Small-molecule-based inhibition of histone demethylation in cells assessed by quantitative mass spectrometry

Journal of Proteome Research

Volumn 9, Issue 8, 2010, Pages 4082-4092

  MacKeen, Mukram M ^a   Kramer, Holger B ^b   Chang, Kai Hsuan ^a   Coleman, Matthew L ^b   Hopkinson, Richard J ^a   Schofield, Christopher J ^a   Kessler, Benedikt M ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

2 oxoglutarate oxygenases; Demethylases; epigenetics; histone demethylation; JMJD2A; mass spectrometry; post translational modifications; proteomics

Indexed keywords

DICARBOXYLIC ACID DERIVATIVE; HISTONE H3; LYSINE;

ARTICLE; CELL PERMEABILIZATION; CONTROLLED STUDY; DEMETHYLATION; EMBRYO; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

CELL LINE; CHROMATOGRAPHY, LIQUID; GENE EXPRESSION REGULATION; HISTONE DEMETHYLASES; HISTONES; HUMANS; IMMUNOBLOTTING; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; LYSINE; MASS SPECTROMETRY; METHYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; PYRIDINES;

EID: 77955442131     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr100269b     Document Type: Article

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