I'm losing cell viability and function at different points in my process, and I don't know why!

BioProcess International

Volumn 8, Issue 6, 2010, Pages 54-57

  Mathew, Aby J ^a  

^a BioLife Solutions Inc   (United States)

Author keywords

Biopreservation; Critical process parameters (CPPs); Critical quality attributes (CQAs); Modeling; Process optimization; Statistical analysis; Variation

Indexed keywords

ADENOSINE TRIPHOSPHATE; CELSIOR; DIMETHYL SULFOXIDE; UNIVERSITY OF WISCONSIN SOLUTION;

ARTICLE; BIOTECHNOLOGY; BONE MARROW; CELL DAMAGE; CELL FUNCTION; CELL LOSS; CELL MEMBRANE; CELL STRESS; CELL THERAPY; CELL VIABILITY; COLONY FORMING UNIT; COST EFFECTIVENESS ANALYSIS; CRYOPRESERVATION; HAIR CELL; HAIR DISEASE; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; OUTCOME ASSESSMENT; STEM CELL; STORAGE; STORAGE TEMPERATURE;

EID: 77955352738     PISSN: 15426319     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Article

References (6)

1. Clarke DM, et al. Improved Post-Thaw Recovery of Peripheral Blood Stem/Progenitor Cells Using a Novel Intracellular-Like Cryopreservation Solution. Cytotherapy 11(4) 2009: 472-479.
2. Van Buskirk RG, et al. Hypothermic Storage and Cryopreservation: The Issues of Successful Short-Term and Long-Term Preservation of Cells and Tissues. BioProcessing Int. 2(10) 2004: 42-49.
3. Van Buskirk RG, et al. Cryopreservation: It's Not Just About Cell Yield. BioProcess Int. 4(4) 2005.
4. Baust JM. Advances in Media for Cryopreservation and Hypothermic Storage. BioProcess Int. 4(6) 2005: S46-S54.
5. Mathew AJ, et al. Cell Preservation in Reparative and Regenerative Medicine: Evolution of Individualized Solution Composition. Tissue Eng. 10(11-12) 2004: 1662-1671.
6. BioPreservation Today (www.biolifesolutions.com/bpt/bpt.htm).