    • 55049135589 scopus 로고    scopus 로고
    • Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney
    • 10.1634/stemcells.2007-1000 1:CAS:528:DC%2BD1cXpvV2mu70%3D 18467662
    • C. Mias E. Trouche M.H. Seguelas F. Calcagno F. Dignat-George F. Sabatier M.D. Piercecchi-Marti L. Daniel P. Bianchi D. Calise, et al. 2008 Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney Stem Cells 26 7 1749 1757 10.1634/stemcells.2007-1000 1:CAS:528:DC%2BD1cXpvV2mu70%3D 18467662
    • (2008) Stem Cells , vol.26 , Issue.7 , pp. 1749-1757
    • Mias, C.1    Trouche, E.2    Seguelas, M.H.3    Calcagno, F.4    Dignat-George, F.5    Sabatier, F.6    Piercecchi-Marti, M.D.7    Daniel, L.8    Bianchi, P.9    Calise, D.10
  • 26
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • 10.1016/0022-1759(83)90303-4 1:STN:280:DyaL2c%2FovFSmtw%3D%3D 6606682
    • T. Mosmann 1983 Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays Journal of Immunological Methods 65 1-2 55 63 10.1016/0022-1759(83)90303-4 1:STN:280:DyaL2c%2FovFSmtw%3D%3D 6606682
    • (1983) Journal of Immunological Methods , vol.65 , Issue.12 , pp. 55-63
    • Mosmann, T.1
  • 27
    • 69749124536 scopus 로고    scopus 로고
    • Structural-thermodynamic relationships of interactions in the N-terminal ATP-binding domain of Hsp90
    • 10.1016/j.jmb.2009.07.041 1:CAS:528:DC%2BD1MXhtFajs7bP 19631219
    • S. Nilapwar E. Williams C. Fu C. Prodromou L.H. Pearl M.A. Williams J.E. Ladbury 2009 Structural-thermodynamic relationships of interactions in the N-terminal ATP-binding domain of Hsp90 Journal of Molecular Biology 392 4 923 936 10.1016/j.jmb.2009.07.041 1:CAS:528:DC%2BD1MXhtFajs7bP 19631219
    • (2009) Journal of Molecular Biology , vol.392 , Issue.4 , pp. 923-936
    • Nilapwar, S.1    Williams, E.2    Fu, C.3    Prodromou, C.4    Pearl, L.H.5    Williams, M.A.6    Ladbury, J.E.7
  • 28
    • 33751038565 scopus 로고    scopus 로고
    • Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation
    • DOI 10.1016/j.ymthe.2006.05.016, PII S1525001606002140
    • N. Noiseux M. Gnecchi M. Lopez-Ilasaca L. Zhang S.D. Solomon A.D. Deb V.J. Zau R.E. Pratt 2006 Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation Molecular Therapy 14 6 840 850 10.1016/j.ymthe.2006.05.016 1:CAS:528:DC%2BD28Xht1Cis7%2FF 16965940 (Pubitemid 44752717)
    • (2006) Molecular Therapy , vol.14 , Issue.6 , pp. 840-850
    • Noiseux, N.1    Gnecchi, M.2    Lopez-Ilasaca, M.3    Zhang, L.4    Solomon, S.D.5    Deb, A.6    Dzau, V.J.7    Pratt, R.E.8
  • 30
    • 38849108184 scopus 로고    scopus 로고
    • Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardium
    • DOI 10.1093/cvr/cvm025
    • Z. Pasha Y. Wang R. Sheikh D. Zhang T. Zhao M. Ashraf 2008 Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardium Cardiovascular Research 77 1 134 142 10.1093/cvr/cvm025 1:CAS:528:DC%2BD1cXitVCrtLg%3D 18006467 (Pubitemid 351195153)
    • (2008) Cardiovascular Research , vol.77 , Issue.1 , pp. 134-142
    • Pasha, Z.1    Wang, Y.2    Sheikh, R.3    Zhang, D.4    Zhao, T.5    Ashraf, M.6
  • 31
    • 33745248672 scopus 로고    scopus 로고
    • Effect of reduced culture temperature on antioxidant defences of mesenchymal stem cells
    • DOI 10.1016/j.freeradbiomed.2006.04.018, PII S0891584906002796
    • A. Stolzing A. Scutt 2006 Effect of reduced culture temperature on antioxidant defences of mesenchymal stem cells Free Radical Biology and Medicine 41 2 326 338 10.1016/j.freeradbiomed.2006.04.018 1:CAS:528:DC%2BD28Xmt1Ortr0%3D 16814114 (Pubitemid 43928506)
