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Volumn 9, Issue 13, 2010, Pages 2481-2482

A20 inhibition of NFκB and inflammation: Targeting E2:E3 ubiquitin enzyme complexes

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; PROTEIN A20; TAX PROTEIN; TUMOR NECROSIS FACTOR; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN CONJUGATING ENZYME 13; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 77955443665     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.13.12269     Document Type: Editorial
Times cited : (27)

References (11)
  • 1
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    • Failure to regulate TNF-induced NFκB and cell death responses in A20-deficient mice
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  • 3
    • 66649127621 scopus 로고    scopus 로고
    • Mutations of multiple genes cause deregulation of NFκB in diffuse large B-cell lymphoma
    • Compagno M, Lim WK, Grunn A, Nandula SV, Brahmachary M, Shen Q, et al. Mutations of multiple genes cause deregulation of NFκB in diffuse large B-cell lymphoma. Nature 2009; 459:717-21.
    • (2009) Nature , vol.459 , pp. 717-721
    • Compagno, M.1    Lim, W.K.2    Grunn, A.3    Nandula, S.V.4    Brahmachary, M.5    Shen, Q.6
  • 4
    • 1642423503 scopus 로고    scopus 로고
    • Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity
    • DOI 10.1042/BJ20031377
    • Evans PC, Ovaa H, Hamon M, Kilshaw PJ, Hamm S, Bauer S, et al. Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity. Biochem J 2004; 378:727-34. (Pubitemid 38406847)
    • (2004) Biochemical Journal , vol.378 , Issue.3 , pp. 727-734
    • Evans, P.C.1    Ovaa, H.2    Hamon, M.3    Kilshaw, P.J.4    Hamm, S.5    Bauer, S.6    Ploegh, H.L.7    Smith, T.S.8
  • 6
    • 38549146936 scopus 로고    scopus 로고
    • Molecular basis for the unique deubiquitinating activity of the NFκB inhibitor A20
    • Lin SC, Chung JY, Lamothe B, Rajashankar K, Lu M, Lo YC, et al. Molecular basis for the unique deubiquitinating activity of the NFκB inhibitor A20. J Mol Biol 2008; 376:526-40.
    • (2008) J Mol Biol , vol.376 , pp. 526-540
    • Lin, S.C.1    Chung, J.Y.2    Lamothe, B.3    Rajashankar, K.4    Lu, M.5    Lo, Y.C.6
  • 7
    • 39449083378 scopus 로고    scopus 로고
    • The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
    • DOI 10.1038/ni1563, PII NI1563
    • Shembade N, Harhaj NS, Parvatiyar K, Copeland NG, Jenkins NA, Matesic LE, et al. The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20. Nat Immunol 2008; 9:254-62. (Pubitemid 351276830)
    • (2008) Nature Immunology , vol.9 , Issue.3 , pp. 254-262
    • Shembade, N.1    Harhaj, N.S.2    Parvatiyar, K.3    Copeland, N.G.4    Jenkins, N.A.5    Matesic, L.E.6    Harhaj, E.W.7
  • 8
    • 61949220270 scopus 로고    scopus 로고
    • The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NFκB signalling
    • Shembade N, Parvatiyar K, Harhaj NS, Harhaj EW. The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NFκB signalling. EMBO J 2009; 28:513-22.
    • (2009) EMBO J , vol.28 , pp. 513-522
    • Shembade, N.1    Parvatiyar, K.2    Harhaj, N.S.3    Harhaj, E.W.4
  • 9
    • 77649225756 scopus 로고    scopus 로고
    • Inhibition of NFκB Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes
    • Shembade N, Ma A, Harhaj EW. Inhibition of NFκB Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes. Science 2010; 327:1135-9.
    • (2010) Science , vol.327 , pp. 1135-1139
    • Shembade, N.1    Ma, A.2    Harhaj, E.W.3
  • 11
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    • The human T-cell leukemia virus type 1 tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-κB activation
    • DOI 10.1128/JVI.01790-07
    • Shembade N, Harhaj NS, Yamamoto M, Akira S, Harhaj EW. The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NFκB activation. J Virol 2007; 81:13735-42. (Pubitemid 350247866)
    • (2007) Journal of Virology , vol.81 , Issue.24 , pp. 13735-13742
    • Shembade, N.1    Harhaj, N.S.2    Yamamoto, M.3    Akira, S.4    Harhaj, E.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.