Inhibition of Golgi apparatus glycosylation causes endoplasmic reticulum stress and decreased protein synthesis

Journal of Biological Chemistry

Volumn 285, Issue 32, 2010, Pages 24600-24608

  Xu, Yu Xin ^a   Liu, Li ^a   Caffaro, Carolina E ^a,b   Hirschberg, Carlos B ^a  

^a BOSTON UNIVERSITY   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CARBOHYDRATES; CARBOXYLIC ACIDS; CELL MEMBRANES; ESTERIFICATION; GLYCOPROTEINS; GLYCOSYLATION; ORGANIC ACIDS; SUGAR (SUCROSE);

DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; GLYCOCONJUGATES; GOLGI APPARATUS; METABOLIC CHANGES; NUCLEOTIDE SUGAR TRANSPORTERS; PLASMA MEMBRANES; PROTEIN SYNTHESIS; PROTEIN TRANSLATION; PROTEOGLYCANS; SIALIC ACIDS;

PROTEINS;

CMP SIALIC ACID TRANSPORTER; GLYCOPROTEIN; GUANOSINE DIPHOSPHATE FUCOSE TRANSPORTER; NUCLEOTIDE TRANSPORTER; SMALL INTERFERING RNA; SUGAR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL LYSATE; CHO CELL; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; GENETIC TRANSFECTION; GLYCOSYLATION; GOLGI COMPLEX; HELA CELL; IMMUNOFLUORESCENCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSLATION INITIATION; ANIMAL; BIOLOGICAL MODEL; CHO CELL LINE; CONFOCAL MICROSCOPY; CRICETULUS; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; HAMSTER; HELA CELL LINE; HUMAN; METABOLISM; PROCEDURES; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CHO CELLS; CRICETINAE; CRICETULUS; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; GLYCOSYLATION; GOLGI APPARATUS; HELA CELLS; HUMANS; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; PROTEIN BIOSYNTHESIS; RNA, SMALL INTERFERING;

EID: 77955289215     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.134544     Document Type: Article

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