    • (2006) Free Radical Biology and Medicine , vol.41 , Issue.2 , pp. 326-338
    • Stolzing, A.1    Scutt, A.2
  • 32
    • 33750714054 scopus 로고    scopus 로고
    • Stressed stem cells: Temperature response in aged mesenchymal stem cells
    • DOI 10.1089/scd.2006.15.478
    • A. Stolzing S. Sethe A.M. Scutt 2006 Stressed stem cells: temperature response in aged mesenchymal stem cells Stem Cells and Development 15 4 478 487 10.1089/scd.2006.15.478 1:CAS:528:DC%2BD28XpsFOku7s%3D 16978051 (Pubitemid 44701167)
    • (2006) Stem Cells and Development , vol.15 , Issue.4 , pp. 478-487
    • Stolzing, A.1    Sethe, S.2    Scutt, A.M.3
  • 33
    • 27744505661 scopus 로고    scopus 로고
    • Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector
    • DOI 10.1016/j.jacc.2005.05.079, PII S0735109705016566
    • Y.L. Tang Y. Tang Y.C. Zhang K. Qian L. Shen M.I. Phillips 2005 Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector Journal of the American College of Cardiology 46 7 1339 1350 10.1016/j.jacc.2005.05.079 1:CAS:528:DC%2BD2MXhtlarsr%2FI 16198853 (Pubitemid 41615559)
    • (2005) Journal of the American College of Cardiology , vol.46 , Issue.7 , pp. 1339-1350
    • Tang, Y.L.1    Tang, Y.2    Zhang, Y.C.3    Qian, K.4    Shen, L.5    Phillips, M.I.6
  • 34
    • 69849107530 scopus 로고    scopus 로고
    • Impact of heat-shock protein 90 on cancer metastasis
    • 10.2217/fon.09.30 1:CAS:528:DC%2BD1MXnt1Gjt70%3D 19519207
    • S. Tsutsumi K. Beebe L. Neckers 2009 Impact of heat-shock protein 90 on cancer metastasis Future Oncology 5 5 679 688 10.2217/fon.09.30 1:CAS:528:DC%2BD1MXnt1Gjt70%3D 19519207
    • (2009) Future Oncology , vol.5 , Issue.5 , pp. 679-688
    • Tsutsumi, S.1    Beebe, K.2    Neckers, L.3
  • 35
  • 36
    • 69949087513 scopus 로고    scopus 로고
    • Anti-apoptotic effect of heat shock protein 90 on hypoxia-mediated cardiomyocyte damage is mediated via the phosphatidylinositol 3-kinase/Akt pathway
    • 10.1111/j.1440-1681.2009.05167.x 1:CAS:528:DC%2BD1MXhtFKksr7I
    • W. Wang Y. Peng Y. Wang X. Zhao Z. Yuan 2009 Anti-apoptotic effect of heat shock protein 90 on hypoxia-mediated cardiomyocyte damage is mediated via the phosphatidylinositol 3-kinase/Akt pathway Clinical and Experimental Pharmacology and Physiology 36 9 899 903 10.1111/j.1440-1681.2009.05167.x 1:CAS:528:DC%2BD1MXhtFKksr7I
    • (2009) Clinical and Experimental Pharmacology and Physiology , vol.36 , Issue.9 , pp. 899-903
    • Wang, W.1    Peng, Y.2    Wang, Y.3    Zhao, X.4    Yuan, Z.5
  • 37
    • 65649150660 scopus 로고    scopus 로고
    • Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl] piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expression
    • 10.1124/jpet.109.150839 1:CAS:528:DC%2BD1MXlt1Omu7c%3D 19218529
    • S. Wisel M. Khan M.L. Kuppusamy I.K. Mohan S.M. Chacko B.K. Rivera B.C. Sun K. Hideg P. Kuppusamy 2009 Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl] piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expression Journal of Pharmacology and Experimental Therapeutics 329 2 543 550 10.1124/jpet.109.150839 1:CAS:528:DC%2BD1MXlt1Omu7c%3D 19218529
    • (2009) Journal of Pharmacology and Experimental Therapeutics , vol.329 , Issue.2 , pp. 543-550
    • Wisel, S.1    Khan, M.2    Kuppusamy, M.L.3    Mohan, I.K.4    Chacko, S.M.5    Rivera, B.K.6    Sun, B.C.7    Hideg, K.8    Kuppusamy, P.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.