Michael addition of N-sulfinyl metalloenamines to β-trifluoromethyl- α,β-unsaturated ester: An efficient access to chiral 4-trifluoromethyl-2-piperidones

Tetrahedron

Volumn 66, Issue 34, 2010, Pages 6864-6868

  Zhang, Fan ^a   Liu, Zhen Jiang ^a   Liu, Jin Tao ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

Trifluoromethyl , unsaturated ester; 4 Trifluoromethyl 2 piperidone; Asymmetric; Michael addition; N Sulfinyl metalloenamine

Indexed keywords

6 PHENYL 4 (TRIFLUOROMETHYL)PIPERIDIN 2 ONE; ENAMINE; ESTER; ETHYL 5 (BUTANESULFINYLIMINO) 5 (4 CHLOROPHENYL) 3 (TRIFLUOROMETHYL)PENTANOATE; ETHYL 5 (BUTANESULFINYLIMINO) 5 (4 METHOXYPHENYL) 3 (TRIFLUOROMETHYL)PENTANOATE; ETHYL 5 (BUTANESULFINYLIMINO) 5 (4 NITROPHENYL) 3 (TRIFLUOROMETHYL)PENTANOATE; ETHYL 5 (BUTANESULFINYLIMINO) 5 MORPHOLINO 3 (TRIFLUOROMETHYL)PENTANOATE; ETHYL 5 (BUTYLSULFINYLIMINO) 6 METHYL 3 (TRIFLUOROMETHYL)HEPTANOATE; ETHYL 5 (BUTYLSULFINYLIMINO) 6,6 DIMETHYL 3 (TRIFLUOROMETHYL)HEPTANOATE; ETHYL 5 (SULFINYLAMIDO) 5 PHENYL 3 (TRIFLUOROMETHYL)PENTANOATE; ETHYL 5 TERT BUTANESULFINYLIMINO) 5 4 TOLYL 3 (TRIFLUOROMETHYL)PENTANOATE; ETHYL 5 TERT BUTANESULFINYLIMINO) 5 PHENYL 3 (TRIFLUOROMETHYL)PENTANOATE; PIPERIDONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; CYCLIZATION; MICHAEL ADDITION; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

EID: 77955471538     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.06.047     Document Type: Article

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