메뉴 건너뛰기




Volumn 47, Issue 14, 2010, Pages 2314-2322

The C-terminal region of human NFATc2 binds cJun to synergistically activate interleukin-2 transcription

Author keywords

CJun; Interleukin 2; NFAT; Synergy; T cell; Transcription

Indexed keywords

DNA; HETERODIMER; INTERLEUKIN 2; PROTEIN C FOS; PROTEIN C JUN; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT1; TRANSCRIPTION FACTOR NFAT2; UNCLASSIFIED DRUG;

EID: 77955431728     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.05.287     Document Type: Article
Times cited : (17)

References (42)
  • 2
    • 0033730069 scopus 로고    scopus 로고
    • T cell differentiation: a mechanistic view
    • Avni O., Rao A. T cell differentiation: a mechanistic view. Curr. Opin. Immunol. 2000, 12:654-659.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 654-659
    • Avni, O.1    Rao, A.2
  • 3
    • 0032498230 scopus 로고    scopus 로고
    • The enhanceosome and transcriptional synergy
    • Carey M. The enhanceosome and transcriptional synergy. Cell 1998, 92:5-8.
    • (1998) Cell , vol.92 , pp. 5-8
    • Carey, M.1
  • 4
    • 0025349305 scopus 로고
    • A mechanism of synergistic activation of a mammalian gene by GAL4 derivatives
    • Carey M., Lin Y.S., Green M.R., Ptashne M. A mechanism of synergistic activation of a mammalian gene by GAL4 derivatives. Nature 1990, 345:361-364.
    • (1990) Nature , vol.345 , pp. 361-364
    • Carey, M.1    Lin, Y.S.2    Green, M.R.3    Ptashne, M.4
  • 5
    • 0032485391 scopus 로고    scopus 로고
    • Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA
    • Chen L., Glover J.N., Hogan P.G., Rao A., Harrison S.C. Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature 1998, 392:42-48.
    • (1998) Nature , vol.392 , pp. 42-48
    • Chen, L.1    Glover, J.N.2    Hogan, P.G.3    Rao, A.4    Harrison, S.C.5
  • 7
    • 0035971433 scopus 로고    scopus 로고
    • Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity
    • Chinenov Y., Kerppola T.K. Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 2001, 20:2438-2452.
    • (2001) Oncogene , vol.20 , pp. 2438-2452
    • Chinenov, Y.1    Kerppola, T.K.2
  • 8
    • 0023138044 scopus 로고
    • A 275-basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T-cell antigen receptor
    • Durand D.B., Bush M.R., Morgan J.G., Weiss A., Crabtree G.R. A 275-basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T-cell antigen receptor. J. Exp. Med. 1987, 165:395-407.
    • (1987) J. Exp. Med. , vol.165 , pp. 395-407
    • Durand, D.B.1    Bush, M.R.2    Morgan, J.G.3    Weiss, A.4    Crabtree, G.R.5
  • 10
    • 0035888972 scopus 로고    scopus 로고
    • Expression and purification of recombinant human c-Fos/c-Jun that is highly active in DNA binding and transcriptional activation in vitro
    • Ferguson H.A., Goodrich J.A. Expression and purification of recombinant human c-Fos/c-Jun that is highly active in DNA binding and transcriptional activation in vitro. Nucleic Acids Res. 2001, 29:E98.
    • (2001) Nucleic Acids Res. , vol.29
    • Ferguson, H.A.1    Goodrich, J.A.2
  • 11
    • 0035861992 scopus 로고    scopus 로고
    • Kinetic and mechanistic analysis of the RNA polymerase II transcription reaction at the human interleukin-2 promoter
    • Ferguson H.A., Kugel J.F., Goodrich J.A. Kinetic and mechanistic analysis of the RNA polymerase II transcription reaction at the human interleukin-2 promoter. J. Mol. Biol. 2001, 314:993-1006.
    • (2001) J. Mol. Biol. , vol.314 , pp. 993-1006
    • Ferguson, H.A.1    Kugel, J.F.2    Goodrich, J.A.3
  • 12
    • 0026514058 scopus 로고
    • In vitro transcription faithfully reflecting T-cell activation requirements
    • Flanagan W.M., Crabtree G.R. In vitro transcription faithfully reflecting T-cell activation requirements. J. Biol. Chem. 1992, 267:399-406.
