Atypical thymic carcinoid associated with cushing's syndrome

Tokai Journal of Experimental and Clinical Medicine

Volumn 35, Issue 2, 2010, Pages 78-84

  Sato, Haruhiro ^a   Kajiya, Hanako ^a   Kanai, Genta ^a   Hirukawa, Takashi ^a   Tanaka, Hisae ^a   Kakuta, Takatoshi ^a   Inomoto, Chie ^a   Osamura, Robert Yoshiyuki ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Atypical thymic carcinoid; Cushing's syndrome; Somatostatin analogue; Somatostatin receptor

Indexed keywords

17 HYDROXYCORTICOSTEROID; CHROMOGRANIN A; CORTICOTROPIN; HYDROCORTISONE; METYRAPONE; NEURON SPECIFIC ENOLASE; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR 2; SYNAPTOPHYSIN;

ADRENALECTOMY; ADULT; ARTICLE; ATYPICAL THYMIC CARCINOID; BLOOD CELL COUNT; BONE METASTASIS; CARCINOID; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; CUSHING SYNDROME; DEXAMETHASONE SUPPRESSION TEST; DISEASE ASSOCIATION; DISEASE SEVERITY; ECTOPIC CORTICOTROPIN PRODUCTION; FAMILY HISTORY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYDROCORTISONE BLOOD LEVEL; HYPERCORTISOLISM; HYPERLIPIDEMIA; HYPERTENSION; HYPOKALEMIA; IMMUNOHISTOCHEMISTRY; LEG EDEMA; LYMPH NODE METASTASIS; MEDIASTINUM TUMOR; PHYSICAL EXAMINATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINUS TACHYCARDIA; SPINE METASTASIS;

ADRENOCORTICOTROPIC HORMONE; CARCINOID TUMOR; CUSHING SYNDROME; DISEASE PROGRESSION; FATAL OUTCOME; FEMALE; HUMANS; MEDIASTINAL NEOPLASMS; MIDDLE AGED; RECEPTORS, SOMATOSTATIN; THYMUS NEOPLASMS;

EID: 77955485388     PISSN: 03850005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Travis W, Petersen I, Nicholson S, et al. Small cell carcinoma. In: Travis WD, Brambilla E, Müller-Hermelink HK et al. eds. Pathology and genetics of tumours of the lung, pleura, thymus and heart. Lyon, France: IARC Press; 2004: 31-34.
2. Caplin ME, Buscombe JR, Hilson AJ, Jones AL, Watkinson AF, Burroughs AK. Carcinoid tumour. Lancet 1998; 352: 799-805.
3. Gibril F, Chen YJ, Schrump DS, Vortmeyer A, Zhuang Z, Lubensky IA, et al. Prospective study of thymic carcinoids in patients with multiple endocrine neoplasia type 1. J Clin Endocrinol Metab 2003; 88: 1066-1081.
4. Finding JW, Raff H. Cushing's syndrome: Important issues in diagnosis and management. J Clin Endocrinol Metab 2006; 91: 3746-3753.
5. Sato H, Kanai G, Kajiwara H, Itoh J, Osamura RY. Small-cell carcinoma of the endometrium presenting as Cushing's syndrome. Endocr J 2010; 57: 31-38.
6. Inomoto C, Sato H, Kanai G, Hirukawa T, Shoji S, Terachi T, et al. Black adrenal adenoma causing preclinical Cushing's syndrome. Tokai J Exp Clin Med 2010; 35: 57-61.
7. Shally AV. Oncological applications of somatostatin analogues. Cancer Res 1988; 48: 6977-6985.
8. Bruno JF, Xu Y, Song J, Berelowitz M. Molecular cloning and functional expression of a brain-specific somatostatin receptor. Proc Natl Acad Sci USA 1992; 89: 11151-11155.
9. Patel YC. Somatostatin and its receptor family. Front Neuroendocrinol 1999; 20: 157-198.
10. Lefebvre H, Jégou S, Leroux P, Dero M, Vaudry H, Kuhn JM. Characterization of the somatostatin receptor subtype in a bronchial carcinoid tumor responsible for Cushing's syndrome. J Clin Endocrinol Metab 1995; 80: 1423-1428.
11. Nakashima M, Takano K, Matsuno A. Analyses of factors influencing the acute effect of octreotide in growth hormone-secreting adenomas. Endocr J 2009 56: 295-304.
12. Oki Y, Inoue T, Imura M, Tanaka T, Genma R, Iwabuchi M, et al. Investigation into the efficacy and safety of octreotide LAR in Japanese patients with acromegaly: Shizuoka study. Endocr J 2009; 56: 1095-1101.
13. Engstrom PF, Lavin PT, Moertel CG, Folsch E, Douglass HO Jr. Streptozocin plus fluorouracil versus doxorubicin therapy for metastatic carcinoid tumor. J Clin Oncol 1984; 2: 1255-1259.
14. Kulke MH, Mayer RJ. Carcinoid tumors. N Engl J Med 1999; 340: 858-868.
15. Reubi JC, Kvols LK, Waser B, Nagorney DM, Heitz PU, Charboneau JW, et al. Detection of somatostatin receptors in surgical and percutaneous needle biopsy samples of carcinoids and islet cell carcinomas. Cancer Res 1990; 50: 5969-5977.
16. Hofland LJ, Lambert SW. The pathophysiological consequences of somatostatin receptor internalization and resistance. Endocr Rev 2003; 24: 28-47.
17. Kvols LK, Moertel CG, O'Connell MJ, Schutt AJ, Rubin J, Hahn RG. Treatment of the malignant carcinoid syndrome: evaluation of a long-acting somatostatin analogue. N Engl J Med 1986; 315: 663-666.
18. Kvols LK. Metastatic carcinoid tumors and the malignant carcinoid syndrome. Ann N Y Acad Sci 1994; 733: 464-470.
19. Lambert SW, van der Lely AJ, de Herder WW, Hofland LJ. Octreotide. N Engl J Med 1996; 334: 246-254.