-
1
-
-
0021143782
-
Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: A distinctive clinical syndrome
-
Pavlakis, S.G., P.C. Phillips, S. DiMauro, et al. 1984. Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: a distinctive clinical syndrome. Ann. Neurol. 16: 481-488.
-
(1984)
Ann. Neurol.
, vol.16
, pp. 481-488
-
-
Pavlakis, S.G.1
Phillips, P.C.2
Di Mauro, S.3
-
2
-
-
77949433548
-
Pathophysiology of stroke-like episodes in MELAS: Neuron-astrocyte uncoupling in neuronal hyperexcitability
-
Iizuka, T. & F. Sakai. 2010. Pathophysiology of stroke-like episodes in MELAS: neuron-astrocyte uncoupling in neuronal hyperexcitability. Future Neurol. 5: 61-83.
-
(2010)
Future Neurol.
, vol.5
, pp. 61-83
-
-
Iizuka, T.1
Sakai, F.2
-
3
-
-
0025666322
-
A mutation in the tRNA (Leu(UUR)) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies
-
Goto, Y.I., I. Nonaka & S. Horai. 1990. A mutation in the tRNA (Leu(UUR)) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies. Nature 348: 651-653.
-
(1990)
Nature
, vol.348
, pp. 651-653
-
-
Goto, Y.I.1
Nonaka, I.2
Horai, S.3
-
4
-
-
0026708671
-
Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS): A correlative study of the clinical features and mitochondrial DNA mutation
-
Goto, Y.I., S. Horai, T. Matsuoka, et al. 1992. Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS): a correlative study of the clinical features and mitochondrial DNA mutation. Neurology 42: 545-550.
-
(1992)
Neurology
, vol.42
, pp. 545-550
-
-
Goto, Y.I.1
Horai, S.2
Matsuoka, T.3
-
5
-
-
0023270881
-
Mitochondrial angiopathy in cerebral blood vessels of mitochondrial encephalomyopathy
-
Ohama, E., S. Ohara, F. Ikuta, K. Tanaka, et al. 1987. Mitochondrial angiopathy in cerebral blood vessels of mitochondrial encephalomyopathy. Acta Neuropathol. 74: 226-233.
-
(1987)
Acta Neuropathol
, vol.74
, pp. 226-233
-
-
Ohama, E.1
Ohara, S.2
Ikuta, F.3
Tanaka, K.4
-
6
-
-
0023810655
-
An autopsy case of mitochondrial encephalomyopathy: Biochemical and electron microscopic studies of the brain
-
Kishi, M., Y. Yamamura, T. Kurihara, et al. 1988. An autopsy case of mitochondrial encephalomyopathy: biochemical and electron microscopic studies of the brain. J. Neurol. Sci. 86: 31-40.
-
(1988)
J. Neurol. Sci.
, vol.86
, pp. 31-40
-
-
Kishi, M.1
Yamamura, Y.2
Kurihara, T.3
-
7
-
-
0025825012
-
Strongly succinate dehydrogenase-reactive blood vessels in muscles from patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes
-
Hasegawa, H., T. Matsuoka, Y. Goto & I. Nonaka. 1991. Strongly succinate dehydrogenase-reactive blood vessels in muscles from patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes. Ann. Neurol. 29: 601-605.
-
(1991)
Ann. Neurol.
, vol.29
, pp. 601-605
-
-
Hasegawa, H.1
Matsuoka, T.2
Goto, Y.3
Nonaka, I.4
-
8
-
-
0037066134
-
Effects of L-arginine on the acute phase of strokes in three patients with MELAS
-
Koga, Y., M. Ishibashi, I. Ueki, S. Yatsuga, et al. 2002. Effects of L-arginine on the acute phase of strokes in three patients with MELAS. Neurology 58: 827-828.
-
(2002)
Neurology
, vol.58
, pp. 827-828
-
-
Koga, Y.1
Ishibashi, M.2
Ueki, I.3
Yatsuga, S.4
-
9
-
-
13844321746
-
L-arginine improves the symptoms of stroke-like episodes in MELAS
-
Koga, Y., Y. Akita, J. Nishioka, et al. 2005. L-arginine improves the symptoms of stroke-like episodes in MELAS. Neurology 64: 710-712.
-
(2005)
Neurology
, vol.64
, pp. 710-712
-
-
Koga, Y.1
Akita, Y.2
Nishioka, J.3
-
10
-
-
34250833548
-
Genetic, pathogenic, and phenotypic implications of the mitochondrial A3243 G tRNALeu(UUR) mutation
-
Finsterer, J. 2007. Genetic, pathogenic, and phenotypic implications of the mitochondrial A3243 G tRNALeu(UUR) mutation. Acta Neurol. Scand. 116: 1-14.
-
(2007)
Acta Neurol. Scand.
