The very limited usefulness of skin testing with penicilloyl-polylysine and the minor determinant mixture in evaluating nonimmediate reactions to penicillins

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 65, Issue 9, 2010, Pages 1104-1107

  Romano, A ^a,b   Gaeta, F ^a   Valluzzi, R L ^a   Caruso, C ^a   Rumi, G ^a   Bousquet, P J ^c,d  

^a Allergy Unit   (Italy)

^b OASI RESEARCH INSTITUTE IRCCS   (Italy)

^c GHU Caremeau   (France)

^d HÔPITAL ARNAUD DE VILLENEUVE   (France)

Author keywords

nonimmediate reactions; penicillins; skin tests

Indexed keywords

AMINOPENICILLIN; AMOXICILLIN; AMPICILLIN; BACAMPICILLIN; BENZATHINE PENICILLIN; CEFALEXIN; CEFTRIAXONE; DIAGNOSTIC AGENT; MINOR DETERMINANT MIXTURE; PENICILLIN DERIVATIVE; PENICILLIN G; PENICILLOYL POLYLYSINE; PIPERACILLIN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL FEATURE; DRUG HYPERSENSITIVITY; ERYTHEMA; FEMALE; HUMAN; INTRACUTANEOUS TEST; MACULOPAPULAR RASH; MAJOR CLINICAL STUDY; MALE; PATCH TEST; PRIORITY JOURNAL; SKIN TEST;

ADOLESCENT; ADULT; AGED; BENZENEACETAMIDES; DRUG HYPERSENSITIVITY; FEMALE; HUMANS; HYPERSENSITIVITY, DELAYED; HYPERSENSITIVITY, IMMEDIATE; MALE; MIDDLE AGED; PATCH TESTS; PENICILLANIC ACID; PENICILLINS; POLYLYSINE; SKIN TESTS; YOUNG ADULT;

EID: 77955314673     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2009.02318.x     Document Type: Article

References (12)

1. Executive summary of disease management of drug hypersensitivity: a practice parameter. Joint Task Force on Practice Parameters, the American Academy of Allergy, Asthma and Immunology, the American Academy of Allergy, Asthma and Immunology, and the Joint Council of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol 1999 83 : 665 700.
2. Torres MJ, Blanca M, Fernandez J, Romano A, de Weck A, Aberer W et al. Diagnosis of immediate reactions to beta-lactam antibiotics. Allergy 2003 58 : 961 972. (Pubitemid 37260337)
3. Romano A, Blanca M, Torres MJ, Bircher A, Aberer W, Brockow K et al. Diagnosis of non-immediate reactions to β-lactam antibiotics. Allergy 2004 39 : 1153 1160.
4. Blanca M, Romano A, Torres MJ, Férnandez J, Mayorga C, Rodriguez J et al. Update on the evaluation of hypersensitivity reactions to betalactams. Allergy 2009 64 : 183 193.
5. Torres MJ, Blanca M and the European Network for Drug Allergy (ENDA) and the EAACI interest group on drug hypersensitivity. Importance of skin testing with major and minor determinants of benzylpenicillin in the diagnosis of allergy to betalactams. Statement from the European Network for Drug Allergy concerning AllergoPen withdrawal. Allergy 2006 61 : 910 911.
6. Torres MJ, Romano A, Mayorga C, Moya MC, Guzman AE, Reche M et al. Diagnostic evaluation of a large group of patients with immediate allergy to penicillins: the role of skin testing. Allergy 2001 56 : 850 856.
7. Romano A, Bousquet-Rouanet L, Viola M, Gaeta F, Demoly P, Bousquet PJ. Benzylpenicillin skin testing is still important in diagnosing immediate reactions to penicillins. Allergy 2009 64 : 249 253.
8. Romano A, Viola M, Mondino C, Pettinato R, Di Fonso M, Papa G et al. Diagnosing nonimmediate reactions to penicillins by in vivo tests. Int Arch Allergy Immunol 2002 129 : 169 174.
9. Torres MJ, Sánchez-Sabaté E, Álvarez J, Mayorga C, Fernández J, Padial A et al. Skin test evaluation in nonimmediate allergic reactions to penicillins. Allergy 2004 59 : 219 224.
10. Schiavino D, Nucera E, Lombardo C, Decinti M, Pascolini L, Altomonte G et al. Cross-reactivity and tolerability of imipenem in patients with delayed-type, cell-mediated hypersensitivity to beta-lactams. Allergy 2009 64 : 1644 1648.
11. Romano A, Quaratino D, Di Fonso M, Papa G, Venuti A, Gasbarrini G. A diagnostic protocol for evaluating nonimmediate reactions to aminopenicillins. J Allergy Clin Immunol 1999 103 : 1186 1190.
12. Brockow K, Romano A, Blanca M, Ring J, Pichler W, Demoly P. General considerations for skin test procedures in the diagnosis of drug hypersensitivity. Allergy 2002 57 : 45 51.