Ovine bone marrow mesenchymal stem cells: Isolation and characterization of the cells and their osteogenic differentiation potential on embroidered and surface-modified polycaprolactone-co-lactide scaffolds

In Vitro Cellular and Developmental Biology - Animal

Volumn 46, Issue 7, 2010, Pages 624-634

  Rentsch, C ^a   Hess, R ^b   Rentsch, B ^c   Hofmann, A ^b   Manthey, S ^a   Scharnweber, D ^b   Biewener, A ^a   Zwipp, H ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b Max Bergmann Center of Biomaterials   (Germany)

^c Catgut GmbH   (Germany)

Author keywords

Bone marrow; Multilineage differentiation; Ovine mesenchymal stem cells; Polycaprolactone co lactide scaffold; Tissue engineering

Indexed keywords

OSTEOCALCIN; POLYCAPROLACTONE; POLYCAPROLACTONE CO LACTIDE; POLYCAPROLACTONE-CO-LACTIDE; POLYESTER; TISSUE SCAFFOLD;

ADIPOGENESIS; ANIMAL; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE MINERALIZATION; CELL ADHESION; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL SEPARATION; CELL SHAPE; CHEMISTRY; CHONDROGENESIS; CYTOLOGY; DRUG EFFECT; HUMAN; IMMUNOPHENOTYPING; MESENCHYMAL STEM CELL; METABOLISM; METHODOLOGY; SHEEP; STAINING; SURFACE PROPERTY; ULTRASTRUCTURE;

ADIPOGENESIS; ANIMALS; BONE MARROW CELLS; CALCIFICATION, PHYSIOLOGIC; CELL ADHESION; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL SEPARATION; CELL SHAPE; CHONDROGENESIS; HUMANS; IMMUNOPHENOTYPING; MESENCHYMAL STEM CELLS; OSTEOCALCIN; OSTEOGENESIS; POLYESTERS; SHEEP, DOMESTIC; STAINING AND LABELING; SURFACE PROPERTIES; TISSUE SCAFFOLDS;

OVIS; OVIS ARIES;

EID: 77955419148     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11626-010-9316-0     Document Type: Article

References (33)

