Anti-influenza activity of phenethylphenylphthalimide analogs derived from thalidomide

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 14, 2010, Pages 5379-5390

  Iwai, Yuma ^a   Takahashi, Hitoshi ^b   Hatakeyama, Dai ^a   Motoshima, Kazunori ^c   Ishikawa, Minoru ^c   Sugita, Kazuyuki ^c   Hashimoto, Yuichi ^c   Harada, Yuichi ^b   Itamura, Shigeyuki ^b   Odagiri, Takato ^b   Tashiro, Masato ^b   Sei, Yoshihisa ^a   Yamaguchi, Kentaro ^a   Kuzuhara, Takashi ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Endonuclease; Influenza; Phenethylphenylphthalimide; RNA polymerase; Thalidomide

Indexed keywords

3,4 DIHYDROXYPHENETHYL DERIVATIVE; 4,5,6,7 TETRACHLORO N [2 [2 (3,4 DIHYDROXYPHENYL)ETHYL]PHENYL]PHTHALIMIDE; ANTIVIRUS AGENT; COMPLEMENTARY DNA; ENDONUCLEASE; FUNCTIONAL GROUP; N [2 [2 (3,4 DIHYDROXYPHENYL)ETHYL]PHENYL]PHTHALIMIDE; N [3 [2 (3,4 DIHYDROXYPHENYL)ETHYL]PHENYL]PHTHALIMIDE; RECOMBINANT ENZYME; RNA POLYMERASE; RNA POLYMERASE BETA SUBUNIT; RNA POLYMERASE PA SUBUNIT; RNA POLYMERASE PB 2 SUBUNIT; RNA POLYMERASE PB1 SUBUNIT; THALIDOMIDE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS ENZYME;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG SYNTHESIS; DRUG TARGETING; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBUNIT; INFLUENZA; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION; SWINE INFLUENZA VIRUS; VIRUS INHIBITION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DNA-DIRECTED RNA POLYMERASES; DOGS; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; ORTHOMYXOVIRIDAE INFECTIONS; PHTHALIMIDES; STILBENES; THALIDOMIDE;

INFLUENZA A VIRUS; SUIDAE;

EID: 77955334015     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.05.035     Document Type: Article

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