    • (1992) J. Biol. Chem. , vol.267 , pp. 399-406
    • Flanagan, W.M.1    Crabtree, G.R.2
  • 13
    • 0022460420 scopus 로고
    • Regulation of human interleukin-2 gene: functional DNA sequences in the 5' flanking region for the gene expression in activated T lymphocytes
    • Fujita T., Shibuya H., Ohashi T., Yamanishi K., Taniguchi T. Regulation of human interleukin-2 gene: functional DNA sequences in the 5' flanking region for the gene expression in activated T lymphocytes. Cell 1986, 46:401-405.
    • (1986) Cell , vol.46 , pp. 401-405
    • Fujita, T.1    Shibuya, H.2    Ohashi, T.3    Yamanishi, K.4    Taniguchi, T.5
  • 14
    • 0024508141 scopus 로고
    • Synergistic activation and repression of transcription by Drosophila homeobox proteins
    • Han K., Levine M.S., Manley J.L. Synergistic activation and repression of transcription by Drosophila homeobox proteins. Cell 1989, 56:573-583.
    • (1989) Cell , vol.56 , pp. 573-583
    • Han, K.1    Levine, M.S.2    Manley, J.L.3
  • 15
    • 0029053852 scopus 로고
    • Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins
    • Hoey T., Sun Y.L., Williamson K., Xu X. Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 1995, 2:461-472.
    • (1995) Immunity , vol.2 , pp. 461-472
    • Hoey, T.1    Sun, Y.L.2    Williamson, K.3    Xu, X.4
  • 16
    • 0141483523 scopus 로고    scopus 로고
    • Transcriptional regulation by calcium, calcineurin, and NFAT
    • Hogan P.G., Chen L., Nardone J., Rao A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev 2003, 17:2205-2232.
    • (2003) Genes Dev , vol.17 , pp. 2205-2232
    • Hogan, P.G.1    Chen, L.2    Nardone, J.3    Rao, A.4
  • 17
    • 0027491776 scopus 로고
    • The T cell transcription factor NFATp is a substrate for calcineurin and interacts with the DNA-binding domains of Fos and Jun
    • Jain J., McCaffrey P.G., Miner Z., Kerppola T.K., Lambert J.N., Verdine G.L., Curran T., Rao A. The T cell transcription factor NFATp is a substrate for calcineurin and interacts with the DNA-binding domains of Fos and Jun. Nature 1993, 365:352-355.
    • (1993) Nature , vol.365 , pp. 352-355
    • Jain, J.1    McCaffrey, P.G.2    Miner, Z.3    Kerppola, T.K.4    Lambert, J.N.5    Verdine, G.L.6    Curran, T.7    Rao, A.8
  • 18
    • 0026596383 scopus 로고
    • Nuclear factor of activated T cells contains Fos and Jun
    • Jain J., McCaffrey P.G., Valge-Archer V.E., Rao A. Nuclear factor of activated T cells contains Fos and Jun. Nature 1992, 356:801-804.
    • (1992) Nature , vol.356 , pp. 801-804
    • Jain, J.1    McCaffrey, P.G.2    Valge-Archer, V.E.3    Rao, A.4
  • 19
    • 0002234929 scopus 로고    scopus 로고
    • Characterization of DNA binding, transcriptional activation, and regulated nuclear association of recombinant human NFATp
    • Kim L.J., Ferguson H.A., Seto A.G., Goodrich J.A. Characterization of DNA binding, transcriptional activation, and regulated nuclear association of recombinant human NFATp. BMC Immunol. 2000, 1:1.
    • (2000) BMC Immunol. , vol.1 , pp. 1
    • Kim, L.J.1    Ferguson, H.A.2    Seto, A.G.3    Goodrich, J.A.4
  • 21
    • 0025318699 scopus 로고
    • How different eukaryotic transcriptional activators can cooperate promiscuously
    • Lin Y.S., Carey M., Ptashne M., Green M.R. How different eukaryotic transcriptional activators can cooperate promiscuously. Nature 1990, 345:359-361.
    • (1990) Nature , vol.345 , pp. 359-361
    • Lin, Y.S.1    Carey, M.2    Ptashne, M.3    Green, M.R.4
  • 22
    • 0023742799 scopus 로고
    • GAL4 derivatives function alone and synergistically with mammalian activators in vitro
    • Lin Y.-S., Carey M.F., Ptashne M., Green M.R. GAL4 derivatives function alone and synergistically with mammalian activators in vitro. Cell 1988, 54:659-664.
