Prevention of Escherichia coli K1 penetration of the blood-brain barrier by counteracting the host cell receptor and signaling molecule involved in E. coli invasion of human brain microvascular endothelial cells

Infection and Immunity

Volumn 78, Issue 8, 2010, Pages 3554-3559

  Zhu, Longkun ^a   Pearce, Donna ^a   Kim, Kwang Sik ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CYTOSOLIC PHOSPHOLIPASE A2; ESCHERICHIA COLI CYTOTOXIC NECROTIZING FACTOR 1; ESCHERICHIA COLI PROTEIN; ETOPOSIDE; LAMININ RECEPTOR; MONTELUKAST; OUTER MEMBRANE PROTEIN A; PEPTIDOLEUKOTRIENE; UNCLASSIFIED DRUG; ACETIC ACID DERIVATIVE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; QUINOLINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL MENINGITIS; BACTERIUM MUTANT; BLOOD BRAIN BARRIER; CELL INVASION; CONTROLLED STUDY; DISEASE MODEL; DRUG MECHANISM; ENDOTHELIUM CELL; ESCHERICHIA COLI; ESCHERICHIA COLI K1; FLUORESCENCE ACTIVATED CELL SORTING; HOST CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VASCULAR ENDOTHELIUM; ANIMAL; BRAIN; CELL CULTURE; DRUG ANTAGONISM; FEMALE; MICROBIOLOGY; NEWBORN; PATHOGENICITY; SPRAGUE DAWLEY RAT;

ACETATES; ANIMALS; ANIMALS, NEWBORN; BLOOD-BRAIN BARRIER; BRAIN; CELLS, CULTURED; ENDOTHELIAL CELLS; ESCHERICHIA COLI; ETOPOSIDE; FEMALE; HUMANS; LEUKOTRIENE ANTAGONISTS; MENINGITIS, ESCHERICHIA COLI; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LAMININ;

EID: 77955300764     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00336-10     Document Type: Article

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