1. S Bierbaum T Douglas T Hanke D Scharnweber S Tippelt TK Monsees RHW Funk H Worch 2006 Collageneous matrix coating on titanium implants modified with decorin and chondroitin sulfate: Characterization and influence on osteoblastic cells J Biomed Mat Res A 1 77 551 562 10.1002/jbm.a.30572 (Pubitemid 47233580)
2. D Bosnakovski M Mizuno G Kim S Takagi M Okumura T Fujinaga 2005 Isolation and multilineage differentiation of bovine bone marrow mesenchymal stem cells Cell Tissue Res 319 2 243 53 10.1007/s00441-004-1012-5 15654654 (Pubitemid 40174518)
3. H Castano-Izquierdo J Alvarez-Barreto J van den Dolder JA Jansen AG Mikos VI Sikavitsas 2007 Pre-culture period of mesenchymal stem cells in osteogenic media influences their in vivo bone forming potential J Biomed Mater Res A 82 1 129 38 17269144
4. G Chamberlain J Fox B Ashton J Middleton 2007 Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing Stem Cells 25 11 2739 49 10.1634/stemcells.2007-0197 17656645 (Pubitemid 350127858)
5. T Douglas S Heinemann C Mietrach U Hempel S Bierbaum D Scharnweber H Worch 2007 Interactions of collagen types I and II with chondroitin sulfates A-C and their effect on osteoblast adhesion Biomacromolecules 8 4 1085 92 10.1021/bm0609644 17378603 (Pubitemid 46672684)
6. Z Gugala S Gogolewski 2004 Differentiation, growth and activity of rat bone marrow stromal cells on resorbable poly(L/DL-lactide) membranes Biomaterials 25 2299 2307 10.1016/j.biomaterials.2003.09.009 14741595 (Pubitemid 38102385)
7. X Guo C Wang C Duan M Descamps Q Zhao L Dong S Lü K Anselme J Lu YQ Song 2004 Repair of osteochondral defects with autologous chondrocytes seeded onto bioceramic scaffold in sheep Tissue Eng 10 11-12 1830 40 10.1089/ten.2004.10.1830 15684691
8. JO Hollinger J Brekke E Gruskin D Lee 1996 Role of bone substitutes Clin Orthop Relat Res 324 55 65 10.1097/00003086-199603000-00008 8595778
9. JA Hubbell 2003 Materials as morphogenetic guides in tissue engineering Curr Opin Biotechnol 14 5 551 8 10.1016/j.copbio.2003.09.004 14580588 (Pubitemid 37298043)
10. DW Hutmacher 2001 Scaffold design and fabrication technologies for engineering tissue - state of the art and future perspectives J Biomater Sci 12 1 107 124 10.1163/156856201744489 (Pubitemid 32335467)
11. DW Hutmacher JT Schantz CX Lam KC Tan TC Lim 2007 State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective J Tissue Eng Regen Med 1 4 245 60 10.1002/term.24 18038415
12. L Jackson DR Jones P Scotting V Sottile 2007 Adult mesenchymal stem cells: differentiation potential and therapeutic applications J Postgrad Med 53 2 121 7 10.4103/0022-3859.32215 17495381
13. EA Jones SE Kinsey A English RA Jones L Straszynski DM Meredith AF Markham A Jack P Emery D McGonagle 2002 Isolation and characterization of bone marrow multipotential mesenchymal progenitor cells Arthritis Rheum 46 12 3349 60 10.1002/art.10696 12483742 (Pubitemid 35453547)
14. E Kon A Muraglia A Corsi P Bianco M Marcacci I Martin A Boyde I Ruspantini P Chistolini M Rocca R Giardino R Cancedda R Quarto 2000 Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones J Biomed Mater Res 49 3 328 37 10.1002/(SICI)1097-4636(20000305)49:3<328::AID-JBM5>3.0.CO;2-Q 10602065 (Pubitemid 30030478)
15. WJ Li R Tuli X Huang P Laquerriere RS Tuan 2005 Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold Biomaterials 26 25 5158 66 10.1016/j.biomaterials.2005.01. 002 15792543 (Pubitemid 40387839)
16. DR Martin NR Cox TL Hathcock GP Niemeyer HJ Baker 2002 Isolation and characterization of multipotential mesenchymal stem cells from feline bone marrow Exp Hematol 30 8 879 86 10.1016/S0301-472X(02)00864-0 12160839 (Pubitemid 34838890)
17. D Mrugala C Bony N Neves L Caillot S Fabre D Moukoko C Jorgensen D Noël 2008 Phenotypic and functional characterisation of ovine mesenchymal stem cells: application to a cartilage defect model Ann Rheum Dis 67 3 288 95 10.1136/ard.2007.076620 17644536 (Pubitemid 351281260)