    • (1988) Cell , vol.54 , pp. 659-664
    • Lin, Y.-S.1    Carey, M.F.2    Ptashne, M.3    Green, M.R.4
  • 23
    • 0035816647 scopus 로고    scopus 로고
    • C-Jun binds the N terminus of human TAF(II)250 to derepress RNA polymerase II transcription in vitro
    • Lively T.N., Ferguson H.A., Galasinski S.K., Seto A.G., Goodrich J.A. c-Jun binds the N terminus of human TAF(II)250 to derepress RNA polymerase II transcription in vitro. J. Biol. Chem. 2001, 276:25582-25588.
    • (2001) J. Biol. Chem. , vol.276 , pp. 25582-25588
    • Lively, T.N.1    Ferguson, H.A.2    Galasinski, S.K.3    Seto, A.G.4    Goodrich, J.A.5
  • 24
    • 0030012566 scopus 로고    scopus 로고
    • T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFATc2
    • Loh C., Carew J.A., Kim J., Hogan P.G., Rao A. T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFATc2. Mol. Cell. Biol. 1996, 16:3945-3954.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3945-3954
    • Loh, C.1    Carew, J.A.2    Kim, J.3    Hogan, P.G.4    Rao, A.5
  • 25
    • 0030039721 scopus 로고    scopus 로고
    • Mechanisms of transactivation by nuclear factor of activated T cells-1
    • Luo C., Burgeon E., Rao A. Mechanisms of transactivation by nuclear factor of activated T cells-1. J. Exp. Med. 1996, 184:141-147.
    • (1996) J. Exp. Med. , vol.184 , pp. 141-147
    • Luo, C.1    Burgeon, E.2    Rao, A.3
  • 26
    • 0030949834 scopus 로고    scopus 로고
    • Expression of NFAT-family proteins in normal human T cells
    • Lyakh L., Ghosh P., Rice N.R. Expression of NFAT-family proteins in normal human T cells. Mol. Cell. Biol. 1997, 17:2475-2484.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2475-2484
    • Lyakh, L.1    Ghosh, P.2    Rice, N.R.3
  • 27
    • 20644466433 scopus 로고    scopus 로고
    • NFAT proteins: key regulators of T-cell development and function
    • Macian F. NFAT proteins: key regulators of T-cell development and function. Nat. Rev. Immunol. 2005, 5:472-484.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 472-484
    • Macian, F.1
  • 28
    • 0034283018 scopus 로고    scopus 로고
    • Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun
    • Macian F., Garcia-Rodriguez C., Rao A. Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun. EMBO J. 2000, 19:4783-4795.
    • (2000) EMBO J. , vol.19 , pp. 4783-4795
    • Macian, F.1    Garcia-Rodriguez, C.2    Rao, A.3
  • 29
    • 0031204429 scopus 로고    scopus 로고
    • Involvement of Rel, Fos, and Jun proteins in binding activity to the IL-2 promoter CD28 response element/AP-1 sequence in human T cells
    • McGuire K.L., Iacobelli M. Involvement of Rel, Fos, and Jun proteins in binding activity to the IL-2 promoter CD28 response element/AP-1 sequence in human T cells. J. Immunol. 1997, 159:1319-1327.
    • (1997) J. Immunol. , vol.159 , pp. 1319-1327
    • McGuire, K.L.1    Iacobelli, M.2
  • 30
    • 31744440828 scopus 로고    scopus 로고
    • Protein-protein interaction assays: eliminating false positive interactions
    • Nguyen T.N., Goodrich J.A. Protein-protein interaction assays: eliminating false positive interactions. Nat. Methods 2006, 3:135-139.
    • (2006) Nat. Methods , vol.3 , pp. 135-139
    • Nguyen, T.N.1    Goodrich, J.A.2
  • 31
    • 12644271902 scopus 로고    scopus 로고
    • A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1
    • Peterson B.R., Sun L.J., Verdine G.L. A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:13671-13676.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 13671-13676
    • Peterson, B.R.1    Sun, L.J.2    Verdine, G.L.3
  • 32
    • 0037372882 scopus 로고    scopus 로고