, vol.116
, pp. 1-14
-
-
Finsterer, J.1
-
11
-
-
0026608057
-
MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts
-
Chomyn, A., A.Martinuzzi,M. Yoneda, et al. 1992. MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts.Proc.Natl.Acad. Sci.USA89: 4221-4225.
-
(1992)
Proc.Natl.Acad Sci.USA
, vol.89
, pp. 4221-4225
-
-
Chomyn, A.1
Martinuzzi, A.2
Yoneda, M.3
-
12
-
-
0034635519
-
Modification defect at anticodon wobble nucleotide of mitochondrial tRNAs( Leu)(UUR) with pathogenic mutations of mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes
-
Yasukawa, T., T. Suzuki, T. Suzuki, et al. 2000. Modification defect at anticodon wobble nucleotide of mitochondrial tRNAs( Leu)(UUR) with pathogenic mutations of mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. J. Biol. Chem. 275: 4251-4257.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4251-4257
-
-
Yasukawa, T.1
Suzuki, T.2
Suzuki, T.3
-
13
-
-
0026573082
-
Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrialmyopathy, encephalopathy, lactic acidosis, and strokelike episodes
-
King,M.P.,Y.Koga,M.Davidson & E.A. Schon. 1992. Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrialmyopathy, encephalopathy, lactic acidosis, and strokelike episodes.Mol.Cell.Biol. 12: 480-490.
-
(1992)
Mol.Cell.Biol.
, vol.12
, pp. 480-490
-
-
King, M.P.1
Koga, Y.2
Davidson, M.3
Schon, E.A.4
-
14
-
-
17744421507
-
MELAS exhibits dominant negative effects on mitochondrial RNA processing
-
Koga, Y., M. Yoshino & H. Kato. 1998. MELAS exhibits dominant negative effects on mitochondrial RNA processing. Ann. Neurol. 43: 835.
-
(1998)
Ann. Neurol.
, vol.43
, pp. 835
-
-
Koga, Y.1
Yoshino, M.2
Kato, H.3
-
15
-
-
0037373665
-
Increased mitochondrial processing intermediates associated with threet RNALeu(UUR) gene mutations
-
Koga, Y., A. Koga, Y. Akita, R. Fukiyama, et al. 2003. Increased mitochondrial processing intermediates associated with threet RNALeu(UUR) gene mutations. Neuromuscul. Disord. 13: 259-262.
-
(2003)
Neuromuscul. Disord.
, vol.13
, pp. 259-262
-
-
Koga, Y.1
Koga, A.2
Akita, Y.3
Fukiyama, R.4
-
16
-
-
0024269520
-
Findings in muscle in complex i (NADH Coenzyme Q reductase) deficiency
-
Koga, Y., I. Nonaka, M. Kobayashi, et al. 1988. Findings in muscle in complex I (NADH Coenzyme Q reductase) deficiency. Ann. Neurol. 24: 749-756.
-
(1988)
Ann. Neurol.
, vol.24
, pp. 749-756
-
-
Koga, Y.1
Nonaka, I.2
Kobayashi, M.3
-
17
-
-
25844460500
-
Distinct nuclear gene expression profiles in the cells with mt DNA depletion and homoplasmic A3243G mutation
-
Jahangier Tafewchi, R.S., P.J. Svenson, G.M. Janssen, et al. 2005. Distinct nuclear gene expression profiles in the cells with mtDNA depletion and homoplasmic A3243G mutation. Mutat. Res. 578: 43-52.
-
(2005)
Mutat. Res.
, vol.578
, pp. 43-52
-
-
Jahangier Tafewchi, R.S.1
Svenson, P.J.2
Janssen, G.M.3
-
18
-
-
0024343409
-
Vascular involvement in mitochondrial myopathy
-
Sakuta, R. & I. Nonaka. 1989. Vascular involvement in mitochondrial myopathy. Ann. Neurol. 25: 594-601.
-
(1989)
Ann. Neurol.
, vol.25
, pp. 594-601
-
-
Sakuta, R.1
Nonaka, I.2
-
19
-
-
14844303949
-
Hypocitrullinemia in patients with MELAS: An insight into the "mELAS paradox"
-
Naini, A., P. Kaufmann, S. Shanske, et al. 2005. Hypocitrullinemia in patients with MELAS: an insight into the "MELAS paradox". J. Neurol. Sci. 229-230: 187-193.
-
(2005)
J. Neurol. Sci.
, vol.229-230
, pp. 187-193
-
-
Naini, A.1
Kaufmann, P.2
Shanske, S.3
-
20
-
-
0033966736
-
MELAS with the mitochondrial DNA 3243 point mutation: A neuropathological study
-
Tanahashi, C., A.Nakayama,M. Yoshida, et al. 2000. MELAS with the mitochondrial DNA 3243 point mutation: a neuropathological study. Acta Neuropathol. 99: 31-38.
