메뉴 건너뛰기




Volumn 19, Issue 12, 2010, Pages 2497-2506

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts

(17)  Kalsi, Gursharan a   Kuo, Po Hsiu b   Aliev, Fazil a,c   Alexander, Jeffry a   McMichael, Omari a   Patterson, Diana G d   Walsh, Dermot e   Zhao, Zhongming f   Schuckit, Marc g   Nurnberger, John Jr h   Edenberg, Howard i   Kramer, John j   Vladimirov, Vladimir a   Prescott, Carol A k   Dick, Danielle M a   Kendler, Kenneth S a   Riley, Brien P a  


Author keywords

[No Author keywords available]

Indexed keywords

ADH GENE; ALCOHOLISM; ARTICLE; CHROMOSOME 4Q; CONTROLLED STUDY; DKK2 GENE; EGF GENE; GENE; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC RISK; HAPLOTYPE; HUMAN; IRELAND; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REGRESSION ANALYSIS; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 77955312372     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq112     Document Type: Article
Times cited : (15)

References (45)
  • 1
    • 0033930761 scopus 로고    scopus 로고
    • Genetics of the risk for alcoholism
    • Schuckit, M.A. (2000) Genetics of the risk for alcoholism. Am. J. Addict., 9, 103-112.
    • (2000) Am. J. Addict. , vol.9 , pp. 103-112
    • Schuckit, M.A.1
  • 3
    • 34247847741 scopus 로고    scopus 로고
    • The genetics of alcoholism: identifying specific genes through family studies
    • Edenberg, H.J. and Foroud, T. (2006) The genetics of alcoholism: identifying specific genes through family studies. Addict. Biol., 11, 386-396.
    • (2006) Addict. Biol. , vol.11 , pp. 386-396
    • Edenberg, H.J.1    Foroud, T.2
  • 5
    • 11044219969 scopus 로고    scopus 로고
    • Alcoholism: genes and mechanisms
    • Oroszi, G. and Goldman, D. (2004) Alcoholism: genes and mechanisms. Pharmacogenomics, 5, 1037-1048.
    • (2004) Pharmacogenomics , vol.5 , pp. 1037-1048
    • Oroszi, G.1    Goldman, D.2
  • 8
    • 33745659950 scopus 로고    scopus 로고
    • Genomewide linkage study in the Irish affected sib pair study of alcohol dependence: evidence for a susceptibility region for symptoms of alcohol dependence on chromosome 4
    • Prescott, C.A., Sullivan, P.F., Kuo, P.H., Webb, B.T., Vittum, J., Patterson, D.G., Thiselton, D.L., Myers, J.M., Devitt, M., Halberstadt, L.J. et al. (2006) Genomewide linkage study in the Irish affected sib pair study of alcohol dependence: evidence for a susceptibility region for symptoms of alcohol dependence on chromosome 4. Mol. Psychiatry, 11, 603-611.
    • (2006) Mol. Psychiatry , vol.11 , pp. 603-611
    • Prescott, C.A.1    Sullivan, P.F.2    Kuo, P.H.3    Webb, B.T.4    Vittum, J.5    Patterson, D.G.6    Thiselton, D.L.7    Myers, J.M.8    Devitt, M.9    Halberstadt, L.J.10
  • 9
    • 2142650784 scopus 로고    scopus 로고
    • Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology
    • Crabb, D.W., Matsumoto, M., Chang, D. and You, M. (2004) Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology. Proc. Nutr. Soc., 63, 49-63.
    • (2004) Proc. Nutr. Soc. , vol.63 , pp. 49-63
    • Crabb, D.W.1    Matsumoto, M.2    Chang, D.3    You, M.4
  • 12
    • 34547433163 scopus 로고    scopus 로고
    • The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants
    • Edenberg, H.J. (2007) The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants. Alcohol Res. Health, 30, 5-13.
    • (2007) Alcohol Res. Health , vol.30 , pp. 5-13
    • Edenberg, H.J.1
  • 15
    • 0036844535 scopus 로고    scopus 로고
    • Alcohol dehydrogenase and alcohol dependence: variation in genotype-associated risk between populations
    • author reply 1250-1251
    • Whitfield, J.B. (2002) Alcohol dehydrogenase and alcohol dependence: variation in genotype-associated risk between populations. Am. J. Hum. Genet., 71, 1247-1250. author reply 1250-1251.
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 1247-1250
    • Whitfield, J.B.1
  • 20
    • 10444284996 scopus 로고    scopus 로고
    • Elevated alpha synuclein mRNA levels are associated with craving in patients with alcoholism
    • Bonsch, D., Reulbach, U., Bayerlein, K., Hillemacher, T., Kornhuber, J. and Bleich, S. (2004) Elevated alpha synuclein mRNA levels are associated with craving in patients with alcoholism. Biol. Psychiatry, 56, 984-986.
    • (2004) Biol. Psychiatry , vol.56 , pp. 984-986
    • Bonsch, D.1    Reulbach, U.2    Bayerlein, K.3    Hillemacher, T.4    Kornhuber, J.5    Bleich, S.6
  • 24
    • 33646337898 scopus 로고    scopus 로고
    • When is a replication not a replication? Or how to spot a good genetic association study
    • Spector, T.D., Ahmadi, K.R. and Valdes, A.M. (2006) When is a replication not a replication? Or how to spot a good genetic association study. Arthritis Rheum., 54, 1051-1054.
    • (2006) Arthritis Rheum , vol.54 , pp. 1051-1054
    • Spector, T.D.1    Ahmadi, K.R.2    Valdes, A.M.3
  • 25