    • Asymmetric recognition of nonconsensus AP-1 sites by Fos-Jun and Jun-Jun influences transcriptional cooperativity with NFATc2
    • Ramirez-Carrozzi V., Kerppola T. Asymmetric recognition of nonconsensus AP-1 sites by Fos-Jun and Jun-Jun influences transcriptional cooperativity with NFATc2. Mol. Cell. Biol. 2003, 23:1737-1749.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1737-1749
    • Ramirez-Carrozzi, V.1    Kerppola, T.2
  • 33
    • 0024687774 scopus 로고
    • Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins
    • Ransone L.J., Visvader J., Sassone-Corsi P., Verma I.M. Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins. Genes Dev. 1989, 3:770-781.
    • (1989) Genes Dev. , vol.3 , pp. 770-781
    • Ransone, L.J.1    Visvader, J.2    Sassone-Corsi, P.3    Verma, I.M.4
  • 34
    • 0034442057 scopus 로고    scopus 로고
    • Molecular aspects of T-cell differentiation
    • Rao A., Avni O. Molecular aspects of T-cell differentiation. Br. Med. Bull. 2000, 56:684-969.
    • (2000) Br. Med. Bull. , vol.56 , pp. 684-969
    • Rao, A.1    Avni, O.2
  • 35
    • 0028857929 scopus 로고
    • Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation
    • Rooney J.W., Sun Y.L., Glimcher L.H., Hoey T. Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation. Mol. Cell. Biol. 1995, 15:6299-6310.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6299-6310
    • Rooney, J.W.1    Sun, Y.L.2    Glimcher, L.H.3    Hoey, T.4
  • 36
    • 0023022087 scopus 로고
    • The promoter region of the interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells
    • Siebenlist U., Durand D.B., Bressler P., Holbrook C.A., Norris M., Kamoun M., Kant J.A., Crabtree G.R. The promoter region of the interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells. Mol. Cell. Biol. 1986, 6:3042-3049.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 3042-3049
    • Siebenlist, U.1    Durand, D.B.2    Bressler, P.3    Holbrook, C.A.4    Norris, M.5    Kamoun, M.6    Kant, J.A.7    Crabtree, G.R.8
  • 37
    • 0030860911 scopus 로고    scopus 로고
    • Repression of p53-mediated transcription by MDM2: A dual mechanism
    • Thut C.T., Goodrich J.A., Tjian R. Repression of p53-mediated transcription by MDM2: A dual mechanism. Genes Dev. 1997, 11:1974-1986.
    • (1997) Genes Dev. , vol.11 , pp. 1974-1986
    • Thut, C.T.1    Goodrich, J.A.2    Tjian, R.3
  • 39
    • 0031571716 scopus 로고    scopus 로고
    • Redundant expression but selective utilization of nuclear factor of activated T cells family members
    • Timmerman L.A., Healy J.I., Ho S.N., Chen L., Goodnow C.C., Crabtree G.R. Redundant expression but selective utilization of nuclear factor of activated T cells family members. J. Immunol. 1997, 159:2735-2740.
    • (1997) J. Immunol. , vol.159 , pp. 2735-2740
    • Timmerman, L.A.1    Healy, J.I.2    Ho, S.N.3    Chen, L.4    Goodnow, C.C.5    Crabtree, G.R.6
  • 40
    • 0024535960 scopus 로고
    • Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers
    • Turner R., Tjian R. Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers. Science 1989, 243:1689-1694.
    • (1989) Science , vol.243 , pp. 1689-1694
    • Turner, R.1    Tjian, R.2
  • 41
    • 33947170493 scopus 로고    scopus 로고
    • Characterization of the sequence and architectural constraints of the regulatory and core regions of the human interleukin-2 promoter
    • Weaver J.R., Good K., Walters R.D., Kugel J.F., Goodrich J.A. Characterization of the sequence and architectural constraints of the regulatory and core regions of the human interleukin-2 promoter. Mol. Immunol. 2007, 44:2813-2819.
    • (2007) Mol. Immunol. , vol.44 , pp. 2813-2819
    • Weaver, J.R.1    Good, K.2    Walters, R.D.3    Kugel, J.F.4    Goodrich, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.