-
(2000)
Acta Neuropathol.
, vol.99
, pp. 31-38
-
-
Tanahashi, C.1
Nakayama, A.2
Yoshida, M.3
-
21
-
-
34249829899
-
Regional cerebral blood flow and cerebrovascular reactivity during chronic stage of stroke-like episodes in MELAS-implication of neurovascular cellular mechanism
-
Iizuka, T., F. Sakai, T. Ide, et al. 2007. Regional cerebral blood flow and cerebrovascular reactivity during chronic stage of stroke-like episodes in MELAS-implication of neurovascular cellular mechanism. J. Neurol. Sci. 257: 126-138.
-
(2007)
J. Neurol. Sci.
, vol.257
, pp. 126-138
-
-
Iizuka, T.1
Sakai, F.2
Ide, T.3
-
22
-
-
21344437783
-
Stroke-like episode involving a cerebral artery in a patient withMELAS
-
Noguchi,A., Y. Shoji, M. Matsumori, et al. 2005. Stroke-like episode involving a cerebral artery in a patient withMELAS. Pediatr. Neurol. 33: 70-71.
-
(2005)
Pediatr. Neurol.
, vol.33
, pp. 70-71
-
-
Noguchi, A.1
Shoji, Y.2
Matsumori, M.3
-
23
-
-
58749101320
-
Progressive carotid artery stenosis with a novelt RNA phenylalanine mitochondrial DNA mutation
-
Iizuka, T., Y. Goto, S. Miyakawa, et al. 2009. Progressive carotid artery stenosis with a novelt RNA phenylalanine mitochondrial DNA mutation. J. Neurol. Sci. 278: 35-40.
-
(2009)
J. Neurol. Sci.
, vol.278
, pp. 35-40
-
-
Iizuka, T.1
Goto, Y.2
Miyakawa, S.3
-
24
-
-
4444325550
-
Beneficial effect of L-arginine for stroke-like episode inMELAS
-
Kubota, M., Y. Sakakihara, M. Mori, et al. 2004. Beneficial effect of L-arginine for stroke-like episode inMELAS. Brain Dev. 26: 481-483.
-
(2004)
Brain Dev.
, vol.26
, pp. 481-483
-
-
Kubota, M.1
Sakakihara, Y.2
Mori, M.3
-
25
-
-
0032724863
-
Quantitative proton magnetic resonance spectroscopy of cerebral metabolic disturbances in patients with MELAS
-
Wilichowski, E., P.J. Pouwels, J. Frahm & F. Hanefeld. 1999. Quantitative proton magnetic resonance spectroscopy of cerebral metabolic disturbances in patients with MELAS. Neuropediatrics 30: 256-263.
-
(1999)
Neuropediatrics
, vol.30
, pp. 256-263
-
-
Wilichowski, E.1
Pouwels, P.J.2
Frahm, J.3
Hanefeld, F.4
-
26
-
-
11144355448
-
Cerebral lactic acidosis correlates with neurological impairment in MELAS
-
Kaufmann, P.,D.C. Shungu,M.C. Sano, et al. 2004. Cerebral lactic acidosis correlates with neurological impairment in MELAS. Neurology 62: 1297-1302.
-
(2004)
Neurology
, vol.62
, pp. 1297-1302
-
-
Kaufmann, P.1
Shungu, D.C.2
Sano, M.C.3
-
27
-
-
33745648369
-
Endothelial dysfunction in MELAS was improved by L-arginine supplementation
-
Koga, Y., Y. Akita, N. Junko, et al. 2006. Endothelial dysfunction in MELAS was improved by L-arginine supplementation. Neurology 66: 1766-1769.
-
(2006)
Neurology
, vol.66
, pp. 1766-1769
-
-
Koga, Y.1
Akita, Y.2
Junko, N.3
-
28
-
-
38749123431
-
Inappropriate intracranial hemodynamics in the natural course ofMELAS
-
Nishioka, J., Y. Akita, S. Yatsuga, et al. 2008. Inappropriate intracranial hemodynamics in the natural course ofMELAS. Brain Dev. 30: 100-105.
-
(2008)
Brain Dev.
, vol.30
, pp. 100-105
-
-
Nishioka, J.1
Akita, Y.2
Yatsuga, S.3
-
29
-
-
62549084242
-
PETimaging of redox and energy states in stroke-like episodes of MELAS
-
Ikawa,M.,H.Okazawa,K.Arakawa, et al. 2009. PETimaging of redox and energy states in stroke-like episodes of MELAS. Mitochondrion 9: 144-148.