18. Neupane M.; Chang C. C.; Kiupel M.; Yuzbasiyan-Gurkan V. Isolation and Characterization of Canine Adipose-Derived Mesenchymal Stem Cells. Tissue Eng Part A Apr 17; 2008.
19. P Perel I Roberts E Sena P Wheble C Briscoe P Sandercock M Macleod LE Mignini P Jayaram KS Khan 2007 Comparison of treatment effects between animal experiments and clinical trials: systematic review BMJ 334 7586 197 10.1136/bmj.39048.407928.BE 17175568 (Pubitemid 46198100)
20. DG Phinney G Kopen RL Isaacson DJ Prockop 1999 Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: variations in yield, growth, and differentiation J Cell Biochem 72 4 570 85 10.1002/(SICI)1097-4644(19990315)72:4<570::AID-JCB12>3.0.CO;2-W 10022616 (Pubitemid 29088308)
21. MF Pittenger AM Mackay SC Beck RK Jaiswal R Douglas JD Mosca MA Moorman DW Simonetti S Craig DR Marshak 1999 Multilineage potential of adult human mesenchymal stem cells Science 284 5411 143 7 10.1126/science.284.5411.143 10102814 (Pubitemid 29282067)
22. S Rammelt T Illert S Bierbaum D Scharnweber H Zwipp W Schneiders 2006 Coating of titanium implants with collagen, RGD peptide and chondroitin sulfate Biomaterials 27 32 5561 71 10.1016/j.biomaterials.2006.06.034 16879866 (Pubitemid 44176146)
23. Rentsch B.; Hofmann A.; Breier A.; Rentsch C.; Scharnweber S. Embroidered and surface modified polycaprolactone-co-lactide scaffolds as bioartificial bone substitute-in vitro characterization. Annals of Biomedical Engineering, In press; 2009.
24. Rentsch C.; Rentsch B.; Breier A.; Hofmann A.; Manthey S.; Scharnweber D.; Biewener A.; Zwipp H. Evaluation of the osteogenic potential and vascularization of 3D poly(3)hydroxybutyrate Scaffolds Subcutaneously Implanted in Nude Rats. Biomed Mater Res A, In press; 2008.
25. J Ringe C Kaps B Schmitt K Büscher J Bartel H Smolian O Schultz GR Burmester T Häupl M Sittinger 2002 Porcine mesenchymal stem cells. Induction of distinct mesenchymal cell lineages Cell Tissue Res 307 3 321 7 10.1007/s00441-002-0525-z 11904768 (Pubitemid 34251597)
26. AJ Salgado OP Coutinho RL Reis 2004 Bone tissue engineering: state of the art and future trends Maccromol Biosci 4 743 765 10.1002/mabi.200400026 (Pubitemid 39257140)
27. Schneiders W.; Reinstorf A.; Ruhnow M.; Rehberg S.; Heineck J.; Hinterseher I.; Biewener A.; Zwipp H.; Rammelt S. Effect of chondroitin sulphate on material properties and bone remodelling around hydroxyapatite/collagen composites. J Biomed Mater Res A; Sep 5; 2007.
28. FW Sutherland TE Perry Y Yu MC Sherwood E Rabkin Y Masuda GA Garcia DL McLellan GC Engelmayr Jr MS Sacks FJ Schoen JE Mayer Jr 2005 From stem cells to viable autologous semilunar heart valve Circulation 111 21 2783 91 10.1161/CIRCULATIONAHA.104.498378 15927990 (Pubitemid 40791550)
29. J Taipale J Keski-Oja 1997 Growth factors in the extracellular matrix FASEB J 11 1 51 9 9034166
30. JLC van Susante J Pieper P Buma TH van Kuppevelt H van Beuningen PM van Der Kraan JH Veerkamp WB van den Berg RPH Veth 2001 Linkage of chondroitin-sulfate to type I collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro Biomaterials 22 17 2359 69 10.1016/S0142-9612(00) 00423-3 11511033 (Pubitemid 32666229)
31. M Wollenweber H Domaschke T Hanke S Boxberger G Schmack K Gliesche D Scharnweber H Worch 2006 Mimicked bioartificial matrix containing chondroitin sulfate on a textile scaffold of poly(3-hydroxybutyrate) alters the differentiation of adult human mesenchymal stem cells Tissue Eng 12 2 345 59 10.1089/ten.2006.12.345 16548693
32. D Woodbury EJ Schwarz DJ Prockop IB Black 2000 Adult rat and human bone marrow stromal cells differentiate into neurons J Neurosci Res 61 4 364 70 10.1002/1097-4547(20000815)61:4<364::AID-JNR2>3.0.CO;2-C 10931522 (Pubitemid 30620221)
33. AA Worster AJ Nixon BD Brower-Toland J Williams 2000 Effect of transforming growth factor beta1 on chondrogenic differentiation of cultured equine mesenchymal stem cells Am J Vet Res 61 9 1003 10 10.2460/ajvr.2000.61. 1003 10976727