Triamcinolone-induced cataract in eyes with diabetic macular oedema: 3-year prospective data from a randomized clinical trial

Clinical and Experimental Ophthalmology

Volumn 38, Issue 6, 2010, Pages 605-612

  Gillies, Mark C ^a   Islam, Fakir MA ^b,c   Larsson, Jörgen ^a,d   Pasadhika, Sirichi ^a   Gaston, Chris ^a   Zhu, Meidong ^a   Wong, Tien Y ^b,e  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF SOUTHERN QUEENSLAND   (Australia)

^d LUND UNIVERSITY HOSPITAL   (Sweden)

^e SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

Author keywords

Cataract surgery; IVTA injection; Macular oedema; Visual acuity

Indexed keywords

PLACEBO; TRIAMCINOLONE ACETONIDE; GLUCOCORTICOID; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CATARACT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETIC MACULAR EDEMA; DISEASE COURSE; FEMALE; HUMAN; INCIDENCE; INTRAOCULAR PRESSURE; MAJOR CLINICAL STUDY; MALE; OPEN STUDY; OUTCOME ASSESSMENT; PHACOEMULSIFICATION; PHAKIC INTRAOCULAR LENS; POSTOPERATIVE PERIOD; PROSPECTIVE STUDY; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RETINA MACULA LUTEA; RISK ASSESSMENT; SHAM PROCEDURE; SUBCAPSULAR CATARACT; THICKNESS; TREATMENT OUTCOME; VISUAL ACUITY; CATARACT EXTRACTION; CHEMICALLY INDUCED; CLASSIFICATION; COMPARATIVE STUDY; INJECTION; MACULAR EDEMA; MIDDLE AGED; OPTICAL COHERENCE TOMOGRAPHY; PHYSIOLOGY; RISK FACTOR; STATISTICS AND NUMERICAL DATA; VITREOUS BODY;

AGED; CATARACT; CATARACT EXTRACTION; FEMALE; GLUCOCORTICOIDS; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INJECTIONS; MACULAR EDEMA; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; TOMOGRAPHY, OPTICAL COHERENCE; TRIAMCINOLONE ACETONIDE; VISUAL ACUITY; VITREOUS BODY;

EID: 77955346303     PISSN: 14426404     EISSN: 14429071     Source Type: Journal    
DOI: 10.1111/j.1442-9071.2010.02341.x     Document Type: Article

References (26)

1. Sutter FK, Simpson JM, Gillies MC. Intravitreal triamcinolone for diabetic macular edema that persists after laser treatment: three-month efficacy and safety results of a prospective, randomized, double-masked, placebo-controlled clinical trial. Ophthalmology 2004, 111:2044-9.
2. Jonas JB, Sofker A. Intraocular injection of crystalline cortisone as adjunctive treatment of diabetic macular edema. Am J Ophthalmol 2001, 132:425-7.
3. Jonas JB, Degenring R. Intravitreal injection of crystalline triamcinolone acetonide in the treatment of diffuse diabetic macular oedema. Klin Monatsbl Augenheilkd 2002, 219:429-32.
4. Jonas JB, Kreissig I, Sofker A, Degenring RF. Intravitreal injection of triamcinolone for diffuse diabetic macular edema. Arch Ophthalmol 2003, 121:57-61.
5. Martidis A, Duker JS, Greenberg PB. Intravitreal triamcinolone for refractory diabetic macular edema. Ophthalmology 2002, 109:920-7.
6. Massin P, Audren F, Haouchine B. Intravitreal triamcinolone acetonide for diabetic diffuse macular edema: preliminary results of a prospective controlled trial. Ophthalmology 2004, 111:218-24.
7. Gillies MC, Sutter FKP, Simpson JM, Larsson J, Ali H, Zhu M. Intravitreal Triamcinolone for Refractory Diabetic Macular Oedema: 2-year results of a double-masked, placebo-controlled, randomised clinical trial. Ophthalmology 2006, 113:1533-8.
8. Gillies MC, Simpson JM, Billson FA. Safety of an intravitreal injection of triamcinolone: results from a randomized clinical trial. Arch Ophthalmol 2004, 122:336-40.
9. Bakri SJ, Beer PM. The effect of intravitreal triamcinolone acetonide on intraocular pressure. Ophthalmic Surg Lasers Imaging 2003, 34:386-90.
10. Jonas JB, Kreissig I, Degenring R. Intraocular pressure after intravitreal injection of triamcinolone acetonide. Br J Ophthalmol 2003, 87:24-7.
11. Moshfeghi DM, Kaiser PK, Scott IU. Acute endophthalmitis following intravitreal triamcinolone acetonide injection. Am J Ophthalmol 2003, 136:791-6.
12. Young S, Larkin G, Branley M, Lightman S. Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis. Clin Experiment Ophthalmol 2001, 29:2-6.
13. Antcliff RJ, Poulson A, Flanagan DW. Phacoemulsification in diabetics. Eye 1996, 10:737-41.
14. Dowler JG, Sehmi KS, Hykin PG, Hamilton AM. The natural history of macular edema after cataract surgery in diabetes. Ophthalmology 1999, 106:663-8.
15. Dowler JG, Hykin PG, Hamilton AM. Phacoemulsification versus extracapsular cataract extraction in patients with diabetes. Ophthalmology 2000, 107:457-62.
16. Lam DS, Chan CK, Mohamed S. Phacoemulsification with intravitreal triamcinolone in patients with cataract and coexisting diabetic macular oedema: a 6-month prospective pilot study. Eye 2005, 19:885-90.
17. Jonas JB, Kreissig I, Degenring RF. Cataract surgery after intravitreal injection of triamcinolone acetonide. Eye 2004, 18:361-4.
18. The Age-Related Eye Disease Study (AREDS) system for classifying cataracts from photographs: AREDS report no. 4. Am J Ophthalmol 2001, 131:167-75. Age-Related Eye Disease Study Research Group
19. Gillies MC, Kuzniarz M, Craig J, Ball M, Luo W, Simpson JM. Intravitreal triamcinolone-induced elevated IOP is associated with the development of posterior subcapsular cataract. Ophthalmology 2005, 112:139-43.
20. Wilson CA, Berkowitz BA, Sato Y, Ando N, Handa JT, de Juan E. Treatment with intravitreal steroid reduces blood-retinal barrier breakdown due to retinal photocoagulation. Arch Ophthalmol 1992, 110:1155-9.
21. Alldredge CD, Garretson BR. Intravitreal triamcinolone for the treatment of idiopathic juxtafoveal telangiectasis. Retina 2003, 23:113-16.
22. Antcliff RJ, Spalton DJ, Stanford MR, Graham EM, Ffytche TJ, Marshall J. Intravitreal triamcinolone for uveitic cystoid macular edema: an optical coherence tomography study. Ophthalmology 2001, 108:765-72.
23. Benhamou N, Massin P, Haouchine B, Audren F, Tadayoni R, Gaudric A. Intravitreal triamcinolone for refractory pseudophakic macular edema. Am J Ophthalmol 2003, 135:246-9.
24. Karacorlu M, Mudun B, Ozdemir H, Karacorlu SA, Burumcek E. Intravitreal triamcinolone acetonide for the treatment of cystoid macular edema secondary to Behcet disease. Am J Ophthalmol 2004, 138:289-91.
25. Park CH, Jaffe GJ, Fekrat S. Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion. Am J Ophthalmol 2003, 136:419-25.
26. Sutter FK, Gillies MC. Intravitreal triamcinolone for radiation-induced macular edema. Arch Ophthalmol 2003, 121:1491-3.