Accelerated resolution of laser-induced bruising with topical 20% arnica: A rater-blinded randomized controlled trial

British Journal of Dermatology

Volumn 163, Issue 3, 2010, Pages 557-563

  Leu, S ^a   Havey, J ^a   White, L E ^a   Martin, N ^a   Yoo, S S ^a   Rademaker, A W ^a   Alam, M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

arnica; bruise; contusions; postoperative complications; randomized controlled trial; vitamin K

Indexed keywords

ARNICA MONTANA EXTRACT; PETROLATUM; PLACEBO; RETINOL; VITAMIN K GROUP;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MALE; OUTCOME ASSESSMENT; PHOTOGRAPHY; PRIORITY JOURNAL; PULSED DYE LASER; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SKIN BRUISING; TREATMENT DURATION; TREATMENT INDICATION; VISUAL ANALOG SCALE;

ADMINISTRATION, TOPICAL; ADULT; AGED; ARNICA; CONTUSIONS; DOUBLE-BLIND METHOD; EMOLLIENTS; FEMALE; HUMANS; LASERS; MALE; MIDDLE AGED; OBSERVER VARIATION; PETROLATUM; PHOTOGRAPHY; PHYTOTHERAPY; PLANT PREPARATIONS; VITAMIN K; YOUNG ADULT;

EID: 77955443295     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2010.09813.x     Document Type: Article

References (14)

1. Shah NS, Lazarus MC, Bugdodel R. The effects of topical vitamin K in bruising after laser treatment. J Am Acad Dermatol 2002 47:241 244.
2. Kovacs RK, Bodai L, Dobozy A, Kemeny L. Lack of the effect of topical vitamin K on bruising after mechanical injury. J Am Acad Dermatol 2004 50:982 983.
3. Lou WW, Quintana AT, Geronemus RG, Grossman MC. Effects of topical vitamin K and retinol on laser-induced purpura on nonlesional skin. Dermatol Surg 1999 25:942 944.
4. Stamenova PK, Marchetti T, Simeonov I. Efficacy and safety of topical hirudin (Hirudex): a double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci 2001 5:37 42.
5. Seeley BM, Denton AB, Ahn MS, Maas CS. Effect of homeopathic Arnica montana on bruising in face-lifts: results of a randomized, double-blind, placebo controlled clinical trial. Arch Facial Plast Surg 2006 8:54 9.
6. Stevinson C, Devarai VS, Fountain-Barber A et al. Homeopathic arnica for prevention of pain and bruising: randomized placebo-controlled trial in hand surgery. J R Soc Med 2003 96:60 5.
7. Alonso D, Lazarus MC, Baumann L. Effects of topical arnica gel on post-laser treatment bruises. Dermatol Surg 2002 28:686 688.
8. Moore M. Medicinal Plants of the Pacific West. Santa Fe, NM:Red Crane Books, 1993.
9. Cohen SM, Rousseau ME, Robinson EH. Therapeutic use of selected herbs. Holist Nurs Pract 2000 14:59 68.
10. Karow J-H, Hans-Peter ABT, Frohling M, Ackermann H. Efficacy of Arnica montana D4 for healing wounds after hallux valgus surgery compared to diclofenac. J Altern Complement Med 2008 14:17 25.
11. Lussignoli S, Bertani S, Metelmann H et al. Effect of Traumeel S, a homeopathic formulation, on blood induced inflammation in rats. Complement Ther Med 1999 7:225 230.
12. Conforti A, Bellavite P, Bertani S et al. Rat models of acute inflammation: a randomized control study on the effect of homeopathic remedies. BMC Complement Altern Med 2007 7:1 10.
13. Kouzi SA, Nuzum DS. Arnica for bruising and swelling. Am J Health Syst Pharm 2007 64:2434 2443.
14. Wichtl M (ed.). Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis, 3rd edn. Stuttgart:MedPharm, 2004.