The efficacy of haloperidol in the management of nausea and vomiting in patients with cancer

Journal of Pain and Symptom Management

Volumn 40, Issue 1, 2010, Pages 111-116

  Hardy, Janet R ^a   O'Shea, Angela ^a   White, Clare ^e   Gilshenan, Kristen ^b   Welch, Louise ^c   Douglas, Carol ^d  

^a Mater Health Services   (Austria)

^b MATER HOSPITAL   (Australia)

^c NAMBOUR GENERAL HOSPITAL   (Australia)

^d ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^e NORTHERN IRELAND HOSPICE   (United Kingdom)

Author keywords

Antiemetic; Haloperidol; Nausea; Palliative care; Vomiting

Indexed keywords

DEXAMETHASONE; DOMPERIDONE; DROPERIDOL; GRANISETRON; HALOPERIDOL; LORAZEPAM; METOCLOPRAMIDE; ONDANSETRON; PROCHLORPERAZINE; PROMETHAZINE; ANTIEMETIC AGENT; ANTINEOPLASTIC AGENT;

ADULT; AGED; ARTICLE; BLURRED VISION; CANCER PATIENT; CLINICAL ARTICLE; CONCENTRATION LOSS; CONSTIPATION; DIZZINESS; DROWSINESS; DRUG EFFICACY; DRUG ERUPTION; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; EXTRAPYRAMIDAL SYMPTOM; FEMALE; HEART PALPITATION; HUMAN; MALE; MICTURITION; NAUSEA AND VOMITING; PATIENT ASSESSMENT; RATING SCALE; SCORING SYSTEM; SIDE EFFECT; SKIN IRRITATION; TREATMENT RESPONSE; TREMOR; XEROSTOMIA; CHEMICALLY INDUCED; CLINICAL TRIAL; COMPLICATION; MIDDLE AGED; NAUSEA; NEOPLASMS; ORAL DRUG ADMINISTRATION; PALLIATIVE THERAPY; SUBCUTANEOUS DRUG ADMINISTRATION; TREATMENT OUTCOME; VERY ELDERLY; VOMITING;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; ANTIEMETICS; ANTINEOPLASTIC AGENTS; FEMALE; HALOPERIDOL; HUMANS; INJECTIONS, SUBCUTANEOUS; MALE; MIDDLE AGED; NAUSEA; NEOPLASMS; PALLIATIVE CARE; TREATMENT OUTCOME; VOMITING;

EID: 77955333821     PISSN: 08853924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2009.11.321     Document Type: Article

References (18)

1. D.B. Reuben, and V. Mor Nausea and vomiting in terminal cancer patients Arch Intern Med 146 1986 2021 2023
2. N. Coyle, J. Adelhardt, K.M. Foley, and R.K. Portenoy Character of terminal illness in the advanced cancer patient: pain and other symptoms during the last four weeks of life J Pain Symptom Manage 5 1990 83 93
3. R. Fainsinger, M.J. Miller, E. Bruera, J. Hanson, and T. MacEachern Symptom control during the last week of life on a palliative care unit J Palliat Care 7 1991 5 11
4. C. Conill, E. Verger, and I. Henríquez Symptom prevalence in the last week of life J Pain Symptom Manage 14 1997 328 331
5. P. Edmonds, J. Stuttaford, J. Penny, M.L. Lynch, and J. Chamberlain Do hospital palliative care teams improve symptom control? Use of a modified STAS as an evaluation tool Palliat Med 12 1998 345 351
6. K.A. Mannix Palliation of nausea and vomiting D. Doyle, G.W.C. Hanks, N. MacDonald, Oxford textbook of palliative medicine 1997 Oxford University Press Oxford, UK 489 499
7. R. Twycross Symptom management in advanced cancer 2nd edition 1997 Radcliffe Medical Press Oxford, UK 188-198
8. R. Twycross Guidelines for the management of nausea and vomiting Palliative Care Today 7 1999 32 34
9. P. Glare, D. Dunwoodie, and K. Clark Treatment of nausea and vomiting in terminally ill cancer patients Drugs 68 2008 2575 2590
10. P. Glare, G. Pereira, L. Kristjanson, M. Stockler, and M. Tattersall Systematic review of the efficacy of antiemetics in the treatment of nausea in patients with far-advanced cancer Support Care Cancer 12 2004 432 440
11. A. Kennett, J. Hardy, S. Shah, and R. A'Hern An open study of methotrimeprazine in the management of nausea and vomiting in patients with advanced cancer Support Care Cancer 13 2005 715 721
12. S.J. Peroutka, and S.H. Snyder Antiemetics: neurotransmitter receptor binding predicts therapeutic actions Lancet 1 1982 658 659
13. P. Critchley, N. Plach, and M. Grantham Efficacy of haloperidol in the treatment of nausea and vomiting in the palliative patient: a systematic review J Pain Symptom Manage 22 2001 631 633
14. P. Perkins, and S. Dorman Haloperidol for the treatment of nausea and vomiting in palliative care patients Cochrane Database Syst Rev 2 2009 CD006271
15. M. Buttner, B. Walder, E. von Elm, and M. Tramer Is low dose haloperidol a useful antiemetic? A meta-analysis of published and unpublished randomised trials Anesthesiology 101 2004 1454 1463
16. C. White, J. Hardy, K. Gilshenan, M. Charles, and R. Pinkerton Randomized controlled trials of palliative care - a survey of the views of advanced cancer patients and their relatives Eur J Cancer 44 2008 1820 1828
17. J. Ling, E. Rees, and J. Hardy What influences participation in clinical trials in palliative care in a cancer centre? Eur J Cancer 36 2000 621 626
18. D. Rowett, P. Ravenscroft, J. Hardy, and D. Currow Using national health policies to improve access to palliative care medications in the community J Pain Symptom Manage 37 2009 395 402