Age and sex differences, and changing trends, in the use of evidence-based therapies in acute coronary syndromes: Perspectives from a multinational registry

Coronary Artery Disease

Volumn 21, Issue 6, 2010, Pages 336-344

  Nguyen, Hoa L ^a   Goldberg, Robert J ^a   Gore, Joel M ^a   Fox, Keith A A ^c   Eagle, Kim A ^b   Gurfinkel, Enrique P ^d   Spencer, Frederick A ^e   Reed, George ^a   Quill, Ann ^a   Anderson, Frederick A ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

^d HOSPITAL UNIVERSITARIO FUNDACIÓN FAVALORO   (Argentina)

^e MCMASTER UNIVERSITY   (Canada)

Author keywords

acute coronary syndromes; aging; effective cardiac therapies; sex

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ACUTE CORONARY SYNDROME; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; DISEASE REGISTRY; EVIDENCE BASED MEDICINE; FEMALE; GROUPS BY AGE; HEALTH CARE UTILIZATION; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; SEX DIFFERENCE; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; TREND STUDY;

ACUTE CORONARY SYNDROME; ADRENERGIC BETA-ANTAGONISTS; AGE FACTORS; AGED; AGED, 80 AND OVER; ANGIOPLASTY, BALLOON, CORONARY; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ASPIRIN; AUSTRALIA; CARDIOVASCULAR AGENTS; CORONARY ARTERY BYPASS; DRUG THERAPY, COMBINATION; EUROPE; EVIDENCE-BASED MEDICINE; FEMALE; HEALTHCARE DISPARITIES; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INPATIENTS; MALE; MIDDLE AGED; MYOCARDIAL REVASCULARIZATION; NEW ZEALAND; NORTH AMERICA; ODDS RATIO; PLATELET AGGREGATION INHIBITORS; REGISTRIES; RISK ASSESSMENT; RISK FACTORS; SEX FACTORS; SOUTH AMERICA; TIME FACTORS; TREATMENT OUTCOME;

EID: 77955470659     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/MCA.0b013e32833ce07c     Document Type: Article

References (33)

