Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid

Journal of Experimental Medicine

Volumn 207, Issue 8, 2010, Pages 1637-1646

  Taylor, Rachel E ^a,b,c   Gregg, Christopher J ^a,b,c   Padler Karavani, Vered ^a,b   Ghaderi, Darius ^a,b   Yu, Hai ^e   Huang, Shengshu ^e   Sorensen, Ricardo U ^g   Chen, Xi ^e   Inostroza, Jaime ^f   Nizet, Victor ^d   Varki, Ajit ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSIDAD DE LA FRONTERA   (Chile)

^g LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; IMMUNOLOGICAL ADJUVANT; N GLYCOLOYLNEURAMINIC ACID; N GLYCOLOYLNEURAMINIC ACID ANTIBODY; OLIGOSACCHARIDE; UNCLASSIFIED DRUG; VIRUS ANTIBODY; CARBOHYDRATE DIET; CMPACETYLNEURAMINATE MONOOXYGENASE; GALACTOSE; HETEROPHILE ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LIPID-LINKED OLIGOSACCHARIDES; LIPOPOLYSACCHARIDE; MIXED FUNCTION OXIDASE; N-GLYCOLYLNEURAMINIC ACID; NEURAMINIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ARTICLE; BABY FOOD; CELL SURFACE; CONTROLLED STUDY; FEMALE; HAEMOPHILUS INFLUENZAE; HUMAN; INFANT; MALE; MOUSE; NASOPHARYNX; NEWBORN; NONHUMAN; PRIORITY JOURNAL; ADMINISTRATION AND DOSAGE; ADULT; ANIMAL; BLOOD; C57BL MOUSE; CARBOHYDRATE DIET; GENETICS; HUMORAL IMMUNITY; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; VACCINATION;

ADULT; ANIMALS; ANTIBODIES, HETEROPHILE; AUTOANTIBODIES; DIETARY CARBOHYDRATES; FEMALE; GALACTOSE; HAEMOPHILUS INFLUENZAE; HUMANS; IMMUNITY, HUMORAL; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INFANT; INFANT FOOD; INFANT, NEWBORN; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIXED FUNCTION OXYGENASES; NEURAMINIC ACIDS; VACCINATION;

EID: 77955368995     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20100575     Document Type: Article

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