Growth hormone mitigates against lethal irradiation and enhances hematologic and immune recovery in mice and nonhuman primates

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Chen, Benny J ^a   Deoliveira, Divino ^a   Spasojevic, Ivan ^a   Sempowski, Gregory D ^a   Jiang, Chen ^a   Owzar, Kouros ^a   Wang, Xiaojuan ^a   Gesty Palmer, Diane ^a   Mark Cline, J ^b   Daniel Bourland, J ^b   Dugan, Greg ^b   Meadows, Sarah K ^a   Daher, Pamela ^a   Muramoto, Garrett ^a   Chute, John P ^a   Chao, Nelson J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT GROWTH HORMONE; SOMATOMEDIN C; GROWTH HORMONE; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BURST FORMING UNIT E; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COLONY FORMING UNIT GEMM; COLONY FORMING UNIT GM; CONTROLLED STUDY; FEMALE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; IMMUNE RESPONSE; LEUKOCYTE COUNT; MACACA; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; RADIATION INJURY; RADIATION PROTECTION; STEM CELL NICHE; SURVIVAL RATE; THROMBOCYTE COUNT; ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; C57BL MOUSE; DRUG EFFECT; PRIMATE; T LYMPHOCYTE SUBPOPULATION;

MUS; PRIMATES;

ANIMALS; APOPTOSIS; GROWTH HORMONE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PRIMATES; RADIATION INJURIES, EXPERIMENTAL; RECOMBINANT PROTEINS; T-LYMPHOCYTE SUBSETS;

EID: 77955295189     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011056     Document Type: Article

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