Aptasensors: A review

Journal of Biomedical Nanotechnology

Volumn 6, Issue 2, 2010, Pages 93-105

  Lim, Y C ^a   Kouzani, A Z ^a   Duan, W ^a  

^a DEAKIN UNIVERSITY   (Australia)

Author keywords

Aptamer; Aptasensor; Electrical; Electrochemical; Immobilization; Mass sensitive; Micromechanical; Optical; Reporter

Indexed keywords

APTAMERS; APTASENSORS; BIOMOLECULAR INTERACTIONS; BIORECEPTORS; ELECTROCHEMICAL IMMOBILIZATION; MICRO-MECHANICAL; NANOMEDICINES; SMALL SIZE; SURFACE IMMOBILIZATION;

BIOTECHNOLOGY; CHEMICAL STABILITY; MEDICAL NANOTECHNOLOGY;

CHEMICAL DETECTION;

APTAMER; APTASENSOR; CARBON NANOTUBE; DIMETICONE; DODECYL SULFATE SODIUM; FERRICYANIDE; FERROCENE; GOLD; GOLD NANOPARTICLE; MERCAPTOETHANOL; METHYLENE BLUE; NONSTRUCTURAL PROTEIN 3; QUANTUM DOT; SELF ASSEMBLED MONOLAYER; THROMBIN; UNCLASSIFIED DRUG;

ACOUSTICS; BINDING AFFINITY; BIOSENSOR; BIOTECHNOLOGY; CHEMICAL STRUCTURE; COLORIMETRY; CONFORMATION; ELECTROCHEMICAL DETECTION; FIELD EFFECT TRANSISTOR; IMPEDANCE; IONIC STRENGTH; LYSOSOME; MOLECULAR INTERACTION; NANOMEDICINE; PHYSICAL CHEMISTRY; REVIEW; SURFACE PLASMON RESONANCE;

APTAMERS, NUCLEOTIDE; BIOSENSING TECHNIQUES; GOLD; HUMANS; NANOTUBES, CARBON; PHYSICOCHEMICAL PHENOMENA; SURFACE PLASMON RESONANCE; SURFACE PROPERTIES; TRANSDUCERS;

EID: 77955456288     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2010.1103     Document Type: Review

References (68)

