IGF1, IGFBP1, and IGFBP3 genes and mammographic density: The Multiethnic Cohort

International Journal of Cancer

Volumn 127, Issue 5, 2010, Pages 1115-1123

  Verheus, Martijn ^a   Maskarinec, Gertraud ^a   Woolcott, Christy G ^a   Haiman, Christopher A ^b   Le Marchand, Loïc ^a   Henderson, Brian E ^b   Cheng, Iona ^a   Kolonel, Laurence N ^a  

^a UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Breast cancer; IGF I; Mammographic density; Multiethnic cohort; SNP

Indexed keywords

SOMATOMEDIN C; IGFBP1 PROTEIN, HUMAN; IGFBP3 PROTEIN, HUMAN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 1; TUMOR MARKER;

ADULT; ARTICLE; BREAST CANCER; CAUCASIAN; COHORT ANALYSIS; ETHNICITY; EUROPE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; IMMUNOGLOBULIN GENE; JAPANESE; MAJOR CLINICAL STUDY; MAMMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RACE DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED STATES; BREAST; BREAST TUMOR; CANCER INVASION; CASE CONTROL STUDY; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ETHNIC GROUP; ETHNOLOGY; GENETICS; MIDDLE AGED; PATHOLOGY; PROGNOSIS; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL;

BREAST; BREAST NEOPLASMS; CASE-CONTROL STUDIES; ETHNIC GROUPS; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MAMMOGRAPHY; MIDDLE AGED; NEOPLASM INVASIVENESS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; PROSPECTIVE STUDIES; TUMOR MARKERS, BIOLOGICAL;

EID: 77955481933     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25142     Document Type: Article

References (27)

