Protective effects of methanolic extract of Hedyotis puberula (G. Don) R. Br. ex Arn. against experimentally induced gastric ulcers in rat

Journal of Ethnopharmacology

Volumn 131, Issue 1, 2010, Pages 216-219

  Joseph, Jince Mary ^a   Sowndhararajan, Kandhasamy ^a   Manian, Sellamuthu ^a  

^a BHARATHIAR UNIVERSITY   (India)

Author keywords

Antiulcer; Gastric secretion; Hedyotis puberula; Indomethacin; Pyloric ligation

Indexed keywords

HEDYOTIS PUBERULA EXTRACT; HERBACEOUS AGENT; INDOMETACIN; OMEPRAZOLE; PEPSIN A; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HEDYOTIS; MALE; MOUSE; NONHUMAN; RAT; STOMACH MUCUS; STOMACH PH; STOMACH PROTECTION; STOMACH SECRETION; STOMACH ULCER;

ANIMALS; ANTI-ULCER AGENTS; DISEASE MODELS, ANIMAL; GASTRIC JUICE; HEDYOTIS; MALE; METHANOL; MICE; PLANT EXTRACTS; PLANT STRUCTURES; PROTECTIVE AGENTS; RATS; RATS, WISTAR; STOMACH ULCER;

HEDYOTIS; RATTUS;

EID: 77955318513     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.06.010     Document Type: Article

References (29)

1. Belaiche J., Burette A., De Vos M., Louis E., Huybrechts M., Deltenre M. Study Group of NSAID-GI Complications. Observational survey of NSAID-related upper gastro-intestinal adverse events in Belgium. Acta Gastroenterologia 2002, 65:65-73.
2. Borrelli F., Izzo A.A. The plant kingdom as a source of anti-ulcer remedies. Phtotherapy Research 2000, 14:581-591.
3. Debnath P.K., Gode K.D., Govinda D., Sanyal A.K. Effect of propranolol and gastric secretion in albino rats. Brazilian Journal of Pharmacology 1974, 51:213-216.
4. Di Carlo G., Mascolo N., Izzo A., Capasso F. Flavonoids: old and new aspects of a class of natural therapeutic drugs. Life Sciences 1999, 65:337-353.
5. Dische Z., Barenfreund E. A spectrophotometric method for the microdetermination of hexosamines. Journal of Biological Chemistry 1950, 184:517-522.
6. Dische Z., Schettles L.B. A specific colour reaction for methyl pentoses and a spectrophotometric micromethod for their determination. Journal of Biological Chemistry 1948, 175:595-603.
7. Djahanguiri B. The production of gastric ulceration by indomethacin in the rat. Scandinavian Journal of Gastroenterology 1969, 4:265-267.
8. Dunnett C.W. New tables for multiple comparison with control. Biometrics 1964, 20:484-494.
9. Goel R.K., Govinda Das D., Sanyal A.K. Effect of vegetable banana powder on changes induced by ulcerogenic agents on dissolved mucosubstances in gastric ulceration. Indian Journal of Gastroenterology 1985, 4:249-251.
10. Guth P.H., Paulsen G., Nagata H. Histologic and microcirculatory changes in alcohol-induced gastric lesions in the rat: effect of prostaglandin cytoprotetion. Gastroenterology 1984, 87:1083-1090.
11. Hawk P.B., Oser B.L., Summerson W.H. Practical Physiological Chemistry 1947, Mc Graw-Hill Book Company, New York, p. 375. 13th ed.
12. Hayllar J., Bjarnason I. NSAIDs, Cox-2 inhibitors, and the gut. Lancet 1995, 346:521-522.
13. Hiruma-Lima C.A., Gracioso J.S., Bighetti E.J., Grassi-Kassisse D.M., Nunes D.S., Souza Brito A.R. Effect of essential oil obtained from Croton cajucara Benth. on gastric ulcer healing and protective factors of the gastric mucosa. Phytomedicine 2002, 9:523-529.
14. Hoogerwerf W.A., Pasricha P.J. Agents used for the control of gastric acidity and treatment of peptic ulcers and gastrooesophageal reflux diseases. Goodman and Gilman's: The Pharmacological Basis of Therapeutics 2001, McGraw-Hill, New York, pp. 1005-1019. 10th ed. J.G. Hardman, L.E. Limbri, C.S. Goodman, B.T. Gilman (Eds.).
15. Jiang W., Kuang L.S., Hou A.J., Qian M., Li J.Z. Iridoid glycosides from Hedyotis corymbosa. Helvetica Chimica 2007, 90:1296-1301.
16. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the folin phenol reagent. Journal of Biological Chemistry 1951, 193:265-275.
17. Menguy R., Desbaillets L. The gastric mucosal barrier: Influence of protein bound carbohydrate in mucin on the rat proteolysis of gastric mucus. Annals of Surgery 1968, 168:475-482.
18. Mizui T., Sato H., Hirose F., Doteuchi M. Effect of antiperoxidative drugs on gastric damage induced by ethanol in rats. Life Sciences 1987, 41:755-763.
19. Morimoto Y., Shimohara K., Oshima S., Sukamoto T. Effects of the new anti-ulcer agent KB-5492 on experimental gastric mucosal leisons and gastric mucosal defensive factors, as compared to those of therenone and cimetidine. Japanese Journal of Pharmacology 1991, 57:495-505.
20. Osakabe N., Sanbongi C., Yamagishi M., Takizawa T., Osawa T. Effects of polyphenol substances derived from Theobroma cacao on gastric mucosal lesion induced by ethanol. Bioscience, Biotechnology and Biochemistry 1998, 62:1535-1538.
21. Peng J.N., Feng X., Liang X.T. Iridoids from Hedyotis hedyotidea. Phytochemistry 1998, 47:1657-1659.
22. Peskar B.M., Lange K., Hoppe U., Peskar B.A. Ethanol stimulates formation of leukotriene C4 in rat gastric mucosa. Prostaglandins 1986, 31:283-293.
23. Rao Ch.V., Sairam K., Goel R.K. Experimental evaluation of Bacopa monniera on rat gastric ulceration and secretion. Indian Journal of Physiology and Pharmacology 2000, 44:35-41.
24. Sanyal A.K., Mitra P.K., Goel R.K.A. A modified method to estimate dissolved mucosubstance in gastric juice. Indian Journal of Experimental Biology 1983, 21:78-80.
25. Shay M., Komarov S.A., Fels D., Meranze D., Guenstein H., Siplet H. A simple method for the uniform production of gastric ulceration in the rat. Gastroenterology 1945, 5:43-61.
26. Suzuki Y., Ishihara M., Segami T., Ito M. Anti-ulcer effects of antioxidants quercetin alpha-tocopherol nifedipine and tetracycline in rats. Japanese Journal of Pharmacology 1998, 78:435-441.
27. Wallace J.L. Mechanisms of protection and healing: current knowledge and future research. American Journal of Medicine 2001, 110:19S-22S.
28. Warren L. The thiobarbituric acid assay of sialic acids. Journal of Biological Chemistry 1959, 234:1971-1975.
29. Winzler R.J. Determination of serum glycoproteins. Methods of Biochemical Analalysis 1958, 2:279-281.