S-Adenosyl Methionine (SAMe) augmentation in major depressive disorder

American Journal of Psychiatry

Volumn 167, Issue 8, 2010, Pages 889-891

  Nelson, J Craig ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARIPIPRAZOLE; FLUOXETINE; OLANZAPINE; QUETIAPINE; S ADENOSYLMETHIONINE; SEROTONIN UPTAKE INHIBITOR;

ADJUVANT THERAPY; ADULT; BIPOLAR DISORDER; CLINICAL GLOBAL IMPRESSION SCALE; DEPRESSION; DRUG APPROVAL; DRUG COST; DRUG FORMULATION; DRUG LABELING; DRUG SAFETY; DYSTHYMIA; EDITORIAL; EFFECT SIZE; FEMALE; FOOD AND DRUG ADMINISTRATION; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MANIA; MENTAL DISEASE; MONOTHERAPY; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; RECOMMENDED DRUG DOSE; RISK BENEFIT ANALYSIS; SIDE EFFECT; SUSTAINED DRUG RELEASE; SYSTOLIC BLOOD PRESSURE; TREATMENT RESPONSE;

ANTIDEPRESSIVE AGENTS; DEPRESSIVE DISORDER, MAJOR; DRUG COSTS; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; S-ADENOSYLMETHIONINE; TREATMENT OUTCOME;

EID: 77955351653     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2010.10040627     Document Type: Editorial

References (10)

1. Papakostas GI, Mischoulon D, Shyu I, Alpert JE, Fava M: S-Adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial. Am J Psychiatry 2010; 167:942-948
2. Nelson JC, Papakostas GI: Atypical antipsychotic augmentation in major depressive disorder: a meta-analysis of placebo-controlled randomized trials. Am J Psychiatry 2009; 166:980-991
3. Hardy M, Coulter I, Morton SC, Favreau J, Venuturupalli S, Chiappelli F, Rossi F, Orshansky G, Jungvig LK, Roth EA, Suttorp MJ, Shekelle P: S-Adenosyl-L-Methionine for Treatment of Depression, Osteoarthritis, and Liver Disease. Evidence Report/Technology Assessment Number 64. (Prepared by Southern California Evidence-based Practice Center under Contract No. 290-97-001.) AHRQ Publication No. 02-E04. Rockville, Md, Agency for Healthcare Research and Quality, October 2002.
4. Bressa GM: S-adenosyl-L-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl 1994;154:7-14 (Pubitemid 24210857)
5. Fava M, Rosenbaum JF, Birnbarm R, Kelly K, Otto MW, MacLaughlin R: The thyrotropin-releasing hormone as a predictor of response to treatment in depressed outpatients. Acta Psychiatr Scand 1992; 86:42-45
6. Salmaggi P, Bressa GM, Nicchia G, Coniglio M, La Greca P, Le Grazie C: Double-blind, placebo-controlled study of S-adenosyl-L-methionine in depressed post-menopausal women. Psychother Psychosom 1993; 59:34-40 (Pubitemid 23082150)
7. Lu SC: S-Adenosylmethionine. Int J Biochem Cell Biol 2000; 32:391-395
8. Mischoulon D, Fava M: Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Am J Clin Nutr 2002; 76(Nov suppl):1158S-1161S (Pubitemid 35244695)
9. Product review: SAMe (updated 8/17/2007). www.consumerlab.com/results/ Review.asp?reviewid=same (accessed 3/26/2010)
10. Stramentinoli G: Pharmacologic aspects of S-adenosylmethionine: pharmacokinetics and pharmacodynamics. Am J Med 1987; 83:35-42