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • Lohmueller, K.E., Pearce, C.L., Pike, M., Lander, E.S. and Hirschhorn, J.N. (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat. Genet., 33, 177-182.
    • (2003) Nat. Genet. , vol.33 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 27
    • 34247642751 scopus 로고    scopus 로고
    • Spurious genetic associations
    • Sullivan, P.F. (2007) Spurious genetic associations. Biol. Psychiatry, 61, 1121-1126.
    • (2007) Biol. Psychiatry , vol.61 , pp. 1121-1126
    • Sullivan, P.F.1
  • 29
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: a common theme in animal development
    • Cadigan, K.M. and Nusse, R. (1997) Wnt signaling: a common theme in animal development. Genes Dev., 11, 3286-3305.
    • (1997) Genes Dev , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 30
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodarz, A. and Nusse, R. (1998) Mechanisms of Wnt signaling in development. Annu. Rev. Cell. Dev. Biol., 14, 59-88.
    • (1998) Annu. Rev. Cell. Dev. Biol. , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 31
    • 0036337388 scopus 로고    scopus 로고
    • Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins
    • Brott, B.K. and Sokol, S.Y. (2002) Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins. Mol. Cell. Biol., 22, 6100-6110.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6100-6110
    • Brott, B.K.1    Sokol, S.Y.2
  • 32
    • 9644262497 scopus 로고    scopus 로고
    • Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity
    • Buss, H., Dorrie, A., Schmitz, M.L., Frank, R., Livingstone, M., Resch, K. and Kracht, M. (2004) Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity. J. Biol. Chem., 279, 49571-49574.
    • (2004) J. Biol. Chem. , vol.279 , pp. 49571-49574
    • Buss, H.1    Dorrie, A.2    Schmitz, M.L.3    Frank, R.4    Livingstone, M.5    Resch, K.6    Kracht, M.7
  • 34
    • 34250333373 scopus 로고    scopus 로고
    • Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk
    • Dick, D.M., Agrawal, A., Wang, J.C., Hinrichs, A., Bertelsen, S., Bucholz, K.K., Schuckit, M., Kramer, J., Nurnberger, J. Jr, Tischfield, J. et al. (2007) Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk. Addiction, 102, 1131-1139.
    • (2007) Addiction , vol.102 , pp. 1131-1139
    • Dick, D.M.1    Agrawal, A.2    Wang, J.C.3    Hinrichs, A.4    Bertelsen, S.5    Bucholz, K.K.6    Schuckit, M.7    Kramer, J.8    Nurnberger J., Jr.9    Tischfield, J.10
  • 37
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett, J.C., Fry, B., Maller, J. and Daly, M.J. (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics, 21, 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 38
    • 0034601620 scopus 로고    scopus 로고
    • The stanley foundation brain collection and neuropathology consortium
    • Torrey, E.F., Webster, M., Knable, M., Johnston, N. and Yolken, R.H. (2000) The stanley foundation brain collection and neuropathology consortium. Schizophr. Res., 44, 151-155.
    • (2000) Schizophr. Res. , vol.44 , pp. 151-155
    • Torrey, E.F.1    Webster, M.2    Knable, M.3    Johnston, N.4    Yolken, R.H.5
  • 39
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak, K.J. and Schmittgen, T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods, 25, 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 40
    • 0035003174 scopus 로고    scopus 로고
    • A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR
    • Meijerink, J., Mandigers, C., van de Locht, L., Tonnissen, E., Goodsaid, F. and Raemaekers, J. (2001) A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR. J. Mol. Diagn., 3, 55-61.
    • (2001) J. Mol. Diagn. , vol.3 , pp. 55-61
    • Meijerink, J.1    Mandigers, C.2    van de Locht, L.3    Tonnissen, E.4    Goodsaid, F.5    Raemaekers, J.6
  • 41
    • 1242296154 scopus 로고    scopus 로고
    • Inhibition of real-time RT-PCR quantification due to tissue-specific contaminants
    • Tichopad, A., Didier, A. and Pfaffl, M.W. (2004) Inhibition of real-time RT-PCR quantification due to tissue-specific contaminants. Mol. Cell. Probes, 18, 45-50.
    • (2004) Mol. Cell. Probes , vol.18 , pp. 45-50
    • Tichopad, A.1    Didier, A.2    Pfaffl, M.W.3
  • 43
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt, D.R. (2004) A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am. J. Hum. Genet., 74, 765-769.
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 44
    • 0242691208 scopus 로고    scopus 로고
    • A comparison of bayesian methods for haplotype reconstruction from population genotype data
    • Stephens, M. and Donnelly, P. (2003) A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am. J. Hum. Genet., 73, 1162-1169.
    • (2003) Am. J. Hum. Genet. , vol.73 , pp. 1162-1169
    • Stephens, M.1    Donnelly, P.2
  • 45
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens, M., Smith, N.J. and Donnelly, P. (2001) A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet., 68, 978-989.
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.