In-vitro antioxidant and in-vivo hepatoprotective activity of Leucas ciliata leaves

Records of Natural Products

Volumn 4, Issue 2, 2010, Pages 124-130

  Qureshi, Mohammad N ^a   Kuchekar, Bhanudansh S ^b   Logade, Nadeem A ^a   Haleem, Majid A ^a  

^a Govt Aided AIT's Institute of Pharmacy   (India)

^b Government College of Pharmacy   (India)

Author keywords

Antioxidant; CCL4; DPPH; Hepatoprotective; Leucas ciliate; Nitric oxide

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ASCORBIC ACID; CARBON TETRACHLORIDE; LEUCAS CILIATA EXTRACT; NITRIC OXIDE; PLANT EXTRACT; SILYMARIN; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANGIOSPERM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; FEMALE; IN VITRO STUDY; IN VIVO STUDY; IRON CHELATION; LEUCAS CILIATA; LIVER INJURY; LIVER PROTECTION; LIVER WEIGHT; MALE; NONHUMAN; PLANT LEAF; RAT;

CILIOPHORA; LEUCAS; RATTUS;

EID: 77955436246     PISSN: None     EISSN: 13076167     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. P. Mahakunakorn, M. Tohda, Y. Murakami, K. Matsumoto and H. Watanabe (2004). Antioxidant and Free radical-scavenging activity of Choto-san and its related constituents. Biol. Pharm. Bull. 27, 38-46.
2. O. Polterait (1997). Antioxidants and free-radical scavengers of natural origin. Current Org. Chem. 1, 415-440.
3. N. J. Miller and C. Rice-Evans (1997). Factors influencing the antioxidant activity determined by the ABTS radical cation assay. Free Rad. Res. 26, 195-199.
4. P. V. Habbu, H. Joshi and B. S. Patil (2007). Potential wound healers from plant origin. Pharmacog. Rev. 2, 271-282.
5. S. R. Hynniewta and Y. Kumar (2008). Herbal remedies among the Khasi traditional healers and village folks in Meghalaya. Indian J. of Traditional Knowledge. 7, 581-586.
6. C. Long and R. Li (2004). Ethnobotanical studies on medicinal plants used by the Red-headed Yao people in Jinping, Yunnan Province. J. of Ethnopharmacol. 90, 389-395.
7. K. Hu, A. Dong, Q. Sun and X. Yao (2001). Bioactivity of 247 Traditional Chinese Medicines against Pyricularia oryzae. Pharmaceutical Biology. 39, 47-53.
8. L. Alan and N. D. Miller (1996). Antioxidant flavonoids: structure, function and clinical usage. Alternative Med. Rev. 1, 103-111.
9. M. S. Blois (1958). Antioxidant determination by the use of stable free radicals. Nature 181, 1199-1200.
10. L. C. Green, D. A. Wagner, J. Glogowski, P. L. Skipper, J. S. Wishnok and S. R. Tannenbaum (1982). Analysis of nitrate, nitrite and (5N) nitrate in biological fluids. Anal. Biochem. 126, 131-138.
11. I. F. F. Benzie and J. J. Strain (1996). The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power" the FRAP assay. Anal. Biochem. 239, 70-76.
12. M. Oyaizu (1986). Study on products of Browning reactions, antioxidative activities of products of browning reaction prepared from glucosamine. Japanese J. Nutr. 44, 307-315.
13. H. C. Wu, H. M. Chen and C. Y. Shiau (2003). Free amino acids and peptides as related to antioxidant properties in protein hydrolysates of mackerel (Scomber austriasicus). Food Res. Int. 36, 949-957.
14. R. Gibanananda and A. H. Sayed (2002). Oxidants, antioxidants and carcinogenesis. Indian J. Exp. Biol. 40, 1213-1232.
15. A. Ialenti, S. Moncada and M. Di Rosa (1993). Modulation of adjuvant arthritis by indigenous Nitric oxide. Brit. J. Pharmacol. 110, 701-706.
16. K. A. Shenoy, S. N. Somayaji, K. L. Bairy (2001). Hepatoprotective effects of Ginkgo biloba against carbon tetrachloride induced hepatic injury in rats. Indian J. Pharmacol. 33, 260-266.
17. R. O. Recknagel, E. A. Glende, J. A. Dolak Jr and R. L. C. Waller (1989). Mechanism of carbon tetrachloride toxicity. Pharmacol. Ther. 43, 139-154.
18. H. Ozbek, S. Ugras, H. Dulger, I. Bayram, I. Tuncer, G. Ozturk and A. Ozturk (2003). Hepatoprotective effect of Foeniculum vulgare essential oil. Fitoterapia 74, 317-319.
19. M. Yoshikawa, T. Morikawa, Y. Kashima, K. Ninomiya and H. Matsuda (2003). Structure of new dammarane-type triterpene saponins from the flower buds of Panax notoginseng and hepatoprotective effects of principal ginseng saponins. J. Nat. Prod. 66, 922-927.
20. N. L. Baek, Y. S. Kim, J. S. Kyung and K. H. Park (1996). Isolation of anti-hepatotoxic agent from the roots of Astragalus membranaceous. Korean J. Pharmacog. 27, 111-116.
21. R. Sallie, J. M. Tredger and R. William (1991). Drug and the liver. Biopharm. Drug Disp. 12, 251-259.
22. Y. Aniya, T. Koyama, C. Miyagi, M. Miyahira, C. Inomata, S. Kinoshita, T. Ichiba (2005). Free radical scavenging and hepatoprotective actions of the medicinal herb, Crassocephalum crepietioides from Okinowa islands. Biol. Pharm. Bul. 28, 19-23.