1. Pfeffer MA, Braunwald E, Moyé LA, Basta L, Brown EJ Jr, Cuddy TE, et al.; The SAVE Investigators. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. N Engl J Med 1992; 327:669-677.
2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17 187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 1988; 2:349-360.
3. Yusuf S, Peto R, Lewis J, Collins R, Sleight P. Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis 1985; 27:335-371.
4. Fibrinolytic Therapy Trialists' (FTT) Collaborative Group. Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomized trials of more than 1000 patients. Lancet 1994; 343:311-322.
5. Stenestrand U, Wallentin L. Fibrinolytic therapy in patients 75 years and older with ST-segment-elevation myocardial infarction: one-year follow-up of a large prospective cohort. Arch Intern Med 2003; 163:965-971.
6. Granger CB, Steg PG, Peterson E, López-Sendón J, Van de Werf F, Kline-Rogers E, et al. Medication performance measures and mortality following acute coronary syndromes. Am J Med 2005; 118:858-865.
7. Tran CT, Laupacis A, Mamdani MM, Tu JV. Effect of age on the use of evidence-based therapies for acute myocardial infarction. Am Heart J 2004; 148:834-841.
8. Goldberg RJ, Spencer FA, Yarzebski J, Lessard D, Gore JM, Alpert JS, et al. A 25-year perspective into the changing landscape of patients hospitalized with acute myocardial infarction (the Worcester Heart Attack Study). Am J Cardiol 2004; 94:1373-1378.
9. Goldberg RJ, Yarzebski J, Lessard D, Gore JM. A two-decades (1975- 1995) long experience in the incidence, in-hospital and long-term casefatality rates of acute myocardial infarction: a community-wide perspective. J Am Coll Cardiol 1999; 33:1533-1539.
10. Hochman JS, Tamis JE, Thompson TD,Weaver WD,White HD, Van deWerf F, et al.; Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes IIb Investigators. Sex, clinical presentation, and outcome in patients with acute coronary syndromes. N Engl J Med 1999; 341:226-232.
11. Puletti M, Sunseri L, Curione M, Erba SM, Borgia C. Acute myocardial infarction: sex-related differences in prognosis. Am Heart J 1984; 108:63-66.
12. Bertoni AG, Bonds DE, Lovato J, Goff DC, Brancati FL. Sex disparities in procedure use for acute myocardial infarction in the United States, 1995-2001. Am Heart J 2004; 147:1054-1060.
13. Avezum A, Piegas LS, Goldberg RJ, Brieger D, Stiles MK, Paolini R, et al. Magnitude and prognosis associated with ventricular arrhythmias in patients hospitalized with acute coronary syndromes (from the GRACE Registry). Am J Cardiol 2008; 102:1577-1582.
14. Vaccarino V, Rathore SS,Wenger NK, Frederick PD, Abramson JL, Barron HV, et al. Sex and racial differences in the management of acute myocardial infarction, 1994-2002. N Engl J Med 2005; 353:671-682.
15. Bowker TJ, Turner RM,Wood DA, Roberts TL, Curzen N, Gandhi M, et al. A National Survey of Acute Myocardial Infarction and Ischaemia (SAMII) in the UK: characteristics, management and in-hospital outcome in women compared to men in patients under 70 years. Eur Heart J 2000; 21:1458-1463.
16. Heer T, Schiele R, Schneider S, Gitt AK, Wienbergen H, Gottwik M, et al. Gender differences in acute myocardial infarction in the era of reperfusion (the MITRA registry). Am J Cardiol 2002; 89:511-517.
17. GRACE investigators. Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: a multinational registry of patients hospitalized with acute coronary syndromes. Am Heart J 2001; 141: 190-199.
18. Steg PG, Goldberg RJ, Gore JM, Fox KA, Eagle KA, Flather MD, et al. Baseline characteristics, management practices, and in-hospital outcomes of patients hospitalized with acute coronary syndromes in the Global Registry of Acute Coronary Events (GRACE). Am J Cardiol 2002; 90: 358-363.
19. Granger CB, Goldberg RJ, Dabbous O, Pieper KS, Eagle KA, Cannon CP, et al. Predictors of hospital mortality in the global registry of acute coronary events. Arch Intern Med 2003; 163:2345-2353.
20. Rogers WJ, Canto JG, Lambrew CT, Tiefenbrunn AJ, Kinkaid B, Shoultz DA, et al. Temporal trends in the treatment of over 1.5 million patients with myocardial infarction in the US from 1990-1999: the National Registry of Myocardial Infarction 1, 2 and 3. J Am Coll Cardiol 2000; 36:2056-2063.
21. Antman EM, Anbe DT, Armstrong PW, Bates ER, Green LA, Hand M, et al. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction; a report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of patients with acute myocardial infarction). J Am Coll Cardiol 2004; 44:E1-E211.
22. Braunwald E, Antman EM, Beasley JW, Califf RM, Cheitlin MD, Hochman JS, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction- summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients With Unstable Angina). J Am Coll Cardiol 2002; 40:1366-1374.
23. Van de Werf F, Ardissino D, Betriu A, Cokkinos DV, Falk E, Fox KA, et al. Management of acute myocardial infarction in patients presenting with STsegment elevation. The Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J 2003; 24:28-66.
24. Ruiz-Bailén M, Aguayo de Hoyos E, Ramos-Cuadra JA, Diaz-Castellanos MA, Issa-Khozouz Z, Reina-Toral A, et al. Influence of age on clinical course, management and mortality of acute myocardial infarction in the Spanish population. Int J Cardiol 2002; 85:285-296.
25. Spencer FA, Goldberg RJ, Frederick PD, Malmgren J, Becker RC, Gore JM. Age and the utilization of cardiac catheterization following uncomplicated first acute myocardial infarction treated with thrombolytic therapy (The Second National Registry of Myocardial Infarction [NRMI-2]). Am J Cardiol 2001; 88:107-111.
26. Skolnick AH, Alexander KP, Chen AY, Roe MT, Pollack CV Jr, Ohman EM, et al. Characteristics, management, and outcomes of 5557 patients age Z90 years with acute coronary syndromes: results from the CRUSADE Initiative. J Am Coll Cardiol 2007; 49:1790-1797.
27. Andrikopoulos G, Pipilis A, Goudevenos J, Tzeis S, Kartalis A, Oikonomou K, et al. Epidemiological characteristics, management and early outcome of acute myocardial infarction in Greece: the HELlenic Infarction Observation Study. Hellenic J Cardiol 2007; 48:325-334.
28. Canto JG, Goldberg RJ, Hand MM, Bonow RO, Sopko G, Pepine CJ, et al. Symptom presentation of women with acute coronary syndromes: myth vs. reality. Arch Intern Med 2007; 167:2405-2413.
29. Woods SE, Noble G, Smith JM, Hasselfeld K. The influence of gender in patients undergoing coronary artery bypass graft surgery: an eight-year prospective hospitalized cohort study. J Am Coll Surg 2003; 196:428-434.
30. Mahon NG, McKenna CJ, Codd MB, O'Rorke C, McCann HA, Sugrue DD. Gender differences in the management and outcome of acute myocardial infarction in unselected patients in the thrombolytic era. Am J Cardiol 2000; 85:921-926.
31. Radovanovic D, Erne P, Urban P, Bertel O, Rickli H, Gaspoz JM. Gender differences in management and outcomes in patients with acute coronary syndromes: results on 20 290 patients from the AMIS Plus Registry. Heart 2007; 93:1369-1375.
32. Blomkalns AL, Chen AY, Hochman JS, Peterson ED, Trynosky K, Diercks DB, et al. Gender disparities in the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes: large-scale observations from the CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation of the American College of Cardiology/American Heart Association Guidelines) National Quality Improvement Initiative. J Am Coll Cardiol 2005; 45:832-837.
33. Vaccarino V, Parsons L, Every NR, Barron HV, Krumholz HM. Sex-based differences in early mortality after myocardial infarction. National Registry of Myocardial Infarction 2 Participants. N Engl J Med 1999; 341:217-225.