1. C. Tuerk and L. Gold, Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249, 505 (1990).
2. S. M. Nimjee, C. P. Rusconi, and B. A. Sullenger, Aptamers: An emerging class of therapeutics. Annu. Rev. Medicine 56, 555 (2004).
3. S. D. Jayasena, An emerging class of molecules that rival antibodies in diagnostics. Clin. Chem. 45, 1628 (1999).
4. E. J. Cho, J.-W. Lee, and A. D. Ellington, Applications of aptamers as sensors. Annu. Rev. Anal. Chem. 2, 241 (2009).
5. S. Song, L. Wang, J. Li, C. Fan, and J. Zhao, Aptamer-based biosensors. Trends in Anal. Chem. 27, 108 (2008).
6. M. Z. Itamar Willner, Electronic aptamer-based sensors. Angew. Chem. Int. Ed. 46, 6408 (2007).
7. B. Strehlitz, N. Nikolaus, and R. Stoltenburg, Protein detection with apatmer biosensors. Sensors 8, 4296 (2008).
8. T. Wink, S. J. V. Zuilen, A. Bult, and W. P. V. Bennekom, Self-assembled monolayers for biosensors. Analyst 122,43R (1997).
9. V. Ostatná, H. Vaisocherová, J. Homola, and T. Hianik, Effect of the immobilisation of DNA aptamers on the detection of thrombin by means of surface plasmon resonance. Anal. Bioanal. Chem. 391, 1861 (2008).
10. L. Shen, Z. Chen, Y. Li, P. Jing, S. Xie, S. He, P. He, and Y. Shao, A chronocoulometric aptamer sensor for adenosine monophosphate. Chem. Commun. 2169 (2007).
11. T. M. A. Gronewold, S. Glass, E. Quandt, and M. Famulok, Monitoring complex formation in the blood-coagulation cascade using aptamer-coated SAW sensors. Biosens. Bioelectron. 20, 2044 (2005).
12. A.-E. Radi, J. L. A. Snchez, E. Baldrich, and C. K. O'Sullivan, Reagentless, reusable, ultrasensitive electrochemical molecular beacon aptasensor. J. Amer. Chem. Soc. 128, 117 (2006).
13. A.-E. Radi, J. L. Acero Sanchez, E. Baldrich, and C. K. O'Sullivan, Reusable impedimetric aptasensor. Anal. Chem. 77, 6320 (2005).
14. A. Bini, S. Centi, S. Tombelli, M. Minunni, and M. Mascini, Development of an optical RNA-based aptasensor for C-reactive protein. Anal. Bioanal. Chem. 390, 1077 (2008).
15. H.-M. So, K. Won, Y. H. Kim, B.-K. Kim, B. H. Ryu, P. S. Na, H. Kim, and J.-O. Lee, Single-walled carbon nanotube biosensors using aptamers as molecular recognition elements. J. Amer. Chem. Soc. 127, 11906(2005).
16. K. Maehashi, T. Katsura, K. Kerman, Y. Takamura, K. Matsumoto, and E. Tamiya, Label-free protein biosensor based on aptamer-modified carbon nanotube field-effect transistors. Anal. Chem. 79, 782 (2007).
17. H. Yoon, J.-H. Kim, N. Lee, B.-G. Kim, and J. Jang, A novel sensor platform based on aptamer-conjugated polypyrrole nanotubes for label-free electrochemical protein detection. Chem. Bio. Chem. 9, 634 (2008).
18. R. A. Potyrailo, R. C. Conrad, A. D. Ellington, and G. M. Hieftje, Adapting selected nucleic acid ligands (Aptamers) to biosensors. Anal. Chem. 70, 3419 (1998).
19. D. Ho, K. Falter, P. Severin, and H. E. Gaub, DNA as a force sensor in an aptamer-based biochip for adenosine. Anal. Chem. 81, 3159 (2009).
20. H. Ozaki, A. Nishihira, M. Wakabayashi, M. Kuwahara, and H. Sawai, Biomolecular sensor based on fluorescence-labeled aptamer. Bioorg. Med. Chem. Lett. 16, 4381 (2006).
21. E. Heyduk and T. Heyduk, Nucleic acid-based fluorescence sensors for detecting proteins. Anal. Chem. 77, 1147 (2005).
22. N. Li and C-M. Ho, Aptamer-based optical probes with separated molecular recognition and signal transduction modules. J. Am. Chem. Soc. 130, 2380 (2008).
23. P. Alivisatos, The use of nanocrystals in biological detection. Nat. Biotechnol. 22, 47 (2004).
24. H.-A. Ho and M. Leclerc, Optical sensors based on hybrid aptamer/conjugated polymer complexes. J. Amer. Chem. Soc. 126, 1384 (2004).
25. Y. Wang, H. Wei, B. Li, W. Ren, S. Guo, S. Dong, and E. Wang, SERS opens a new way in aptasensor for protein recognition with high sensitivity and selectivity. Chem. Commun. 5220 (2007).
26. Y. Wang, D. Li, W. Ren, Z. Liu, S. Dong, and E. Wang, Ultra-sensitive colorimetric detection of protein by aptamer-Au nanoparticles conjugates based on a dot-blot assay. Chem. Commun. 2520 (2008).
