Contagious Respiratory Tumours

Diseases of Sheep: Fourth Edition

Volumn , Issue , 2008, Pages 211-216

  Sharp, J M ^a   Heras, M De Las ^b  

^a VETERINARY LABORATORIES AGENCY   (United Kingdom)

^b UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

Adenocarcinoma; Contagious respiratory tumours; Incubation period; Ovine pulmonary adenocarcinoma; Respiratory embarrassment

Indexed keywords

EID: 77955424836     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470753316.ch30     Document Type: Chapter

References (19)

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2. Gonzalez, L. Garcia Goti, M., Cousens, C. et al. (2001) Jaagsiekte sheep retrovirus can be detected in the peripheral blood during the preclinical period of sheep pulmonary adenomatosis, Journal of General Virology, 82, 1355-8.
3. Palmarini, M., Sharp, J.M., De las Heras, M. et al. (1999) Jaagsiekte sheep retrovirus is necessary and sufficient to induce a contagious lung cancer in sheep. Journal of Virology, 73, 6964-72.
4. DeMartini, J.C., Bishop, J.V., Allen, T.E. et al. (2001) Jaagsiekte sheep retrovirus proviral clone JSRVJS7, derived from the JS7 lung tumor cell line, induces ovine pulmonary carcinoma and is integrated into the surfactant protein A gene. Journal of Virology, 75, 4239-46.
5. Danilkovitch-Miagkova, A., Duh, F.M., Kuzmin, I. et al. (2003) Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus. Proceedings of the National Academy of Sciences U.S.A., 100, 4580-5.
6. Wootton, S.K., Halbert, C.L. and Miller, A.D. (2005) Sheep retrovirus structural protein induces lung tumours. Nature, 434, 904-7.
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8. De las Heras, M., Gonzalez, L.G. and Sharp, J.M. (2003) Pathological features of the ovine pulmonary adenocarcinoma. Current Topics in Microbiology and Immunology, 25-54.
9. Nobel, T.A., Neuman F. and Klopfer U. (1969) Histopathological patterns of the metastases in pulmonary adenomatosis of sheep (jaagsiekte). Journal of Comparative Pathology, 79, 537-40.
10. Summers, C., Norval, M., De las Heras, M. et al. (2005) An influx of macrophages is the predominant local immune response in ovine pulmonary adenocarcinoma. Veterinary Immunology and Immunopathology, 106, 285-94.
11. Platt, J., Kraipowich, N., J.C., Villafane, F. et al. (2002) Alveolar type II cells expressing jaagsiekte sheep retrovirus capsid protein and surfactant proteins are the predominant neoplastic cell type in ovine pulmonary adenocarcinoma. Veterinary Pathology, 39, 349-52.
12. Ortin, A., Minguijon, E., Dewar, P. et al. (1998) Lack of a specific immune response against a recombinant capsid protein of Jaagsiekte sheep retrovirus in sheep and goats naturally affected by enzootic nasal tumour or sheep pulmonary adenomatosis. Veterinary Immunology and Immunopathology, 61, 229-37.
13. De las Heras, M., Ortín, A., Salvatori, D. et al. (2005) A PCR technique for the detection of Jaagsiekte sheep retrovirus in the blood suitable for the screening of ovine pulmonary adenocarcinoma in field conditions. Research in Veterinary Science, 79, 259-64.
14. Caporale M., Centorame P., Giovannini A. et al. (2005) Infection of lung epithelial cells and induction of pulmonary adenocarcinoma is not the most common outcome of naturally occurring JSRV infection during the commercial lifespan of sheep. Virology, 338, 144-53.
15. Salvatori, D. (2005) Studies on the pathogenesis and epidemiology of ovine pulmonary adenocarcinoma. PhD thesis, University of Edinburgh.
16. Parker, B.N.J., Wrathall, A.E., Saunders, R.W. et al. (1998) Prevention of transmission of sheep pulmonary adenomatosis by embryo transfer. Veterinary Record, 142, 687-9.
17. De las Heras, M., Minguijon, E., Ortin, A. et al. (1998) Naturally occurring enzootic nasal tumour of sheep in OPA: pathology and associated retrovirus. European Journal of Veterinary Pathology, 4, 11-15.
18. Ortín, A., Pérez de Villarreal, M., Minguijón, E. et al. (2004) Naturally occurring enzootic nasal adenocarcinoma of sheep coexists with Jaagsiekte retrovirus infection. Journal of Comparative Pathology, 131, 253-8.
19. De las Heras, M., Garcia de Jalon, J.A. and Sharp, J.M. (1991) Enzootic nasal tumour of goats: tumour pathology in 38 natural cases. Veterinary Pathology, 28, 474-81.