1. Firth SM, Baxter RC. Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 2002;23:824-54.
2. Hankinson SE, Willett WC, Colditz GA, Hunter DJ, Michaud DS, Deroo B, Rosner B, Speizer FE, Pollak M. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 1998;351:1393-6.
3. Toniolo P, Bruning PF, Akhmedkhanov A, Bonfrer JM, Koenig KL, Lukanova A, Shore RE, Zeleniuch-Jacquotte A. Serum insulin-like growth factor-I and breast cancer. Int J Cancer 2000;88:828-32.
4. Muti P, Quattrin T, Grant BJ, Krogh V, Micheli A, Schunemann HJ, Ram M, Freudenheim JL, Sieri S, Trevisan M, Berrino F. Fasting glucose is a risk factor for breast cancer: a prospective study. Cancer Epidemiol Biomarkers Prev 2002;11:1361-8.
5. Rinaldi S, Peeters PH, Berrino F, Dossus L, Biessy C, Olsen A, Tjonneland A, Overvad K, Clavel-Chapelon F, Boutron-Ruault MC, Tehard B, Nagel G, et al. IGF-I, IGFBP-3 and breast cancer risk in women: The European prospective investigation into cancer and nutrition (EPIC). Endocr Relat Cancer 2006;132:593-605.
6. Schernhammer ES, Holly JM, Hunter DJ, Pollak MN, Hankinson SE. Insulin-like growth factor-I, its binding proteins IGFBP-1 and IGFBP-3), and growth hormone and breast cancer risk in the nurses health study II. Endocr Relat Cancer 2006;132:583-92.
7. Byng JW, Boyd NF, Fishell E, Jong RA, Yaffe MJ. The quantitative analysis of mammographic densities. Phys Med Biol 1994;39:1629-38.
8. Boyd NF, Lockwood GA, Martin LJ, Byng JW, Yaffe MJ, Tritchler DL. Mammographic density as a marker of susceptibility to breast cancer: a hypothesis. IARC Sci Publ 2001;154:163-9.
9. Byrne C, Colditz GA, Willett WC, Speizer FE, Pollak M, Hankinson SE. Plasma insulin-like growth factor (IGF) I. IGF-binding protein 3, and mammographic density. Cancer Res 2000;60:3744-8.
10. Boyd NF, Stone J, Martin LJ, Jong R, Fishell E, Yaffe M, Hammond G, Minkin S. The association of breast mitogens with mammographic densities. Br J Cancer 2002;87:876-82.
11. Diorio C, Pollak M, Byrne C, Masse B, Hebert-Croteau N, Yaffe M, Cote G, Berube S, Morin C, Brisson J. Insulin-like growth factor-I. IGF-binding protein-3, and mammographic breast density. Cancer Epidemiol Biomarkers Prev 2005;14:1065-73.
12. Verheus M, Peeters PH, Kaaks R, Van Noord PA, Grobbee DE, Van Gils CH. Premenopausal insulin-like growth factor-I serum levels and changes in breast density over menopause. Cancer Epidemiol Biomarkers Prev 2007;163:451-7.
13. Maskarinec G, Takata Y, Chen Z, Gram IT, Nagata C, Pagano I, Hayashi K, Arendell L, Skeie G, Rinaldi S, Kaaks R. IGF-I and mammographic density in four geographic locations: a pooled analysis. Int J Cancer 2007;121:1786-92.
14. Aiello EJ, Tworoger SS, Yasui Y, Stanczyk FZ, Potter J, Ulrich CM, Irwin M, McTiernan A. Associations among circulating sex hormones, insulin-like growth factor, lipids, and mammographic density in postmenopausal women. Cancer Epidemiol Biomarkers Prev 2005;146:1411-7.
15. Goodman-Gruen D, Barrett-Connor E. Epidemiology of insulin-like growth factor-I in elderly men and women. The Rancho Bernardo Study. Am J Epidemiol 1997;145:970-6.
16. Johansson M, McKay JD, Wiklund F, Rinaldi S, Verheus M, Van Gils CH, Hallmans G, Balter K, Adami HO, Gronberg H, Stattin P, Kaaks R. Implications for prostate cancer of insulin-like growth factor-I IGF-I) genetic variation and circulating IGF-I levels. J Clin Endocrinol Metab 2007;92:4820-6.
17. Patel AV, Cheng I, Canzian F, Le ML, Thun MJ, Berg CD, Buring J, Calle EE, Chanock S, Clavel-Chapelon F, Cox DG, Dorronsoro M, et al. IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3). PLoS ONE 2008;37:e2578.
18. Tamimi RM, Cox DG, Kraft P, Pollak MN, Haiman CA, Cheng I, Freedman ML, Hankinson SE, Hunter DJ, Colditz GA. Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study. Breast Cancer Res 2007;9:R18.
19. Verheus M, McKay JD, Kaaks R, Canzian F, Biessy C, Johansson M, Grobbee DE, Peeters PH, Van Gils CH. Common genetic variation in the IGF-1 gene, serum IGF-I levels and breast density. Breast Cancer Res Treat 2008;112:109-22.
20. Diorio C, Brisson J, Berube S, Pollak M. Genetic polymorphisms involved in insulin-like growth factor (IGF) pathway in relation to mammographic breast density and IGF levels. Cancer Epidemiol Biomarkers Prev 2008;17:880-8.
21. Maskarinec G, Pagano I, Lurie G, Wilkens LR, Kolonel LN. Mammographic density and breast cancer risk: the multiethnic cohort study. Am J Epidemiol 2005;162:743-52.
22. Cheng I, Penney KL, Stram DO, Le ML, Giorgi E, Haiman CA, Kolonel LN, Pike M, Hirschhorn J, Henderson BE, Freedman ML. Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the Multiethnic Cohort. Cancer Epidemiol Biomarkers Prev 2006;15:1993-7.
23. Setiawan VW, Cheng I, Stram DO, Penney KL, Le Marchand L, Altshuler D, Kolonel LN, Hirschhorn J, Henderson BE, Freedman ML. Igf-I genetic variation and breast cancer: the Multiethnic Cohort. Cancer Epidemiol Biomarkers Prev 2006;15:172-4.
24. Kolonel LN, Henderson BE, Hankin JH, Nomura AM, Wilkens LR, Pike MC, Stram DO, Monroe KR, Earle ME, Nagamine FS. A Multiethnic Cohort in Hawaii and Los Angeles: baseline characteristics. Am J Epidemiol 2000;15;151:346-57.
25. Cheng I, Stram DO, Penney KL, Pike M, Le Marchand L, Kolonel LN, Hirschhorn J, Altshuler D, Henderson BE, Freedman ML. Common genetic variation in IGF1 and prostate cancer risk in the Multiethnic Cohort. J Natl Cancer Inst 2006;98:123-34.
26. Cheng I, DeLellis HK, Haiman CA, Kolonel LN, Henderson BE, Freedman ML, Le ML. Genetic determinants of circulating insulin-like growth factor (IGF)-I, IGF binding protein BP)-1, and IGFBP-3 levels in a multiethnic population. J Clin Endocrinol Metab 2007;92:3660-6.
27. Woolcott CG, Maskarinec G, Haiman CA, Verheus M, Pagano IS, Le Marchand L, Henderson BE, Kolonel LN. The association between breast cancer susceptibility loci and mammographic density: the Multiethnic Cohort. Breast Cancer Res 2009;21;11:R10.