-
(2009)
Mitochondrion
, vol.9
, pp. 144-148
-
-
Ikawa, M.1
Okazawa, H.2
Arakawa, K.3
-
30
-
-
0034943090
-
Discordance between cerebral oxygen and glucose metabolism, and hemodynamics in a mitochondrial encephalomyopathy, lactic acidosis, and strokelike episode patient
-
Nariai,T., K. Ohno,Y.Ohta, et al. 2001. Discordance between cerebral oxygen and glucose metabolism, and hemodynamics in a mitochondrial encephalomyopathy, lactic acidosis, and strokelike episode patient. J.Neuroimaging 11: 325-329.
-
(2001)
J.Neuroimaging
, vol.11
, pp. 325-329
-
-
Nariai, T.1
Ohno, K.2
Ohta, Y.3
-
31
-
-
0033837143
-
Cerebral blood flow and glucose metabolism in mitochondrial disorders
-
Molńar, M.J., A. Valikovics, S. Molńar, et al. 2000. Cerebral blood flow and glucose metabolism in mitochondrial disorders. Neurology 55: 544-548.
-
(2000)
Neurology
, vol.55
, pp. 544-548
-
-
Molńar, M.J.1
Valikovics, A.2
Molńar, S.3
-
32
-
-
1542269064
-
Middle cerebral artery occlusion during MR-imaging: Investigation of the hyperacute phase of stroke using a new in-bore occlusion model in rats
-
Gerriets,T., E. Stolz,M.Walberer, et al. 2004.Middle cerebral artery occlusion during MR-imaging: investigation of the hyperacute phase of stroke using a new in-bore occlusion model in rats. Brain Res. Protoc. 12: 137-143.
-
(2004)
Brain Res. Protoc.
, vol.12
, pp. 137-143
-
-
Gerriets, T.1
Stolz, E.2
Walberer, M.3
-
33
-
-
0033809548
-
Serial diffusionweighted imaging in MELAS
-
Ohshita, T., M. Oka, Y. Imon, et al. 2000. Serial diffusionweighted imaging in MELAS. Neuroradiology 42: 651-656.
-
(2000)
Neuroradiology
, vol.42
, pp. 651-656
-
-
Ohshita, T.1
Oka, M.2
Imon, Y.3
-
34
-
-
45849142222
-
Serial brain imaging analysis of stroke-like episodes in MELAS
-
Ito,H., K.Mori,M.Harada, et al. 2008. Serial brain imaging analysis of stroke-like episodes in MELAS. Brain Dev. 30: 483-488.
-
(2008)
Brain Dev.
, vol.30
, pp. 483-488
-
-
Ito, H.1
Mori, K.2
Harada, M.3
-
35
-
-
0141955033
-
Serial diffusion-weighted imaging in a patient with MELAS and presumed cytotoxic oedema
-
Wang, X.Y., K. Noguchi, S. Takashima, et al. 2003. Serial diffusion-weighted imaging in a patient with MELAS and presumed cytotoxic oedema. Neuroradiology 45: 640-643.
-
(2003)
Neuroradiology
, vol.45
, pp. 640-643
-
-
Wang, X.Y.1
Noguchi, K.2
Takashima, S.3
-
36
-
-
56349124138
-
MRI and diffusion-weighted imaging followup of a stroke-like event in a patient with MELAS
-
Stoquart-Elsankari, S., P. Lehmann,B. Ṕerin, et al. 2008.MRI and diffusion-weighted imaging followup of a stroke-like event in a patient with MELAS. J. Neurol. 255: 1593-1595.
-
(2008)
J. Neurol.
, vol.255
, pp. 1593-1595
-
-
Stoquart-Elsankari, S.1
Lehmann, P.2
Ṕerin, B.3
-
37
-
-
0030048029
-
A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene
-
WangD, X.L., A.S. Sim, R.F. Badenhop, et al. 1996. A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene. Nat. Med. 2: 41-45.
-
(1996)
Nat. Med.
, vol.2
, pp. 41-45
-
-
Wangd, X.L.1
Sim, A.S.2
Badenhop, R.F.3
-
38
-
-
67849115937
-
Larginine efficiency in MELAS syndrome
-
Paris, in French
-
Moutaouakil, F., H. El Otmani, H. Fadel, et al. 2009. Larginine efficiency in MELAS syndrome. A case report. Rev. Neurol. (Paris) 165: 482-485. (in French)
-
(2009)
A Case Report. Rev. Neurol.
, vol.165
, pp. 482-485
-
-
Moutaouakil, F.1
El Otmani, H.2
Fadel, H.3
-
39
-
-
49949087968
-
Newindications and controversies in arginine therapy
-
Coman,D., J. Yaplito-Lee & A. Boneh. 2008.Newindications and controversies in arginine therapy. Clin. Nutr. 27: 489-496.
-
(2008)
Clin. Nutr.
, vol.27
, pp. 489-496
-
-
Coman, D.1
Yaplito-Lee, J.2
Boneh, A.3
|