27. J. Liu, J. H. Lee, and Y. Lu, Quantum dot encoding of aptamer-linked nanostructures for one-pot simultaneous detection of multiple analytes. Anal. Chem. 79, 4120 (2007).
28. B. Li, Y Du, H. Wei, and S. Dong, Reusable, label-free electrochemical aptasensor for sensitive detection of small molecules. Chem. Commun. 3780 (2007).
29. P. Estrela, D. Paul, P. Migliorato, P. K. Ferrigno, W. Ling, and E. Huq, Potentiometric detection of protein interactions with peptide aptamers. Sensors, 2008 IEEE, Lecce, Italy, October (2008).
30. Y. S. Kim, H. S. Jung, T. Matsuura, H. Y. Lee, T. Kawai, and M. B. Gu, Electrochemical detection of 17β-estradiol using DNA aptamer immobilized gold electrode chip. Biosens. Bioelectron. 22, 2525 (2007).
31. M. N. Mir and I. Katakis, Aptamers as elements of bioelectronic devices. Molecular BioSystems 3, 620 (2007).
32. B. R. Baker, R. Y. Lai, M. S. Wood, E. H. Doctor, A. J. Heeger, and K. W. Plaxco, An electronic, aptamer-based small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids. J. Amer. Chem. Soc. 128, 3138 (2006).
33. K. J. Cash, A. J. Heeger, K. W. Plaxco, and Y. Xiao, Optimization of a reusable, DNA pseudoknot-based electrochemical sensor for sequence-specific DNA detection in blood serum. Anal. Chem. 81, 656 (2009).
34. J. Yoshizumi, S. Kumamoto, M. Nakamura, and K. Yamana, Target-induced strand release (TISR) from aptamer-DNA duplex: A general strategy for electronic detection of biomolecules ranging from a small molecule to a large protein. The Analyst 133, 323 (2008).
35. Y. Xiang, M. Xie, R. Bash, J. J. L. Chen, and J. Wang, Ultrasensitive label-free aptamer-based electronic detection. Angew. Chem. 119, 9212 (2007).
36. M. N. Velasco-Garcia and S. Missailidis, New trends in aptamer-based electrochemical biosensors. Gene Therapy and Molecular Biology 13, 1 (2009).
37. O. A. Sadik, A. O. Aluoch, and A. Zhou, Status of biomolecular recognition using electrochemical techniques. Biosens. Bioelectron. 24, 2749 (2008).
38. C. Deng, J. Chen, Z. Nie, M. Wang, X. Chu, X. Chen, X. Xiao, C. Lei, and S. Yao, Impedimetric aptasensor with femtomolar sensitivity based on the enlargement of surface-charged gold nanoparticles. Anal. Chem. 81, 739 (2008).
39. J. A. Hansen, J. Wang, A.-N. Kawde, Y. Xiang, K. V. Gothelf, and G. Collins, Quantum-dot/aptamer-based ultrasensitive multi-analyte electrochemical biosensor. J. Amer. Chem. Soc. 128, 2228 (2006).
40. M. Zayats, Y. Huang, R. Gill, C-A. Ma, and I. Willner, Label-free and reagentless aptamer-based sensors for small molecules. J. Amer. Chem. Soc. 128, 13666 (2006).
41. C. C. Cid, J. Riu, A. Maroto, and F. X. Rius, Ion-sensitive field effect transistors using carbon nanotubes as the transducing layer. The Analyst 133, 1001 (2008).
42. K. S. Kim, H.-S. Lee, J.-A. Yang, M.-H. Jo, and S. K. Hahn, The fabrication, characterization and application of aptamer-functionalized Si-nanowire FET biosensors. Nanotechnology 20, 1 (2009).
43. M. Lohndorf, U. Schlecht, T. M. A. Gronewold, A. Malave, and M. Tewes, Microfabricated high-performance microwave impedance biosensors for detection of aptamer-protein interactions. Appl. Phys. Lett. 87, 243902 (2005).
44. S. J. Lee, B.-S. Youn, J. W. Park, J. H. Niazi, Y. S. Kim, and M. B. Gu, ssDNA aptamer-based surface plasmon resonance biosensor for the detection of retinol binding protein 4 for the early diagnosis of type 2 diabetes. Anal. Chem. 80, 2867 (2008).
45. N. de-los-Santos-Álvarez, M. J. Lobo-Castañón, A. J. Miranda-Ordieres, and P. Tuñón-Blanco, SPR sensing of small molecules with modified RNA aptamers: Detection of neomycin B. Biosens. Bioelectron. 24, 2547 (2009).
46. J. Wang, R. Lv, J. Xu, D. Xu, and H. Chen, Characterizing the interaction between aptamers and human IgE by use of surface plasmon resonance. Anal. Bioanal. Chem. 390, 1059 (2008).
