Secreted Aspergillus fumigatus protease Alp1 degrades human complement proteins C3, C4, and C5

Infection and Immunity

Volumn 78, Issue 8, 2010, Pages 3585-3594

  Behnsen, Judith ^a,b   Lessing, Franziska ^a,b   Schindler, Susann ^a,b   Wartenberg, Dirk ^a,b   Jacobsen, Ilse D ^a   Thoen, Marcel ^a,b   Zipfel, Peter F ^a,b   Brakhage, Axel A ^a,b  

^a HANS KNÖLL INSTITUTE   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PROTEINASE; ALP1 ENZYME; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C5; CORTISONE ACETATE; IMMUNOGLOBULIN G; NITROGEN; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; COMPLEMENT COMPONENT C1Q; FUNGAL PROTEIN; ORYZIN; SERINE PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CARBON SOURCE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; ENZYME RELEASE; FUNGAL VIRULENCE; FUNGUS CULTURE; FUNGUS HYPHAE; GENE DELETION; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; ANIMAL; ENZYMOLOGY; ESCHERICHIA COLI; FEMALE; GENETICS; HUMAN; IMMUNE EVASION; IMMUNOLOGY; METABOLISM;

ANIMALS; ASPERGILLUS FUMIGATUS; COMPLEMENT C1Q; COMPLEMENT C3; COMPLEMENT C4; COMPLEMENT C5; ESCHERICHIA COLI; FEMALE; FUNGAL PROTEINS; GENE DELETION; HUMANS; HYPHAE; IMMUNE EVASION; IMMUNOGLOBULIN G; MICE; SERINE ENDOPEPTIDASES;

EID: 77955297653     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01353-09     Document Type: Article

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