Intrinsic activation of GABAA receptors suppresses epileptiform activity in the cerebral cortex of immature mice

Epilepsia

Volumn 51, Issue 8, 2010, Pages 1483-1492

  Richter, Daniel ^a   Luhmann, Heiko J ^a   Kilb, Werner ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Benzodiazepine pharmacology; Development; Field potential recording; GABA uptake; Tiagabine

Indexed keywords

1 [2 [TRIS(4 METHOXYPHENYL)METHYL]ETHYL] 3 PIPERIDINECARBOXYLIC ACID; 3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID CARRIER; 4 AMINOBUTYRIC ACID CARRIER 1; 4 AMINOBUTYRIC ACID CARRIER 2; 4 AMINOBUTYRIC ACID CARRIER 3; 4 AMINOPYRIDINE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; MAGNESIUM ION; MIDAZOLAM; PHENOBARBITAL; PICROTOXIN; PROTEIN INHIBITOR; TIAGABINE; UNCLASSIFIED DRUG; ZOLPIDEM; 1-(2-(TRIS(4-METHOXYPHENYL)METHOXY)ETHYL)-3-PIPERIDINECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; AMINO ACID RECEPTOR BLOCKING AGENT; ANISOLE DERIVATIVE; ENZYME INHIBITOR; MAGNESIUM; NIPECOTIC ACID DERIVATIVE; POTASSIUM CHANNEL BLOCKING AGENT; PYRIDAZINE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; DOSE RESPONSE; ENCEPHALE ISOLE; EPILEPTIC DISCHARGE; IN VITRO STUDY; MEMBRANE DEPOLARIZATION; MOUSE; NEOCORTEX; NERVE CELL MEMBRANE POTENTIAL; NEWBORN; NEWBORN PERIOD; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN FUNCTION; PYRAMIDAL NERVE CELL; RECEPTOR BINDING; RECEPTOR BLOCKING; RECEPTOR INTRINSIC ACTIVITY; REGULATORY MECHANISM; ACTION POTENTIAL; ANIMAL; BRAIN CORTEX; C57BL MOUSE; DRUG EFFECTS; DRUG INTERACTION; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; PROCEDURES;

4-AMINOPYRIDINE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; ANISOLES; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GABA AGONISTS; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION; MAGNESIUM; MICE; MICE, INBRED C57BL; NIPECOTIC ACIDS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; PYRIDAZINES; RECEPTORS, GABA-A; IN VITRO TECHNIQUES;

EID: 77955316629     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2010.02591.x     Document Type: Article

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