47. C. Yao, Y. Qi, Y. Zhao, Y. Xiang, Q. Chen, and W. Fu, Aptamer-based piezoelectric quartz crystal microbalance biosensor array for the quantification of IgE. Biosens. Bioelectron. 24, 2499 (2009).
48. D. Lee, M. Yoo, H. Seo, Y. Tak, W-G. Kim, K. Yong, S.-W. Rhee, and S. Jeon, Enhanced mass sensitivity of ZnO nanorod-grown quartz crystal microbalances. Sens. Actuators, B: Chem. 135, 444 (2009).
49. K. Länge, B. Rapp, and M. Rapp, Surface acoustic wave biosensors: A review. Anal. Bioanal. Chem. 391, 1509 (2008).
50. T. M. A. Gronewold, Surface acoustic wave sensors in the bioanalytical field: Recent trends and challenges. Anal. Chim. Acta 603, 119 (2007).
51. M. D. Schiensog, T. M. A. Gronewold, M. Tewes, M. Famulok, and E. Quandt, Love-wave biosensor using nucleic acids as ligands. Sens. Actuators, B: Chem. 101, 308 (2004).
52. J. W. Ndieyira, M. Watari, A. D. Barrera, D. Zhou, M. Vogtli, M. Batchelor, M. A. Cooper, T. Strunz, M. A. Horton, C. Abell, T. Rayment, G. Aeppli, and R. A. McKendry, Nanomechanical detection of antibiotic-mucopeptide binding in a model for superbug drug resistance. Nat. Nano 3, 691 (2008).
53. H.-F. Ji, H. Gao, K. R. Buchapudi, X. Yang, X. Xu, and M. K. Schulte, Microcantilever biosensors based on conformational change of proteins. The Analyst 133, 434 (2008).
54. S. K. Vashist, A review of microcantilevers for sensing applications. J. Nanotechnol. Online 3, 1 (2007).
55. G. G. Stoney, The tension of metallic films deposited by electrolysis, Proceedings of the Royal Society of London Series A, 82, 172 (1909).
56. C. A. Savran, S. M. Knudsen, A. D. Ellington, and S. R. Manalis, Micromechanical detection of proteins using aptamer-based receptor molecules. Anal. Chem. 76, 3194 (2004).
57. K. S. Hwang, S.-M. Lee, K. Eom, J. H. Lee, Y-S. Lee, J. H. Park, D. S. Yoon, and T. S. Kim, Nanomechanical microcantilever operated in vibration modes with use of RNA aptamer as receptor molecules for label-free detection of HCV helicase. Biosens. Bioelectron. 23, 459 (2007).
58. S. Li, L. Fu, J. M. Barbaree, and Z. Y. Cheng, Resonance behavior of magnetostrictive micro/milli-cantilever and its application as a biosensor. Sens. Actuators, B: Chem. 137, 692 (2009).
59. T. Hianik, V. Ostatná, M. Sonlajtnerova, and I. Grman, Influence of ionic strength, pH and aptamer configuration for binding affinity to thrombin. Bioelectrochemistry 70, 127 (2007).
60. S. Balamurugan, A. Obubuafo, S. A. Soper, and D. A. Spivak, Surface immobilization methods for aptamer diagnostics applications. Anal. Bioanal. Chem. 390, 1009 (2008).
61. M. Liss, B. Petersen, H. Wolf, and E. Prohaska, An aptamer-based quartz crystal protein biosensor. Anal. Chem. 74, 4488 (2002).
62. A. Bini, M. Minunni, S. Tombelli, S. Centi, and M. Mascini, Analytical performances of aptamer-based sensing for thrombin detection. Anal. Chem. 79, 3016 (2007).
63. Y. Xiao, A. A. Lubin, A. J. Heeger, and K. W. Plaxco, Label-free electronic detection of thrombin in blood serum by using an aptamer-based sensor. Angew. Chem. 117, 5592 (2005).
64. E. Baldrich, A. Restrepo, and C. K. O'Sullivan, Aptasensor development: Elucidation of critical parameters for optimal aptamer performance. Anal. Chem.:A-K (2004).
65. E. E. Ferapontova, E. M. Olsen, and K. V. Gothelf, An RNA aptamer-based electrochemical biosensor for detection of theophylline in serum. J. Amer. Chem. Soc. 130, 4256 (2008).
66. Y. Xiao, A. A. Lubin, A. J. Heeger, and K. W. Plaxco, Label-free electronic detection of thrombin in blood serum by using an aptamer-based sensor 13. Angew. Chem. Int. Ed. 44, 5456 (2005).
67. J. Hwang and S. Nishikawa, Novel approach to analyzing RNA aptamer - protein interactions: Toward further applications of aptamers. J. Biomol. Screening 11, 1 (2006).
68. C. A. Savran, S. M. Knudsen, A. D. Ellington, and S. R. Manalis, Micromechanical detection of proteins using aptamer-based receptor molecules. Anal. Chem. 76, 3194 (2004).